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The map label for this gene is moaC [H]

Identifier: 108757331

GI number: 108757331

Start: 2294049

End: 2294543

Strand: Direct

Name: moaC [H]

Synonym: MXAN_1956

Alternate gene names: 108757331

Gene position: 2294049-2294543 (Clockwise)

Preceding gene: 108758343

Following gene: 108763432

Centisome position: 25.1

GC content: 72.12

Gene sequence:

>495_bases
ATGAAGATGGTGGACGTGGGGGAGAAGCCGAAGACGGGCCGCGTGGCCGTGGCCACCGCGCTGCTGCGGATGTTGCCCGA
CACGCGCGAGCGCATCCTGGCGGGGAAGGTGGAGAAGGGGGATGTGCTGGCTGCGGCGAGGCTCGCCGGCATCATGGCCG
CCAAGCGCACGCCGGACTTCGTTCCGCTCTGTCACCCCATCGCGCTCTCGGGCGTGGAGGTGACGCTGGCGCCGGAGGAC
GCGGGGCTTCGGGTCCGCGTGCAGGTGAAGACGGTGGACCGCACCGGCGTGGAGATGGAGGCCCTCACCGCGGCCTGCGC
GGCGGCGCTGACCGTCTATGACATGTGCAAGAGCGTGGACCGCGGCATGGTGCTGGACGCGGTGCAGTTGGAGCACAAGT
CGGGCGGGCGCTCCGGCACATGGCAGCGCGAGGAGGCCACGCCGGTTGAGGCGGCTGCGCCGCGGCGCCGGACGCGCGCG
AAGAAGGCCCGCTGA

Upstream 100 bases:

>100_bases
CGGGCATCCGGGAGAATCTCATCCGCGTCTCCGTGGGGTTGGAGGACCCAGACGACATCGTGGATGACCTGCTCGCCGCG
GTGGCCCAGGGGGTGCGCCG

Downstream 100 bases:

>100_bases
AGGGAGGCCTCCCCCGAAGCCGAGTCGCCCGTGCGTCGGCGGACACCGGTGGGCTGGAGCCCCGCCTTCTGTCCGTCTCC
ACACGCCGCGAATGTGACGC

Product: molybdenum cofactor biosynthesis protein C

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 164; Mature: 164

Protein sequence:

>164_residues
MKMVDVGEKPKTGRVAVATALLRMLPDTRERILAGKVEKGDVLAAARLAGIMAAKRTPDFVPLCHPIALSGVEVTLAPED
AGLRVRVQVKTVDRTGVEMEALTAACAAALTVYDMCKSVDRGMVLDAVQLEHKSGGRSGTWQREEATPVEAAAPRRRTRA
KKAR

Sequences:

>Translated_164_residues
MKMVDVGEKPKTGRVAVATALLRMLPDTRERILAGKVEKGDVLAAARLAGIMAAKRTPDFVPLCHPIALSGVEVTLAPED
AGLRVRVQVKTVDRTGVEMEALTAACAAALTVYDMCKSVDRGMVLDAVQLEHKSGGRSGTWQREEATPVEAAAPRRRTRA
KKAR
>Mature_164_residues
MKMVDVGEKPKTGRVAVATALLRMLPDTRERILAGKVEKGDVLAAARLAGIMAAKRTPDFVPLCHPIALSGVEVTLAPED
AGLRVRVQVKTVDRTGVEMEALTAACAAALTVYDMCKSVDRGMVLDAVQLEHKSGGRSGTWQREEATPVEAAAPRRRTRA
KKAR

Specific function: Together with moaA, is involved in the conversion of a guanosine derivative (5'-GTP) into molybdopterin precursor Z [H]

COG id: COG0315

COG function: function code H; Molybdenum cofactor biosynthesis enzyme

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the moaC family [H]

Homologues:

Organism=Escherichia coli, GI1787001, Length=145, Percent_Identity=53.1034482758621, Blast_Score=139, Evalue=9e-35,
Organism=Caenorhabditis elegans, GI32566331, Length=139, Percent_Identity=41.0071942446043, Blast_Score=109, Evalue=7e-25,
Organism=Drosophila melanogaster, GI28574492, Length=145, Percent_Identity=49.6551724137931, Blast_Score=128, Evalue=2e-30,
Organism=Drosophila melanogaster, GI28574490, Length=146, Percent_Identity=49.3150684931507, Blast_Score=126, Evalue=6e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023045
- InterPro:   IPR023046
- InterPro:   IPR002820 [H]

Pfam domain/function: PF01967 MoaC [H]

EC number: NA

Molecular weight: Translated: 17601; Mature: 17601

Theoretical pI: Translated: 10.42; Mature: 10.42

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
6.1 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
6.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKMVDVGEKPKTGRVAVATALLRMLPDTRERILAGKVEKGDVLAAARLAGIMAAKRTPDF
CCCCCCCCCCCCCHHHHHHHHHHHCCCHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCC
VPLCHPIALSGVEVTLAPEDAGLRVRVQVKTVDRTGVEMEALTAACAAALTVYDMCKSVD
CCCCCCEEECCEEEEECCCCCCEEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHC
RGMVLDAVQLEHKSGGRSGTWQREEATPVEAAAPRRRTRAKKAR
CCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHHCCCC
>Mature Secondary Structure
MKMVDVGEKPKTGRVAVATALLRMLPDTRERILAGKVEKGDVLAAARLAGIMAAKRTPDF
CCCCCCCCCCCCCHHHHHHHHHHHCCCHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCC
VPLCHPIALSGVEVTLAPEDAGLRVRVQVKTVDRTGVEMEALTAACAAALTVYDMCKSVD
CCCCCCEEECCEEEEECCCCCCEEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHC
RGMVLDAVQLEHKSGGRSGTWQREEATPVEAAAPRRRTRAKKAR
CCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Involved in molybdopterin biosynthesis [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA