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The map label for this gene is cirA [H]

Identifier: 108757170

GI number: 108757170

Start: 1539305

End: 1541320

Strand: Direct

Name: cirA [H]

Synonym: MXAN_1316

Alternate gene names: 108757170

Gene position: 1539305-1541320 (Clockwise)

Preceding gene: 108759613

Following gene: 108761949

Centisome position: 16.84

GC content: 70.93

Gene sequence:

>2016_bases
ATGGCGTGGCGTGGGTGTTTGCTCTTCGTGGCCTGTTCCATGCCGTGGACGGCGTGGGGCGGTGGCAGTGAAGCGCCTGC
CACCGAGGTGGCTTCCAGCGAGGCTTCCACCGCGGAGGCTCCGCCCGATGCGCAGGTGGCCCAGGCCGATGCGGGGCCGG
AGCCCGCGTTAGACGCGGAGGCGCTGCCGGAAGCGCGCACGGTGGTGACGGCGTCGCGTTCGCCGGAGCGGCTCGAGGAT
TCGGCGGTGGCCACGGAGGTCATTACCCGCTCGGACATCCTGGCCAGCGGGGCGCGGGACGCGTCGGAGTTGCTTGCCGC
GCACCCTGGGCTCCAGGTGGTGCAGACGTTCGCGGGCGCCACGGTGCAGTTGCAGGGCCTGTCGCCGGAGTACGTCCTGG
TGCTGGTGGACGGTGAGCGCGTGGCCGGCCGGGTGGCCGGAAGCGTGGACCTGTCCCGCCTGTCCACCGAGGACATCGAA
CAGGTGGAAGTCGTGAAGGGCCCCTCGTCGGTCCTCTACGGCAGTGACGCGGTGGCGGGCGTGGTGAACCTCATCACCCG
CCGTGCCCGCCGTCCGCTGGGCGCCGAGCTGCGCGCCTCCTACGGCTCCATGCAGCGGCTGGAGCTGGACGCCACCGGCG
AGGCGAAGGGCGAGAACTGGGGGCTGCGTCTGAGCGGCGGTCTGGCGCGGCGGGACGCGTACCTCCTGGACCCGACGAGC
ATCGGCACCACGGGCAGCAGCCTGGATGGCATCGACGCGTCCGCGGGCGGTGACTTGCGCATCAGTGAGGGCACGGCGTT
GCAGGCCAACGCCACCTATGCGCGTCGGGTGCAGCGGGGCGTGGACGTGGGCGTGACAGGCGCCATCTTCGACCGCGCCA
GCCGGGATGACTCGCTCTCCGTTCGCCTGTCTCCACAGTGGAGGCTGTCCAACAACGCCTCGCTGCGCGTGGATGGCGCC
TATGCGTGGTTCAACCGGCGCTACCTGAGGGACCAGCGCCGCTCCAACGCGTTGGACACCATCGAGGACACGCGCGAGCA
GCAGGGCCGGCTGGGCGCGCAACTGGACGCGAAGCTGGGAGACACCCACGCCTTCGTGGTGGGCGCGGAGCTGCTCGGCG
AATGGTTGCAGGCGGACCGGCTGGGCGAAGACGGCACCGGCCAGCGCGCCCGCGCGTCCATCTACGTGCAGGACAACTGG
ACCCTGGTGCCGCGCTTGAAGCTGACGCTGGTGCCGGGTGCGCGAGTGGACACGGACACGCAGTTCGGTACGGCGGTGAC
GCCCCGGCTGGCGGCGCGCATGGACCCGACGTCCTGGCTCACGCTGCGCGGCAGCTACGGCTGGGCGTTCCGGGCGCCGG
GCTTCCAGGAGATGCTGCTCGACTTCGAAAACCCCAGCGTGGGCTACCGGGTGCACGGCAATCCGGACCTGCGTCCGGAG
CGCTCGCGCAGCTTCAATCTGTCGGTGGAGGTGAAGCCCGCGGAGTCCTCGCTCCTGTGGGTGAGCGCCTTCCAGCACAA
CCTTCAGGACATGATTGGCGTCTCCACGGAGGTGGTCGGTCCGCAGCAGCTCTTCACCTACGTGAACATCGCGCGTGCGC
GCGTGCGCGGCGGCGAGATGGGCGTGCGTCAGCAGTTGCCCGGCCGCATCTCCGCGGAGCTGGGCTACACGCTCACCGAC
GGTCGTTCGGAGGAGACGGGGCTGGCGCTGGAAGGGCAGGCGCGCCATCGCCTCACCGCGCAGGCTACCTGGCGTCACCG
GACGTCGGGCCTGGAGGCCTGGGTGCGCGGCGCGCTCGTGGGGCCGCGTCCCTTCTACCCGGACACGGACGGTGACGGCG
TCGCCAACCCGTACGACGCGAAGACCTACGTCACCGTGGATGCCCGGCTGGGTTGGCGCATGCGCGAGGAGCTCCAGTTC
TTCGTGCTGGGCACCAACCTCGCGAACGCGGGCAACCCCACCGACCTTCCGATTCCCCCTCGCGCCATCCAGGCCGGCAT
CTCCGCCCGGCTCTGA

