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The map label for this gene is 108563887

Identifier: 108563887

GI number: 108563887

Start: 1520168

End: 1521295

Strand: Reverse

Name: 108563887

Synonym: HPAG1_1462

Alternate gene names: NA

Gene position: 1521295-1520168 (Counterclockwise)

Preceding gene: 108563888

Following gene: 108563879

Centisome position: 95.3

GC content: 31.47

Gene sequence:

>1128_bases
ATGGACGCATTAATGCTGCCCTTAAATTGGCAAAGAGTGAGACTTGGGGATATTGGCAAACCATGCATGTGTAAAAGAGT
TATGAAACATCAAACAACACGATATGGTGAAATTCCATTTTATAAAATAGGCACATTTGGCAACACCGCTGATGCCTTTA
TTTCAAAAAAGCTATTTTTAGAATACAAAACAAAATATTCTTTTCCAAAAAAAGGCGATATTTTAATTTCTGCTTCCGGA
ACTATTGGTAAGGCAGTCATTTATGATGGAAAACCCGCTTATTTTCAAGACTCAAATATTGTTTGGATTGACAACGATGA
AACATTAGTAAAAAATGATTTTTTATTTTATGCTTATTCTAATGTTAAATGGAATACAGAGCATACAACTATCTTAAGAC
TTTATAATGATAATTTTAGAAATACTTTAATCCCCCTACCCCCTCTAAACGAACAAATCGCTATCGCTAACATTTTAAGC
GATTTGGATCATTATCTTTATTCTTTAGACGCCCTCATTCTTAAAAAAGAAAGCGTTAAAAAAGCTTTAAGCTTTGAACT
ATTGAGCCAAAGAAAACGCTTGAAAGGCTTCAATCAAGCTTGGCAAAGAGTAAGGCTTGGGGATATATGCGAAATCACAA
CCGGTTCATTAGATGCAAATGAAATGGTTCATTATGGAAAATATAGATTTTATACATGTGCAAAAGAATATTATTTTATA
GATAAATACGCTTTTGACACAGAAGCAATTTTAATTTCTGGAAATGGTGCGTATGTAGGGTATGTGCATTACTATAAGGG
CAAATTTAACGCCTATCAAAGAACCTATGTGTTGGATAATTTTAGCGAACATATTATATTTATAAAATATTTTTTAACAA
TGTTTTTGCAATCTCATATTCAAACAAATAGAAATGAAGGTAATACCCCTTATATCGTAACGGCAACTTTAAAAGATTTT
GAAATCCTTTTACCCCCTCTAAACGAACAAATCGCTATCGCTAACATTTTAAGCGATTTGGATAATGAAATCATTAGCCT
TAAAAACAAAAAACGCCAATTTGAAAGCATCAAAAAAGCTTTAAACCACGATTTAATGAGCGCTAAAATCAGGGTTTTAG
AAAATTAA

Upstream 100 bases:

>100_bases
AAATCTTGCTATTAAGGCTGGATTTTAACCCTAAAAACGCTTTTGATAACACCCTAAAATTAGAGCGCGCTATCTTTTTT
AAAACCATTCAAAAGAACGC

Downstream 100 bases:

>100_bases
AAATTGTATTAAGAGAGGTTCTTTATGCAATCCATGCAAAGCGTAATAGATTGTGAGAGCACCCAAGTTGTTAAAATTGT
TGTAAAATTCGTTTTTATTG

Product: type I R-M system specificity subunit

Products: NA

Alternate protein names: S protein [H]

Number of amino acids: Translated: 375; Mature: 375

Protein sequence:

>375_residues
MDALMLPLNWQRVRLGDIGKPCMCKRVMKHQTTRYGEIPFYKIGTFGNTADAFISKKLFLEYKTKYSFPKKGDILISASG
TIGKAVIYDGKPAYFQDSNIVWIDNDETLVKNDFLFYAYSNVKWNTEHTTILRLYNDNFRNTLIPLPPLNEQIAIANILS
DLDHYLYSLDALILKKESVKKALSFELLSQRKRLKGFNQAWQRVRLGDICEITTGSLDANEMVHYGKYRFYTCAKEYYFI
DKYAFDTEAILISGNGAYVGYVHYYKGKFNAYQRTYVLDNFSEHIIFIKYFLTMFLQSHIQTNRNEGNTPYIVTATLKDF
EILLPPLNEQIAIANILSDLDNEIISLKNKKRQFESIKKALNHDLMSAKIRVLEN

Sequences:

>Translated_375_residues
MDALMLPLNWQRVRLGDIGKPCMCKRVMKHQTTRYGEIPFYKIGTFGNTADAFISKKLFLEYKTKYSFPKKGDILISASG
TIGKAVIYDGKPAYFQDSNIVWIDNDETLVKNDFLFYAYSNVKWNTEHTTILRLYNDNFRNTLIPLPPLNEQIAIANILS
DLDHYLYSLDALILKKESVKKALSFELLSQRKRLKGFNQAWQRVRLGDICEITTGSLDANEMVHYGKYRFYTCAKEYYFI
DKYAFDTEAILISGNGAYVGYVHYYKGKFNAYQRTYVLDNFSEHIIFIKYFLTMFLQSHIQTNRNEGNTPYIVTATLKDF
EILLPPLNEQIAIANILSDLDNEIISLKNKKRQFESIKKALNHDLMSAKIRVLEN
>Mature_375_residues
MDALMLPLNWQRVRLGDIGKPCMCKRVMKHQTTRYGEIPFYKIGTFGNTADAFISKKLFLEYKTKYSFPKKGDILISASG
TIGKAVIYDGKPAYFQDSNIVWIDNDETLVKNDFLFYAYSNVKWNTEHTTILRLYNDNFRNTLIPLPPLNEQIAIANILS
DLDHYLYSLDALILKKESVKKALSFELLSQRKRLKGFNQAWQRVRLGDICEITTGSLDANEMVHYGKYRFYTCAKEYYFI
DKYAFDTEAILISGNGAYVGYVHYYKGKFNAYQRTYVLDNFSEHIIFIKYFLTMFLQSHIQTNRNEGNTPYIVTATLKDF
EILLPPLNEQIAIANILSDLDNEIISLKNKKRQFESIKKALNHDLMSAKIRVLEN

Specific function: The M and S subunits together form a methyltransferase (MTase) that methylates two adenine residues in complementary strands of a bipartite DNA recognition sequence. Subunit S dictates DNA sequences specificity [H]

COG id: COG0732

COG function: function code V; Restriction endonuclease S subunits

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the type-I restriction system S methylase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000055 [H]

Pfam domain/function: PF01420 Methylase_S [H]

EC number: NA

Molecular weight: Translated: 43564; Mature: 43564

Theoretical pI: Translated: 9.23; Mature: 9.23

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDALMLPLNWQRVRLGDIGKPCMCKRVMKHQTTRYGEIPFYKIGTFGNTADAFISKKLFL
CCEEEECCCCCEEEECCCCCHHHHHHHHHHCCCCCCCCCEEEECCCCCCHHHHHHHHHEE
EYKTKYSFPKKGDILISASGTIGKAVIYDGKPAYFQDSNIVWIDNDETLVKNDFLFYAYS
EEECCCCCCCCCCEEEEECCCCCEEEEECCCCCEEECCEEEEECCCCEEEECCEEEEEEE
NVKWNTEHTTILRLYNDNFRNTLIPLPPLNEQIAIANILSDLDHYLYSLDALILKKESVK
CEEECCCCEEEEEEECCCCCCCEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KALSFELLSQRKRLKGFNQAWQRVRLGDICEITTGSLDANEMVHYGKYRFYTCAKEYYFI
HHHHHHHHHHHHHHCHHHHHHHHCCCCCEEEEECCCCCHHHHHHCCCEEEEEEEEEEEEE
DKYAFDTEAILISGNGAYVGYVHYYKGKFNAYQRTYVLDNFSEHIIFIKYFLTMFLQSHI
EEEECCCEEEEEECCCEEEEEEEEECCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHH
QTNRNEGNTPYIVTATLKDFEILLPPLNEQIAIANILSDLDNEIISLKNKKRQFESIKKA
HCCCCCCCCCEEEEEEECCCEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LNHDLMSAKIRVLEN
HCCHHHHEEEEEECC
>Mature Secondary Structure
MDALMLPLNWQRVRLGDIGKPCMCKRVMKHQTTRYGEIPFYKIGTFGNTADAFISKKLFL
CCEEEECCCCCEEEECCCCCHHHHHHHHHHCCCCCCCCCEEEECCCCCCHHHHHHHHHEE
EYKTKYSFPKKGDILISASGTIGKAVIYDGKPAYFQDSNIVWIDNDETLVKNDFLFYAYS
EEECCCCCCCCCCEEEEECCCCCEEEEECCCCCEEECCEEEEECCCCEEEECCEEEEEEE
NVKWNTEHTTILRLYNDNFRNTLIPLPPLNEQIAIANILSDLDHYLYSLDALILKKESVK
CEEECCCCEEEEEEECCCCCCCEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KALSFELLSQRKRLKGFNQAWQRVRLGDICEITTGSLDANEMVHYGKYRFYTCAKEYYFI
HHHHHHHHHHHHHHCHHHHHHHHCCCCCEEEEECCCCCHHHHHHCCCEEEEEEEEEEEEE
DKYAFDTEAILISGNGAYVGYVHYYKGKFNAYQRTYVLDNFSEHIIFIKYFLTMFLQSHI
EEEECCCEEEEEECCCEEEEEEEEECCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHH
QTNRNEGNTPYIVTATLKDFEILLPPLNEQIAIANILSDLDNEIISLKNKKRQFESIKKA
HCCCCCCCCCEEEEEEECCCEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LNHDLMSAKIRVLEN
HCCHHHHEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]