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The map label for this gene is masK [H]

Identifier: 108757059

GI number: 108757059

Start: 6058815

End: 6060029

Strand: Reverse

Name: masK [H]

Synonym: MXAN_4841

Alternate gene names: 108757059

Gene position: 6060029-6058815 (Counterclockwise)

Preceding gene: 108763545

Following gene: 108757780

Centisome position: 66.3

GC content: 64.44

Gene sequence:

>1215_bases
ATGCGGCAGGTAGCTTCTTTCGCCGCGTTGGTCGCGAGTCTGCGCACGAGGGGAAACGGCATGTCGAAAGCAATCGAGTT
CAAGATCCCGCCAGGGGCGATTCTCTTCTCGGCGGATGGCGTCGGCTACGAGTTCCGCGAGGACTTGGGGCCGACGAACC
ATGGGATGTCCCTCTTCGTGGCTCGGCTGCGAACCGCGTCGGGGGAGCCTCGTGGAAAGGTGCTGCTCAAGGCGGTTCCT
GCGCCATCGGAGAAGGAAGGGGGGCGGGTTCGGCGGGCGCGAGCAAAGCTGGATGAGCAGGTTCGTCTTGCCGCCTCTCT
TTCTCATCCCGCGATCCTCAAGGTCCATGGGCTCCATAAGGTTGAGGGCTACTGGTACGTCAGCGCCGAGCATCCATCCG
GGAATTCGCTGAACGAACTGCTGACGCTTGTTGTCGAGTGCCGTCGATGGTTCTCGCCCCTCTTCGTGATGTTCGTAGGC
TCGCAGGTGGCGGCAGCTCTAGAGCACGCGCACACGGCGAAGGATGCCAGCGGGCGCCCCTTGAACATCGTTCACCGAGC
TATCGATGTCGCGCACATCTTTATCGACTGGGACGGGACGGTTCGGCTCGGCGACTTCGGTCTCGCGCTGTCCAACTTGC
CGGGGCGCGTGGCTTCCTCGGTTCGCAGCCCGCGAGGGGACTACTTCTATTCGTCGCCTGAGATGCTGCTTGGCGGGCCC
GTTGACGCGCGCTCGGACCTCTTCATGTTGGGGGTGGTGCTGCTCGAAATGGCGACGGGGAAGAATCTGCTCTTCTGCCC
GGATGCCATCACGCCCGAGGTCATGGGCTCGTTGTCCGTGAAGCGGCGTCGGCGAGTCGTTCAGGCAATCAAGCGGGCCA
CGCTGGCCGGGGCGTCATCCATGGTAGAGGACGCGATTTGGCGTGCCGCGACGCTGGCGGATGCTGACGTGGACGCGATG
ACGGAGGGGCTTCCCCAGGGGCTTCGCGTAACGCTGAACCGGCTTCTTCGGGTCTCCCCCCGCGAGCGCTACCAGTCTGC
CGGTGAGCTGGCCGCAGACCTGGCTGCCTGGATTGGGGGCACCTTCACGAAGACTGATGCCGCTGCGGAACTCAGGGCAC
GTGCAGCTCAGGCAGAAGAGGCGCTGGATGCGATGGGGCTCACGCCGCCTCGCGGTCGCGGCAAGCGCAAGTCGGATGAT
GTGACGACGGCGTGA

Upstream 100 bases:

>100_bases
GGCCATGAGAGCCCCGAAAGGACGTAGCAGGTAGGAGGCCGAAATTGGGCCGACCAAGCCGTTTTGTCCTCATGACCTGT
GAAGGCGTTCCCTCGGCTGG

Downstream 100 bases:

>100_bases
CCGACTGGGGGCGGCATTTGGGCCGTTTCCATGTTGCACGTATGTCGCATGAGGCTGCGGAATCGGCCGGTACAGGGTGG
GACAGCAGGGCACGAGACGG

Product: putative serine/threonine protein kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 404; Mature: 404