Upstream 100 bases:

>100_bases
CGGTGCAGTGAGGTCTTTTCCTGAGGCCCGAGGCCATTGAGCCCAGCGCCCTACAGGGCCTTCCGCGAAAGGCCCCCGGC
CTTGCGCCGGAGGACGCAGC

Downstream 100 bases:

>100_bases
CGCTCCCTTCCACCTCTCACTCAAGGAGTCCCGATGTCCCGCTTCTCTTCCCATTCCTCCTTCCTGGGCCGCGCCGCCGC
CGCCCTGCTGCTGGCCGGTT

Product: putative TonB dependent receptor

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 671; Mature: 670

Protein sequence:

>671_residues
MAWRGCLLFVACSMPWTAWGGGSEAPATEVASSEASTAEAPPDAQVAQADAGPEPALDAEALPEARTVVTASRSPERLED
SAVATEVITRSDILASGARDASELLAAHPGLQVVQTFAGATVQLQGLSPEYVLVLVDGERVAGRVAGSVDLSRLSTEDIE
QVEVVKGPSSVLYGSDAVAGVVNLITRRARRPLGAELRASYGSMQRLELDATGEAKGENWGLRLSGGLARRDAYLLDPTS
IGTTGSSLDGIDASAGGDLRISEGTALQANATYARRVQRGVDVGVTGAIFDRASRDDSLSVRLSPQWRLSNNASLRVDGA
YAWFNRRYLRDQRRSNALDTIEDTREQQGRLGAQLDAKLGDTHAFVVGAELLGEWLQADRLGEDGTGQRARASIYVQDNW
TLVPRLKLTLVPGARVDTDTQFGTAVTPRLAARMDPTSWLTLRGSYGWAFRAPGFQEMLLDFENPSVGYRVHGNPDLRPE
RSRSFNLSVEVKPAESSLLWVSAFQHNLQDMIGVSTEVVGPQQLFTYVNIARARVRGGEMGVRQQLPGRISAELGYTLTD
GRSEETGLALEGQARHRLTAQATWRHRTSGLEAWVRGALVGPRPFYPDTDGDGVANPYDAKTYVTVDARLGWRMREELQF
FVLGTNLANAGNPTDLPIPPRAIQAGISARL

Sequences:

>Translated_671_residues
MAWRGCLLFVACSMPWTAWGGGSEAPATEVASSEASTAEAPPDAQVAQADAGPEPALDAEALPEARTVVTASRSPERLED
SAVATEVITRSDILASGARDASELLAAHPGLQVVQTFAGATVQLQGLSPEYVLVLVDGERVAGRVAGSVDLSRLSTEDIE
QVEVVKGPSSVLYGSDAVAGVVNLITRRARRPLGAELRASYGSMQRLELDATGEAKGENWGLRLSGGLARRDAYLLDPTS
IGTTGSSLDGIDASAGGDLRISEGTALQANATYARRVQRGVDVGVTGAIFDRASRDDSLSVRLSPQWRLSNNASLRVDGA
YAWFNRRYLRDQRRSNALDTIEDTREQQGRLGAQLDAKLGDTHAFVVGAELLGEWLQADRLGEDGTGQRARASIYVQDNW
TLVPRLKLTLVPGARVDTDTQFGTAVTPRLAARMDPTSWLTLRGSYGWAFRAPGFQEMLLDFENPSVGYRVHGNPDLRPE
RSRSFNLSVEVKPAESSLLWVSAFQHNLQDMIGVSTEVVGPQQLFTYVNIARARVRGGEMGVRQQLPGRISAELGYTLTD
GRSEETGLALEGQARHRLTAQATWRHRTSGLEAWVRGALVGPRPFYPDTDGDGVANPYDAKTYVTVDARLGWRMREELQF
FVLGTNLANAGNPTDLPIPPRAIQAGISARL
>Mature_670_residues
AWRGCLLFVACSMPWTAWGGGSEAPATEVASSEASTAEAPPDAQVAQADAGPEPALDAEALPEARTVVTASRSPERLEDS
AVATEVITRSDILASGARDASELLAAHPGLQVVQTFAGATVQLQGLSPEYVLVLVDGERVAGRVAGSVDLSRLSTEDIEQ
VEVVKGPSSVLYGSDAVAGVVNLITRRARRPLGAELRASYGSMQRLELDATGEAKGENWGLRLSGGLARRDAYLLDPTSI
GTTGSSLDGIDASAGGDLRISEGTALQANATYARRVQRGVDVGVTGAIFDRASRDDSLSVRLSPQWRLSNNASLRVDGAY
AWFNRRYLRDQRRSNALDTIEDTREQQGRLGAQLDAKLGDTHAFVVGAELLGEWLQADRLGEDGTGQRARASIYVQDNWT
LVPRLKLTLVPGARVDTDTQFGTAVTPRLAARMDPTSWLTLRGSYGWAFRAPGFQEMLLDFENPSVGYRVHGNPDLRPER
SRSFNLSVEVKPAESSLLWVSAFQHNLQDMIGVSTEVVGPQQLFTYVNIARARVRGGEMGVRQQLPGRISAELGYTLTDG
RSEETGLALEGQARHRLTAQATWRHRTSGLEAWVRGALVGPRPFYPDTDGDGVANPYDAKTYVTVDARLGWRMREELQFF
VLGTNLANAGNPTDLPIPPRAIQAGISARL

Specific function: Not yet known. Postulated to participate in iron transport. Outer membrane receptor for colicins IA and IB [H]

COG id: COG4771

COG function: function code P; Outer membrane receptor for ferrienterochelin and colicins

Gene ontology:

Cell location: Cell outer membrane [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tonB-dependent receptor family [H]

Homologues:

Organism=Escherichia coli, GI1788478, Length=591, Percent_Identity=26.7343485617597, Blast_Score=149, Evalue=6e-37,
Organism=Escherichia coli, GI1790405, Length=546, Percent_Identity=26.7399267399267, Blast_Score=111, Evalue=1e-25,
Organism=Escherichia coli, GI1786798, Length=214, Percent_Identity=29.4392523364486, Blast_Score=65, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012910
- InterPro:   IPR000531
- InterPro:   IPR010916
- InterPro:   IPR010917 [H]

Pfam domain/function: PF07715 Plug; PF00593 TonB_dep_Rec [H]

EC number: NA

Molecular weight: Translated: 72332; Mature: 72200

Theoretical pI: Translated: 5.09; Mature: 5.09

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAWRGCLLFVACSMPWTAWGGGSEAPATEVASSEASTAEAPPDAQVAQADAGPEPALDAE
CCCCCEEEEEEECCCCEECCCCCCCCHHHHHCCCCCCCCCCCCCHHCCCCCCCCCCCCHH
ALPEARTVVTASRSPERLEDSAVATEVITRSDILASGARDASELLAAHPGLQVVQTFAGA
HCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHCCCCHHHHHHHCCC
TVQLQGLSPEYVLVLVDGERVAGRVAGSVDLSRLSTEDIEQVEVVKGPSSVLYGSDAVAG
EEEEECCCCCEEEEEECCCHHCCCEECCCCHHHCCHHHHHHEEEECCCCCEEECCHHHHH
VVNLITRRARRPLGAELRASYGSMQRLELDATGEAKGENWGLRLSGGLARRDAYLLDPTS
HHHHHHHHHCCCCCHHHHHCCCCCEEEEECCCCCCCCCCCCEEEECCCCCCCEEEECCCC
IGTTGSSLDGIDASAGGDLRISEGTALQANATYARRVQRGVDVGVTGAIFDRASRDDSLS
CCCCCCCCCCCCCCCCCCEEECCCCEEECCCHHHHHHHHCCCCCEEHHHHHCCCCCCCEE
VRLSPQWRLSNNASLRVDGAYAWFNRRYLRDQRRSNALDTIEDTREQQGRLGAQLDAKLG
EEECCCEEECCCCEEEECCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCEEECCCC
DTHAFVVGAELLGEWLQADRLGEDGTGQRARASIYVQDNWTLVPRLKLTLVPGARVDTDT
CCEEEEEEHHHHHHHHHHHCCCCCCCCCCEEEEEEEECCEEEEEEEEEEEECCCCCCCCC
QFGTAVTPRLAARMDPTSWLTLRGSYGWAFRAPGFQEMLLDFENPSVGYRVHGNPDLRPE
CCCCCCCCHHHHCCCCCEEEEEECCCCEEECCCCHHHHHEECCCCCCCEEECCCCCCCCC
RSRSFNLSVEVKPAESSLLWVSAFQHNLQDMIGVSTEVVGPQQLFTYVNIARARVRGGEM
CCCCEEEEEEEECCCCCEEEHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCCCC
GVRQQLPGRISAELGYTLTDGRSEETGLALEGQARHRLTAQATWRHRTSGLEAWVRGALV
CHHHHCCCCEECCCCEEEECCCCCCCCEEECCCCCCEEEEHHHHHHHHHHHHHHHHCCCC
GPRPFYPDTDGDGVANPYDAKTYVTVDARLGWRMREELQFFVLGTNLANAGNPTDLPIPP
CCCCCCCCCCCCCCCCCCCCEEEEEEECCCCCCCCCCEEEEEEECCCCCCCCCCCCCCCH
RAIQAGISARL
HHHHHCHHCCC
>Mature Secondary Structure 
AWRGCLLFVACSMPWTAWGGGSEAPATEVASSEASTAEAPPDAQVAQADAGPEPALDAE
CCCCEEEEEEECCCCEECCCCCCCCHHHHHCCCCCCCCCCCCCHHCCCCCCCCCCCCHH
ALPEARTVVTASRSPERLEDSAVATEVITRSDILASGARDASELLAAHPGLQVVQTFAGA
HCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHCCCCHHHHHHHCCC
TVQLQGLSPEYVLVLVDGERVAGRVAGSVDLSRLSTEDIEQVEVVKGPSSVLYGSDAVAG
EEEEECCCCCEEEEEECCCHHCCCEECCCCHHHCCHHHHHHEEEECCCCCEEECCHHHHH
VVNLITRRARRPLGAELRASYGSMQRLELDATGEAKGENWGLRLSGGLARRDAYLLDPTS
HHHHHHHHHCCCCCHHHHHCCCCCEEEEECCCCCCCCCCCCEEEECCCCCCCEEEECCCC
IGTTGSSLDGIDASAGGDLRISEGTALQANATYARRVQRGVDVGVTGAIFDRASRDDSLS
CCCCCCCCCCCCCCCCCCEEECCCCEEECCCHHHHHHHHCCCCCEEHHHHHCCCCCCCEE
VRLSPQWRLSNNASLRVDGAYAWFNRRYLRDQRRSNALDTIEDTREQQGRLGAQLDAKLG
EEECCCEEECCCCEEEECCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCEEECCCC
DTHAFVVGAELLGEWLQADRLGEDGTGQRARASIYVQDNWTLVPRLKLTLVPGARVDTDT
CCEEEEEEHHHHHHHHHHHCCCCCCCCCCEEEEEEEECCEEEEEEEEEEEECCCCCCCCC
QFGTAVTPRLAARMDPTSWLTLRGSYGWAFRAPGFQEMLLDFENPSVGYRVHGNPDLRPE
CCCCCCCCHHHHCCCCCEEEEEECCCCEEECCCCHHHHHEECCCCCCCEEECCCCCCCCC
RSRSFNLSVEVKPAESSLLWVSAFQHNLQDMIGVSTEVVGPQQLFTYVNIARARVRGGEM
CCCCEEEEEEEECCCCCEEEHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCCCC
GVRQQLPGRISAELGYTLTDGRSEETGLALEGQARHRLTAQATWRHRTSGLEAWVRGALV
CHHHHCCCCEECCCCEEEECCCCCCCCEEECCCCCCEEEEHHHHHHHHHHHHHHHHCCCC
GPRPFYPDTDGDGVANPYDAKTYVTVDARLGWRMREELQFFVLGTNLANAGNPTDLPIPP
CCCCCCCCCCCCCCCCCCCCEEEEEEECCCCCCCCCCEEEEEEECCCCCCCCCCCCCCCH
RAIQAGISARL
HHHHHCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2644220; 9278503; 3316180; 1315732; 2160948 [H]