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The map label for this gene is yfcG [H]

Identifier: 108758218

GI number: 108758218

Start: 981202

End: 981828

Strand: Reverse

Name: yfcG [H]

Synonym: MXAN_0864

Alternate gene names: 108758218

Gene position: 981828-981202 (Counterclockwise)

Preceding gene: 108757190

Following gene: 108762089

Centisome position: 10.74

GC content: 66.19

Gene sequence:

>627_bases
ATGATCGACCTCTACACGTTCGCGACGCCCAACGGACAGAAGGTATCCATCGCCCTGGAGGAGCTGGGCCTCCAGTACAA
GACGCATGTGGTGGACATCACCAAGGGCGAGCAGTTCAAGCCCGAGTTCCTGGACATCAACCCCAACAACAAGATTCCGG
CCATCGTCGACCACGCGACGCAGGACCACCGTCCGCTCAAGGTCTTCGAGTCCGGCGCCATCCTCATCTACCTGGCGGAG
AAGACGGGCCAGCTGCTGCCCTCCAACCAGCGCGGCCGGGCGGAAGTGATGGAGTGGCTGATGTTCCAGATGGGCGGCGT
GGGGCCCATGTTCGGCCAGCTCTACCACTTCGCCCGCTTCGCCCCCAAGAAGGTCCCCTACGGCATCGAGCGTTATCACG
CCGAGTCCCGGCGGCTCGTCGGCGTGCTCGACGGGAAGCTGGGCTCCGGGGATTACGTCGCGGGCCGCTACTCCATCGCG
GACATCGCGCTGTATCCCTGGGTGGCCGGCGCCCGCGCGAGCTTCCCCGAGCTGTTCCGGGGGAACAGCAACGTCGTGCA
GTGGCTCCACCGCGTGGGCAGCCGGCCCGCCGTGGAGCGCGGCATGAAGGTCCCCCAGCTCAAGTAG

Upstream 100 bases:

>100_bases
TCTACAAATGCCGTCCGAAGAAGCCGTCCTCCGCCGCGCGGAACGACGCGCTCGCGGAGCGGCTCTGGCAGGTGAGCGAG
CAGCTCACGGGAGTCAAGGG

Downstream 100 bases:

>100_bases
TCCCACACAGCTTCCCGGAAGCGCGGTGGCTGGATGGCCGCCGCGCTTCCATGTGTTCTCCTCCGTCATGGCCACGCTCG
AACAACTCCGCTTCGACAAC

Product: glutathione S-transferase domain-containing protein

Products: NA

Alternate protein names: GST-like protein yfcG [H]

Number of amino acids: Translated: 208; Mature: 208

Protein sequence:

>208_residues
MIDLYTFATPNGQKVSIALEELGLQYKTHVVDITKGEQFKPEFLDINPNNKIPAIVDHATQDHRPLKVFESGAILIYLAE
KTGQLLPSNQRGRAEVMEWLMFQMGGVGPMFGQLYHFARFAPKKVPYGIERYHAESRRLVGVLDGKLGSGDYVAGRYSIA
DIALYPWVAGARASFPELFRGNSNVVQWLHRVGSRPAVERGMKVPQLK

Sequences:

>Translated_208_residues
MIDLYTFATPNGQKVSIALEELGLQYKTHVVDITKGEQFKPEFLDINPNNKIPAIVDHATQDHRPLKVFESGAILIYLAE
KTGQLLPSNQRGRAEVMEWLMFQMGGVGPMFGQLYHFARFAPKKVPYGIERYHAESRRLVGVLDGKLGSGDYVAGRYSIA
DIALYPWVAGARASFPELFRGNSNVVQWLHRVGSRPAVERGMKVPQLK
>Mature_208_residues
MIDLYTFATPNGQKVSIALEELGLQYKTHVVDITKGEQFKPEFLDINPNNKIPAIVDHATQDHRPLKVFESGAILIYLAE
KTGQLLPSNQRGRAEVMEWLMFQMGGVGPMFGQLYHFARFAPKKVPYGIERYHAESRRLVGVLDGKLGSGDYVAGRYSIA
DIALYPWVAGARASFPELFRGNSNVVQWLHRVGSRPAVERGMKVPQLK

Specific function: Has disulfide bond reductase activity (in vitro). Has low hydroperoxidase activity with cumene hydroperoxide. Has very low glutathione-S-transferase activity (in vitro) [H]

