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The map label for this gene is recG [H]

Identifier: 108563817

GI number: 108563817

Start: 1440714

End: 1442585

Strand: Direct

Name: recG [H]

Synonym: HPAG1_1392

Alternate gene names: 108563817

Gene position: 1440714-1442585 (Clockwise)

Preceding gene: 108563814

Following gene: 108563818

Centisome position: 90.25

GC content: 38.25

Gene sequence:

>1872_bases
TTGCAAGAAACAGATAATTTATTAAAAACATTGAATGTGAAATCGCTCTTAGAAGCCTTGCTTGTTTATACGCCCAAAGG
CTATAAAGATTTGAATTTATTAAAACATTTTGAACTGGGCTTGAGCGGCGTTTTAGAAGTGGGTATTTTAGAGAAAAGAA
ACTACGCCAAAGTTTTAAAGATTTTTGCCTATTCCAAACGATTTTACAAAAATTTAGAGCTTGTTTTTTTCAATTACAGC
GCGTTCCATCACAGCCAGTTTAAAACCGGCGAGAGTTTGTTCATTTATGGTAAATTAGAGCAAAGTTCTTTTAATCAAGC
TTATATCATTAACACGCCTAAAATCCTTACCGAATTTGGTAAAGTTTATTTAATTTTTAAAAAAGTTAAAAACCATAAAA
AAATACAAGAAAACTTACAAAAACTCCTTTCGTTAGAAAATTTAAAAAAGGAAGGCGTTAAAGAAAATATCGCGCGTTTA
TTGTTAGAAATCTTTTTCCCCACGCCGCATTTTGTCAAGGATTTTGAAACGAATAAAAATTTCCCTTCACAACATTTAAA
TGCATTAAAATACATTGAAATGCTTTTTTATATGAAAAATTTAGAGCGCAAAAAATTGCAATTTGGCGCTAAAATCGCAT
GCCCCAATAACAGCGAACGCTTGAAAGCGTTTATCGCTTCTTTACCTTTTAAACTCACGCGCGATCAACAAAACGCCATT
AAAGAAATCCAAAGCGATCTCACTAGCTCCATAGCGTGCAAGCGTTTGATTATAGGCGATGTGGGGTGCGGGAAAACAAT
GGTGATTTTAGCGAGCATGGTATTAGCTTACCCTAATAAAACCCTTTTAATGGCGCCCACTTCCATTCTCGCTAAACAGC
TTTATAACGAAGCCTTAAAATTTTTACCCCCTTATTTTGAAGTGGAATTGCTGCTTGGCGGGAGCCGCAAGAAGCGATCC
AATCATTTGTTTGAAACAATCACGCATGTTATTATAGGCACGCAAGCGTTGTTGTTTGATCAGCGCGATTTGAATGAATT
CGCATTAGTGATCACTGATGAGCAGCACCGATTTGGCACCAAGCAGCGCTACCAATTAGAAAAAATGGCAAGCAGTAAGG
GTAATAAACCCCATTCTTTGCAATTTTCCGCTACCCCCATTCCTCGCACGCTCGCCCTAGCCAAAAGCGCGTTTGTGAAA
ACGACCATGATTAGAGAAATCCCTTACCCTAAAGAGATTGAAACTTTAGTCTTGCATAAAAGAGATTTTAAAATAGTGAT
GGAAAAAATCAACGAAGAAATCGCTAAAAACCATCAAGTCATTGTCGTTTATCCGCTGGTGAATGAAAGCGAAAAAATCC
CGTATTTATCGCTCAGTGAGGGGGCGAGTTTTTGGCAAAAACGCTTTAAAAACGTTTATACCACTTCAGGGCAGGATAAA
AATAAAGAAGAAGTGATTGAAGAATTTAGAGAGTCCGGGAGTATTCTTTTAGCGACTACGCTCATTGAGGTGGGCATTTC
TTTACCACGATTGAGCGTGATGGTGATTTTAGCGCCCGAAAGGTTAGGCTTAGCGACTTTACACCAGTTAAGGGGGCGCG
TGTCTCGTAACGGCTTGAAAGGCTATTGTTTTTTATGCACGATCCAAGAAGAAAACGAACGATTAGAAAAGTTTGCTGAT
GAATTGGACGGCTTTAAAATCGCTGAATTGGATTTACAATACAGAAAAAGCGGGGATTTACTCCAGGGCGGGGAGCAGAG
CGGGAATAGTTTTGAATACATTGACTTAGCCAAAGATGAAATCCTTATCGCTGAAGTGAAACAGGATTTTTTAAAGGCCG
CTAGCGTTTCACGGGGAACATTTGAAAATTGA

