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The map label for this gene is pqqL [C]

Identifier: 108756807

GI number: 108756807

Start: 901171

End: 902625

Strand: Direct

Name: pqqL [C]

Synonym: MXAN_0791

Alternate gene names: 108756807

Gene position: 901171-902625 (Clockwise)

Preceding gene: 108757568

Following gene: 108758081

Centisome position: 9.86

GC content: 68.59

Gene sequence:

>1455_bases
GTGCGCCGCCGCCCGTTCCCGGGCGCTCTTCCGACAGGAGCACGGATGTTCCGTCAGTCGTTACTCTGGACCTCGTGTCT
GGCCCTGCTCGCCGGCCCCGTGGCCTGTGCGCAGACGCAGGGCGGCAAGCCGGTGGCGAAGTCCGCCGTGTCCGCCGCGC
CCAAGCTCGGCGCCGGCATCGAGTCCCGCACCCTCAAGAACGGGCTCAAGGTCATCGTCTGGCCCGACCACGACATTCCC
AATGTCGTCCTCTACAACTGGTTCCGCGTCGGCAGCCGGAACGAGTACCCCGGCATCACCGGCCTGTCCCACTTCTTCGA
GCACATGATGTTCAACGGTGCGAAGAAGTACGGCCCCGGTGAGTTCGACCGCGTCATGGAGGCCAACGGCGGCGCCAACA
ACGCCTTCACCTCCGAGGACGTCACCGTCTACATGGACTGGTTCCCGCGCTCCGCGCTCGACGTCATCTTCGACCTCGAG
GCCGACCGGCTCCAGCACCTGGCCATCGACCCCAAGGTCACCGAGTCCGAGCGCGGCGTCGTGTACTCGGAGCGCCGCTC
CGCCATCGACAACGACAACATGGGCGCCCTGATGGAGCAGGTGCAGGCCACCGCCTTCGTGGCGCACCCGTACCAGTTCC
CCGTCATCGGGTGGCCGTCCGACATCGAGTCGTGGCGCATCGAGGACCTCCAGCGCTACTACAAGACGTACTACGCGCCC
AACAACGCCACGCTCATCTTCACCGGCGCCGTGACGCCCGCGGAAATCTTCGCGCTCGCGGAGAAGTACCTGGAGCCCAT
CCCCTCCCAGCCCGCGCCGGAGCCCGTCCGCACCAAGGAGCCCGAGCAGCAGGGAGAGCGCCGCATCGTCGTGAAGAAGC
AGGCCCAGGCCCCGCTCATCCAACTGGCCTACCACGGCATCTCCGGCAAGGACGCGGACGTGGAAGCGCTCACGTTGCTC
CTGAGCATCCTCACCAACGGCGACTCCTCGCGGCTGCACCGCCGCCTCGTCGAGGAGGAGCGCGCCGCCCTCCGCGTCAA
CACCCACTTCAGCCCGGGCTTCGACCCCTCGCTCGTCTGGGTCTACGCGGACTTGCCGCCCGGTGCTGACGTCGCCAAGG
TGGAAGGCCTGCTCACTGAGGAGCTGGCCCGCGTCGTCAAGGACGGCGTCAGCGACGCCGAGCTCAAGAAGGCGCGCAAC
ATCACCCTGTCCCAGTTCTGGCGCAGCCTGGAGACCAACAACGGCCGCGGCCGCGCGCTGGGCGCCGCGGAGACGTTCCG
CGGTGACTACCGCCAGCTCTTCGACGCGCCCGACCGCTATGAGCGCGTGACGCGTGACGACGTCCGCAAGGTCGCCGCGC
GCATCTTCAACTCGCAGCGCCGCACCGTTGGTTGGCTCGTGCCCGCCGACGCGCAGGCCGCCACCCCCGACTCCCGCAAG
GAGGCCTCGCGATGA

Upstream 100 bases:

>100_bases
ATCAACTACTTCCAGGAAGTGCTCCGCGAAGTGCTCGGCGCCTGAGTCGCCGCGTCATCCGCCCTCCTGGTCAACCCAGG
AGGGTGGCAACTGGAATATC

Downstream 100 bases:

>100_bases
GCGCCCCCCTCTCCTGGAAGGCCGCGTTCACCACGCTGCTGCTGTCCTCCGTCCCCGCCGCGGCCCAGGGCTCCGCCGCT
GCTCCGAAGCCCGCCACGGC

Product: M16 family peptidase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 484; Mature: 484

Protein sequence:

