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The map label for this gene is nudG [H]

Identifier: 108757874

GI number: 108757874

Start: 4486642

End: 4487067

Strand: Direct

Name: nudG [H]

Synonym: MXAN_3769

Alternate gene names: 108757874

Gene position: 4486642-4487067 (Clockwise)

Preceding gene: 108759802

Following gene: 108762120

Centisome position: 49.09

GC content: 71.83

Gene sequence:

>426_bases
ATGGTTCCGGCTCGCAGGACGGTCCGCGTGGTGGCGGCGCTGATTCCGCGGCCGGAGGATGGACGCCAGTTCCTGGTGCA
GCAGCGGCTCCCCGGTGGAAGCCGCGCCTTGCTGTGGGAGTTCCCCGGCGGCAAGGTGGAGGCCGGGGAGACGGACGCGG
CCGCGCTGGCCCGTGAGTGCCGCGAGGAACTGGACGTGGAGCTCGCCGTGGGCCGGCGGCTCTGGGAGGGCCAGCACTCC
TATCCGGACCTGACGGTGGAGTTGGTGTTGTTCCTGGCCCGGATTGTCTCGGGCGAGCCCCGGCCCCTGGGCGCCCACGC
GCTGGCGTTCCACACGCCGGCGCAGATGCAGTCACTGCCGTTCTGCGAGGCGGACATCCCGCTCCTGGACGACCTGGTGG
CGGGAAGGTTGGGCGCGCTCGATTGA

Upstream 100 bases:

>100_bases
GTGGCATCACCGCGCCGCCCTTCGCGGCGGGCAGGCAGGTGTTCGTGCTGTCGAACAACGGCTACCTGTACTCCCTGAAC
ATGAACGGGATTGACGGGTG

Downstream 100 bases:

>100_bases
TGCTGCAGCGGACGTTCCAGCACATCCCAAATGTCGGTCCCTGGCGGGAGAAGGATCTGTGGTCCCGCGGCATCCGCACC
TGGGATGACTTTCCGGAAGC

Product: NUDIX family hydrolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 141; Mature: 141

Protein sequence:

>141_residues
MVPARRTVRVVAALIPRPEDGRQFLVQQRLPGGSRALLWEFPGGKVEAGETDAAALARECREELDVELAVGRRLWEGQHS
YPDLTVELVLFLARIVSGEPRPLGAHALAFHTPAQMQSLPFCEADIPLLDDLVAGRLGALD

Sequences:

>Translated_141_residues
MVPARRTVRVVAALIPRPEDGRQFLVQQRLPGGSRALLWEFPGGKVEAGETDAAALARECREELDVELAVGRRLWEGQHS
YPDLTVELVLFLARIVSGEPRPLGAHALAFHTPAQMQSLPFCEADIPLLDDLVAGRLGALD
>Mature_141_residues
MVPARRTVRVVAALIPRPEDGRQFLVQQRLPGGSRALLWEFPGGKVEAGETDAAALARECREELDVELAVGRRLWEGQHS
YPDLTVELVLFLARIVSGEPRPLGAHALAFHTPAQMQSLPFCEADIPLLDDLVAGRLGALD

Specific function: Specific for pyrimidine substrates. Acts on 5-methyl- dCTP, CTP and dCTP in decreasing order [H]

COG id: COG0494

COG function: function code LR; NTP pyrophosphohydrolases including oxidative damage repair enzymes

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 nudix hydrolase domain [H]

Homologues:

Organism=Escherichia coli, GI1788056, Length=131, Percent_Identity=36.6412213740458, Blast_Score=67, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020476
- InterPro:   IPR020084
- InterPro:   IPR000086
- InterPro:   IPR015797 [H]

Pfam domain/function: PF00293 NUDIX [H]

EC number: 3.6.1.-

Molecular weight: Translated: 15414; Mature: 15414

Theoretical pI: Translated: 4.97; Mature: 4.97

Prosite motif: PS00133 CARBOXYPEPT_ZN_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVPARRTVRVVAALIPRPEDGRQFLVQQRLPGGSRALLWEFPGGKVEAGETDAAALAREC
CCCCHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCEEEEEECCCCEEECCCCHHHHHHHHH
REELDVELAVGRRLWEGQHSYPDLTVELVLFLARIVSGEPRPLGAHALAFHTPAQMQSLP
HHHCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCHHEEECCCHHHHCCC
FCEADIPLLDDLVAGRLGALD
CCCCCCCHHHHHHHHHCCCCC
>Mature Secondary Structure
MVPARRTVRVVAALIPRPEDGRQFLVQQRLPGGSRALLWEFPGGKVEAGETDAAALAREC
CCCCHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCEEEEEECCCCEEECCCCHHHHHHHHH
REELDVELAVGRRLWEGQHSYPDLTVELVLFLARIVSGEPRPLGAHALAFHTPAQMQSLP
HHHCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCHHEEECCCHHHHCCC
FCEADIPLLDDLVAGRLGALD
CCCCCCCHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: Fe; Mn [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9097039; 9278503; 11053429 [H]