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The map label for this gene is pepE [H]

Identifier: 108756950

GI number: 108756950

Start: 871681

End: 873138

Strand: Reverse

Name: pepE [H]

Synonym: MXAN_0764

Alternate gene names: 108756950

Gene position: 873138-871681 (Counterclockwise)

Preceding gene: 108761441

Following gene: 108761043

Centisome position: 9.55

GC content: 71.12

Gene sequence:

>1458_bases
ATGGTGGGCTTCGCACGGTTCTTCGCACGCACGCCACACGACTTCACGCCGCGCGCGTCCCTTCCCACCGGGCGCGAGGG
GATGATGGCGTTCCTTCCCGAAAGGACTGCTCCCCGCATGACTCGCGTCCGGCACGCCCTGCTCTCCGCCCTGCTCCTCG
CCACCCCCATCGCCAGCGCCGCGCCCGCCGACCCCATCGCGTCCCAGGACGACTGGCCCCGCCTCCGCAAGGAGCGCATC
CAGAAACTGCTGCCCCAGGCCATGGCCCGCGCCAACGTGGACGCGTGGGTGGTCATCTGCCGGGAGAACGACAACGACCC
GCTGGCCATCCACGTCGGGTGTGAGAACGCCGGAGGCACCGCCGCCTTCCTGTTCCTCAAGCAGGACGCGGCCGTGCGCG
GCGTGGCCCTGTCACCGGAAGGCGAGGCCACCGCGCTCCGCGACGTGGCGCCGCTCGATGAGGTGGTGCCGCTGCCGCGC
GGAACGAATCTCTACGCGCAGCTGGCCTCGCGGCTGGCGGCGGCGAAGCCGAAGCGCATCGCCGTCAATTCGTCCACGTC
GGTGGCGGTGGCCGATGGCCTGTCCGCCACGCAGCGCGCCGCGCTGGAGAAGGCCCTGACGCCCGCGTTGCGCAAGAAGT
TGGTGTCCTCCGAGGACCTCGTCTCCGAGTGGCTCTCCGTGAAGCTGCCCGAGGAGGTGGACATCCTCCGCAAGGCCGCC
GCGCTGACGTCCCAGATGGAGATAGAGGCCTACCGCGCGGTAGTGCCGGGCAAGACGCGCGACGTGGATGTGGCCCGCTT
CCTCCGCCAGCGCATGGCGGAACTGGGCGTGGGCGACGCCTGGGCGCCGGACCAGAACCCCAACGTCCAGAGCGGCCCCA
CGCGCGGGCACTCCCACGCCACCGAGCGCGTCATCCAGCCGGGTGACTTCATCCAGACGGACTTCGGCATCCGCGTGGGC
GGCATGTGGGTGACGGACATCCAGCGCTTCGCCTACGTGCTGGCGCCGGGCGAGACGCAGCCGCCCAAGGAGGCCCTGGA
GAAGTGGGAGAAGGGCAAGAAAGGCAGCCGGATTGCATTGGCCACCCTGAAACCCGGCGTGCGCGGCTGGGACGTGGACA
AGGCCCAGCGCGACTGGATGCGGGAAGCCGGCTCCGCGCCCGTCATGTGGGGAACGGGGCACCCGGTGGGCTACTGGGCG
CATGACGTGGGCCCGGCGCTCTCCGGCGCGCAGCAGGGCAAGCCCGCGGCGGGACAGGCGGCGCGCATCGTCCGGCCCGG
GCAGGTCTTCGCCTTCGACGGGTTCTTCGCGTGGCCGGACGGCGGCGAGGGCGAGCAGCGCATCATCGCCGTGGAGGAGA
TGGCCGTCGTCACCGAAACGGGTGCGGAATACCTCATCCCACCCCAGGAAGATTTGGTGCTCATCCCCTCCCCGGGTCCT
TCCCGCCCCGTGCCGTGA

Upstream 100 bases:

>100_bases
GCGGGCTTCTTCGCCTTCGACGGACGCTTCTGGGAAGTGCTCTTGGCCATGGACACACCTTAAACGAGCCACGGCGACAA
CGCTTGCATGGTGCCGCCCG

Downstream 100 bases:

>100_bases
GACATGTCTCGCGTGACAATCTCGTGGGAGAAGCTTGAGTAGGATGCGCTGAACCGCTCGCGGAGAGGGCCCGATGCAGA
ACGTGCTGGTGATTGACGAC

Product: M24 family peptidase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 485; Mature: 485

Protein sequence:

>485_residues
MVGFARFFARTPHDFTPRASLPTGREGMMAFLPERTAPRMTRVRHALLSALLLATPIASAAPADPIASQDDWPRLRKERI
QKLLPQAMARANVDAWVVICRENDNDPLAIHVGCENAGGTAAFLFLKQDAAVRGVALSPEGEATALRDVAPLDEVVPLPR
GTNLYAQLASRLAAAKPKRIAVNSSTSVAVADGLSATQRAALEKALTPALRKKLVSSEDLVSEWLSVKLPEEVDILRKAA
ALTSQMEIEAYRAVVPGKTRDVDVARFLRQRMAELGVGDAWAPDQNPNVQSGPTRGHSHATERVIQPGDFIQTDFGIRVG
GMWVTDIQRFAYVLAPGETQPPKEALEKWEKGKKGSRIALATLKPGVRGWDVDKAQRDWMREAGSAPVMWGTGHPVGYWA
HDVGPALSGAQQGKPAAGQAARIVRPGQVFAFDGFFAWPDGGEGEQRIIAVEEMAVVTETGAEYLIPPQEDLVLIPSPGP
SRPVP

Sequences:

>Translated_485_residues
MVGFARFFARTPHDFTPRASLPTGREGMMAFLPERTAPRMTRVRHALLSALLLATPIASAAPADPIASQDDWPRLRKERI
QKLLPQAMARANVDAWVVICRENDNDPLAIHVGCENAGGTAAFLFLKQDAAVRGVALSPEGEATALRDVAPLDEVVPLPR
GTNLYAQLASRLAAAKPKRIAVNSSTSVAVADGLSATQRAALEKALTPALRKKLVSSEDLVSEWLSVKLPEEVDILRKAA
ALTSQMEIEAYRAVVPGKTRDVDVARFLRQRMAELGVGDAWAPDQNPNVQSGPTRGHSHATERVIQPGDFIQTDFGIRVG
GMWVTDIQRFAYVLAPGETQPPKEALEKWEKGKKGSRIALATLKPGVRGWDVDKAQRDWMREAGSAPVMWGTGHPVGYWA
HDVGPALSGAQQGKPAAGQAARIVRPGQVFAFDGFFAWPDGGEGEQRIIAVEEMAVVTETGAEYLIPPQEDLVLIPSPGP
SRPVP
>Mature_485_residues
MVGFARFFARTPHDFTPRASLPTGREGMMAFLPERTAPRMTRVRHALLSALLLATPIASAAPADPIASQDDWPRLRKERI
QKLLPQAMARANVDAWVVICRENDNDPLAIHVGCENAGGTAAFLFLKQDAAVRGVALSPEGEATALRDVAPLDEVVPLPR
GTNLYAQLASRLAAAKPKRIAVNSSTSVAVADGLSATQRAALEKALTPALRKKLVSSEDLVSEWLSVKLPEEVDILRKAA
ALTSQMEIEAYRAVVPGKTRDVDVARFLRQRMAELGVGDAWAPDQNPNVQSGPTRGHSHATERVIQPGDFIQTDFGIRVG
GMWVTDIQRFAYVLAPGETQPPKEALEKWEKGKKGSRIALATLKPGVRGWDVDKAQRDWMREAGSAPVMWGTGHPVGYWA
HDVGPALSGAQQGKPAAGQAARIVRPGQVFAFDGFFAWPDGGEGEQRIIAVEEMAVVTETGAEYLIPPQEDLVLIPSPGP
SRPVP

Specific function: Unknown

COG id: COG0006

COG function: function code E; Xaa-Pro aminopeptidase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M24B family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000587
- InterPro:   IPR000994
- InterPro:   IPR001131 [H]

Pfam domain/function: PF01321 Creatinase_N; PF00557 Peptidase_M24 [H]

EC number: 3.4.-.- [C]

Molecular weight: Translated: 52380; Mature: 52380

Theoretical pI: Translated: 8.24; Mature: 8.24

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVGFARFFARTPHDFTPRASLPTGREGMMAFLPERTAPRMTRVRHALLSALLLATPIASA
CCCHHHHHHCCCCCCCCCCCCCCCCCCCEEECCCCCCHHHHHHHHHHHHHHHHHHCCCCC
APADPIASQDDWPRLRKERIQKLLPQAMARANVDAWVVICRENDNDPLAIHVGCENAGGT
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCEEEEEECCCCCCC
AAFLFLKQDAAVRGVALSPEGEATALRDVAPLDEVVPLPRGTNLYAQLASRLAAAKPKRI
EEEEEEECCCCEEEEEECCCCCCHHHHHHCCHHHHCCCCCCCCHHHHHHHHHHHCCCCEE
AVNSSTSVAVADGLSATQRAALEKALTPALRKKLVSSEDLVSEWLSVKLPEEVDILRKAA
EECCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCHHHHHHHHHH
ALTSQMEIEAYRAVVPGKTRDVDVARFLRQRMAELGVGDAWAPDQNPNVQSGPTRGHSHA
HHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCHH
TERVIQPGDFIQTDFGIRVGGMWVTDIQRFAYVLAPGETQPPKEALEKWEKGKKGSRIAL
HHHHCCCCCCEECCCCEEECCEEHHHHHHHEEEECCCCCCCHHHHHHHHHCCCCCCEEEE
ATLKPGVRGWDVDKAQRDWMREAGSAPVMWGTGHPVGYWAHDVGPALSGAQQGKPAAGQA
EEECCCCCCCCCCHHHHHHHHHCCCCCEEECCCCCCCCCHHHHCHHHCCCCCCCCCCCCC
ARIVRPGQVFAFDGFFAWPDGGEGEQRIIAVEEMAVVTETGAEYLIPPQEDLVLIPSPGP
CEEECCCEEEEECCEEECCCCCCCCCEEEEEHHHEEEECCCCCCCCCCCCCEEEECCCCC
SRPVP
CCCCC
>Mature Secondary Structure
MVGFARFFARTPHDFTPRASLPTGREGMMAFLPERTAPRMTRVRHALLSALLLATPIASA
CCCHHHHHHCCCCCCCCCCCCCCCCCCCEEECCCCCCHHHHHHHHHHHHHHHHHHCCCCC
APADPIASQDDWPRLRKERIQKLLPQAMARANVDAWVVICRENDNDPLAIHVGCENAGGT
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCEEEEEECCCCCCC
AAFLFLKQDAAVRGVALSPEGEATALRDVAPLDEVVPLPRGTNLYAQLASRLAAAKPKRI
EEEEEEECCCCEEEEEECCCCCCHHHHHHCCHHHHCCCCCCCCHHHHHHHHHHHCCCCEE
AVNSSTSVAVADGLSATQRAALEKALTPALRKKLVSSEDLVSEWLSVKLPEEVDILRKAA
EECCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCHHHHHHHHHH
ALTSQMEIEAYRAVVPGKTRDVDVARFLRQRMAELGVGDAWAPDQNPNVQSGPTRGHSHA
HHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCHH
TERVIQPGDFIQTDFGIRVGGMWVTDIQRFAYVLAPGETQPPKEALEKWEKGKKGSRIAL
HHHHCCCCCCEECCCCEEECCEEHHHHHHHEEEECCCCCCCHHHHHHHHHCCCCCCEEEE
ATLKPGVRGWDVDKAQRDWMREAGSAPVMWGTGHPVGYWAHDVGPALSGAQQGKPAAGQA
EEECCCCCCCCCCHHHHHHHHHCCCCCEEECCCCCCCCCHHHHCHHHCCCCCCCCCCCCC
ARIVRPGQVFAFDGFFAWPDGGEGEQRIIAVEEMAVVTETGAEYLIPPQEDLVLIPSPGP
CEEECCCEEEEECCEEECCCCCCCCCEEEEEHHHEEEECCCCCCCCCCCCCEEEECCCCC
SRPVP
CCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]