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The map label for this gene is tmk [H]

Identifier: 108757704

GI number: 108757704

Start: 3004561

End: 3006261

Strand: Reverse

Name: tmk [H]

Synonym: MXAN_2582

Alternate gene names: 108757704

Gene position: 3006261-3004561 (Counterclockwise)

Preceding gene: 108757316

Following gene: 108758954

Centisome position: 32.89

GC content: 71.96

Gene sequence:

>1701_bases
GTGTTCATCGACTTCGAGGGAATTGACGGAAGCGGCAAGACGACGCTCTCCAACCTGCTGGCCGCGAAGCTGAAGCGGCT
GGGCTACCGGGTGGCGCATGCGCGGGAGGGCGGCGAGCTGCAGGCGCCCGCGGCGCGGCGCATCCGGGAGCTGACGCGAG
ACTCCCGGCTGCTGGAGATGTCTCCACGCACGGAGTTCTTCCTCAACCTGGCGCGGGACGCCCAACAACTGGATGAAGTG
GTGGCGCCCGCGCTGTCCCGGGGCGAGGTGTGCATCACCGACCGCTACCTGTACTCACAACTGGCGCTCAGCGGTGGAGG
CCGCGGGCTGCCCATGGACGAGCTGCGACCCGCGTGCGAGCTGGCCTCGCAGGGCCTGTGGCCGGACCTGGTCATCCTGG
TGGACGTGGATCCGGACCTCGCCCGGCTGCGCAAGCGCCTGGGCAAGCTCCAAAGCAAGCGCGTCAGTGATGGGGACAGC
CGGAAGGGACTGGTGGGCGCGGGCCTGGCGGTGCGCGTGCGCGAGTCCTTCCTGGAGATGGCGCGGAAGGATCCGCAGCG
GTGGATCATCCTGGAGAACAACGACGTCCCTCTGCGCGTGTTGGAGCAGCGGCTGGTGGACGCCGTCGTCGCCCGGCTGG
AGGGGCGCGAGCAGCAGGTGCAGCGCATCGTCCCGGCGCCGGCCCGGCCACGGAATGCCAGCCCCACCACGCTCGAGAAC
CTGGAAGAGCGATTCTTCCAGACGCTGGACACCGTGGAGCAGCGCGAACCGGCGCTCGCGGTGTGGATGTTGAGCGGAAT
CCCGGGCCTGGCCGCGCACCAGAAGCGCCTGGCCTTCGCGGAGCGCTTCCCGGGCCTCACCGCGCGCGGCATGGCGGGCC
TGGCTGACGTACCGGCCATGGGCCTGCGCGAGGTGCTGGCGGACCTGGCGCCCGCGGAGGTGGCCTTCAGCCTCACGGGC
CGCATGGACTCGCGCGCGGCCATGTTGCGGCAGCGGCTGTACGCGCAGGCCCCCACGGAGGTGCTGGCGAGCCTCAAGAA
CGATGGCTCGACCCCGGCGTGGGCCCTGCGCGAGCGCGCCATGCGGGACGGGCGGCTGGCGGACGTGCTCGCGGGGCTCG
CCGGCCAGGACTGCGAGGAGTCCTGGTTGGTGCGCGAGGCGGGCATGCAGCGCAAGCTGTTCTCGGAGGTGGCGAGCAGC
CTCACCAGTGTCCCGGGGGCGCGGGCGGATGCGCTGCGCGAAGTCCTGCTGCCGCATGACCGGCTGGCGGTGCTGCGCAG
CACCCTGGGCCTGGACACACCGGTGGCCCGAGGCCTGCGAGAGGCCCTGGCGGGCAAGGCGCTGAAGCTGGTGCTCCGCT
CGCTGACGGGCCTGGACACCGAGGAAGCCTGGACGCTGCGCGAGCGCGGCGCGCCGCAAACGAAGGAGGCGCTGGATTCG
GTGGACGGCATGGATGGCACGCGGGCCTGGAAGCTGCGTGTGGACCATCTGGGCCGGTGGCCCACCACCGCGCTGTCCTC
CTTGAAGGGACTGCCCATGGGGCCGCACGCGCAGGCGCTCATCGAGCGTGTGCTGGCGGAACAGCCAGACCGGCTGCCGG
TGCTGCGCAACGCCTACGCCGTAGCGGCGACCGCACGGGCGCTCGCGCAGCAGCCCGCGCGCACGGTCCGCGTGGGCACC
TCTCCCCGAATGGAAGCCTAG

Upstream 100 bases:

>100_bases
GCTCAATCCGGGCGGCGCGCCGGCCTACAGCAAGTTCGCAGAGGGAATGGCGAAGGTCCACGCTTTCGCCGCGGATGGCG
TCGCAGGGGGATAGGGCACA

Downstream 100 bases:

