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The map label for this gene is nhaA2 [H]

Identifier: 108757235

GI number: 108757235

Start: 3755385

End: 3757040

Strand: Reverse

Name: nhaA2 [H]

Synonym: MXAN_3206

Alternate gene names: 108757235

Gene position: 3757040-3755385 (Counterclockwise)

Preceding gene: 108760132

Following gene: 108759365

Centisome position: 41.11

GC content: 67.45

Gene sequence:

>1656_bases
GTGGTGATGAAGCAGAACCCCCTCTCCTTCCACCCGCGCGCCAAGCCCGCGGCCATCGCCGCGATGGCGGCTGGCGAGCA
GGGCAAGTACTGGGAGTACCACGCCAAGCTCTTCGCCAATCAGAAGAAGCTGGATGACGTGTCCCTGGAGCAGTACGCCA
AGGAGCTGGGCCTCAACCTGGACAAGTGGAAGGCTGAGCTGGGCAACCCCAAGTTCCAGGACATCATCACCCGCGACCAG
GCCCTGGCCGGCCAGCTGGGCGCCAGCGGCACCCCGGCCTTCTTCATCAACGGCCGCTTCCTGTCGGGCGCGCAGCCCAT
CGCCAACTTCCAGGCCCTCATCGACGAGGAGCTGGTCAAGGCGGAGAACCTGGTGAAGGGCGGCGTGCCCGCCTCGCAGG
TGTACGCGAAGATCATCGAGAAGGGCTCCGAGCGCGCCGCGCCCAAGGCGCAGCCGCAGCAGCCCGCCGCCACGGTCCGC
AAGGTGGAGATCCCCTCGGACTCGCCCTCCTTCGGCCCGGCCAACGCCAAGGTGACCATCGTCGAGTGGTCTGACTTCGA
GTGCCCCTTCTGCAGCCGCGTGGGCCCCACCCTGTCGAAGATCAAGGAGAGCTACGCCAAGGACGTGCGCGTAGTGTTCC
GTCACCAGCCGCTGCCCTTCCACCCGAACGCGAAGCTGGCCGCCGAGGCCTCGCACGCCGCGCACGAGCAGGGCAAGTTC
TGGGAGTACCACGACAAGCTCTTCGCCAATCAGAAGGCCATGGATCGCGCCTCGCTGGAGAAGTACGCGCAGGAGCTGGG
CCTGAACGTCGCCAAGTTCAAGGCCGCCCTGGATTCGGGCAAGTTCAAGGCGAAGGTCGAGGCCGACATGGCCGCCGGCA
ACGCCGTGGGCGCCAACGGCACCCCGACCTTCTTCATCAACGGCCGTGAGTTCGTCGGCGCGCAGCCCTTCGAGGCCTTC
AAGCGCGTCATCGACGAGGAGATTGGCAAGGCGGACAAGCTGCTCGCCGCCGGCACCAAGCCCGAGGAGCTCTACGCCAA
GCTGAACGCGGAGAACGTCGCCAACGCCCCGACGGCGCCCGCCGCGGCCCCTGGCGCTCCGGCCGAGCCCCCGGTCCAGA
AGGTGGACGTGGGCAACGCCCCGGTGAAGGGCGACAAGAACGCGCCCGTCACCATCGTCGCCTTCTCCGACTTCGAGTGC
CCCTTCTGCAGCCGCGTGGTGCCCACGCTGAAGCAGTTGGAGGACCAGTACGGCGGGAAGATCAAGGTCGCCTTCAAGAA
CCAGCCGCTGCCCTTCCACGCCAACGCCAAGTTGGCCGCCGCCGCTGCGCTGGCCGCGAACGAGCAGGGCAAGTTCTGGG
AGTACCACGACAAGCTCTTCGCCAATCAGCGCGCGCTGGACCGCGCCTCGCTGGAGAAGTACGCGCAGGAGCTGGGCCTG
AACGTGGACAAGTTCAAGGCCGCGCTGGACCAGGGCAAGTTCAACGCGCAGATCGAGGCCGACATGGCGCAGGCGTCCAG
CGTGGGCGCCTCCGGCACCCCGACGTTCTTCATCAATGGCCGCACGCTCGTGGGCGCCCAGCCCGTGGACGCGTTCAAGC
GCGTCATCGACGAGGAGCTGAAGAAGCTCGGCGGCGCGGTGGCCGACTCGAAGTAG

Upstream 100 bases:

>100_bases
CGTCACCGTGGTCGAGTTCTCCGACTACGAGTGCCCCTTCTGCAGCCGGGCGAACGTCACCATCGAGAAGCTCCAGGAGC
AGTACGGCAAGAAGCTCCGC

Downstream 100 bases:

>100_bases
TTCCCGCTGGGGCCCTGGCGCCCTGACGCGACAAAGGCCGTCGGACTCCTCTGAGTCCGGCGGCCTTCGTCTTTCCAGCC
CTTGCTTCAGGAGACGGCGA

Product: DSBA-like thioredoxin domain-containing protein

Products: NA

Alternate protein names: Sodium/proton antiporter nhaA 2 [H]

Number of amino acids: Translated: 551; Mature: 551

Protein sequence:

>551_residues
MVMKQNPLSFHPRAKPAAIAAMAAGEQGKYWEYHAKLFANQKKLDDVSLEQYAKELGLNLDKWKAELGNPKFQDIITRDQ
ALAGQLGASGTPAFFINGRFLSGAQPIANFQALIDEELVKAENLVKGGVPASQVYAKIIEKGSERAAPKAQPQQPAATVR
KVEIPSDSPSFGPANAKVTIVEWSDFECPFCSRVGPTLSKIKESYAKDVRVVFRHQPLPFHPNAKLAAEASHAAHEQGKF
WEYHDKLFANQKAMDRASLEKYAQELGLNVAKFKAALDSGKFKAKVEADMAAGNAVGANGTPTFFINGREFVGAQPFEAF
KRVIDEEIGKADKLLAAGTKPEELYAKLNAENVANAPTAPAAAPGAPAEPPVQKVDVGNAPVKGDKNAPVTIVAFSDFEC
PFCSRVVPTLKQLEDQYGGKIKVAFKNQPLPFHANAKLAAAAALAANEQGKFWEYHDKLFANQRALDRASLEKYAQELGL
NVDKFKAALDQGKFNAQIEADMAQASSVGASGTPTFFINGRTLVGAQPVDAFKRVIDEELKKLGGAVADSK

Sequences:

>Translated_551_residues
MVMKQNPLSFHPRAKPAAIAAMAAGEQGKYWEYHAKLFANQKKLDDVSLEQYAKELGLNLDKWKAELGNPKFQDIITRDQ
ALAGQLGASGTPAFFINGRFLSGAQPIANFQALIDEELVKAENLVKGGVPASQVYAKIIEKGSERAAPKAQPQQPAATVR
KVEIPSDSPSFGPANAKVTIVEWSDFECPFCSRVGPTLSKIKESYAKDVRVVFRHQPLPFHPNAKLAAEASHAAHEQGKF
WEYHDKLFANQKAMDRASLEKYAQELGLNVAKFKAALDSGKFKAKVEADMAAGNAVGANGTPTFFINGREFVGAQPFEAF
KRVIDEEIGKADKLLAAGTKPEELYAKLNAENVANAPTAPAAAPGAPAEPPVQKVDVGNAPVKGDKNAPVTIVAFSDFEC
PFCSRVVPTLKQLEDQYGGKIKVAFKNQPLPFHANAKLAAAAALAANEQGKFWEYHDKLFANQRALDRASLEKYAQELGL
NVDKFKAALDQGKFNAQIEADMAQASSVGASGTPTFFINGRTLVGAQPVDAFKRVIDEELKKLGGAVADSK
>Mature_551_residues
MVMKQNPLSFHPRAKPAAIAAMAAGEQGKYWEYHAKLFANQKKLDDVSLEQYAKELGLNLDKWKAELGNPKFQDIITRDQ
ALAGQLGASGTPAFFINGRFLSGAQPIANFQALIDEELVKAENLVKGGVPASQVYAKIIEKGSERAAPKAQPQQPAATVR
KVEIPSDSPSFGPANAKVTIVEWSDFECPFCSRVGPTLSKIKESYAKDVRVVFRHQPLPFHPNAKLAAEASHAAHEQGKF
WEYHDKLFANQKAMDRASLEKYAQELGLNVAKFKAALDSGKFKAKVEADMAAGNAVGANGTPTFFINGREFVGAQPFEAF
KRVIDEEIGKADKLLAAGTKPEELYAKLNAENVANAPTAPAAAPGAPAEPPVQKVDVGNAPVKGDKNAPVTIVAFSDFEC
PFCSRVVPTLKQLEDQYGGKIKVAFKNQPLPFHANAKLAAAAALAANEQGKFWEYHDKLFANQRALDRASLEKYAQELGL
NVDKFKAALDQGKFNAQIEADMAQASSVGASGTPTFFINGRTLVGAQPVDAFKRVIDEELKKLGGAVADSK

Specific function: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons [H]

COG id: COG1651

COG function: function code O; Protein-disulfide isomerase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001853
- InterPro:   IPR023171
- InterPro:   IPR004670
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF01323 DSBA; PF06965 Na_H_antiport_1 [H]

EC number: NA

Molecular weight: Translated: 59494; Mature: 59494

Theoretical pI: Translated: 8.94; Mature: 8.94

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVMKQNPLSFHPRAKPAAIAAMAAGEQGKYWEYHAKLFANQKKLDDVSLEQYAKELGLNL
CCCCCCCCCCCCCCCHHHHHHHHCCCCCCHHHHHHHHHHCHHHCCCCHHHHHHHHHCCCH
DKWKAELGNPKFQDIITRDQALAGQLGASGTPAFFINGRFLSGAQPIANFQALIDEELVK
HHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCEEEEECEEECCCCHHHHHHHHHHHHHHH
AENLVKGGVPASQVYAKIIEKGSERAAPKAQPQQPAATVRKVEIPSDSPSFGPANAKVTI
HHHHHHCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCHHEEEEECCCCCCCCCCCCCEEEE
VEWSDFECPFCSRVGPTLSKIKESYAKDVRVVFRHQPLPFHPNAKLAAEASHAAHEQGKF
EECCCCCCCHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHCCCH
WEYHDKLFANQKAMDRASLEKYAQELGLNVAKFKAALDSGKFKAKVEADMAAGNAVGANG
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCEEEEEEHHHCCCCCCCCCC
TPTFFINGREFVGAQPFEAFKRVIDEEIGKADKLLAAGTKPEELYAKLNAENVANAPTAP
CCEEEECCCHHCCCCHHHHHHHHHHHHHCCHHHHHHCCCCHHHHHHHHCHHHCCCCCCCC
AAAPGAPAEPPVQKVDVGNAPVKGDKNAPVTIVAFSDFECPFCSRVVPTLKQLEDQYGGK
CCCCCCCCCCCCCEECCCCCCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHCCE
IKVAFKNQPLPFHANAKLAAAAALAANEQGKFWEYHDKLFANQRALDRASLEKYAQELGL
EEEEECCCCCCCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
NVDKFKAALDQGKFNAQIEADMAQASSVGASGTPTFFINGRTLVGAQPVDAFKRVIDEEL
CHHHHHHHHHCCCCCEEEHHHHHHHHCCCCCCCCEEEECCEEEECCCCHHHHHHHHHHHH
KKLGGAVADSK
HHHCCCCCCCC
>Mature Secondary Structure
MVMKQNPLSFHPRAKPAAIAAMAAGEQGKYWEYHAKLFANQKKLDDVSLEQYAKELGLNL
CCCCCCCCCCCCCCCHHHHHHHHCCCCCCHHHHHHHHHHCHHHCCCCHHHHHHHHHCCCH
DKWKAELGNPKFQDIITRDQALAGQLGASGTPAFFINGRFLSGAQPIANFQALIDEELVK
HHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCEEEEECEEECCCCHHHHHHHHHHHHHHH
AENLVKGGVPASQVYAKIIEKGSERAAPKAQPQQPAATVRKVEIPSDSPSFGPANAKVTI
HHHHHHCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCHHEEEEECCCCCCCCCCCCCEEEE
VEWSDFECPFCSRVGPTLSKIKESYAKDVRVVFRHQPLPFHPNAKLAAEASHAAHEQGKF
EECCCCCCCHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHCCCH
WEYHDKLFANQKAMDRASLEKYAQELGLNVAKFKAALDSGKFKAKVEADMAAGNAVGANG
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCEEEEEEHHHCCCCCCCCCC
TPTFFINGREFVGAQPFEAFKRVIDEEIGKADKLLAAGTKPEELYAKLNAENVANAPTAP
CCEEEECCCHHCCCCHHHHHHHHHHHHHCCHHHHHHCCCCHHHHHHHHCHHHCCCCCCCC
AAAPGAPAEPPVQKVDVGNAPVKGDKNAPVTIVAFSDFECPFCSRVVPTLKQLEDQYGGK
CCCCCCCCCCCCCEECCCCCCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHCCE
IKVAFKNQPLPFHANAKLAAAAALAANEQGKFWEYHDKLFANQRALDRASLEKYAQELGL
EEEEECCCCCCCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
NVDKFKAALDQGKFNAQIEADMAQASSVGASGTPTFFINGRTLVGAQPVDAFKRVIDEEL
CHHHHHHHHHCCCCCEEEHHHHHHHHCCCCCCCCEEEECCEEEECCCCHHHHHHHHHHHH
KKLGGAVADSK
HHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA