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The map label for this gene is rpe [H]

Identifier: 108563907

GI number: 108563907

Start: 1543487

End: 1544140

Strand: Reverse

Name: rpe [H]

Synonym: HPAG1_1482

Alternate gene names: 108563907

Gene position: 1544140-1543487 (Counterclockwise)

Preceding gene: 108563912

Following gene: 108563906

Centisome position: 96.73

GC content: 42.05

Gene sequence:

>654_bases
TTGAAAGTAGCTCCGAGCCTTTTGAGCGCTGATTTTATGCATTTAGCCAAAGAGATAGAGAGCGTGAGTAACGCTGATTT
TTTGCATGTGGATGTGATGGATGGGCATTATGTGCCTAATTTAACCATGGGGCCTGTGGTTTTAGAGAATGTTACTCAAA
TGAGCCAAGTGCCTTTAGATGTGCATTTAATGGTAGAAAATGCGAGCTTTTTTGTGGGATTATTCGCTCCTTTAAAACCG
CAAATCATCAGCATTCATGCAGAAAATGAAAAACACCCCCATAGGGTGTTGCAACTCATTAAACATTCAGGCATCACGCC
AGGTGTTGTTCTAAACCCTCACACGCATGAAGAAAGCATTAAATACTTGCTAGAAAGCGTGGGGCTAGTGCTTTTAATGA
GCGTGAATCCGGGCTTTGGCGGGCAGAAGTTTTTAGATCTGGTGCTAGAAAAGTGTTTGAAAGTTAAAGAATTGATCAAA
CGCTACAACCCGAGCTGCCTTTTAGAAGTGGATGGGGGCGTGAATGATAAAAATATCTTTGAACTCCAACAAGCGGGCGT
GGATGTGGTGGTTTCAGGGAGTTATATTTTTAAATCTAAAGATCGTAAGCTGGCTATTGAAGGCTTACAGAATGTCAGAC
AGCCTCTTGCATAA

Upstream 100 bases:

>100_bases
ATGCTTGCCTTTAAAATGTTTGTAATCCATAAAAACCCTTTTATGATTTGATTAAAGATGCTAATATTTTACTTGAAAAC
ATTGGAAATAGGGAAGTATT

Downstream 100 bases:

>100_bases
AGACATTCAAGCCCTAATCGCTCGCTTAAAGCACCAGGATTTAAGCTTGGGCATGCTAGAAAAATCGCTCTCTCGCCTTA
TTTATGATGAAATCAATTTG

Product: ribulose-phosphate 3-epimerase

Products: NA

Alternate protein names: Pentose-5-phosphate 3-epimerase; PPE; R5P3E [H]

Number of amino acids: Translated: 217; Mature: 217

Protein sequence:

>217_residues
MKVAPSLLSADFMHLAKEIESVSNADFLHVDVMDGHYVPNLTMGPVVLENVTQMSQVPLDVHLMVENASFFVGLFAPLKP
QIISIHAENEKHPHRVLQLIKHSGITPGVVLNPHTHEESIKYLLESVGLVLLMSVNPGFGGQKFLDLVLEKCLKVKELIK
RYNPSCLLEVDGGVNDKNIFELQQAGVDVVVSGSYIFKSKDRKLAIEGLQNVRQPLA

Sequences:

>Translated_217_residues
MKVAPSLLSADFMHLAKEIESVSNADFLHVDVMDGHYVPNLTMGPVVLENVTQMSQVPLDVHLMVENASFFVGLFAPLKP
QIISIHAENEKHPHRVLQLIKHSGITPGVVLNPHTHEESIKYLLESVGLVLLMSVNPGFGGQKFLDLVLEKCLKVKELIK
RYNPSCLLEVDGGVNDKNIFELQQAGVDVVVSGSYIFKSKDRKLAIEGLQNVRQPLA
>Mature_217_residues
MKVAPSLLSADFMHLAKEIESVSNADFLHVDVMDGHYVPNLTMGPVVLENVTQMSQVPLDVHLMVENASFFVGLFAPLKP
QIISIHAENEKHPHRVLQLIKHSGITPGVVLNPHTHEESIKYLLESVGLVLLMSVNPGFGGQKFLDLVLEKCLKVKELIK
RYNPSCLLEVDGGVNDKNIFELQQAGVDVVVSGSYIFKSKDRKLAIEGLQNVRQPLA

Specific function: Unknown

COG id: COG0036

COG function: function code G; Pentose-5-phosphate-3-epimerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ribulose-phosphate 3-epimerase family [H]

Homologues:

Organism=Homo sapiens, GI40385883, Length=215, Percent_Identity=35.8139534883721, Blast_Score=134, Evalue=5e-32,
Organism=Homo sapiens, GI219879828, Length=215, Percent_Identity=33.953488372093, Blast_Score=127, Evalue=5e-30,
Organism=Homo sapiens, GI24307923, Length=170, Percent_Identity=27.6470588235294, Blast_Score=75, Evalue=3e-14,
Organism=Escherichia coli, GI1789788, Length=212, Percent_Identity=43.8679245283019, Blast_Score=172, Evalue=1e-44,
Organism=Escherichia coli, GI1790523, Length=196, Percent_Identity=34.6938775510204, Blast_Score=137, Evalue=5e-34,
Organism=Escherichia coli, GI1790754, Length=208, Percent_Identity=30.2884615384615, Blast_Score=107, Evalue=6e-25,
Organism=Caenorhabditis elegans, GI17552948, Length=217, Percent_Identity=37.3271889400922, Blast_Score=129, Evalue=8e-31,
Organism=Saccharomyces cerevisiae, GI6322341, Length=214, Percent_Identity=34.5794392523364, Blast_Score=130, Evalue=2e-31,
Organism=Drosophila melanogaster, GI24586301, Length=214, Percent_Identity=35.0467289719626, Blast_Score=125, Evalue=2e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR000056
- InterPro:   IPR011060 [H]

Pfam domain/function: PF00834 Ribul_P_3_epim [H]

EC number: =5.1.3.1 [H]

Molecular weight: Translated: 23994; Mature: 23994

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: PS01085 RIBUL_P_3_EPIMER_1 ; PS01086 RIBUL_P_3_EPIMER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKVAPSLLSADFMHLAKEIESVSNADFLHVDVMDGHYVPNLTMGPVVLENVTQMSQVPLD
CCCCHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCCCCCHHHHHHHHHHHHCCCE
VHLMVENASFFVGLFAPLKPQIISIHAENEKHPHRVLQLIKHSGITPGVVLNPHTHEESI
EEEEEECCCEEEEECCCCCCEEEEEEECCCCCHHHHHHHHHHCCCCCCEEECCCCCHHHH
KYLLESVGLVLLMSVNPGFGGQKFLDLVLEKCLKVKELIKRYNPSCLLEVDGGVNDKNIF
HHHHHHCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCHHHH
ELQQAGVDVVVSGSYIFKSKDRKLAIEGLQNVRQPLA
HHHHCCEEEEEECCEEEECCCCCHHHHHHHHHHHCCC
>Mature Secondary Structure
MKVAPSLLSADFMHLAKEIESVSNADFLHVDVMDGHYVPNLTMGPVVLENVTQMSQVPLD
CCCCHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCCCCCHHHHHHHHHHHHCCCE
VHLMVENASFFVGLFAPLKPQIISIHAENEKHPHRVLQLIKHSGITPGVVLNPHTHEESI
EEEEEECCCEEEEECCCCCCEEEEEEECCCCCHHHHHHHHHHCCCCCCEEECCCCCHHHH
KYLLESVGLVLLMSVNPGFGGQKFLDLVLEKCLKVKELIKRYNPSCLLEVDGGVNDKNIF
HHHHHHCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCHHHH
ELQQAGVDVVVSGSYIFKSKDRKLAIEGLQNVRQPLA
HHHHCCEEEEEECCEEEECCCCCHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9923682 [H]