>100_bases
GTCACCGCCATGGACGCATCATTCTCAGCCCTGTTCGAGGGCGCGAAAGCGGAGCTCAGCGCGCTGTCCGTCACCGCGAT
TCTGCCGCGGATGCTGGCCG

Product: putative thymidylate kinase

Products: NA

Alternate protein names: dTMP kinase [H]

Number of amino acids: Translated: 566; Mature: 566

Protein sequence:

>566_residues
MFIDFEGIDGSGKTTLSNLLAAKLKRLGYRVAHAREGGELQAPAARRIRELTRDSRLLEMSPRTEFFLNLARDAQQLDEV
VAPALSRGEVCITDRYLYSQLALSGGGRGLPMDELRPACELASQGLWPDLVILVDVDPDLARLRKRLGKLQSKRVSDGDS
RKGLVGAGLAVRVRESFLEMARKDPQRWIILENNDVPLRVLEQRLVDAVVARLEGREQQVQRIVPAPARPRNASPTTLEN
LEERFFQTLDTVEQREPALAVWMLSGIPGLAAHQKRLAFAERFPGLTARGMAGLADVPAMGLREVLADLAPAEVAFSLTG
RMDSRAAMLRQRLYAQAPTEVLASLKNDGSTPAWALRERAMRDGRLADVLAGLAGQDCEESWLVREAGMQRKLFSEVASS
LTSVPGARADALREVLLPHDRLAVLRSTLGLDTPVARGLREALAGKALKLVLRSLTGLDTEEAWTLRERGAPQTKEALDS
VDGMDGTRAWKLRVDHLGRWPTTALSSLKGLPMGPHAQALIERVLAEQPDRLPVLRNAYAVAATARALAQQPARTVRVGT
SPRMEA

Sequences:

>Translated_566_residues
MFIDFEGIDGSGKTTLSNLLAAKLKRLGYRVAHAREGGELQAPAARRIRELTRDSRLLEMSPRTEFFLNLARDAQQLDEV
VAPALSRGEVCITDRYLYSQLALSGGGRGLPMDELRPACELASQGLWPDLVILVDVDPDLARLRKRLGKLQSKRVSDGDS
RKGLVGAGLAVRVRESFLEMARKDPQRWIILENNDVPLRVLEQRLVDAVVARLEGREQQVQRIVPAPARPRNASPTTLEN
LEERFFQTLDTVEQREPALAVWMLSGIPGLAAHQKRLAFAERFPGLTARGMAGLADVPAMGLREVLADLAPAEVAFSLTG
RMDSRAAMLRQRLYAQAPTEVLASLKNDGSTPAWALRERAMRDGRLADVLAGLAGQDCEESWLVREAGMQRKLFSEVASS
LTSVPGARADALREVLLPHDRLAVLRSTLGLDTPVARGLREALAGKALKLVLRSLTGLDTEEAWTLRERGAPQTKEALDS
VDGMDGTRAWKLRVDHLGRWPTTALSSLKGLPMGPHAQALIERVLAEQPDRLPVLRNAYAVAATARALAQQPARTVRVGT
SPRMEA
>Mature_566_residues
MFIDFEGIDGSGKTTLSNLLAAKLKRLGYRVAHAREGGELQAPAARRIRELTRDSRLLEMSPRTEFFLNLARDAQQLDEV
VAPALSRGEVCITDRYLYSQLALSGGGRGLPMDELRPACELASQGLWPDLVILVDVDPDLARLRKRLGKLQSKRVSDGDS
RKGLVGAGLAVRVRESFLEMARKDPQRWIILENNDVPLRVLEQRLVDAVVARLEGREQQVQRIVPAPARPRNASPTTLEN
LEERFFQTLDTVEQREPALAVWMLSGIPGLAAHQKRLAFAERFPGLTARGMAGLADVPAMGLREVLADLAPAEVAFSLTG
RMDSRAAMLRQRLYAQAPTEVLASLKNDGSTPAWALRERAMRDGRLADVLAGLAGQDCEESWLVREAGMQRKLFSEVASS
LTSVPGARADALREVLLPHDRLAVLRSTLGLDTPVARGLREALAGKALKLVLRSLTGLDTEEAWTLRERGAPQTKEALDS
VDGMDGTRAWKLRVDHLGRWPTTALSSLKGLPMGPHAQALIERVLAEQPDRLPVLRNAYAVAATARALAQQPARTVRVGT
SPRMEA

Specific function: Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis [H]

COG id: COG0125

COG function: function code F; Thymidylate kinase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the thymidylate kinase family [H]

Homologues:

Organism=Escherichia coli, GI1787340, Length=191, Percent_Identity=29.3193717277487, Blast_Score=70, Evalue=5e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018094 [H]

Pfam domain/function: PF02223 Thymidylate_kin [H]

EC number: =2.7.4.9 [H]

Molecular weight: Translated: 62066; Mature: 62066

Theoretical pI: Translated: 10.06; Mature: 10.06

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFIDFEGIDGSGKTTLSNLLAAKLKRLGYRVAHAREGGELQAPAARRIRELTRDSRLLEM
CEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCEEEC
SPRTEFFLNLARDAQQLDEVVAPALSRGEVCITDRYLYSQLALSGGGRGLPMDELRPACE
CCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHCCCCCCCCHHHHHHHHH
LASQGLWPDLVILVDVDPDLARLRKRLGKLQSKRVSDGDSRKGLVGAGLAVRVRESFLEM
HHHCCCCCCEEEEEECCHHHHHHHHHHHHHHHHCCCCCCCCCCCHHCCHHHHHHHHHHHH
ARKDPQRWIILENNDVPLRVLEQRLVDAVVARLEGREQQVQRIVPAPARPRNASPTTLEN
HHCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCCCCCCHHHHH
LEERFFQTLDTVEQREPALAVWMLSGIPGLAAHQKRLAFAERFPGLTARGMAGLADVPAM
HHHHHHHHHHHHHHCCCCEEEHHHHCCCCHHHHHHHHHHHHHCCCCCHHCCCCCCCCCHH
GLREVLADLAPAEVAFSLTGRMDSRAAMLRQRLYAQAPTEVLASLKNDGSTPAWALRERA
HHHHHHHHCCHHHHHHHHHCCCHHHHHHHHHHHHHCCHHHHHHHHHCCCCCHHHHHHHHH
MRDGRLADVLAGLAGQDCEESWLVREAGMQRKLFSEVASSLTSVPGARADALREVLLPHD
HHCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCHH
RLAVLRSTLGLDTPVARGLREALAGKALKLVLRSLTGLDTEEAWTLRERGAPQTKEALDS
HHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCHHHHHHHH
VDGMDGTRAWKLRVDHLGRWPTTALSSLKGLPMGPHAQALIERVLAEQPDRLPVLRNAYA
HCCCCCCEEEEEEHHHCCCCCHHHHHHCCCCCCCCCHHHHHHHHHHCCCCCCCHHHHHHH
VAATARALAQQPARTVRVGTSPRMEA
HHHHHHHHHHCCCCEEECCCCCCCCC
>Mature Secondary Structure
MFIDFEGIDGSGKTTLSNLLAAKLKRLGYRVAHAREGGELQAPAARRIRELTRDSRLLEM
CEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCEEEC
SPRTEFFLNLARDAQQLDEVVAPALSRGEVCITDRYLYSQLALSGGGRGLPMDELRPACE
CCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHCCCCCCCCHHHHHHHHH
LASQGLWPDLVILVDVDPDLARLRKRLGKLQSKRVSDGDSRKGLVGAGLAVRVRESFLEM
HHHCCCCCCEEEEEECCHHHHHHHHHHHHHHHHCCCCCCCCCCCHHCCHHHHHHHHHHHH
ARKDPQRWIILENNDVPLRVLEQRLVDAVVARLEGREQQVQRIVPAPARPRNASPTTLEN
HHCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCCCCCCHHHHH
LEERFFQTLDTVEQREPALAVWMLSGIPGLAAHQKRLAFAERFPGLTARGMAGLADVPAM
HHHHHHHHHHHHHHCCCCEEEHHHHCCCCHHHHHHHHHHHHHCCCCCHHCCCCCCCCCHH
GLREVLADLAPAEVAFSLTGRMDSRAAMLRQRLYAQAPTEVLASLKNDGSTPAWALRERA
HHHHHHHHCCHHHHHHHHHCCCHHHHHHHHHHHHHCCHHHHHHHHHCCCCCHHHHHHHHH
MRDGRLADVLAGLAGQDCEESWLVREAGMQRKLFSEVASSLTSVPGARADALREVLLPHD
HHCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCHH
RLAVLRSTLGLDTPVARGLREALAGKALKLVLRSLTGLDTEEAWTLRERGAPQTKEALDS
HHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCHHHHHHHH
VDGMDGTRAWKLRVDHLGRWPTTALSSLKGLPMGPHAQALIERVLAEQPDRLPVLRNAYA
HCCCCCCEEEEEEHHHCCCCCHHHHHHCCCCCCCCCHHHHHHHHHHCCCCCCCHHHHHHH
VAATARALAQQPARTVRVGTSPRMEA
HHHHHHHHHHCCCCEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA