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The map label for this gene is thrC [H]

Identifier: 108757403

GI number: 108757403

Start: 3961949

End: 3963289

Strand: Direct

Name: thrC [H]

Synonym: MXAN_3409

Alternate gene names: 108757403

Gene position: 3961949-3963289 (Clockwise)

Preceding gene: 108758376

Following gene: 108757280

Centisome position: 43.35

GC content: 71.22

Gene sequence:

>1341_bases
ATGAGCGAGGAGTCGGCTTCGGATTTCCGCGCGGAGTACGCGTGCAGTGAGGGCTGTGACTTTCGCGCCTCGCTGATGGA
CGTGGTGTACCGGTGCCCGCGCTGCGGCGGCCTGCTGGAGGTCGCGCACGACGTGAAGGCCCTGCGCACGGTCTCCGCGG
CGGAATGGAAGCGCCGTTTCGAGACGCGCTTCGGCTCCGCGCGCCTGCCGGATGGCTCGGGCGTCTGGGGCAAGCGGGAG
TGGGCGTATCCGCAGCTCCCGGCGGAGGACATCGTCTCGCTCGGCGAGGGCCGCGTGCCGCTCAAGCCGTTGCCGCGCAT
GGCGGCGGAGCTGGGGCTGGCCGCGCTGGACTTGAAGGAGTGCGGCGTCTCGCCCACGGGCAGCTTCAAGGACTGGGGGA
TGACGGTCCTGGTCTCCGCGGTGAAGCACATGCGTGCCCGGGGCGTTCCGCTGCGCGCGGTGGCGTGTGCCTCCACGGGC
GACACGTCCGCGGCGCTCTCGGCCTACTGCGCGGCGGCGGGGATTCCGGCGGTGGTGTTCCTGCCGCGCGACAAGGTGTC
GCTCGCGCAGCTCGTGCAGCCCATTGCCAATGGGGCGCGGGTGCTGTCGCTGGACACGGACTTCGACGGCTGCATGAAGC
TGGTGCAGGCGGTGACGGCGGACACGGGGCTGTACCTGGCCAACTCGATGAACTCGCTGCGCATCGAAGGCCAGAAGATG
GTCGCCGTGGAGCTCTGCCAGGACCTGGGCTGGGAGCCGCCGGACTGGGTGGTGATTCCCGGCGGCAACCTGGGCAACGC
CAGCGCCTTGGGCAAGGGCTTCGAGCTGATGCTGTCGCTGGGGCTCATCACCCGCCGGCCGCGCATCGCCGTGGCTCAGG
CCCAGAAGGCCAACCCGCTGGTGCGCTCGTTCCGGGGCGGCTTCCAGGAGCTGGTGCCCCTGCAGGCCGAGCCTACCCTG
GCGTCGGCCATCCAGATTGGCAACCCGGTGTCATTCAAGCGCGCGGTGAAGGTGCTCAAGGCGTTCGACGGCGTGGTGGA
GGACGCCAGCGAGTCCGAGCTGGCCAACGCCGCCGCGCGGGCGGACCGCGAGGGAACCTTCACCTGTCCGCACACGGGCG
TGGCGCTGGCGGCGCTGGAGAAGCTGGTGGCGCAGGGCGTGATTGCCCGGGGCTCGCGCGTGGCGGTGGTGTCCACCGCG
CACGGCCTGAAGTTCGCCGACTTCAAGGTGGGCTACCACCGCGGCTCGCTGGCGGAGGTGACGAGCCAGTTCGCCAACCC
GCCCGTGGAGCTGCCCGCGACGCTGGACGCGGTGAAGGGCGCGCTGGCGGACCTGGGCTGA

Upstream 100 bases:

>100_bases
CTGGCGACGACGATGGCTGGCGCTCTTGCGCATCGTGTCATACTCGCGTGCGGCCCGGTAAGGCCTGTCCGGAGTGTGGC
ACGCGGGCACAGGAGGAGGC

Downstream 100 bases:

>100_bases
ACCACGGGCCCGGTCCGCCCGGCGAGAGGCGCGTCAGTCCGGCTGGAGCGGGACGCGCTTCTCGATGGTGAGCCCGAAGC
CCGCGAGCCCGCGGTAGGTG

Product: threonine synthase

Products: NA

Alternate protein names: TS [H]

Number of amino acids: Translated: 446; Mature: 445

Protein sequence:

>446_residues
MSEESASDFRAEYACSEGCDFRASLMDVVYRCPRCGGLLEVAHDVKALRTVSAAEWKRRFETRFGSARLPDGSGVWGKRE
WAYPQLPAEDIVSLGEGRVPLKPLPRMAAELGLAALDLKECGVSPTGSFKDWGMTVLVSAVKHMRARGVPLRAVACASTG
DTSAALSAYCAAAGIPAVVFLPRDKVSLAQLVQPIANGARVLSLDTDFDGCMKLVQAVTADTGLYLANSMNSLRIEGQKM
VAVELCQDLGWEPPDWVVIPGGNLGNASALGKGFELMLSLGLITRRPRIAVAQAQKANPLVRSFRGGFQELVPLQAEPTL
ASAIQIGNPVSFKRAVKVLKAFDGVVEDASESELANAAARADREGTFTCPHTGVALAALEKLVAQGVIARGSRVAVVSTA
HGLKFADFKVGYHRGSLAEVTSQFANPPVELPATLDAVKGALADLG

Sequences:

>Translated_446_residues
MSEESASDFRAEYACSEGCDFRASLMDVVYRCPRCGGLLEVAHDVKALRTVSAAEWKRRFETRFGSARLPDGSGVWGKRE
WAYPQLPAEDIVSLGEGRVPLKPLPRMAAELGLAALDLKECGVSPTGSFKDWGMTVLVSAVKHMRARGVPLRAVACASTG
DTSAALSAYCAAAGIPAVVFLPRDKVSLAQLVQPIANGARVLSLDTDFDGCMKLVQAVTADTGLYLANSMNSLRIEGQKM
VAVELCQDLGWEPPDWVVIPGGNLGNASALGKGFELMLSLGLITRRPRIAVAQAQKANPLVRSFRGGFQELVPLQAEPTL
ASAIQIGNPVSFKRAVKVLKAFDGVVEDASESELANAAARADREGTFTCPHTGVALAALEKLVAQGVIARGSRVAVVSTA
HGLKFADFKVGYHRGSLAEVTSQFANPPVELPATLDAVKGALADLG
>Mature_445_residues
SEESASDFRAEYACSEGCDFRASLMDVVYRCPRCGGLLEVAHDVKALRTVSAAEWKRRFETRFGSARLPDGSGVWGKREW
AYPQLPAEDIVSLGEGRVPLKPLPRMAAELGLAALDLKECGVSPTGSFKDWGMTVLVSAVKHMRARGVPLRAVACASTGD
TSAALSAYCAAAGIPAVVFLPRDKVSLAQLVQPIANGARVLSLDTDFDGCMKLVQAVTADTGLYLANSMNSLRIEGQKMV
AVELCQDLGWEPPDWVVIPGGNLGNASALGKGFELMLSLGLITRRPRIAVAQAQKANPLVRSFRGGFQELVPLQAEPTLA
SAIQIGNPVSFKRAVKVLKAFDGVVEDASESELANAAARADREGTFTCPHTGVALAALEKLVAQGVIARGSRVAVVSTAH
GLKFADFKVGYHRGSLAEVTSQFANPPVELPATLDAVKGALADLG

Specific function: Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine [H]

COG id: COG0498

COG function: function code E; Threonine synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the threonine synthase family [H]

Homologues:

Organism=Escherichia coli, GI1786185, Length=302, Percent_Identity=28.476821192053, Blast_Score=73, Evalue=4e-14,

Paralogues:

None

Copy number: 560 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001926
- InterPro:   IPR000634
- InterPro:   IPR004450 [H]

Pfam domain/function: PF00291 PALP [H]

EC number: =4.2.3.1 [H]

Molecular weight: Translated: 47175; Mature: 47043

Theoretical pI: Translated: 7.64; Mature: 7.64

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEESASDFRAEYACSEGCDFRASLMDVVYRCPRCGGLLEVAHDVKALRTVSAAEWKRRF
CCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
ETRFGSARLPDGSGVWGKREWAYPQLPAEDIVSLGEGRVPLKPLPRMAAELGLAALDLKE
HHHCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHCCCCCCCCCHHHHHHHHHCHHHCCHHH
CGVSPTGSFKDWGMTVLVSAVKHMRARGVPLRAVACASTGDTSAALSAYCAAAGIPAVVF
CCCCCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHCCCCEEEE
LPRDKVSLAQLVQPIANGARVLSLDTDFDGCMKLVQAVTADTGLYLANSMNSLRIEGQKM
ECCCCHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHHCCCEEECCCCCCEEECCCHH
VAVELCQDLGWEPPDWVVIPGGNLGNASALGKGFELMLSLGLITRRPRIAVAQAQKANPL
HHHHHHHHCCCCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHCCCCCEEHHHHCCCHH
VRSFRGGFQELVPLQAEPTLASAIQIGNPVSFKRAVKVLKAFDGVVEDASESELANAAAR
HHHHHCCHHHHCCCCCCCHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
ADREGTFTCPHTGVALAALEKLVAQGVIARGSRVAVVSTAHGLKFADFKVGYHRGSLAEV
CCCCCCEECCCCHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCEEEEEEECCCCCHHHHH
TSQFANPPVELPATLDAVKGALADLG
HHHHCCCCCCCCHHHHHHHHHHHCCC
>Mature Secondary Structure 
SEESASDFRAEYACSEGCDFRASLMDVVYRCPRCGGLLEVAHDVKALRTVSAAEWKRRF
CCCCCHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
ETRFGSARLPDGSGVWGKREWAYPQLPAEDIVSLGEGRVPLKPLPRMAAELGLAALDLKE
HHHCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHCCCCCCCCCHHHHHHHHHCHHHCCHHH
CGVSPTGSFKDWGMTVLVSAVKHMRARGVPLRAVACASTGDTSAALSAYCAAAGIPAVVF
CCCCCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHCCCCEEEE
LPRDKVSLAQLVQPIANGARVLSLDTDFDGCMKLVQAVTADTGLYLANSMNSLRIEGQKM
ECCCCHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHHCCCEEECCCCCCEEECCCHH
VAVELCQDLGWEPPDWVVIPGGNLGNASALGKGFELMLSLGLITRRPRIAVAQAQKANPL
HHHHHHHHCCCCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHCCCCCEEHHHHCCCHH
VRSFRGGFQELVPLQAEPTLASAIQIGNPVSFKRAVKVLKAFDGVVEDASESELANAAAR
HHHHHCCHHHHCCCCCCCHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
ADREGTFTCPHTGVALAALEKLVAQGVIARGSRVAVVSTAHGLKFADFKVGYHRGSLAEV
CCCCCCEECCCCHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCEEEEEEECCCCCHHHHH
TSQFANPPVELPATLDAVKGALADLG
HHHHCCCCCCCCHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]