>484_residues
MRRRPFPGALPTGARMFRQSLLWTSCLALLAGPVACAQTQGGKPVAKSAVSAAPKLGAGIESRTLKNGLKVIVWPDHDIP
NVVLYNWFRVGSRNEYPGITGLSHFFEHMMFNGAKKYGPGEFDRVMEANGGANNAFTSEDVTVYMDWFPRSALDVIFDLE
ADRLQHLAIDPKVTESERGVVYSERRSAIDNDNMGALMEQVQATAFVAHPYQFPVIGWPSDIESWRIEDLQRYYKTYYAP
NNATLIFTGAVTPAEIFALAEKYLEPIPSQPAPEPVRTKEPEQQGERRIVVKKQAQAPLIQLAYHGISGKDADVEALTLL
LSILTNGDSSRLHRRLVEEERAALRVNTHFSPGFDPSLVWVYADLPPGADVAKVEGLLTEELARVVKDGVSDAELKKARN
ITLSQFWRSLETNNGRGRALGAAETFRGDYRQLFDAPDRYERVTRDDVRKVAARIFNSQRRTVGWLVPADAQAATPDSRK
EASR

Sequences:

>Translated_484_residues
MRRRPFPGALPTGARMFRQSLLWTSCLALLAGPVACAQTQGGKPVAKSAVSAAPKLGAGIESRTLKNGLKVIVWPDHDIP
NVVLYNWFRVGSRNEYPGITGLSHFFEHMMFNGAKKYGPGEFDRVMEANGGANNAFTSEDVTVYMDWFPRSALDVIFDLE
ADRLQHLAIDPKVTESERGVVYSERRSAIDNDNMGALMEQVQATAFVAHPYQFPVIGWPSDIESWRIEDLQRYYKTYYAP
NNATLIFTGAVTPAEIFALAEKYLEPIPSQPAPEPVRTKEPEQQGERRIVVKKQAQAPLIQLAYHGISGKDADVEALTLL
LSILTNGDSSRLHRRLVEEERAALRVNTHFSPGFDPSLVWVYADLPPGADVAKVEGLLTEELARVVKDGVSDAELKKARN
ITLSQFWRSLETNNGRGRALGAAETFRGDYRQLFDAPDRYERVTRDDVRKVAARIFNSQRRTVGWLVPADAQAATPDSRK
EASR
>Mature_484_residues
MRRRPFPGALPTGARMFRQSLLWTSCLALLAGPVACAQTQGGKPVAKSAVSAAPKLGAGIESRTLKNGLKVIVWPDHDIP
NVVLYNWFRVGSRNEYPGITGLSHFFEHMMFNGAKKYGPGEFDRVMEANGGANNAFTSEDVTVYMDWFPRSALDVIFDLE
ADRLQHLAIDPKVTESERGVVYSERRSAIDNDNMGALMEQVQATAFVAHPYQFPVIGWPSDIESWRIEDLQRYYKTYYAP
NNATLIFTGAVTPAEIFALAEKYLEPIPSQPAPEPVRTKEPEQQGERRIVVKKQAQAPLIQLAYHGISGKDADVEALTLL
LSILTNGDSSRLHRRLVEEERAALRVNTHFSPGFDPSLVWVYADLPPGADVAKVEGLLTEELARVVKDGVSDAELKKARN
ITLSQFWRSLETNNGRGRALGAAETFRGDYRQLFDAPDRYERVTRDDVRKVAARIFNSQRRTVGWLVPADAQAATPDSRK
EASR

Specific function: Unknown

COG id: COG0612

COG function: function code R; Predicted Zn-dependent peptidases

Gene ontology:

Cell location: Cell membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M16 family [H]

Homologues:

Organism=Homo sapiens, GI94538354, Length=356, Percent_Identity=23.0337078651685, Blast_Score=79, Evalue=7e-15,
Organism=Homo sapiens, GI46593007, Length=217, Percent_Identity=27.6497695852535, Blast_Score=79, Evalue=1e-14,
Organism=Homo sapiens, GI155969707, Length=236, Percent_Identity=25.8474576271186, Blast_Score=69, Evalue=1e-11,
Organism=Escherichia coli, GI1787770, Length=220, Percent_Identity=28.1818181818182, Blast_Score=77, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI17553678, Length=426, Percent_Identity=23.0046948356808, Blast_Score=81, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI71999683, Length=202, Percent_Identity=28.7128712871287, Blast_Score=79, Evalue=6e-15,
Organism=Saccharomyces cerevisiae, GI6323192, Length=405, Percent_Identity=21.4814814814815, Blast_Score=72, Evalue=2e-13,
Organism=Drosophila melanogaster, GI21357875, Length=212, Percent_Identity=25.9433962264151, Blast_Score=76, Evalue=5e-14,
Organism=Drosophila melanogaster, GI24646943, Length=212, Percent_Identity=25.9433962264151, Blast_Score=76, Evalue=5e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011249
- InterPro:   IPR011237
- InterPro:   IPR011765
- InterPro:   IPR001431
- InterPro:   IPR007863 [H]

Pfam domain/function: PF00675 Peptidase_M16; PF05193 Peptidase_M16_C [H]

EC number: 3.4.99.- [C]

Molecular weight: Translated: 53931; Mature: 53931

Theoretical pI: Translated: 7.71; Mature: 7.71

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRRRPFPGALPTGARMFRQSLLWTSCLALLAGPVACAQTQGGKPVAKSAVSAAPKLGAGI
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHCCCCCCHHHHHHHHHCCHHCCCC
ESRTLKNGLKVIVWPDHDIPNVVLYNWFRVGSRNEYPGITGLSHFFEHMMFNGAKKYGPG
HHHHHHCCCEEEEECCCCCCCHHHHHEEECCCCCCCCCCHHHHHHHHHHHHCCCCCCCCC
EFDRVMEANGGANNAFTSEDVTVYMDWFPRSALDVIFDLEADRLQHLAIDPKVTESERGV
HHHHHHHCCCCCCCCCCCCCEEEEEECCCCHHHHHHHCCCHHHHHHHCCCCCCCCCCCCC
VYSERRSAIDNDNMGALMEQVQATAFVAHPYQFPVIGWPSDIESWRIEDLQRYYKTYYAP
EEHHHHHCCCCCCHHHHHHHHHHHHEEECCEECCEECCCCCHHHHHHHHHHHHHHHHCCC
NNATLIFTGAVTPAEIFALAEKYLEPIPSQPAPEPVRTKEPEQQGERRIVVKKQAQAPLI
CCCEEEEECCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHCCCEEEEECCCCCCEE
QLAYHGISGKDADVEALTLLLSILTNGDSSRLHRRLVEEERAALRVNTHFSPGFDPSLVW
HHHHCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHEEEEECCCCCCCCCCEEE
VYADLPPGADVAKVEGLLTEELARVVKDGVSDAELKKARNITLSQFWRSLETNNGRGRAL
EEECCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCHHHHHHHHHCCCCCCCEE
GAAETFRGDYRQLFDAPDRYERVTRDDVRKVAARIFNSQRRTVGWLVPADAQAATPDSRK
CHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCHH
EASR
HCCC
>Mature Secondary Structure
MRRRPFPGALPTGARMFRQSLLWTSCLALLAGPVACAQTQGGKPVAKSAVSAAPKLGAGI
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHCCCCCCHHHHHHHHHCCHHCCCC
ESRTLKNGLKVIVWPDHDIPNVVLYNWFRVGSRNEYPGITGLSHFFEHMMFNGAKKYGPG
HHHHHHCCCEEEEECCCCCCCHHHHHEEECCCCCCCCCCHHHHHHHHHHHHCCCCCCCCC
EFDRVMEANGGANNAFTSEDVTVYMDWFPRSALDVIFDLEADRLQHLAIDPKVTESERGV
HHHHHHHCCCCCCCCCCCCCEEEEEECCCCHHHHHHHCCCHHHHHHHCCCCCCCCCCCCC
VYSERRSAIDNDNMGALMEQVQATAFVAHPYQFPVIGWPSDIESWRIEDLQRYYKTYYAP
EEHHHHHCCCCCCHHHHHHHHHHHHEEECCEECCEECCCCCHHHHHHHHHHHHHHHHCCC
NNATLIFTGAVTPAEIFALAEKYLEPIPSQPAPEPVRTKEPEQQGERRIVVKKQAQAPLI
CCCEEEEECCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHCCCEEEEECCCCCCEE
QLAYHGISGKDADVEALTLLLSILTNGDSSRLHRRLVEEERAALRVNTHFSPGFDPSLVW
HHHHCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHEEEEECCCCCCCCCCEEE
VYADLPPGADVAKVEGLLTEELARVVKDGVSDAELKKARNITLSQFWRSLETNNGRGRAL
EEECCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCHHHHHHHHHCCCCCCCEE
GAAETFRGDYRQLFDAPDRYERVTRDDVRKVAARIFNSQRRTVGWLVPADAQAATPDSRK
CHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCHH
EASR
HCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: Zn [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases); Endopeptidases of unknown catalytic mechanism [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9163424 [H]