Click here to switch to the map view.

The map label for this gene is ybdL [H]

Identifier: 108757334

GI number: 108757334

Start: 4468218

End: 4469408

Strand: Direct

Name: ybdL [H]

Synonym: MXAN_3751

Alternate gene names: 108757334

Gene position: 4468218-4469408 (Clockwise)

Preceding gene: 108760449

Following gene: 108763184

Centisome position: 48.89

GC content: 72.12

Gene sequence:

>1191_bases
ATGTCCAGGCCCGTAGCCGCGCAGCGAGTCACCCGGTTCGCCACTACTGTCTTCTCCGAGTTCAGCGCCCTGGCCGCCCG
CCACGGCGCGGTGAACCTGGGGCAGGGGTTCCCTGACTTCGACGGCCCGGCGGCCATCAAGGAAGCGGCGCAGCGCGCCA
TCCGCGACGGGGGCAACCAGTACGCCATGGGCGCGGGCGCCCGGGAGCTGCGCGTGGCCATCGCCGAGCACTCGGCGCGC
TTCTACGGCCAGACGGTGGACCCGGACACCATGGTGACGGTGACCAGCGGCGCCACCGAGGCCATCCTCGACACGCTGCT
GGGGCTGGTGGACCCGGGCGACGAGGTGGTGGCCTTCGAGCCCTTCTACGACTCCTACGACGCCAACATCACCTTCGTGG
GGGCCACCGCGCGCTTCGTGCCGCTGCGCCCGCCGGACGCGGACCACGCGCAGTGGTGGTTCGACCGGGACGAGGTCCGC
GCCGCCTTCAGCCCGCGCACCCGGCTGCTCATCCTCAACACGCCGCACAACCCGACGGGGAAGGTGTTCACCCGCGATGA
GCTGACGTTCCTGGGCGAGCTGTGCGCCGAGTTCGATGTGAAGGTCCTCTCCGACGAGGTGTACGAGCACCTCGTCTTCG
AGCCCGCGCGCCACCTGCGTCCGGCCACGCTGCCCGGGCTGGCCGAGCGCACCGTGACGGTGAGCAGCGGCGGGAAGACG
TTCAGCCTCACCGGCTGGAAGGTGGGCTGGGTCATCGCGCCGCCGCCGCTGCGGGACGCGGTGCAGCGGGCCCACCAGTT
CGTGACCTTCGCCACCGCCGCGCCGCTGCAGGCCGCCATGGCGGAGGCGCTGCGGTTGCCGGACGCGTACTTCACGGAGC
TGACGGCGTCCTACGCGGCGAAGCGGGAGCGGCTGCTCACCGGGCTGCGCGAGGCCGGGCTGACGGCGTTCGCCCCGGAG
GGCAGCTACTTCATCCTCGCGGACATCACGCGCCAGGGCTTCGCCGATGACGTGGCCTTCTGCCGCCACCTGGTGTCCAA
GGTGGGCGTGGCGGCCATTCCGCCCAGCGTCTTCTATGGCCCGGCGCACCGGCACCTGGGGCAGGGGCTGGCCCGTTTCG
CCTTCTGCAAGACGGATGCGGTGCTGGACGAAGCCGTGCGCCGCCTGCGCGCGGGCCTGTCGCCGCGATGA

Upstream 100 bases:

>100_bases
CCGGCAGCGCGAAGTGGCGAAGGACGCGCGTTCCGTGCCGGTGGACGCTATCGTCAGGCCCTGAGCGCCCGGACGTTGGC
GGCGCGAGGAGCCGACGTCC

Downstream 100 bases:

>100_bases
GCTTCTTCGGAGAGCTCTACCTTCGCAGCACGCTGCCGTTCCTGTCGGAGGCCGTCACCGCGCGTGAGGCGGACTACCTG
GCCCGAGCCTTCGCGGACGT

Product: class I/II aminotransferase

Products: N-succinyl-2-L-amino-6-oxoheptanedioate; L-glutamate

Alternate protein names: NA

Number of amino acids: Translated: 396; Mature: 395

Protein sequence:

>396_residues
MSRPVAAQRVTRFATTVFSEFSALAARHGAVNLGQGFPDFDGPAAIKEAAQRAIRDGGNQYAMGAGARELRVAIAEHSAR
FYGQTVDPDTMVTVTSGATEAILDTLLGLVDPGDEVVAFEPFYDSYDANITFVGATARFVPLRPPDADHAQWWFDRDEVR
AAFSPRTRLLILNTPHNPTGKVFTRDELTFLGELCAEFDVKVLSDEVYEHLVFEPARHLRPATLPGLAERTVTVSSGGKT
FSLTGWKVGWVIAPPPLRDAVQRAHQFVTFATAAPLQAAMAEALRLPDAYFTELTASYAAKRERLLTGLREAGLTAFAPE
GSYFILADITRQGFADDVAFCRHLVSKVGVAAIPPSVFYGPAHRHLGQGLARFAFCKTDAVLDEAVRRLRAGLSPR

Sequences:

>Translated_396_residues
MSRPVAAQRVTRFATTVFSEFSALAARHGAVNLGQGFPDFDGPAAIKEAAQRAIRDGGNQYAMGAGARELRVAIAEHSAR
FYGQTVDPDTMVTVTSGATEAILDTLLGLVDPGDEVVAFEPFYDSYDANITFVGATARFVPLRPPDADHAQWWFDRDEVR
AAFSPRTRLLILNTPHNPTGKVFTRDELTFLGELCAEFDVKVLSDEVYEHLVFEPARHLRPATLPGLAERTVTVSSGGKT
FSLTGWKVGWVIAPPPLRDAVQRAHQFVTFATAAPLQAAMAEALRLPDAYFTELTASYAAKRERLLTGLREAGLTAFAPE
GSYFILADITRQGFADDVAFCRHLVSKVGVAAIPPSVFYGPAHRHLGQGLARFAFCKTDAVLDEAVRRLRAGLSPR
>Mature_395_residues
SRPVAAQRVTRFATTVFSEFSALAARHGAVNLGQGFPDFDGPAAIKEAAQRAIRDGGNQYAMGAGARELRVAIAEHSARF
YGQTVDPDTMVTVTSGATEAILDTLLGLVDPGDEVVAFEPFYDSYDANITFVGATARFVPLRPPDADHAQWWFDRDEVRA
AFSPRTRLLILNTPHNPTGKVFTRDELTFLGELCAEFDVKVLSDEVYEHLVFEPARHLRPATLPGLAERTVTVSSGGKTF
SLTGWKVGWVIAPPPLRDAVQRAHQFVTFATAAPLQAAMAEALRLPDAYFTELTASYAAKRERLLTGLREAGLTAFAPEG
SYFILADITRQGFADDVAFCRHLVSKVGVAAIPPSVFYGPAHRHLGQGLARFAFCKTDAVLDEAVRRLRAGLSPR

Specific function: Shows aminotransferase activity with methionine and histidine as substrates, and to a lesser extent also with phenylalanine [H]

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI56713254, Length=407, Percent_Identity=37.1007371007371, Blast_Score=294, Evalue=1e-79,
Organism=Homo sapiens, GI56713256, Length=407, Percent_Identity=37.1007371007371, Blast_Score=294, Evalue=1e-79,
Organism=Homo sapiens, GI95147551, Length=422, Percent_Identity=36.0189573459716, Blast_Score=268, Evalue=5e-72,
Organism=Homo sapiens, GI169881279, Length=422, Percent_Identity=36.0189573459716, Blast_Score=268, Evalue=5e-72,
Organism=Homo sapiens, GI169881281, Length=420, Percent_Identity=31.6666666666667, Blast_Score=221, Evalue=1e-57,
Organism=Homo sapiens, GI4507369, Length=313, Percent_Identity=25.2396166134185, Blast_Score=96, Evalue=8e-20,
Organism=Escherichia coli, GI1786816, Length=390, Percent_Identity=41.5384615384615, Blast_Score=298, Evalue=5e-82,
Organism=Escherichia coli, GI1788722, Length=392, Percent_Identity=25.5102040816327, Blast_Score=123, Evalue=2e-29,
Organism=Escherichia coli, GI1788627, Length=350, Percent_Identity=24.2857142857143, Blast_Score=92, Evalue=7e-20,
Organism=Escherichia coli, GI1787710, Length=251, Percent_Identity=28.6852589641434, Blast_Score=72, Evalue=6e-14,
Organism=Escherichia coli, GI1787909, Length=371, Percent_Identity=27.4932614555256, Blast_Score=70, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI71994472, Length=415, Percent_Identity=35.1807228915663, Blast_Score=246, Evalue=2e-65,
Organism=Caenorhabditis elegans, GI71994476, Length=415, Percent_Identity=35.1807228915663, Blast_Score=246, Evalue=2e-65,
Organism=Caenorhabditis elegans, GI17567369, Length=412, Percent_Identity=31.5533980582524, Blast_Score=221, Evalue=7e-58,
Organism=Caenorhabditis elegans, GI17567663, Length=366, Percent_Identity=22.6775956284153, Blast_Score=85, Evalue=6e-17,
Organism=Saccharomyces cerevisiae, GI6322401, Length=384, Percent_Identity=38.5416666666667, Blast_Score=266, Evalue=6e-72,
Organism=Drosophila melanogaster, GI28573069, Length=406, Percent_Identity=37.192118226601, Blast_Score=288, Evalue=6e-78,
Organism=Drosophila melanogaster, GI24646114, Length=406, Percent_Identity=37.192118226601, Blast_Score=288, Evalue=6e-78,
Organism=Drosophila melanogaster, GI28573067, Length=406, Percent_Identity=37.192118226601, Blast_Score=288, Evalue=6e-78,
Organism=Drosophila melanogaster, GI28573065, Length=406, Percent_Identity=37.192118226601, Blast_Score=288, Evalue=6e-78,
Organism=Drosophila melanogaster, GI18859735, Length=347, Percent_Identity=27.3775216138329, Blast_Score=115, Evalue=5e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: 2.6.1.17

