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The map label for this gene is degU [H]

Identifier: 108757533

GI number: 108757533

Start: 4989103

End: 4989843

Strand: Direct

Name: degU [H]

Synonym: MXAN_4072

Alternate gene names: 108757533

Gene position: 4989103-4989843 (Clockwise)

Preceding gene: 108759452

Following gene: 108760061

Centisome position: 54.59

GC content: 66.67

Gene sequence:

>741_bases
ATGACCGGAGCTCCCGTGGACGCCCCGCAGCCTCCTGATTCGCCGCCCATTCGCGTCTTCGTGGTCGAGGATCAAACGAA
GATCCTCAAGAACCAGCTCCGCCTCTTCGAGAACCACCCGGAGATGGACATCATCGGCACCGCGCTCTCCGGTGAAGCCG
CGCTGGAGGAAGTGCCCAAGCTGATGCCGGACGTGCTGCTGCTCGACCTGGGCCTGCCCCGCATGAGCGGCATCGACGTG
ACGCGCGAGGTGAAGGCGCGCTTCCCGAAGATTGAAATCCTCATCTTCACCATCTTCGACGAGGAGGACAAAGTGCTGGA
GGCCGTGAAGGCGGGCGCCTCCGGCTACCTGCTCAAGGGCGCCCCGGTGGACAAGATCATCGAGGCCATCAAGGAAGTCC
GCGCGGGCGGCACCGTCATCCAGCCCAACCTGGCCCGCCGGCTGCTCCGTCACTTCCGCGTGGAGCCCGACGCCAGCCCC
TTGATCTCACCGCCCGCCGCGCCGGAGCCGTCGGCCAGCGACCTGCCCCAGGAGCCCCTGCTCAAGCCGCTGTCGGACCG
CGAGCGCGAAATCCTCCAGCTCATCGCCAAGGGCGTCTCCAACAGCGAGGCAGCGCGCCTGCTCGACCTCAGCAAGGCCA
CCATCCGCACGCACCTGGAGCACATCTACCGGAAGCTGGAGGTCACCAACCGCGTGGAGGCCGTCACCGAAGGCATCCGC
AAGGGCCTCATCTCCGTCTGA

Upstream 100 bases:

>100_bases
ACATGCGCGAGCGCGCCATGAAGCTCGGTGGCCAGCTCATCGTGGACTCGTCACCCGGCGCTGGCGCCCAGGTGGCATTC
TCCCTTCCCTGTCGCCCGTC

Downstream 100 bases:

>100_bases
GCCGGAGCGCCGCGCTCAGCGCCCCGTGGAGACCGCCGCGCCCGGACGCTCCGCGGCGGCGGCCTCCATGACCAGGTCCG
CGTACCGGTTGACCGGGTCT

Product: LuxR family DNA-binding response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 246; Mature: 245

Protein sequence:

>246_residues
MTGAPVDAPQPPDSPPIRVFVVEDQTKILKNQLRLFENHPEMDIIGTALSGEAALEEVPKLMPDVLLLDLGLPRMSGIDV
TREVKARFPKIEILIFTIFDEEDKVLEAVKAGASGYLLKGAPVDKIIEAIKEVRAGGTVIQPNLARRLLRHFRVEPDASP
LISPPAAPEPSASDLPQEPLLKPLSDREREILQLIAKGVSNSEAARLLDLSKATIRTHLEHIYRKLEVTNRVEAVTEGIR
KGLISV

Sequences:

>Translated_246_residues
MTGAPVDAPQPPDSPPIRVFVVEDQTKILKNQLRLFENHPEMDIIGTALSGEAALEEVPKLMPDVLLLDLGLPRMSGIDV
TREVKARFPKIEILIFTIFDEEDKVLEAVKAGASGYLLKGAPVDKIIEAIKEVRAGGTVIQPNLARRLLRHFRVEPDASP
LISPPAAPEPSASDLPQEPLLKPLSDREREILQLIAKGVSNSEAARLLDLSKATIRTHLEHIYRKLEVTNRVEAVTEGIR
KGLISV
>Mature_245_residues
TGAPVDAPQPPDSPPIRVFVVEDQTKILKNQLRLFENHPEMDIIGTALSGEAALEEVPKLMPDVLLLDLGLPRMSGIDVT
REVKARFPKIEILIFTIFDEEDKVLEAVKAGASGYLLKGAPVDKIIEAIKEVRAGGTVIQPNLARRLLRHFRVEPDASPL
ISPPAAPEPSASDLPQEPLLKPLSDREREILQLIAKGVSNSEAARLLDLSKATIRTHLEHIYRKLEVTNRVEAVTEGIRK
GLISV

Specific function: Regulating factor for the production of extracellular proteases. The N-terminal region acts as an inhibitor, whereas the C-terminal region carries enhancing activity [H]

COG id: COG2197

COG function: function code TK; Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1788521, Length=223, Percent_Identity=28.6995515695067, Blast_Score=99, Evalue=4e-22,
Organism=Escherichia coli, GI1788222, Length=229, Percent_Identity=27.9475982532751, Blast_Score=97, Evalue=1e-21,
Organism=Escherichia coli, GI1787473, Length=222, Percent_Identity=28.8288288288288, Blast_Score=83, Evalue=2e-17,
Organism=Escherichia coli, GI1789937, Length=54, Percent_Identity=53.7037037037037, Blast_Score=65, Evalue=5e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR016032
- InterPro:   IPR001789
- InterPro:   IPR000792
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00196 GerE; PF00072 Response_reg [H]

EC number: NA

Molecular weight: Translated: 27039; Mature: 26908

Theoretical pI: Translated: 5.46; Mature: 5.46

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS50043 HTH_LUXR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTGAPVDAPQPPDSPPIRVFVVEDQTKILKNQLRLFENHPEMDIIGTALSGEAALEEVPK
CCCCCCCCCCCCCCCCEEEEEECCHHHHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHH
LMPDVLLLDLGLPRMSGIDVTREVKARFPKIEILIFTIFDEEDKVLEAVKAGASGYLLKG
HHHHHHHHHCCCCCCCCCCHHHHHHHHCCEEEEEEEEEECCHHHHHHHHHCCCCCEEECC
APVDKIIEAIKEVRAGGTVIQPNLARRLLRHFRVEPDASPLISPPAAPEPSASDLPQEPL
CCHHHHHHHHHHHHCCCCEECCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCHHHH
LKPLSDREREILQLIAKGVSNSEAARLLDLSKATIRTHLEHIYRKLEVTNRVEAVTEGIR
HCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KGLISV
HHHCCC
>Mature Secondary Structure 
TGAPVDAPQPPDSPPIRVFVVEDQTKILKNQLRLFENHPEMDIIGTALSGEAALEEVPK
CCCCCCCCCCCCCCCEEEEEECCHHHHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHH
LMPDVLLLDLGLPRMSGIDVTREVKARFPKIEILIFTIFDEEDKVLEAVKAGASGYLLKG
HHHHHHHHHCCCCCCCCCCHHHHHHHHCCEEEEEEEEEECCHHHHHHHHHCCCCCEEECC
APVDKIIEAIKEVRAGGTVIQPNLARRLLRHFRVEPDASPLISPPAAPEPSASDLPQEPL
CCHHHHHHHHHHHHCCCCEECCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCHHHH
LKPLSDREREILQLIAKGVSNSEAARLLDLSKATIRTHLEHIYRKLEVTNRVEAVTEGIR
HCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KGLISV
HHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7765823 [H]