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The map label for this gene is pckG [H]

Identifier: 108757754

GI number: 108757754

Start: 1476079

End: 1477872

Strand: Reverse

Name: pckG [H]

Synonym: MXAN_1264

Alternate gene names: 108757754

Gene position: 1477872-1476079 (Counterclockwise)

Preceding gene: 108763382

Following gene: 108762830

Centisome position: 16.17

GC content: 66.5

Gene sequence:

>1794_bases
ATGGCTTCGACGCAAGTTGCGGCGGAGGGCCAGCAGGCCCCCACGAAAAATCCCACGCTCCTGGCCTGGGTGGCCAAGAT
GGCCGAGATGACCCAGCCGGACAGCATCGTCTGGTGTGACGGGTCCGAGGCGGAGAAGAAGCGGCTGACGGACCAGGCGG
TGAAGGAGGGCATCCTCATCCCGCTGAACCCGGAGAAGCGCCCCAACAGCTACCTCCACCGCTCCAACCCGAACGACGTG
GCGCGCGTGGAGCACCTCACGTTCATCTGCACGCCGAACAAGACGGACGCCGGCCCGACGAACAACTGGATGGAGCCCGA
GGCGGCCTACACCAAGCTGGGCAACCTGTTCACCGGGTGCATGAAGGGCCGCACCATGTACGTGGTGCCCTACGCCATGG
GCCCCATCGGCAGCCCCTTCACCAAGCTGGGCGTGGAGCTGACCGACAGCATCTACGTCGTGCTGAACATGCGCATCATG
GCGCGCATGGGGAAGCAGGCGCTGGACATGCTGGGTGACAGCGACGACTTCAACCGCGGCCTGCACAGCACCGGCGACGT
GGACCCCGACCGCCGCTACATCTGCCACTTCCCCCAGGACAACACCATCTGGAGCTTCGGCTCCGGCTACGGCGGCAACG
TGCTGCTGGGCAAGAAGTGCCTCGCGCTGCGCATCGGCAGCTACCTGGGCCGCGAGGAAGGCTGGATGGCCGAGCACATG
CTCATCCTGGGTGTCACCAGCCCCAAGGGTGAGACGACCTACGTCGCCGCCGCCTTCCCGTCCGCGTGTGGCAAGACGAA
CTTCGCGATGATGATTCCGCCCCCCGAGTACAAGGGCTGGAAGATTGAGACCGTCGGCGACGACATCGCGTGGATGCACC
CCGGCAAGGATGGCCGCCTGTACGCCATCAACCCGGAGGCCGGCTACTTCGGCGTGGTGCCCGGCACCAACTACAAGACG
AACCCCAACGCGATGGAGTCCATCGCCAAGGACACCATCTTCACCAACGTGGCGCTGACGGCGGACGGCGATGTGTGGTG
GGAGGGCAAGGACGGCGAGGTCCCCGACGAGCTCACCGACTGGCAGGGCCGCCCCTGGAAGAAGGGCAGCGCGGAGAAGG
CGGCGCACCCCAACAGCCGCTTCACCGCGCCCATGTCCAACAACCCGGCGCTGAGCCCCAAGGCCAACGATCCGACGGGC
GTGCCCATCTCCGCGCTCATCTTCGGCGGCCGCCGCTCCAACACCGTCCCACTGGTGCTCCAGGCCTTCAACTGGACCCA
CGGCGTGTTCCTGGGCGCCACCATGGGCAGCGAGACGACGGCCGCGGCCACCGGCAAGGTCGGCGTCGTGCGCCGCGACC
CCATGGCCATGCTGCCCTTCTGCGGCTACCACATGGGTGACTACCTCCAGCACTGGCTGGACATGCAGAAGCACATCGCC
CAGCTGCCGAAGATCTTCCAGGTCAACTGGTTCCGCCAGGACAAGAACGGCAAGTTCATGTGGCCGGGCTTCGGCGAGAA
CATGCGCGTGCTGGAGTGGATCGTGAACCGCGTCCACGGCCGCGTCCCCACCCAGGAGACGCTGCTGGGCTGGGTGCCCC
GCGCCGACCAGGGCCTCAACCTCAATGGCCTGGACCTGGCCTCCGACGTGGTGGCGGAAGTCACGTCCATCAAGGAGGAC
GAATGGAAGTCCGAGCTGAAGAGCCAGGAGGTCTTCTTCGAGCAGCTCGGCACCAAGGCGCCGGACGCGCTGATGCTCCA
GCGCAAGCTGCTGATGGCGCGCCTGGACCACTGA

Upstream 100 bases:

>100_bases
GTTCGGTACCAAGACGGGCGGTCGGTCACAGGTTGCATTTATGCCCCCCTTCCAGAACGTTTGGGGCCTGTCTCCAGACC
TGAACCACGAGGACGAATCC

Downstream 100 bases:

>100_bases
GTCCCCGCCGGCCTGTAGCAGCCTGAAATCCCGGGGCCGCCTCCCGCTCGCACCGAGCGCGGGGGCGGCCTCTCCATTTT
TCACAGGAAGTAAAAGTCAG

Product: phosphoenolpyruvate carboxykinase

Products: NA

Alternate protein names: PEP carboxykinase; PEPCK; Phosphoenolpyruvate carboxylase [H]

Number of amino acids: Translated: 597; Mature: 596

Protein sequence:

>597_residues
MASTQVAAEGQQAPTKNPTLLAWVAKMAEMTQPDSIVWCDGSEAEKKRLTDQAVKEGILIPLNPEKRPNSYLHRSNPNDV
ARVEHLTFICTPNKTDAGPTNNWMEPEAAYTKLGNLFTGCMKGRTMYVVPYAMGPIGSPFTKLGVELTDSIYVVLNMRIM
ARMGKQALDMLGDSDDFNRGLHSTGDVDPDRRYICHFPQDNTIWSFGSGYGGNVLLGKKCLALRIGSYLGREEGWMAEHM
LILGVTSPKGETTYVAAAFPSACGKTNFAMMIPPPEYKGWKIETVGDDIAWMHPGKDGRLYAINPEAGYFGVVPGTNYKT
NPNAMESIAKDTIFTNVALTADGDVWWEGKDGEVPDELTDWQGRPWKKGSAEKAAHPNSRFTAPMSNNPALSPKANDPTG
VPISALIFGGRRSNTVPLVLQAFNWTHGVFLGATMGSETTAAATGKVGVVRRDPMAMLPFCGYHMGDYLQHWLDMQKHIA
QLPKIFQVNWFRQDKNGKFMWPGFGENMRVLEWIVNRVHGRVPTQETLLGWVPRADQGLNLNGLDLASDVVAEVTSIKED
EWKSELKSQEVFFEQLGTKAPDALMLQRKLLMARLDH

Sequences:

>Translated_597_residues
MASTQVAAEGQQAPTKNPTLLAWVAKMAEMTQPDSIVWCDGSEAEKKRLTDQAVKEGILIPLNPEKRPNSYLHRSNPNDV
ARVEHLTFICTPNKTDAGPTNNWMEPEAAYTKLGNLFTGCMKGRTMYVVPYAMGPIGSPFTKLGVELTDSIYVVLNMRIM
ARMGKQALDMLGDSDDFNRGLHSTGDVDPDRRYICHFPQDNTIWSFGSGYGGNVLLGKKCLALRIGSYLGREEGWMAEHM
LILGVTSPKGETTYVAAAFPSACGKTNFAMMIPPPEYKGWKIETVGDDIAWMHPGKDGRLYAINPEAGYFGVVPGTNYKT
NPNAMESIAKDTIFTNVALTADGDVWWEGKDGEVPDELTDWQGRPWKKGSAEKAAHPNSRFTAPMSNNPALSPKANDPTG
VPISALIFGGRRSNTVPLVLQAFNWTHGVFLGATMGSETTAAATGKVGVVRRDPMAMLPFCGYHMGDYLQHWLDMQKHIA
QLPKIFQVNWFRQDKNGKFMWPGFGENMRVLEWIVNRVHGRVPTQETLLGWVPRADQGLNLNGLDLASDVVAEVTSIKED
EWKSELKSQEVFFEQLGTKAPDALMLQRKLLMARLDH
>Mature_596_residues
ASTQVAAEGQQAPTKNPTLLAWVAKMAEMTQPDSIVWCDGSEAEKKRLTDQAVKEGILIPLNPEKRPNSYLHRSNPNDVA
RVEHLTFICTPNKTDAGPTNNWMEPEAAYTKLGNLFTGCMKGRTMYVVPYAMGPIGSPFTKLGVELTDSIYVVLNMRIMA
RMGKQALDMLGDSDDFNRGLHSTGDVDPDRRYICHFPQDNTIWSFGSGYGGNVLLGKKCLALRIGSYLGREEGWMAEHML
ILGVTSPKGETTYVAAAFPSACGKTNFAMMIPPPEYKGWKIETVGDDIAWMHPGKDGRLYAINPEAGYFGVVPGTNYKTN
PNAMESIAKDTIFTNVALTADGDVWWEGKDGEVPDELTDWQGRPWKKGSAEKAAHPNSRFTAPMSNNPALSPKANDPTGV
PISALIFGGRRSNTVPLVLQAFNWTHGVFLGATMGSETTAAATGKVGVVRRDPMAMLPFCGYHMGDYLQHWLDMQKHIAQ
LPKIFQVNWFRQDKNGKFMWPGFGENMRVLEWIVNRVHGRVPTQETLLGWVPRADQGLNLNGLDLASDVVAEVTSIKEDE
WKSELKSQEVFFEQLGTKAPDALMLQRKLLMARLDH

Specific function: Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle [H]

COG id: COG1274

COG function: function code C; Phosphoenolpyruvate carboxykinase (GTP)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the phosphoenolpyruvate carboxykinase [GTP] family [H]

Homologues:

Organism=Homo sapiens, GI66346721, Length=599, Percent_Identity=49.9165275459099, Blast_Score=571, Evalue=1e-163,
Organism=Homo sapiens, GI187281517, Length=592, Percent_Identity=50.6756756756757, Blast_Score=570, Evalue=1e-162,
Organism=Homo sapiens, GI66346723, Length=381, Percent_Identity=51.4435695538058, Blast_Score=367, Evalue=1e-101,
Organism=Caenorhabditis elegans, GI17555492, Length=616, Percent_Identity=48.538961038961, Blast_Score=562, Evalue=1e-160,
Organism=Caenorhabditis elegans, GI71989645, Length=589, Percent_Identity=48.8964346349745, Blast_Score=556, Evalue=1e-158,
Organism=Caenorhabditis elegans, GI71989658, Length=589, Percent_Identity=48.8964346349745, Blast_Score=555, Evalue=1e-158,
Organism=Caenorhabditis elegans, GI32564411, Length=538, Percent_Identity=52.0446096654275, Blast_Score=549, Evalue=1e-156,
Organism=Caenorhabditis elegans, GI71989653, Length=580, Percent_Identity=49.1379310344828, Blast_Score=547, Evalue=1e-156,
Organism=Caenorhabditis elegans, GI32564407, Length=522, Percent_Identity=50.9578544061303, Blast_Score=511, Evalue=1e-145,
Organism=Caenorhabditis elegans, GI71989649, Length=490, Percent_Identity=50.6122448979592, Blast_Score=481, Evalue=1e-136,
Organism=Caenorhabditis elegans, GI32564409, Length=368, Percent_Identity=49.4565217391304, Blast_Score=346, Evalue=2e-95,
Organism=Caenorhabditis elegans, GI17540956, Length=641, Percent_Identity=24.4929797191888, Blast_Score=160, Evalue=2e-39,
Organism=Drosophila melanogaster, GI24655085, Length=600, Percent_Identity=51, Blast_Score=598, Evalue=1e-171,
Organism=Drosophila melanogaster, GI24655082, Length=604, Percent_Identity=49.0066225165563, Blast_Score=564, Evalue=1e-161,
Organism=Drosophila melanogaster, GI161077226, Length=567, Percent_Identity=49.9118165784832, Blast_Score=537, Evalue=1e-153,
Organism=Drosophila melanogaster, GI24655088, Length=496, Percent_Identity=54.0322580645161, Blast_Score=536, Evalue=1e-152,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018091
- InterPro:   IPR013035
- InterPro:   IPR008209
- InterPro:   IPR008210 [H]

Pfam domain/function: PF00821 PEPCK [H]

EC number: =4.1.1.32 [H]

Molecular weight: Translated: 66104; Mature: 65973

Theoretical pI: Translated: 6.70; Mature: 6.70

Prosite motif: PS00505 PEPCK_GTP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
4.5 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
4.4 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MASTQVAAEGQQAPTKNPTLLAWVAKMAEMTQPDSIVWCDGSEAEKKRLTDQAVKEGILI
CCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCEEEECCCHHHHHHHHHHHHHCCEEE
PLNPEKRPNSYLHRSNPNDVARVEHLTFICTPNKTDAGPTNNWMEPEAAYTKLGNLFTGC
ECCCCCCCCCCCCCCCCCHHEEEEEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHH
MKGRTMYVVPYAMGPIGSPFTKLGVELTDSIYVVLNMRIMARMGKQALDMLGDSDDFNRG
HCCCEEEEEEEECCCCCCCHHHHCHHHCCCEEEEHHHHHHHHHHHHHHHHCCCCCHHHCC
LHSTGDVDPDRRYICHFPQDNTIWSFGSGYGGNVLLGKKCLALRIGSYLGREEGWMAEHM
CCCCCCCCCCCCEEEECCCCCCEEECCCCCCCCEEECCHHHHHHHHHHHCCCCCCCCCEE
LILGVTSPKGETTYVAAAFPSACGKTNFAMMIPPPEYKGWKIETVGDDIAWMHPGKDGRL
EEEEECCCCCCEEEEEEECCCCCCCCCEEEEECCCCCCCEEEEECCCCEEEECCCCCCEE
YAINPEAGYFGVVPGTNYKTNPNAMESIAKDTIFTNVALTADGDVWWEGKDGEVPDELTD
EEECCCCCEEECCCCCCCCCCCHHHHHHHHHHHEEEEEEEECCCEEECCCCCCCCHHHHC
WQGRPWKKGSAEKAAHPNSRFTAPMSNNPALSPKANDPTGVPISALIFGGRRSNTVPLVL
CCCCCCCCCCCCCCCCCCCCEECCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCCEEEE
QAFNWTHGVFLGATMGSETTAAATGKVGVVRRDPMAMLPFCGYHMGDYLQHWLDMQKHIA
EECCCCCCEEEEEECCCCCCCCCCCCEEEEECCCHHHCCHHHHHHHHHHHHHHHHHHHHH
QLPKIFQVNWFRQDKNGKFMWPGFGENMRVLEWIVNRVHGRVPTQETLLGWVPRADQGLN
HCCCEEEEEEEEECCCCCEECCCCCCCHHHHHHHHHHHCCCCCCHHHHHCCCCCCCCCCC
LNGLDLASDVVAEVTSIKEDEWKSELKSQEVFFEQLGTKAPDALMLQRKLLMARLDH
CCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
ASTQVAAEGQQAPTKNPTLLAWVAKMAEMTQPDSIVWCDGSEAEKKRLTDQAVKEGILI
CCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCEEEECCCHHHHHHHHHHHHHCCEEE
PLNPEKRPNSYLHRSNPNDVARVEHLTFICTPNKTDAGPTNNWMEPEAAYTKLGNLFTGC
ECCCCCCCCCCCCCCCCCHHEEEEEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHH
MKGRTMYVVPYAMGPIGSPFTKLGVELTDSIYVVLNMRIMARMGKQALDMLGDSDDFNRG
HCCCEEEEEEEECCCCCCCHHHHCHHHCCCEEEEHHHHHHHHHHHHHHHHCCCCCHHHCC
LHSTGDVDPDRRYICHFPQDNTIWSFGSGYGGNVLLGKKCLALRIGSYLGREEGWMAEHM
CCCCCCCCCCCCEEEECCCCCCEEECCCCCCCCEEECCHHHHHHHHHHHCCCCCCCCCEE
LILGVTSPKGETTYVAAAFPSACGKTNFAMMIPPPEYKGWKIETVGDDIAWMHPGKDGRL
EEEEECCCCCCEEEEEEECCCCCCCCCEEEEECCCCCCCEEEEECCCCEEEECCCCCCEE
YAINPEAGYFGVVPGTNYKTNPNAMESIAKDTIFTNVALTADGDVWWEGKDGEVPDELTD
EEECCCCCEEECCCCCCCCCCCHHHHHHHHHHHEEEEEEEECCCEEECCCCCCCCHHHHC
WQGRPWKKGSAEKAAHPNSRFTAPMSNNPALSPKANDPTGVPISALIFGGRRSNTVPLVL
CCCCCCCCCCCCCCCCCCCCEECCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCCEEEE
QAFNWTHGVFLGATMGSETTAAATGKVGVVRRDPMAMLPFCGYHMGDYLQHWLDMQKHIA
EECCCCCCEEEEEECCCCCCCCCCCCEEEEECCCHHHCCHHHHHHHHHHHHHHHHHHHHH
QLPKIFQVNWFRQDKNGKFMWPGFGENMRVLEWIVNRVHGRVPTQETLLGWVPRADQGLN
HCCCEEEEEEEEECCCCCEECCCCCCCHHHHHHHHHHHCCCCCCHHHHHCCCCCCCCCCC
LNGLDLASDVVAEVTSIKEDEWKSELKSQEVFFEQLGTKAPDALMLQRKLLMARLDH
CCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA