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The map label for this gene is yhcR [H]

Identifier: 108756897

GI number: 108756897

Start: 2875400

End: 2876941

Strand: Direct

Name: yhcR [H]

Synonym: MXAN_2470

Alternate gene names: 108756897

Gene position: 2875400-2876941 (Clockwise)

Preceding gene: 108759535

Following gene: 108758806

Centisome position: 31.46

GC content: 69.84

Gene sequence:

>1542_bases
GTGAGCGCGAACCCTCTCCGTCCTCGTCCCTTCCGCCAGCCGCTGTCCGGCGTGCTGGTCCTCGCCCTCGGTGTCGTCGC
CGGCTGCGAGAAGAGCAATCCCACTCCTCCTCCGGCCGCCGCGCCGGAAGCCAAGGCTCCCGTTGCTCCTTCCGAAGTCA
CGCTGCTCGTGACGGGTGGCGCGTTCGGTCAGCTCCAGCCCTCCGAGGGCAAGGGCGGCGCGGCGGAGCTGCTCGGCCGC
TGGATGGCCGATGAGAAGCACTGTCCCGGTCCCGTGAAGGAGGGCCAGCCTACGTGCGCGGACGCCAGCACGCTGGCGCT
CGCCACGGGTGACCACTGGAACGGCCCGGCCATCTCCTCCTTCTTCCTGGGCACGCCCACGGCCGAGGTCATGGGCCGCA
TGGGCTACGCCGCCTCCGCCCTGGGCAACCATGAGCTGGCCTTCGGCAAGGAGGCCTTCCTCAAGAACCGCGGCGCGGGT
GGCTTCCCGTTCCTCGCCGCCAACCTCAAGGTGAAGGACCCGGCGCTGGCGGGCGACCTGTCCATGCCGGCGTTCCAGAT
TTTCGAGCGCCGCGGCCTCAAGATTGGCGTGGTGGGCCTGGCGTCCGAGAAGACAGTCCGCACCGCCATGCCGGGCCGCG
CGGATGGCCTGGAAGTGACGGGCTATGAGGAGGCGCTCACCACCGCCATTCCGGAGGCCCGCAAGGCCGGCGCGGACGTG
GTCGTGGTGCTCGCCGACGAGTGCGTCACCGACCTGCAGCCCGCGGTGGCGAAGCACCCGGAGTGGAAGGTGGCGCTGGT
GGCCGGTGGCCGGTGCGCGCAGCCCGTCGAGCTGAAGGACGGCGCGACCAGCTTCGTGTCGCTGGACCGTGGCTTCGGCA
AGTACCTGCGCGCGCACGTCACCTTCGACCCGGCGAAGCCCGCGGGTGAGAAGCTGACCGGCCTGGATACCAAGGTCGTC
GAGGTGTCGGGCGGCGCGCCGGACGCGGAGACGGCGCAGCTGGTGGGCAAGTGGAAGACGCAGCTGGACGAGGTGCTGGG
CCAGCAGATTGGCTTCTCCAAGGCCGGCATCCCCCACTCGTCACCTCAGATGGCGAAGTGGGTGGCGGGCGCGGTGCGCA
ACGTGCTGGGCACGGACGCGGCCGTCCTCAACAGCGGCGGCATCCGCGGCGACCTGCCCGCCGGTCCGGTGACTCGCGGC
AGCATCTACTCGGTGATGCCGTTCGAGAACTCGCTCCTCGTCGTGAAGCTGAAGGGCGAGGACCTGGCCCGGCAGTTGGC
CAACCCGAACGCGCTCGTTTCCGGCTTCACGGCCGCGGGCAAGGGCAAGTTCAAGGACGCCAAGGGCAAGGCCCTGGACC
CGAACAAGGAGTACACGGTCGCCACGGTGGAGTACCTCTACTTCGGCGGTGACGGCTTCGAGTTCGAGAAGCTGGCCCCC
GAGCCCACCGAGACGGGCATGGCGTGGCAGACGCCGGTGGTGGACTGGACCAAGGACCAGGCGAGCAGCGACAAGAAGCC
GCTGGAGAAGCTGCTGAAGTAG

Upstream 100 bases:

>100_bases
TTGTGAACCTTGCCTTCGGGTGAGGAACCGCCGTGCCGCGTGTCGCTGTCTGCCACGTGTCTCAGCGTAGCACGAGCCGA
GTTGTGCTAAAGGCGCACCT

Downstream 100 bases:

>100_bases
TCCTCGCCGTCCTGCTTCTGTCGGACCCCTGAAGCGCCGGAGGAGGCCACCTGGGCCCTTCCGGCGCTTCGTCGTTTCAG
CGGGGCCAGGGGCTCACGGC

Product: 5'-nucleotidase family protein

Products: nucleoside 3'-phosphate

Alternate protein names: NA

Number of amino acids: Translated: 513; Mature: 512

Protein sequence:

>513_residues
MSANPLRPRPFRQPLSGVLVLALGVVAGCEKSNPTPPPAAAPEAKAPVAPSEVTLLVTGGAFGQLQPSEGKGGAAELLGR
WMADEKHCPGPVKEGQPTCADASTLALATGDHWNGPAISSFFLGTPTAEVMGRMGYAASALGNHELAFGKEAFLKNRGAG
GFPFLAANLKVKDPALAGDLSMPAFQIFERRGLKIGVVGLASEKTVRTAMPGRADGLEVTGYEEALTTAIPEARKAGADV
VVVLADECVTDLQPAVAKHPEWKVALVAGGRCAQPVELKDGATSFVSLDRGFGKYLRAHVTFDPAKPAGEKLTGLDTKVV
EVSGGAPDAETAQLVGKWKTQLDEVLGQQIGFSKAGIPHSSPQMAKWVAGAVRNVLGTDAAVLNSGGIRGDLPAGPVTRG
SIYSVMPFENSLLVVKLKGEDLARQLANPNALVSGFTAAGKGKFKDAKGKALDPNKEYTVATVEYLYFGGDGFEFEKLAP
EPTETGMAWQTPVVDWTKDQASSDKKPLEKLLK

Sequences:

>Translated_513_residues
MSANPLRPRPFRQPLSGVLVLALGVVAGCEKSNPTPPPAAAPEAKAPVAPSEVTLLVTGGAFGQLQPSEGKGGAAELLGR
WMADEKHCPGPVKEGQPTCADASTLALATGDHWNGPAISSFFLGTPTAEVMGRMGYAASALGNHELAFGKEAFLKNRGAG
GFPFLAANLKVKDPALAGDLSMPAFQIFERRGLKIGVVGLASEKTVRTAMPGRADGLEVTGYEEALTTAIPEARKAGADV
VVVLADECVTDLQPAVAKHPEWKVALVAGGRCAQPVELKDGATSFVSLDRGFGKYLRAHVTFDPAKPAGEKLTGLDTKVV
EVSGGAPDAETAQLVGKWKTQLDEVLGQQIGFSKAGIPHSSPQMAKWVAGAVRNVLGTDAAVLNSGGIRGDLPAGPVTRG
SIYSVMPFENSLLVVKLKGEDLARQLANPNALVSGFTAAGKGKFKDAKGKALDPNKEYTVATVEYLYFGGDGFEFEKLAP
EPTETGMAWQTPVVDWTKDQASSDKKPLEKLLK
>Mature_512_residues
SANPLRPRPFRQPLSGVLVLALGVVAGCEKSNPTPPPAAAPEAKAPVAPSEVTLLVTGGAFGQLQPSEGKGGAAELLGRW
MADEKHCPGPVKEGQPTCADASTLALATGDHWNGPAISSFFLGTPTAEVMGRMGYAASALGNHELAFGKEAFLKNRGAGG
FPFLAANLKVKDPALAGDLSMPAFQIFERRGLKIGVVGLASEKTVRTAMPGRADGLEVTGYEEALTTAIPEARKAGADVV
VVLADECVTDLQPAVAKHPEWKVALVAGGRCAQPVELKDGATSFVSLDRGFGKYLRAHVTFDPAKPAGEKLTGLDTKVVE
VSGGAPDAETAQLVGKWKTQLDEVLGQQIGFSKAGIPHSSPQMAKWVAGAVRNVLGTDAAVLNSGGIRGDLPAGPVTRGS
IYSVMPFENSLLVVKLKGEDLARQLANPNALVSGFTAAGKGKFKDAKGKALDPNKEYTVATVEYLYFGGDGFEFEKLAPE
PTETGMAWQTPVVDWTKDQASSDKKPLEKLLK

Specific function: Sugar-nonspecific endonuclease that yields nucleotide 3'-monophosphate products. No 5'-nucleotidase activity was detected, using 5'-AMP as the substrate, in the presence of diverse divalent metals and with various pH values [H]

COG id: COG0737

COG function: function code F; 5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases

Gene ontology:

Cell location: Periplasmic Protein [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 TNase-like domain [H]

Homologues:

None

Paralogues:

None

Copy number: 60 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). 20 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008334
- InterPro:   IPR006146
- InterPro:   IPR006179
- InterPro:   IPR019948
- InterPro:   IPR019931
- InterPro:   IPR004843
- InterPro:   IPR016027
- InterPro:   IPR004365
- InterPro:   IPR016071
- InterPro:   IPR006021 [H]

Pfam domain/function: PF02872 5_nucleotid_C; PF00746 Gram_pos_anchor; PF00149 Metallophos; PF00565 SNase; PF01336 tRNA_anti [H]

EC number: 3.1.4.16

Molecular weight: Translated: 53572; Mature: 53440

Theoretical pI: Translated: 7.10; Mature: 7.10

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSANPLRPRPFRQPLSGVLVLALGVVAGCEKSNPTPPPAAAPEAKAPVAPSEVTLLVTGG
CCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEECC
AFGQLQPSEGKGGAAELLGRWMADEKHCPGPVKEGQPTCADASTLALATGDHWNGPAISS
CCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCCCHHH
FFLGTPTAEVMGRMGYAASALGNHELAFGKEAFLKNRGAGGFPFLAANLKVKDPALAGDL
EECCCCHHHHHHHCCHHHHHCCCCCHHCCHHHHHHCCCCCCCCEEEECEEECCCCCCCCC
SMPAFQIFERRGLKIGVVGLASEKTVRTAMPGRADGLEVTGYEEALTTAIPEARKAGADV
CCHHHHHHHHCCCEEEEEEECCCCHHHHCCCCCCCCEEECCHHHHHHHHCCHHHHCCCCE
VVVLADECVTDLQPAVAKHPEWKVALVAGGRCAQPVELKDGATSFVSLDRGFGKYLRAHV
EEEECCHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHEEEEE
TFDPAKPAGEKLTGLDTKVVEVSGGAPDAETAQLVGKWKTQLDEVLGQQIGFSKAGIPHS
EECCCCCCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
SPQMAKWVAGAVRNVLGTDAAVLNSGGIRGDLPAGPVTRGSIYSVMPFENSLLVVKLKGE
CHHHHHHHHHHHHHHHCCCHHEECCCCCCCCCCCCCCCCCCEEEEECCCCCEEEEEECCH
DLARQLANPNALVSGFTAAGKGKFKDAKGKALDPNKEYTVATVEYLYFGGDGFEFEKLAP
HHHHHHCCCCCEEECCCCCCCCCCCCCCCCCCCCCCCEEEEEEEEEEECCCCCCHHHCCC
EPTETGMAWQTPVVDWTKDQASSDKKPLEKLLK
CCCCCCCEECCCCCCCCCCCCCCCHHHHHHHCC
>Mature Secondary Structure 
SANPLRPRPFRQPLSGVLVLALGVVAGCEKSNPTPPPAAAPEAKAPVAPSEVTLLVTGG
CCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEECC
AFGQLQPSEGKGGAAELLGRWMADEKHCPGPVKEGQPTCADASTLALATGDHWNGPAISS
CCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCCCHHH
FFLGTPTAEVMGRMGYAASALGNHELAFGKEAFLKNRGAGGFPFLAANLKVKDPALAGDL
EECCCCHHHHHHHCCHHHHHCCCCCHHCCHHHHHHCCCCCCCCEEEECEEECCCCCCCCC
SMPAFQIFERRGLKIGVVGLASEKTVRTAMPGRADGLEVTGYEEALTTAIPEARKAGADV
CCHHHHHHHHCCCEEEEEEECCCCHHHHCCCCCCCCEEECCHHHHHHHHCCHHHHCCCCE
VVVLADECVTDLQPAVAKHPEWKVALVAGGRCAQPVELKDGATSFVSLDRGFGKYLRAHV
EEEECCHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHEEEEE
TFDPAKPAGEKLTGLDTKVVEVSGGAPDAETAQLVGKWKTQLDEVLGQQIGFSKAGIPHS
EECCCCCCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
SPQMAKWVAGAVRNVLGTDAAVLNSGGIRGDLPAGPVTRGSIYSVMPFENSLLVVKLKGE
CHHHHHHHHHHHHHHHCCCHHEECCCCCCCCCCCCCCCCCCEEEEECCCCCEEEEEECCH
DLARQLANPNALVSGFTAAGKGKFKDAKGKALDPNKEYTVATVEYLYFGGDGFEFEKLAP
HHHHHHCCCCCEEECCCCCCCCCCCCCCCCCCCCCCCEEEEEEEEEEECCCCCCHHHCCC
EPTETGMAWQTPVVDWTKDQASSDKKPLEKLLK
CCCCCCCEECCCCCCCCCCCCCCCHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: nucleoside 2',3'-cyclic phosphate; H2O

Specific reaction: nucleoside 2',3'-cyclic phosphate + H2O = nucleoside 3'-phosphate

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8969498; 9384377 [H]