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The map label for this gene is atoC [H]

Identifier: 108757900

GI number: 108757900

Start: 1035207

End: 1037030

Strand: Reverse

Name: atoC [H]

Synonym: MXAN_0907

Alternate gene names: 108757900

Gene position: 1037030-1035207 (Counterclockwise)

Preceding gene: 108759923

Following gene: 108759185

Centisome position: 11.35

GC content: 72.42

Gene sequence:

>1824_bases
ATGGCCCATTCACAGCCCAGTGCCCGCGACACGCGCCCTCTTGGGAGCGCGCCGGAATCCTCAGACTCCGGCGCCTCGTA
TCTCCTGGTGTTGGAGGGAGACTCGACGTCTCGGTTCGCCCTTCCCGCCGAAGGCGTGGTGCTGGTGGGCCGCGACGAAC
AGGCCGACCTGTGCCTGCGCGACGACAGCGTGTCACGCCGCCATGCGCGTCTGGTGTTGACGGAGGAAGGCGCGCGTCTG
GTGGACCTGGGCAGCCACAACGGCACCACCCTCAACGGCCGCCCCGTGGACACCGCACAGCCCCTGCTGTCCGGTGACGT
GGTGTCCTTTGGCGCGGTGGTCGCGGTGGTGCGCACGCGTGCACGCGCCGCGCCCGCGCACGCCCCGCTCCAGGCGGAAC
GGCTGATGGCGCGGCTGCGAGAGGAAGCGGAACGCGCCTTGCGGTATGGCCGGCCGCTCACCGCACTGGTGCTCGCGCTG
CCGCAGCAGGGCTGCGTGGGACACGAAGCCGCGGAGGCCTTGCTGGCGGCGGAGGCGGGCCCCGCGGAAGCCGCGGGCTG
GCTGGACAGCTCTCACCTGCTGTGGATGATGCCCGAGGTCTCCGGAGAGCCGGGCGAGGATGGCCTGGGTGAGCGCGTCG
GTGCGCTGCTGGCTGCGTGTCCCCAGGGGCGCCTGGGCATCGCGACCTGTCCTTCGGACGGCTGCGACGCGGAGTCCCTG
GTGGCGGCGGCGCGTGCAGCGGCCCGGACCGCGGTGTCCGGTGCGTGGGCTCCCGCGGCTGAAGGCATCACCCGCCTGAC
GTTGGCGGACCGCACCGTGCTGGTCGCGGACCCCGCCATGGCGCAGCTCTTCACGTTGCTGCGCAGGCTGGCGGCCAGCG
AGCTGCCCGTGCTGGTGTGCGGTGAAACGGGTGTGGGCAAGGAGAACGCCGCCTTCGCCGTGCACCACTGGTCTCCGCGC
TCGGACAAGCCCTTCATCGCCATCAACTGCGCGGCCCTGCCGGAGGGGCTGGTGGAGAGCGAGCTCTTCGGCCATGAGCG
CGGCGCCTTCACGGGGGCCAACACCACACGCGTGGGCCTGTTGGAGAGCGCCCAGGGCGGCACCGTCTTCCTGGACGAGG
TGGGCGAGCTGCCCCCCTCCGCACAGGCCAAGTTGCTGCGCGCGTTGGAGGTCCGCCGCATCACCCGCGTGGGCGACGTG
CGGGAGCGCCCCATCGACTTGCGCGTGGTGGCCGCCACGCACCGGGACCTGGAAGCGGAGGTGGCTGCGGGGCGGTTCCG
GGAGGACTTGTACTTCCGGCTCGGCGCGGCGACGGTGCTGCTGCCACCGCTGCGAGAGCGCCCGCGCGAGGTGCCGCTCC
TGGCGCGCGACTTCCTCGCCCGGGCATGCCAGTCGCTGGGCCGTGAGGAGATGGAGCTGTCCGCGGGCACGCTGTACGCC
CTGTCCCGCCATGCGTGGCCCGGCAACGTGCGCGAGCTGCGCAACCTGATGGACTACGCGGCGGCCGCCGTGCCGGAGAA
CGTGGTGGAGCCGCACCACCTTCCCTCGCGCCTGCAGCCTCGTGGCGCCAGCGCGCCCGCGCAGGACCTGGGGCCTCCTC
CCGCGGTGGCCGAACGGGTGTCGCCCCAGAAGACGCGGGTTCCCCTGGCCCAGGAGATTCGAGACCTGGAGCGCCGCCGC
ATGCAGGAGGCGCTCGATGAGGCAGAGGGCGTCCAGACTCGCGCGGCGGCGATGATTGGCATGCCCATCCGGACCTTCTC
GTTCAAGCTGAAGCAGCTTGGACTGCAACCCCGCACCTCCCGCAAGGGGCCGCCCATCGGATGA

Upstream 100 bases:

>100_bases
CATGAGCCACCCAGACGTGTGGAATCCGAGCCGGCGCATGTCCGGGCGGGCCCCCGGTTGCCCGGTCCAGTGTGGGCGTG
ACAGCATTCTCAGGCCCGAC

Downstream 100 bases:

>100_bases
AATCCTCCTCCGGGCGATTGGATCCCCCCGCGGAGTTCGAGGAGTACCGGCTGCTGCGCCCCCTGGGGCACGGCGCCATG
GGACAGGTGTTCCTGGCGCA

Product: sigma-54 dependent trancsriptional regulator

Products: NA

Alternate protein names: Ornithine decarboxylase antizyme; Ornithine/arginine decarboxylase inhibitor [H]

Number of amino acids: Translated: 607; Mature: 606

Protein sequence:

>607_residues
MAHSQPSARDTRPLGSAPESSDSGASYLLVLEGDSTSRFALPAEGVVLVGRDEQADLCLRDDSVSRRHARLVLTEEGARL
VDLGSHNGTTLNGRPVDTAQPLLSGDVVSFGAVVAVVRTRARAAPAHAPLQAERLMARLREEAERALRYGRPLTALVLAL
PQQGCVGHEAAEALLAAEAGPAEAAGWLDSSHLLWMMPEVSGEPGEDGLGERVGALLAACPQGRLGIATCPSDGCDAESL
VAAARAAARTAVSGAWAPAAEGITRLTLADRTVLVADPAMAQLFTLLRRLAASELPVLVCGETGVGKENAAFAVHHWSPR
SDKPFIAINCAALPEGLVESELFGHERGAFTGANTTRVGLLESAQGGTVFLDEVGELPPSAQAKLLRALEVRRITRVGDV
RERPIDLRVVAATHRDLEAEVAAGRFREDLYFRLGAATVLLPPLRERPREVPLLARDFLARACQSLGREEMELSAGTLYA
LSRHAWPGNVRELRNLMDYAAAAVPENVVEPHHLPSRLQPRGASAPAQDLGPPPAVAERVSPQKTRVPLAQEIRDLERRR
MQEALDEAEGVQTRAAAMIGMPIRTFSFKLKQLGLQPRTSRKGPPIG

Sequences:

>Translated_607_residues
MAHSQPSARDTRPLGSAPESSDSGASYLLVLEGDSTSRFALPAEGVVLVGRDEQADLCLRDDSVSRRHARLVLTEEGARL
VDLGSHNGTTLNGRPVDTAQPLLSGDVVSFGAVVAVVRTRARAAPAHAPLQAERLMARLREEAERALRYGRPLTALVLAL
PQQGCVGHEAAEALLAAEAGPAEAAGWLDSSHLLWMMPEVSGEPGEDGLGERVGALLAACPQGRLGIATCPSDGCDAESL
VAAARAAARTAVSGAWAPAAEGITRLTLADRTVLVADPAMAQLFTLLRRLAASELPVLVCGETGVGKENAAFAVHHWSPR
SDKPFIAINCAALPEGLVESELFGHERGAFTGANTTRVGLLESAQGGTVFLDEVGELPPSAQAKLLRALEVRRITRVGDV
RERPIDLRVVAATHRDLEAEVAAGRFREDLYFRLGAATVLLPPLRERPREVPLLARDFLARACQSLGREEMELSAGTLYA
LSRHAWPGNVRELRNLMDYAAAAVPENVVEPHHLPSRLQPRGASAPAQDLGPPPAVAERVSPQKTRVPLAQEIRDLERRR
MQEALDEAEGVQTRAAAMIGMPIRTFSFKLKQLGLQPRTSRKGPPIG
>Mature_606_residues
AHSQPSARDTRPLGSAPESSDSGASYLLVLEGDSTSRFALPAEGVVLVGRDEQADLCLRDDSVSRRHARLVLTEEGARLV
DLGSHNGTTLNGRPVDTAQPLLSGDVVSFGAVVAVVRTRARAAPAHAPLQAERLMARLREEAERALRYGRPLTALVLALP
QQGCVGHEAAEALLAAEAGPAEAAGWLDSSHLLWMMPEVSGEPGEDGLGERVGALLAACPQGRLGIATCPSDGCDAESLV
AAARAAARTAVSGAWAPAAEGITRLTLADRTVLVADPAMAQLFTLLRRLAASELPVLVCGETGVGKENAAFAVHHWSPRS
DKPFIAINCAALPEGLVESELFGHERGAFTGANTTRVGLLESAQGGTVFLDEVGELPPSAQAKLLRALEVRRITRVGDVR
ERPIDLRVVAATHRDLEAEVAAGRFREDLYFRLGAATVLLPPLRERPREVPLLARDFLARACQSLGREEMELSAGTLYAL
SRHAWPGNVRELRNLMDYAAAAVPENVVEPHHLPSRLQPRGASAPAQDLGPPPAVAERVSPQKTRVPLAQEIRDLERRRM
QEALDEAEGVQTRAAAMIGMPIRTFSFKLKQLGLQPRTSRKGPPIG

Specific function: Member of the two-component regulatory system AtoS/AtoC involved in the transcriptional regulation of the ato genes for acetoacetate metabolism. Also an inhibitor of polyamine biosynthesis [H]

COG id: COG2204

COG function: function code T; Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 sigma-54 factor interaction domain [H]

Homologues:

Organism=Escherichia coli, GI1788550, Length=325, Percent_Identity=41.2307692307692, Blast_Score=254, Evalue=2e-68,
Organism=Escherichia coli, GI1790299, Length=325, Percent_Identity=42.7692307692308, Blast_Score=243, Evalue=2e-65,
Organism=Escherichia coli, GI87082117, Length=329, Percent_Identity=40.7294832826748, Blast_Score=228, Evalue=1e-60,
Organism=Escherichia coli, GI1790437, Length=313, Percent_Identity=39.9361022364217, Blast_Score=222, Evalue=4e-59,
Organism=Escherichia coli, GI1789233, Length=360, Percent_Identity=38.3333333333333, Blast_Score=222, Evalue=5e-59,
Organism=Escherichia coli, GI1788905, Length=293, Percent_Identity=41.9795221843003, Blast_Score=220, Evalue=2e-58,
Organism=Escherichia coli, GI1789087, Length=323, Percent_Identity=39.6284829721362, Blast_Score=217, Evalue=2e-57,
Organism=Escherichia coli, GI87082152, Length=325, Percent_Identity=41.2307692307692, Blast_Score=208, Evalue=8e-55,
Organism=Escherichia coli, GI1786524, Length=347, Percent_Identity=38.6167146974063, Blast_Score=192, Evalue=4e-50,
Organism=Escherichia coli, GI1787583, Length=223, Percent_Identity=43.9461883408072, Blast_Score=189, Evalue=6e-49,
Organism=Escherichia coli, GI87081872, Length=307, Percent_Identity=37.785016286645, Blast_Score=174, Evalue=1e-44,
Organism=Escherichia coli, GI87081858, Length=319, Percent_Identity=30.7210031347962, Blast_Score=132, Evalue=7e-32,
Organism=Escherichia coli, GI1789828, Length=232, Percent_Identity=38.3620689655172, Blast_Score=128, Evalue=9e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR011006
- InterPro:   IPR020441
- InterPro:   IPR009057
- InterPro:   IPR002197
- InterPro:   IPR002078
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02954 HTH_8; PF00072 Response_reg; PF00158 Sigma54_activat [H]

EC number: NA

Molecular weight: Translated: 64767; Mature: 64635

Theoretical pI: Translated: 6.46; Mature: 6.46

Prosite motif: PS50006 FHA_DOMAIN ; PS00676 SIGMA54_INTERACT_2 ; PS00688 SIGMA54_INTERACT_3 ; PS50045 SIGMA54_INTERACT_4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAHSQPSARDTRPLGSAPESSDSGASYLLVLEGDSTSRFALPAEGVVLVGRDEQADLCLR
CCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEECCCCCEEECCCCCEEEEECCCCCCEEEC
DDSVSRRHARLVLTEEGARLVDLGSHNGTTLNGRPVDTAQPLLSGDVVSFGAVVAVVRTR
CCCCCCCEEEEEEECCCCEEEEECCCCCCCCCCCCCCHHHHHHCCCHHHHHHHHHHHHHH
ARAAPAHAPLQAERLMARLREEAERALRYGRPLTALVLALPQQGCVGHEAAEALLAAEAG
HHCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCCCCHHHHHHHHHHCCC
PAEAAGWLDSSHLLWMMPEVSGEPGEDGLGERVGALLAACPQGRLGIATCPSDGCDAESL
CCHHHCCCCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHCCCCCEEEEECCCCCCCHHHH
VAAARAAARTAVSGAWAPAAEGITRLTLADRTVLVADPAMAQLFTLLRRLAASELPVLVC
HHHHHHHHHHHHCCCCCHHHCCCEEEEECCCEEEEECHHHHHHHHHHHHHHHCCCCEEEE
GETGVGKENAAFAVHHWSPRSDKPFIAINCAALPEGLVESELFGHERGAFTGANTTRVGL
CCCCCCCCCCEEEEEECCCCCCCCEEEEEHHHCCCHHHHHHHHCCCCCCCCCCCCEEEEE
LESAQGGTVFLDEVGELPPSAQAKLLRALEVRRITRVGDVRERPIDLRVVAATHRDLEAE
EECCCCCEEEEHHHCCCCCHHHHHHHHHHHHHHHHHHCCHHCCCCEEEEEEECCCCHHHH
VAAGRFREDLYFRLGAATVLLPPLRERPREVPLLARDFLARACQSLGREEMELSAGTLYA
HHHHHHHHHHHHHHCCHHEECCCHHHCCCCCCHHHHHHHHHHHHHHCHHHHHHCCCHHHH
LSRHAWPGNVRELRNLMDYAAAAVPENVVEPHHLPSRLQPRGASAPAQDLGPPPAVAERV
HHCCCCCCCHHHHHHHHHHHHHHCCHHHCCCCCCCCCCCCCCCCCCHHHCCCCCHHHHCC
SPQKTRVPLAQEIRDLERRRMQEALDEAEGVQTRAAAMIGMPIRTFSFKLKQLGLQPRTS
CCCHHCCCHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHCCCHHHHHHHHHHCCCCCCCC
RKGPPIG
CCCCCCC
>Mature Secondary Structure 
AHSQPSARDTRPLGSAPESSDSGASYLLVLEGDSTSRFALPAEGVVLVGRDEQADLCLR
CCCCCCCCCCCCCCCCCCCCCCCCEEEEEEECCCCCEEECCCCCEEEEECCCCCCEEEC
DDSVSRRHARLVLTEEGARLVDLGSHNGTTLNGRPVDTAQPLLSGDVVSFGAVVAVVRTR
CCCCCCCEEEEEEECCCCEEEEECCCCCCCCCCCCCCHHHHHHCCCHHHHHHHHHHHHHH
ARAAPAHAPLQAERLMARLREEAERALRYGRPLTALVLALPQQGCVGHEAAEALLAAEAG
HHCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCCCCHHHHHHHHHHCCC
PAEAAGWLDSSHLLWMMPEVSGEPGEDGLGERVGALLAACPQGRLGIATCPSDGCDAESL
CCHHHCCCCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHCCCCCEEEEECCCCCCCHHHH
VAAARAAARTAVSGAWAPAAEGITRLTLADRTVLVADPAMAQLFTLLRRLAASELPVLVC
HHHHHHHHHHHHCCCCCHHHCCCEEEEECCCEEEEECHHHHHHHHHHHHHHHCCCCEEEE
GETGVGKENAAFAVHHWSPRSDKPFIAINCAALPEGLVESELFGHERGAFTGANTTRVGL
CCCCCCCCCCEEEEEECCCCCCCCEEEEEHHHCCCHHHHHHHHCCCCCCCCCCCCEEEEE
LESAQGGTVFLDEVGELPPSAQAKLLRALEVRRITRVGDVRERPIDLRVVAATHRDLEAE
EECCCCCEEEEHHHCCCCCHHHHHHHHHHHHHHHHHHCCHHCCCCEEEEEEECCCCHHHH
VAAGRFREDLYFRLGAATVLLPPLRERPREVPLLARDFLARACQSLGREEMELSAGTLYA
HHHHHHHHHHHHHHCCHHEECCCHHHCCCCCCHHHHHHHHHHHHHHCHHHHHHCCCHHHH
LSRHAWPGNVRELRNLMDYAAAAVPENVVEPHHLPSRLQPRGASAPAQDLGPPPAVAERV
HHCCCCCCCHHHHHHHHHHHHHHCCHHHCCCCCCCCCCCCCCCCCCHHHCCCCCHHHHCC
SPQKTRVPLAQEIRDLERRRMQEALDEAEGVQTRAAAMIGMPIRTFSFKLKQLGLQPRTS
CCCHHCCCHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHCCCHHHHHHHHHHCCCCCCCC
RKGPPIG
CCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9097040; 9278503; 8346225 [H]