COG id: COG0625

COG function: function code O; Glutathione S-transferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 GST N-terminal domain [H]

Homologues:

Organism=Escherichia coli, GI1788640, Length=209, Percent_Identity=50.2392344497608, Blast_Score=197, Evalue=3e-52,
Organism=Escherichia coli, GI87082195, Length=216, Percent_Identity=43.0555555555556, Blast_Score=166, Evalue=1e-42,
Organism=Saccharomyces cerevisiae, GI6324100, Length=242, Percent_Identity=31.404958677686, Blast_Score=120, Evalue=1e-28,
Organism=Drosophila melanogaster, GI28571670, Length=147, Percent_Identity=33.3333333333333, Blast_Score=80, Evalue=7e-16,
Organism=Drosophila melanogaster, GI17864592, Length=192, Percent_Identity=32.2916666666667, Blast_Score=80, Evalue=7e-16,
Organism=Drosophila melanogaster, GI17933730, Length=202, Percent_Identity=29.7029702970297, Blast_Score=80, Evalue=1e-15,
Organism=Drosophila melanogaster, GI85725204, Length=194, Percent_Identity=30.4123711340206, Blast_Score=75, Evalue=4e-14,
Organism=Drosophila melanogaster, GI17737923, Length=194, Percent_Identity=30.4123711340206, Blast_Score=75, Evalue=4e-14,
Organism=Drosophila melanogaster, GI17864594, Length=169, Percent_Identity=33.1360946745562, Blast_Score=75, Evalue=4e-14,
Organism=Drosophila melanogaster, GI17864598, Length=157, Percent_Identity=34.3949044585987, Blast_Score=71, Evalue=4e-13,
Organism=Drosophila melanogaster, GI24646249, Length=184, Percent_Identity=31.5217391304348, Blast_Score=70, Evalue=6e-13,
Organism=Drosophila melanogaster, GI221378983, Length=193, Percent_Identity=29.5336787564767, Blast_Score=69, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24646259, Length=193, Percent_Identity=29.5336787564767, Blast_Score=69, Evalue=3e-12,
Organism=Drosophila melanogaster, GI17864596, Length=180, Percent_Identity=28.8888888888889, Blast_Score=68, Evalue=3e-12,
Organism=Drosophila melanogaster, GI24646251, Length=112, Percent_Identity=35.7142857142857, Blast_Score=65, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010987
- InterPro:   IPR004045
- InterPro:   IPR017933
- InterPro:   IPR004046
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF00043 GST_C; PF02798 GST_N [H]

EC number: NA

Molecular weight: Translated: 23328; Mature: 23328

Theoretical pI: Translated: 9.79; Mature: 9.79

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIDLYTFATPNGQKVSIALEELGLQYKTHVVDITKGEQFKPEFLDINPNNKIPAIVDHAT
CEEEEEEECCCCCEEEEEHHHHCCEEEEEEEEECCCCCCCCCEEEECCCCCCCEEEECCC
QDHRPLKVFESGAILIYLAEKTGQLLPSNQRGRAEVMEWLMFQMGGVGPMFGQLYHFARF
CCCCCEEEECCCEEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHH
APKKVPYGIERYHAESRRLVGVLDGKLGSGDYVAGRYSIADIALYPWVAGARASFPELFR
CCCCCCCCHHHHHHCCCEEEEEECCCCCCCCEEECEEEHHHEEECCCCCCCCCCCHHHHC
GNSNVVQWLHRVGSRPAVERGMKVPQLK
CCHHHHHHHHHHCCCHHHHHCCCCCCCC
>Mature Secondary Structure
MIDLYTFATPNGQKVSIALEELGLQYKTHVVDITKGEQFKPEFLDINPNNKIPAIVDHAT
CEEEEEEECCCCCEEEEEHHHHCCEEEEEEEEECCCCCCCCCEEEECCCCCCCEEEECCC
QDHRPLKVFESGAILIYLAEKTGQLLPSNQRGRAEVMEWLMFQMGGVGPMFGQLYHFARF
CCCCCEEEECCCEEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHH
APKKVPYGIERYHAESRRLVGVLDGKLGSGDYVAGRYSIADIALYPWVAGARASFPELFR
CCCCCCCCHHHHHHCCCEEEEEECCCCCCCCEEECEEEHHHEEECCCCCCCCCCCHHHHC
GNSNVVQWLHRVGSRPAVERGMKVPQLK
CCHHHHHHHHHHCCCHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9205837; 9278503 [H]