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The map label for this gene is resE [H]

Identifier: 108757911

GI number: 108757911

Start: 1149185

End: 1150645

Strand: Direct

Name: resE [H]

Synonym: MXAN_0993

Alternate gene names: 108757911

Gene position: 1149185-1150645 (Clockwise)

Preceding gene: 108759659

Following gene: 108760797

Centisome position: 12.57

GC content: 71.25

Gene sequence:

>1461_bases
ATGCCTCCCACTTCCGCGCTCATCCTCAACGTCAACGACGACGCGGCCAGCCGCTATGTCACCTCCCGCGTGCTGGGGCT
CGCGGGCTTCCGCGTCGTGGACGCCGCCTCCGGGATGGAGGCGCTTGCCCTGGTGACCGAGGACACGGACCTCGTCATCC
TGGACGTGCGGCTGCCGGACACCAGCGGCCTGGAGGTGTGCCGGAGGTTGAAGGAGACGCCTCGCACGCAGGGTGTCCTG
GTGCTCCACCTGTCCGCACAGGCCGTGGGACCGGGCGATCGGGCGCAGGGCCTGGAGCACGGCGCGGACGGCTACCTGGT
GGCGCCGGTGGACCCGGAGGAACTGGTGGCCCAGGTCCACGCGCTGCTCCGGCTGCGCCAGGCCGAGCGCGAGGTGAAGG
CGCTGTCCCGCGAGGTGGTGCACCAGCGCCAGCTCCTGGAGTTGGCCATCTCCTGCGCGGCGGACCCCATCGCGCTCTAC
GACGAGGCCGGGCGAGTCCTGTCGGCCAATCAGTCTCTGTATGCGTCACGCGGCAGCCACGCCGTGCATGCACCGGGCAG
GACACTGGATGAGATGCAGGCCGCGGATGGGGCGCTGACGCCGTACCTCGAACAGGTGCGGGTGGCCCTTCGCACGGGGC
AGGTGCAGCGAGGCACCATGGTCTTGGGTTCGGACCGGGGCCCGCGGTACTTCGACTACGTCCTGTCGCCCGCGCTGGGG
GCCGGCGGCGAGGTGCTGGCGGTGATGTCCTCCCTGCGGGACGTCACGGAGTCGCGCAGCGCGGAGGAGTTCCGCGAGCA
GTTCATCGGCATGTTGGGGCATGACCTGCGCAACCCGCTCAACGCGCTGTCCATGTCCGCGCAGCAGTTGCGGCGCAAGG
GTGGGCTGGACGAGCGCCAGGGCATGCTCACCGAGCGCATCCTCACCAGCGCCGAGCGCATGGACCGGATGATTCGCCAA
CTGCTGGACTTCGCGCGCTCGCGGCTGGGCGGCGGCATTCCGGTGGTGCGCTCGTCGTGCGACGTGTTCGAGGTGGTGCG
CCGCACCGTGGACGAACTGCGCGCCAGCCATCCTGGCCGGGTGGTGGAACTGGAGTCCAAGGGCGATGGCCTGGGGAAGT
GGGACTTCGACCGCCTGGAGCAGGCCGTGGGCAACCTGGTGGCCAACGCGCTGAAGTACAGCCCGGCGGAGAGCACCGTG
AGGGTGGGCGCCGAGGGCTCCGAGCGCGAGGTGGTGCTGCGCGTCCACAACCGTGGCACGCCCATCCCCGCGGAGGACCT
GCCCCACGTCTTCGGCGCCTGGCGCCGGGGCCGGCGCGCCGCCAGTGACGCGGGCGCGCCCAGCGGCCTGGGGTTGGGCC
TCGACATCACCCGGCAGATTGTCCGGGCGCATGACGGGGACGCGCAGGTGGCCTCCAGTGCGACGGAGGGCACGACCTTC
CTCATTCGCCTGCCACGATGA

Upstream 100 bases:

>100_bases
GCTTGTGTGCCTGCCCCGACAGCGCGCCCGTTGGTGCCCGTAACATCTGGCGTTCAGGCGGAGGCGCGGCTACGAAAGAG
CCTGACCCGCACACTTCCGT

Downstream 100 bases:

>100_bases
TGATTATCTGACGATGGGGGCACCTCACGACTCCCCGCTTGGGGTTGCCGCTACCACCTTCCGTGCATGGCGTCAGAGAA
GCTCATGTTCGCTCAGTCCG

Product: sensory box histidine kinase/response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 486; Mature: 485

Protein sequence:

>486_residues
MPPTSALILNVNDDAASRYVTSRVLGLAGFRVVDAASGMEALALVTEDTDLVILDVRLPDTSGLEVCRRLKETPRTQGVL
VLHLSAQAVGPGDRAQGLEHGADGYLVAPVDPEELVAQVHALLRLRQAEREVKALSREVVHQRQLLELAISCAADPIALY
DEAGRVLSANQSLYASRGSHAVHAPGRTLDEMQAADGALTPYLEQVRVALRTGQVQRGTMVLGSDRGPRYFDYVLSPALG
AGGEVLAVMSSLRDVTESRSAEEFREQFIGMLGHDLRNPLNALSMSAQQLRRKGGLDERQGMLTERILTSAERMDRMIRQ
LLDFARSRLGGGIPVVRSSCDVFEVVRRTVDELRASHPGRVVELESKGDGLGKWDFDRLEQAVGNLVANALKYSPAESTV
RVGAEGSEREVVLRVHNRGTPIPAEDLPHVFGAWRRGRRAASDAGAPSGLGLGLDITRQIVRAHDGDAQVASSATEGTTF
LIRLPR

Sequences:

>Translated_486_residues
MPPTSALILNVNDDAASRYVTSRVLGLAGFRVVDAASGMEALALVTEDTDLVILDVRLPDTSGLEVCRRLKETPRTQGVL
VLHLSAQAVGPGDRAQGLEHGADGYLVAPVDPEELVAQVHALLRLRQAEREVKALSREVVHQRQLLELAISCAADPIALY
DEAGRVLSANQSLYASRGSHAVHAPGRTLDEMQAADGALTPYLEQVRVALRTGQVQRGTMVLGSDRGPRYFDYVLSPALG
AGGEVLAVMSSLRDVTESRSAEEFREQFIGMLGHDLRNPLNALSMSAQQLRRKGGLDERQGMLTERILTSAERMDRMIRQ
LLDFARSRLGGGIPVVRSSCDVFEVVRRTVDELRASHPGRVVELESKGDGLGKWDFDRLEQAVGNLVANALKYSPAESTV
RVGAEGSEREVVLRVHNRGTPIPAEDLPHVFGAWRRGRRAASDAGAPSGLGLGLDITRQIVRAHDGDAQVASSATEGTTF
LIRLPR
>Mature_485_residues
PPTSALILNVNDDAASRYVTSRVLGLAGFRVVDAASGMEALALVTEDTDLVILDVRLPDTSGLEVCRRLKETPRTQGVLV
LHLSAQAVGPGDRAQGLEHGADGYLVAPVDPEELVAQVHALLRLRQAEREVKALSREVVHQRQLLELAISCAADPIALYD
EAGRVLSANQSLYASRGSHAVHAPGRTLDEMQAADGALTPYLEQVRVALRTGQVQRGTMVLGSDRGPRYFDYVLSPALGA
GGEVLAVMSSLRDVTESRSAEEFREQFIGMLGHDLRNPLNALSMSAQQLRRKGGLDERQGMLTERILTSAERMDRMIRQL
LDFARSRLGGGIPVVRSSCDVFEVVRRTVDELRASHPGRVVELESKGDGLGKWDFDRLEQAVGNLVANALKYSPAESTVR
VGAEGSEREVVLRVHNRGTPIPAEDLPHVFGAWRRGRRAASDAGAPSGLGLGLDITRQIVRAHDGDAQVASSATEGTTFL
IRLPR

Specific function: Member of the two-component regulatory system resD/resE involved in the global regulation of aerobic and anaerobic respiration. Probably phosphorylates resD [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1786783, Length=223, Percent_Identity=30.9417040358744, Blast_Score=82, Evalue=1e-16,
Organism=Escherichia coli, GI1790861, Length=258, Percent_Identity=27.5193798449612, Blast_Score=76, Evalue=6e-15,
Organism=Escherichia coli, GI1789809, Length=132, Percent_Identity=37.8787878787879, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1786599, Length=118, Percent_Identity=38.135593220339, Blast_Score=72, Evalue=1e-13,
Organism=Escherichia coli, GI1788549, Length=372, Percent_Identity=25, Blast_Score=68, Evalue=1e-12,
Organism=Escherichia coli, GI1789149, Length=246, Percent_Identity=28.0487804878049, Blast_Score=68, Evalue=1e-12,
Organism=Escherichia coli, GI1786784, Length=119, Percent_Identity=38.655462184874, Blast_Score=66, Evalue=4e-12,
Organism=Escherichia coli, GI87082128, Length=229, Percent_Identity=25.3275109170306, Blast_Score=65, Evalue=7e-12,
Organism=Escherichia coli, GI1790436, Length=217, Percent_Identity=24.8847926267281, Blast_Score=65, Evalue=8e-12,
Organism=Escherichia coli, GI1786912, Length=275, Percent_Identity=25.8181818181818, Blast_Score=65, Evalue=1e-11,
Organism=Escherichia coli, GI1786600, Length=241, Percent_Identity=26.5560165975104, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI1789808, Length=217, Percent_Identity=27.1889400921659, Blast_Score=62, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR000014
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 52594; Mature: 52463

Theoretical pI: Translated: 6.45; Mature: 6.45

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPPTSALILNVNDDAASRYVTSRVLGLAGFRVVDAASGMEALALVTEDTDLVILDVRLPD
CCCCCEEEEECCCHHHHHHHHHHHHHHHCHHHHHHHCCCEEEEEEECCCCEEEEEEECCC
TSGLEVCRRLKETPRTQGVLVLHLSAQAVGPGDRAQGLEHGADGYLVAPVDPEELVAQVH
CCHHHHHHHHHHCCCCCCEEEEEEECCCCCCCHHHHHHCCCCCCEEECCCCHHHHHHHHH
ALLRLRQAEREVKALSREVVHQRQLLELAISCAADPIALYDEAGRVLSANQSLYASRGSH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCEEECCCHHHHCCCCC
AVHAPGRTLDEMQAADGALTPYLEQVRVALRTGQVQRGTMVLGSDRGPRYFDYVLSPALG
EEECCCCCHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCEEEEECCCCCHHHHHHHHHCCC
AGGEVLAVMSSLRDVTESRSAEEFREQFIGMLGHDLRNPLNALSMSAQQLRRKGGLDERQ
CCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHH
GMLTERILTSAERMDRMIRQLLDFARSRLGGGIPVVRSSCDVFEVVRRTVDELRASHPGR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCHHHHHHHHHHHHHHCCCCCC
VVELESKGDGLGKWDFDRLEQAVGNLVANALKYSPAESTVRVGAEGSEREVVLRVHNRGT
EEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCEEECCCCCCCEEEEEEECCCC
PIPAEDLPHVFGAWRRGRRAASDAGAPSGLGLGLDITRQIVRAHDGDAQVASSATEGTTF
CCCHHHHHHHHHHHHHCCHHCCCCCCCCCCCCCHHHHHHHHHHCCCCHHHHCCCCCCCEE
LIRLPR
EEECCC
>Mature Secondary Structure 
PPTSALILNVNDDAASRYVTSRVLGLAGFRVVDAASGMEALALVTEDTDLVILDVRLPD
CCCCEEEEECCCHHHHHHHHHHHHHHHCHHHHHHHCCCEEEEEEECCCCEEEEEEECCC
TSGLEVCRRLKETPRTQGVLVLHLSAQAVGPGDRAQGLEHGADGYLVAPVDPEELVAQVH
CCHHHHHHHHHHCCCCCCEEEEEEECCCCCCCHHHHHHCCCCCCEEECCCCHHHHHHHHH
ALLRLRQAEREVKALSREVVHQRQLLELAISCAADPIALYDEAGRVLSANQSLYASRGSH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCEEECCCHHHHCCCCC
AVHAPGRTLDEMQAADGALTPYLEQVRVALRTGQVQRGTMVLGSDRGPRYFDYVLSPALG
EEECCCCCHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCEEEEECCCCCHHHHHHHHHCCC
AGGEVLAVMSSLRDVTESRSAEEFREQFIGMLGHDLRNPLNALSMSAQQLRRKGGLDERQ
CCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHH
GMLTERILTSAERMDRMIRQLLDFARSRLGGGIPVVRSSCDVFEVVRRTVDELRASHPGR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCHHHHHHHHHHHHHHCCCCCC
VVELESKGDGLGKWDFDRLEQAVGNLVANALKYSPAESTVRVGAEGSEREVVLRVHNRGT
EEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCEEECCCCCCCEEEEEEECCCC
PIPAEDLPHVFGAWRRGRRAASDAGAPSGLGLGLDITRQIVRAHDGDAQVASSATEGTTF
CCCHHHHHHHHHHHHHCCHHCCCCCCCCCCCCCHHHHHHHHHHCCCCHHHHCCCCCCCEE
LIRLPR
EEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7934829; 9384377; 8631715 [H]