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The map label for this gene is trxB [C]

Identifier: 108757522

GI number: 108757522

Start: 7032422

End: 7032808

Strand: Reverse

Name: trxB [C]

Synonym: MXAN_5670

Alternate gene names: 108757522

Gene position: 7032808-7032422 (Counterclockwise)

Preceding gene: 108759876

Following gene: 108761076

Centisome position: 76.95

GC content: 63.05

Gene sequence:

>387_bases
ATGGCAACCATCGACATCACCAAAGCCAACTTCAAGGAAATCGTCTCGAAGGAGGGAATCGTCCTCCTCGACTGGTGGGC
CGAGTGGTGCGCACCGTGCCGCACCTTCTCGCCTGTGTTCGAACAGGCGAGCACGAAGAATCCGGACCTCGTCTTCGGCA
AGCTCGACACCGACGCAGAGGTGGAACTCGCGGGGGCTTTCGCCATCCGCTCCATCCCCACGCTGATGGTCTTCCGTGAC
GGCATCATGTTGTTCGAACAGGCGGGAGCGCTGCCGGCCAACGCGCTGGATGACCTCATCCGCCAGGTGCGCGCGCTCGA
CATGAACGAGGTGCGCAAACAACTGGTGGATCGCCAGGCACAGCAGGGCGCGCCGTCCCAGGCCTGA

Upstream 100 bases:

>100_bases
GCGCTGTGCTGGAGGTGACTGGGAGTCGGGCCCTGGGGGGAGCCTGGCTGGCCACATCCTGACACTGGCGCCTCCGGGGG
GGAGGGCCCAGTGTCAGGGC

Downstream 100 bases:

>100_bases
GTCGGCACGCCTCTGTGCAGCGTGAAGACGGGCGGGGCCTCTCGGGGGGAGAGGTCTTCCGCCACGTCTTCGTTTCAGCT
CAAGACCTGCACCTTGCCGT

Product: thioredoxin

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 128; Mature: 127

Protein sequence:

>128_residues
MATIDITKANFKEIVSKEGIVLLDWWAEWCAPCRTFSPVFEQASTKNPDLVFGKLDTDAEVELAGAFAIRSIPTLMVFRD
GIMLFEQAGALPANALDDLIRQVRALDMNEVRKQLVDRQAQQGAPSQA

Sequences:

>Translated_128_residues
MATIDITKANFKEIVSKEGIVLLDWWAEWCAPCRTFSPVFEQASTKNPDLVFGKLDTDAEVELAGAFAIRSIPTLMVFRD
GIMLFEQAGALPANALDDLIRQVRALDMNEVRKQLVDRQAQQGAPSQA
>Mature_127_residues
ATIDITKANFKEIVSKEGIVLLDWWAEWCAPCRTFSPVFEQASTKNPDLVFGKLDTDAEVELAGAFAIRSIPTLMVFRDG
IMLFEQAGALPANALDDLIRQVRALDMNEVRKQLVDRQAQQGAPSQA

Specific function: Participates in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyzes dithiol-disulfide exchange reactions [H]

COG id: COG0526

COG function: function code OC; Thiol-disulfide isomerase and thioredoxins

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

Organism=Homo sapiens, GI4758304, Length=83, Percent_Identity=37.3493975903614, Blast_Score=69, Evalue=1e-12,
Organism=Homo sapiens, GI52487191, Length=111, Percent_Identity=31.5315315315315, Blast_Score=66, Evalue=9e-12,
Organism=Escherichia coli, GI1788936, Length=100, Percent_Identity=37, Blast_Score=80, Evalue=5e-17,
Organism=Escherichia coli, GI87082331, Length=99, Percent_Identity=32.3232323232323, Blast_Score=68, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI193209454, Length=82, Percent_Identity=34.1463414634146, Blast_Score=67, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI32566189, Length=82, Percent_Identity=34.1463414634146, Blast_Score=65, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17569137, Length=82, Percent_Identity=34.1463414634146, Blast_Score=65, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17507915, Length=104, Percent_Identity=26.9230769230769, Blast_Score=62, Evalue=9e-11,
Organism=Saccharomyces cerevisiae, GI6323072, Length=93, Percent_Identity=32.258064516129, Blast_Score=65, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005746
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR017937
- InterPro:   IPR013766
- InterPro:   IPR012335 [H]

Pfam domain/function: PF00085 Thioredoxin [H]

EC number: 1.8.1.8 [C]

Molecular weight: Translated: 14196; Mature: 14065

Theoretical pI: Translated: 4.42; Mature: 4.42

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATIDITKANFKEIVSKEGIVLLDWWAEWCAPCRTFSPVFEQASTKNPDLVFGKLDTDAE
CCEECCCHHHHHHHHCCCCEEEEECHHHHHHHHCHHHHHHHHHCCCCCCEEEEECCCCCC
VELAGAFAIRSIPTLMVFRDGIMLFEQAGALPANALDDLIRQVRALDMNEVRKQLVDRQA
CHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHH
QQGAPSQA
HCCCCCCC
>Mature Secondary Structure 
ATIDITKANFKEIVSKEGIVLLDWWAEWCAPCRTFSPVFEQASTKNPDLVFGKLDTDAE
CEECCCHHHHHHHHCCCCEEEEECHHHHHHHHCHHHHHHHHHCCCCCCEEEEECCCCCC
VELAGAFAIRSIPTLMVFRDGIMLFEQAGALPANALDDLIRQVRALDMNEVRKQLVDRQA
CHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHH
QQGAPSQA
HCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8652661 [H]