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The map label for this gene is ribE [H]

Identifier: 108563948

GI number: 108563948

Start: 1585990

End: 1586610

Strand: Direct

Name: ribE [H]

Synonym: HPAG1_1523

Alternate gene names: 108563948

Gene position: 1585990-1586610 (Clockwise)

Preceding gene: 108563938

Following gene: 108563949

Centisome position: 99.35

GC content: 39.94

Gene sequence:

>621_bases
ATGTTCAGCGGTCTAATCCATCAAATAGCTAAAGTGAAAAGTTTCCAAAACAATATTTTAAGCGTAGAGAGCGATCTCAA
TCCCAAGCTTGGCGATAGCATTGCGATTAATGGGGCATGTTTGACCGCCATAGAAAGTTCAAAAACGCATTTTAGTGTGG
AATTGAGCCAAAAAACCCAAAACAGCGTAGCGTTAGAAAATTACAAGGATTTAGTCCATATTGAGCCAGCTCTAAAAGCC
GATGCGAGTTTGGACGGGCATTTTGTGCAAGGGCATATTGACGCTATCGGGGTCATTGAAAAAATCATTCACAACGCTAA
TCAAGTGGATTTTTTCATCAGCGCTTCTGAAGAAACGCTTTTATTGTGTGTTGAGCAAGGCTCTATCGCCATTGATGGGG
TGAGTTTGACTTTAAGCAAGGTAGAAGAAAAGGGGTTTTGGCTAACGATTATCCCTTACACTTTAGAAAACACCCTTTTT
AAGACTTATAAACTCAAACGGCGCGTGAATATTGAAACGGACATGCTGGTTCGCAGCGTTGCATCTATTTTGAAAAAAAC
AAAAGGGTTTGAAAAAAATTTCTCTTGGAATGACGCGGATTCTTTGACTTTAGGGTATTAG

Upstream 100 bases:

>100_bases
AAATGGCAATGCGTATCAATAAACATGCTTTTATCCTATGGTTTTATTTAATATGTTACAATATTTAAGCATTTTAACAT
AAGGAAAATAATCATTAACG

Downstream 100 bases:

>100_bases
ATGAATAAAACCATAAAAGCCGCCGCTCTAGCCTATAACATGGGGCAAGATCATGCCCCAAAAGTGATCGCAAGCGGGGT
GGGCGAAGTGGCTAAAAGGA

Product: riboflavin synthase subunit alpha

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 206; Mature: 206

Protein sequence:

>206_residues
MFSGLIHQIAKVKSFQNNILSVESDLNPKLGDSIAINGACLTAIESSKTHFSVELSQKTQNSVALENYKDLVHIEPALKA
DASLDGHFVQGHIDAIGVIEKIIHNANQVDFFISASEETLLLCVEQGSIAIDGVSLTLSKVEEKGFWLTIIPYTLENTLF
KTYKLKRRVNIETDMLVRSVASILKKTKGFEKNFSWNDADSLTLGY

Sequences:

>Translated_206_residues
MFSGLIHQIAKVKSFQNNILSVESDLNPKLGDSIAINGACLTAIESSKTHFSVELSQKTQNSVALENYKDLVHIEPALKA
DASLDGHFVQGHIDAIGVIEKIIHNANQVDFFISASEETLLLCVEQGSIAIDGVSLTLSKVEEKGFWLTIIPYTLENTLF
KTYKLKRRVNIETDMLVRSVASILKKTKGFEKNFSWNDADSLTLGY
>Mature_206_residues
MFSGLIHQIAKVKSFQNNILSVESDLNPKLGDSIAINGACLTAIESSKTHFSVELSQKTQNSVALENYKDLVHIEPALKA
DASLDGHFVQGHIDAIGVIEKIIHNANQVDFFISASEETLLLCVEQGSIAIDGVSLTLSKVEEKGFWLTIIPYTLENTLF
KTYKLKRRVNIETDMLVRSVASILKKTKGFEKNFSWNDADSLTLGY

Specific function: Riboflavin synthase is a bifunctional enzyme complex catalyzing the formation of riboflavin from 5-amino-6-(1'-D)- ribityl-amino-2,4(1H,3H)-pyrimidinedione and L-3,4-dihydrohy-2- butanone-4-phosphate via 6,7-dimethyl-8-lumazine. The alpha subunit catalyze

COG id: COG0307

COG function: function code H; Riboflavin synthase alpha chain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 lumazine-binding repeats [H]

Homologues:

Organism=Escherichia coli, GI1787952, Length=204, Percent_Identity=30.8823529411765, Blast_Score=92, Evalue=4e-20,
Organism=Saccharomyces cerevisiae, GI6319733, Length=153, Percent_Identity=35.9477124183007, Blast_Score=87, Evalue=1e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001783
- InterPro:   IPR017938 [H]

Pfam domain/function: PF00677 Lum_binding [H]

EC number: =2.5.1.9 [H]

Molecular weight: Translated: 22803; Mature: 22803

Theoretical pI: Translated: 5.94; Mature: 5.94

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFSGLIHQIAKVKSFQNNILSVESDLNPKLGDSIAINGACLTAIESSKTHFSVELSQKTQ
CCHHHHHHHHHHHHHHCCEEEECCCCCCCCCCEEEECCEEEEEEECCCCEEEEEECCCCC
NSVALENYKDLVHIEPALKADASLDGHFVQGHIDAIGVIEKIIHNANQVDFFISASEETL
CCEEHHCCCCEEEECCHHCCCCCCCCEEEECHHHHHHHHHHHHCCCCCEEEEEECCCCEE
LLCVEQGSIAIDGVSLTLSKVEEKGFWLTIIPYTLENTLFKTYKLKRRVNIETDMLVRSV
EEEEECCCEEEECCEEEEEHHHCCCCEEEEECHHHHHHHHHHHHHHHHCCCHHHHHHHHH
ASILKKTKGFEKNFSWNDADSLTLGY
HHHHHHHCCCCCCCCCCCCCCEEECC
>Mature Secondary Structure
MFSGLIHQIAKVKSFQNNILSVESDLNPKLGDSIAINGACLTAIESSKTHFSVELSQKTQ
CCHHHHHHHHHHHHHHCCEEEECCCCCCCCCCEEEECCEEEEEEECCCCEEEEEECCCCC
NSVALENYKDLVHIEPALKADASLDGHFVQGHIDAIGVIEKIIHNANQVDFFISASEETL
CCEEHHCCCCEEEECCHHCCCCCCCCEEEECHHHHHHHHHHHHCCCCCEEEEEECCCCEE
LLCVEQGSIAIDGVSLTLSKVEEKGFWLTIIPYTLENTLFKTYKLKRRVNIETDMLVRSV
EEEEECCCEEEECCEEEEEHHHCCCCEEEEECHHHHHHHHHHHHHHHHCCCHHHHHHHHH
ASILKKTKGFEKNFSWNDADSLTLGY
HHHHHHHCCCCCCCCCCCCCCEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9537320 [H]