Molecular weight: Translated: 43094; Mature: 42963

Theoretical pI: Translated: 6.68; Mature: 6.68

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRPVAAQRVTRFATTVFSEFSALAARHGAVNLGQGFPDFDGPAAIKEAAQRAIRDGGNQ
CCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCE
YAMGAGARELRVAIAEHSARFYGQTVDPDTMVTVTSGATEAILDTLLGLVDPGDEVVAFE
EEECCCHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCHHHHHHHHHHHCCCCCCEEEEE
PFYDSYDANITFVGATARFVPLRPPDADHAQWWFDRDEVRAAFSPRTRLLILNTPHNPTG
CCCCCCCCCEEEEECCEEEEECCCCCCCCHHHCCCHHHHHHHCCCCEEEEEEECCCCCCC
KVFTRDELTFLGELCAEFDVKVLSDEVYEHLVFEPARHLRPATLPGLAERTVTVSSGGKT
CEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCCCCCCCCCCCEEEEECCCCE
FSLTGWKVGWVIAPPPLRDAVQRAHQFVTFATAAPLQAAMAEALRLPDAYFTELTASYAA
EEECCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHH
KRERLLTGLREAGLTAFAPEGSYFILADITRQGFADDVAFCRHLVSKVGVAAIPPSVFYG
HHHHHHHHHHHCCCEEECCCCCEEEEEECCCCCCHHHHHHHHHHHHHCCCHHCCCHHHCC
PAHRHLGQGLARFAFCKTDAVLDEAVRRLRAGLSPR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure 
SRPVAAQRVTRFATTVFSEFSALAARHGAVNLGQGFPDFDGPAAIKEAAQRAIRDGGNQ
CCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCE
YAMGAGARELRVAIAEHSARFYGQTVDPDTMVTVTSGATEAILDTLLGLVDPGDEVVAFE
EEECCCHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCHHHHHHHHHHHCCCCCCEEEEE
PFYDSYDANITFVGATARFVPLRPPDADHAQWWFDRDEVRAAFSPRTRLLILNTPHNPTG
CCCCCCCCCEEEEECCEEEEECCCCCCCCHHHCCCHHHHHHHCCCCEEEEEEECCCCCCC
KVFTRDELTFLGELCAEFDVKVLSDEVYEHLVFEPARHLRPATLPGLAERTVTVSSGGKT
CEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCCCCCCCCCCCEEEEECCCCE
FSLTGWKVGWVIAPPPLRDAVQRAHQFVTFATAAPLQAAMAEALRLPDAYFTELTASYAA
EEECCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHH
KRERLLTGLREAGLTAFAPEGSYFILADITRQGFADDVAFCRHLVSKVGVAAIPPSVFYG
HHHHHHHHHHHCCCEEECCCCCEEEEEECCCCCCHHHHHHHHHHHHHCCCHHCCCHHHCC
PAHRHLGQGLARFAFCKTDAVLDEAVRRLRAGLSPR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: N-succinyl-L-2,6-diaminoheptanedioate; 2-oxoglutarate

Specific reaction: N-succinyl-L-2,6-diaminoheptanedioate + 2-oxoglutarate = N-succinyl-2-L-amino-6-oxoheptanedioate + L-glutamate

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8905232; 9278503 [H]