Protein sequence:

>404_residues
MRQVASFAALVASLRTRGNGMSKAIEFKIPPGAILFSADGVGYEFREDLGPTNHGMSLFVARLRTASGEPRGKVLLKAVP
APSEKEGGRVRRARAKLDEQVRLAASLSHPAILKVHGLHKVEGYWYVSAEHPSGNSLNELLTLVVECRRWFSPLFVMFVG
SQVAAALEHAHTAKDASGRPLNIVHRAIDVAHIFIDWDGTVRLGDFGLALSNLPGRVASSVRSPRGDYFYSSPEMLLGGP
VDARSDLFMLGVVLLEMATGKNLLFCPDAITPEVMGSLSVKRRRRVVQAIKRATLAGASSMVEDAIWRAATLADADVDAM
TEGLPQGLRVTLNRLLRVSPRERYQSAGELAADLAAWIGGTFTKTDAAAELRARAAQAEEALDAMGLTPPRGRGKRKSDD
VTTA

Sequences:

>Translated_404_residues
MRQVASFAALVASLRTRGNGMSKAIEFKIPPGAILFSADGVGYEFREDLGPTNHGMSLFVARLRTASGEPRGKVLLKAVP
APSEKEGGRVRRARAKLDEQVRLAASLSHPAILKVHGLHKVEGYWYVSAEHPSGNSLNELLTLVVECRRWFSPLFVMFVG
SQVAAALEHAHTAKDASGRPLNIVHRAIDVAHIFIDWDGTVRLGDFGLALSNLPGRVASSVRSPRGDYFYSSPEMLLGGP
VDARSDLFMLGVVLLEMATGKNLLFCPDAITPEVMGSLSVKRRRRVVQAIKRATLAGASSMVEDAIWRAATLADADVDAM
TEGLPQGLRVTLNRLLRVSPRERYQSAGELAADLAAWIGGTFTKTDAAAELRARAAQAEEALDAMGLTPPRGRGKRKSDD
VTTA
>Mature_404_residues
MRQVASFAALVASLRTRGNGMSKAIEFKIPPGAILFSADGVGYEFREDLGPTNHGMSLFVARLRTASGEPRGKVLLKAVP
APSEKEGGRVRRARAKLDEQVRLAASLSHPAILKVHGLHKVEGYWYVSAEHPSGNSLNELLTLVVECRRWFSPLFVMFVG
SQVAAALEHAHTAKDASGRPLNIVHRAIDVAHIFIDWDGTVRLGDFGLALSNLPGRVASSVRSPRGDYFYSSPEMLLGGP
VDARSDLFMLGVVLLEMATGKNLLFCPDAITPEVMGSLSVKRRRRVVQAIKRATLAGASSMVEDAIWRAATLADADVDAM
TEGLPQGLRVTLNRLLRVSPRERYQSAGELAADLAAWIGGTFTKTDAAAELRARAAQAEEALDAMGLTPPRGRGKRKSDD
VTTA

Specific function: Essential for growth. Interacts with mglA to control social gliding motility [H]

COG id: COG0515

COG function: function code RTKL; Serine/threonine protein kinase

Gene ontology:

Cell location: Cell inner membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 protein kinase domain [H]

Homologues:

Organism=Homo sapiens, GI4505373, Length=161, Percent_Identity=27.9503105590062, Blast_Score=75, Evalue=8e-14,
Organism=Homo sapiens, GI41872673, Length=175, Percent_Identity=30.2857142857143, Blast_Score=68, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI133951926, Length=180, Percent_Identity=28.3333333333333, Blast_Score=71, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI133951912, Length=180, Percent_Identity=28.3333333333333, Blast_Score=71, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI71989905, Length=224, Percent_Identity=29.4642857142857, Blast_Score=69, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI71989900, Length=224, Percent_Identity=29.4642857142857, Blast_Score=69, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI193203107, Length=224, Percent_Identity=29.4642857142857, Blast_Score=69, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI71989893, Length=224, Percent_Identity=29.4642857142857, Blast_Score=69, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI71989911, Length=224, Percent_Identity=29.4642857142857, Blast_Score=68, Evalue=7e-12,
Organism=Caenorhabditis elegans, GI133901968, Length=282, Percent_Identity=23.0496453900709, Blast_Score=68, Evalue=8e-12,
Organism=Caenorhabditis elegans, GI133901970, Length=282, Percent_Identity=23.0496453900709, Blast_Score=68, Evalue=9e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011009
- InterPro:   IPR000719
- InterPro:   IPR017442
- InterPro:   IPR008266 [H]

Pfam domain/function: PF00069 Pkinase [H]

EC number: =2.7.10.2 [H]

Molecular weight: Translated: 43557; Mature: 43557

Theoretical pI: Translated: 10.15; Mature: 10.15

Prosite motif: PS50011 PROTEIN_KINASE_DOM

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRQVASFAALVASLRTRGNGMSKAIEFKIPPGAILFSADGVGYEFREDLGPTNHGMSLFV
CCHHHHHHHHHHHHHHCCCCCCCEEEEECCCCEEEEECCCCCCHHHHHCCCCCCCHHHHH
ARLRTASGEPRGKVLLKAVPAPSEKEGGRVRRARAKLDEQVRLAASLSHPAILKVHGLHK
HHHHHCCCCCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEEECCEE
VEGYWYVSAEHPSGNSLNELLTLVVECRRWFSPLFVMFVGSQVAAALEHAHTAKDASGRP
ECEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
LNIVHRAIDVAHIFIDWDGTVRLGDFGLALSNLPGRVASSVRSPRGDYFYSSPEMLLGGP
HHHHHHHHEEEEEEEECCCEEEECCHHHHHHCCCHHHHHHHCCCCCCEEECCCCEEECCC
VDARSDLFMLGVVLLEMATGKNLLFCPDAITPEVMGSLSVKRRRRVVQAIKRATLAGASS
CCCCCHHHHHHHHHHHHHCCCCEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MVEDAIWRAATLADADVDAMTEGLPQGLRVTLNRLLRVSPRERYQSAGELAADLAAWIGG
HHHHHHHHHHHHCCCCHHHHHHCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCC
TFTKTDAAAELRARAAQAEEALDAMGLTPPRGRGKRKSDDVTTA
CCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MRQVASFAALVASLRTRGNGMSKAIEFKIPPGAILFSADGVGYEFREDLGPTNHGMSLFV
CCHHHHHHHHHHHHHHCCCCCCCEEEEECCCCEEEEECCCCCCHHHHHCCCCCCCHHHHH
ARLRTASGEPRGKVLLKAVPAPSEKEGGRVRRARAKLDEQVRLAASLSHPAILKVHGLHK
HHHHHCCCCCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEEECCEE
VEGYWYVSAEHPSGNSLNELLTLVVECRRWFSPLFVMFVGSQVAAALEHAHTAKDASGRP
ECEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
LNIVHRAIDVAHIFIDWDGTVRLGDFGLALSNLPGRVASSVRSPRGDYFYSSPEMLLGGP
HHHHHHHHEEEEEEEECCCEEEECCHHHHHHCCCHHHHHHHCCCCCCEEECCCCEEECCC
VDARSDLFMLGVVLLEMATGKNLLFCPDAITPEVMGSLSVKRRRRVVQAIKRATLAGASS
CCCCCHHHHHHHHHHHHHCCCCEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MVEDAIWRAATLADADVDAMTEGLPQGLRVTLNRLLRVSPRERYQSAGELAADLAAWIGG
HHHHHHHHHHHHCCCCHHHHHHCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCC
TFTKTDAAAELRARAAQAEEALDAMGLTPPRGRGKRKSDDVTTA
CCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2464581 [H]