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The map label for this gene is yabD [H]

Identifier: 108563947

GI number: 108563947

Start: 1585151

End: 1585915

Strand: Reverse

Name: yabD [H]

Synonym: HPAG1_1522

Alternate gene names: 108563947

Gene position: 1585915-1585151 (Counterclockwise)

Preceding gene: 108563952

Following gene: 108563946

Centisome position: 99.35

GC content: 39.35

Gene sequence:

>765_bases
ATGTTTATTGATACGCATTGCCATTTGGATCATAAGGATTATGAAAATGATTTAGAAGAAGTGCTAAAAGAAAGCCTAGA
AAAAGGCGTTACTCAATGCGTGATTCCGGGCGCGGACATGAAAGATTTGAACAGAGCAATAGAGATTAGCGAAAAATTTG
AAGGCGTGTTTTTTGCTATAGGCGCTCACCCCTATGATGTGGAAAGCTTTGATGAAAGCTTGTTTGAAAAATTTGTCAGT
CATCAAAAATGCGTGGCGATAGGCGAATGCGGACTGGATTACTACCGCTTGCCTGAATTGAGCGAAAGAGAAAATTATAA
AAGCAAACAAAAAGAAATTTTTACCAAACAGATTGAGTTTTCTATCCAGCACAACAAGCCCTTGATTATCCATATTAGAG
AGGCGAGTTTTGATAGTTTGAATCTTTTAAAAAGCTATCCTAAAGCTTTTGGGGTGTTGCATTGCTTTAACGCTGATGGC
ATGCTTTTGGAATTGAGCGATCGTTTTTACTACGGGATAGGAGGGGTTAGCACTTTTAAAAACGCTAAAAGACTGGTAGA
GATCCTCCCTAAAATCCCTAAAAACAGGCTTCTTTTAGAAACGGATTCGCCTTATTTGACCCCACACCCTTTTAGAGGCA
CCAGAAATAGCCCTACTTATATCCCTTTAATCGCTCAAAAAATTGCCGAAATCATCAACATAGAGACTGAAGAACTCGCT
TCTTTAAGCACGCATAACGCTCAAACGCTCTTTAGTTTCCCCTGA

Upstream 100 bases:

>100_bases
ATTTGATGGATTAGACCGCTGAACATCGTTAATGATTATTTTCCTTATGTTAAAATGCTTAAATATTGTAACATATTAAA
TAAAACCATAGGATAAAAGC

Downstream 100 bases:

>100_bases
AAATAAGGCTGTGTTAGAAAGCGTTATTCAAGTTTAGTTATAATCAAAGCTATTTTAAAAGCTGGATAGCTGTAGTTATT
AGGATGCGATGTCAAAAAGA

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 254; Mature: 254

Protein sequence:

>254_residues
MFIDTHCHLDHKDYENDLEEVLKESLEKGVTQCVIPGADMKDLNRAIEISEKFEGVFFAIGAHPYDVESFDESLFEKFVS
HQKCVAIGECGLDYYRLPELSERENYKSKQKEIFTKQIEFSIQHNKPLIIHIREASFDSLNLLKSYPKAFGVLHCFNADG
MLLELSDRFYYGIGGVSTFKNAKRLVEILPKIPKNRLLLETDSPYLTPHPFRGTRNSPTYIPLIAQKIAEIINIETEELA
SLSTHNAQTLFSFP

Sequences:

>Translated_254_residues
MFIDTHCHLDHKDYENDLEEVLKESLEKGVTQCVIPGADMKDLNRAIEISEKFEGVFFAIGAHPYDVESFDESLFEKFVS
HQKCVAIGECGLDYYRLPELSERENYKSKQKEIFTKQIEFSIQHNKPLIIHIREASFDSLNLLKSYPKAFGVLHCFNADG
MLLELSDRFYYGIGGVSTFKNAKRLVEILPKIPKNRLLLETDSPYLTPHPFRGTRNSPTYIPLIAQKIAEIINIETEELA
SLSTHNAQTLFSFP
>Mature_254_residues
MFIDTHCHLDHKDYENDLEEVLKESLEKGVTQCVIPGADMKDLNRAIEISEKFEGVFFAIGAHPYDVESFDESLFEKFVS
HQKCVAIGECGLDYYRLPELSERENYKSKQKEIFTKQIEFSIQHNKPLIIHIREASFDSLNLLKSYPKAFGVLHCFNADG
MLLELSDRFYYGIGGVSTFKNAKRLVEILPKIPKNRLLLETDSPYLTPHPFRGTRNSPTYIPLIAQKIAEIINIETEELA
SLSTHNAQTLFSFP

Specific function: Unknown

COG id: COG0084

COG function: function code L; Mg-dependent DNase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tatD DNase family [H]

Homologues:

Organism=Homo sapiens, GI110349730, Length=264, Percent_Identity=26.8939393939394, Blast_Score=100, Evalue=1e-21,
Organism=Homo sapiens, GI110349734, Length=266, Percent_Identity=27.4436090225564, Blast_Score=100, Evalue=1e-21,
Organism=Homo sapiens, GI226061853, Length=274, Percent_Identity=27.007299270073, Blast_Score=99, Evalue=3e-21,
Organism=Homo sapiens, GI226061614, Length=251, Percent_Identity=26.2948207171315, Blast_Score=94, Evalue=9e-20,
Organism=Homo sapiens, GI225903424, Length=261, Percent_Identity=27.9693486590038, Blast_Score=91, Evalue=1e-18,
Organism=Homo sapiens, GI14042943, Length=279, Percent_Identity=27.5985663082437, Blast_Score=90, Evalue=2e-18,
Organism=Homo sapiens, GI226061595, Length=231, Percent_Identity=25.5411255411255, Blast_Score=77, Evalue=1e-14,
Organism=Homo sapiens, GI225903439, Length=259, Percent_Identity=27.4131274131274, Blast_Score=76, Evalue=2e-14,
Organism=Escherichia coli, GI1787342, Length=271, Percent_Identity=37.2693726937269, Blast_Score=163, Evalue=1e-41,
Organism=Escherichia coli, GI48994985, Length=268, Percent_Identity=29.4776119402985, Blast_Score=119, Evalue=1e-28,
Organism=Escherichia coli, GI87082439, Length=266, Percent_Identity=28.1954887218045, Blast_Score=118, Evalue=4e-28,
Organism=Caenorhabditis elegans, GI17559024, Length=290, Percent_Identity=27.9310344827586, Blast_Score=122, Evalue=2e-28,
Organism=Caenorhabditis elegans, GI71980746, Length=262, Percent_Identity=28.6259541984733, Blast_Score=102, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI17565396, Length=303, Percent_Identity=27.0627062706271, Blast_Score=74, Evalue=5e-14,
Organism=Caenorhabditis elegans, GI17543026, Length=193, Percent_Identity=28.4974093264249, Blast_Score=73, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24648690, Length=290, Percent_Identity=30.3448275862069, Blast_Score=117, Evalue=7e-27,
Organism=Drosophila melanogaster, GI24586117, Length=291, Percent_Identity=27.1477663230241, Blast_Score=99, Evalue=3e-21,
Organism=Drosophila melanogaster, GI221330018, Length=243, Percent_Identity=28.8065843621399, Blast_Score=99, Evalue=3e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015992
- InterPro:   IPR001130
- InterPro:   IPR018228
- InterPro:   IPR012278
- InterPro:   IPR015991 [H]

Pfam domain/function: PF01026 TatD_DNase [H]

EC number: 3.1.21.-

Molecular weight: Translated: 29124; Mature: 29124

Theoretical pI: Translated: 5.58; Mature: 5.58

Prosite motif: PS01137 TATD_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFIDTHCHLDHKDYENDLEEVLKESLEKGVTQCVIPGADMKDLNRAIEISEKFEGVFFAI
CEECCEECCCCHHHHHHHHHHHHHHHHCCCCEEECCCCCHHHHHHHHHHHHHCCEEEEEE
GAHPYDVESFDESLFEKFVSHQKCVAIGECGLDYYRLPELSERENYKSKQKEIFTKQIEF
CCCCCCHHHHHHHHHHHHHCCCCEEEECCCCCCHHCCCCCCHHHHHHHHHHHHHHHHHEE
SIQHNKPLIIHIREASFDSLNLLKSYPKAFGVLHCFNADGMLLELSDRFYYGIGGVSTFK
EEECCCCEEEEEECCCCCHHHHHHHHHHHHCEEEEECCCCEEEEECCCEEECCCCHHHHH
NAKRLVEILPKIPKNRLLLETDSPYLTPHPFRGTRNSPTYIPLIAQKIAEIINIETEELA
HHHHHHHHHHCCCCCCEEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCHHHHH
SLSTHNAQTLFSFP
HHHCCCCCEEECCC
>Mature Secondary Structure
MFIDTHCHLDHKDYENDLEEVLKESLEKGVTQCVIPGADMKDLNRAIEISEKFEGVFFAI
CEECCEECCCCHHHHHHHHHHHHHHHHCCCCEEECCCCCHHHHHHHHHHHHHCCEEEEEE
GAHPYDVESFDESLFEKFVSHQKCVAIGECGLDYYRLPELSERENYKSKQKEIFTKQIEF
CCCCCCHHHHHHHHHHHHHCCCCEEEECCCCCCHHCCCCCCHHHHHHHHHHHHHHHHHEE
SIQHNKPLIIHIREASFDSLNLLKSYPKAFGVLHCFNADGMLLELSDRFYYGIGGVSTFK
EEECCCCEEEEEECCCCCHHHHHHHHHHHHCEEEEECCCCEEEEECCCEEECCCCHHHHH
NAKRLVEILPKIPKNRLLLETDSPYLTPHPFRGTRNSPTYIPLIAQKIAEIINIETEELA
HHHHHHHHHHCCCCCCEEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCHHHHH
SLSTHNAQTLFSFP
HHHCCCCCEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377 [H]