Upstream 100 bases:

>100_bases
GAGTGATTTTAGATTTCATCAATTAAATTTCCTTAAGTCAATGTATAATTTGACTATCTTATCATAAAAATGATTAAGGA
TTGGCTAGGGTAAGAACAAA

Downstream 100 bases:

>100_bases
AAATTGAAAATTAAGGCAGAATTGGGTAATTTAAATCATTTAAAAAAGGATAGAGATGCAAAATAAAGAAATTGGTGGAG
AAAAAAGCGTTAATGAAAAA

Product: ATP-dependent DNA helicase RecG

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 623; Mature: 623

Protein sequence:

>623_residues
MQETDNLLKTLNVKSLLEALLVYTPKGYKDLNLLKHFELGLSGVLEVGILEKRNYAKVLKIFAYSKRFYKNLELVFFNYS
AFHHSQFKTGESLFIYGKLEQSSFNQAYIINTPKILTEFGKVYLIFKKVKNHKKIQENLQKLLSLENLKKEGVKENIARL
LLEIFFPTPHFVKDFETNKNFPSQHLNALKYIEMLFYMKNLERKKLQFGAKIACPNNSERLKAFIASLPFKLTRDQQNAI
KEIQSDLTSSIACKRLIIGDVGCGKTMVILASMVLAYPNKTLLMAPTSILAKQLYNEALKFLPPYFEVELLLGGSRKKRS
NHLFETITHVIIGTQALLFDQRDLNEFALVITDEQHRFGTKQRYQLEKMASSKGNKPHSLQFSATPIPRTLALAKSAFVK
TTMIREIPYPKEIETLVLHKRDFKIVMEKINEEIAKNHQVIVVYPLVNESEKIPYLSLSEGASFWQKRFKNVYTTSGQDK
NKEEVIEEFRESGSILLATTLIEVGISLPRLSVMVILAPERLGLATLHQLRGRVSRNGLKGYCFLCTIQEENERLEKFAD
ELDGFKIAELDLQYRKSGDLLQGGEQSGNSFEYIDLAKDEILIAEVKQDFLKAASVSRGTFEN

Sequences:

>Translated_623_residues
MQETDNLLKTLNVKSLLEALLVYTPKGYKDLNLLKHFELGLSGVLEVGILEKRNYAKVLKIFAYSKRFYKNLELVFFNYS
AFHHSQFKTGESLFIYGKLEQSSFNQAYIINTPKILTEFGKVYLIFKKVKNHKKIQENLQKLLSLENLKKEGVKENIARL
LLEIFFPTPHFVKDFETNKNFPSQHLNALKYIEMLFYMKNLERKKLQFGAKIACPNNSERLKAFIASLPFKLTRDQQNAI
KEIQSDLTSSIACKRLIIGDVGCGKTMVILASMVLAYPNKTLLMAPTSILAKQLYNEALKFLPPYFEVELLLGGSRKKRS
NHLFETITHVIIGTQALLFDQRDLNEFALVITDEQHRFGTKQRYQLEKMASSKGNKPHSLQFSATPIPRTLALAKSAFVK
TTMIREIPYPKEIETLVLHKRDFKIVMEKINEEIAKNHQVIVVYPLVNESEKIPYLSLSEGASFWQKRFKNVYTTSGQDK
NKEEVIEEFRESGSILLATTLIEVGISLPRLSVMVILAPERLGLATLHQLRGRVSRNGLKGYCFLCTIQEENERLEKFAD
ELDGFKIAELDLQYRKSGDLLQGGEQSGNSFEYIDLAKDEILIAEVKQDFLKAASVSRGTFEN
>Mature_623_residues
MQETDNLLKTLNVKSLLEALLVYTPKGYKDLNLLKHFELGLSGVLEVGILEKRNYAKVLKIFAYSKRFYKNLELVFFNYS
AFHHSQFKTGESLFIYGKLEQSSFNQAYIINTPKILTEFGKVYLIFKKVKNHKKIQENLQKLLSLENLKKEGVKENIARL
LLEIFFPTPHFVKDFETNKNFPSQHLNALKYIEMLFYMKNLERKKLQFGAKIACPNNSERLKAFIASLPFKLTRDQQNAI
KEIQSDLTSSIACKRLIIGDVGCGKTMVILASMVLAYPNKTLLMAPTSILAKQLYNEALKFLPPYFEVELLLGGSRKKRS
NHLFETITHVIIGTQALLFDQRDLNEFALVITDEQHRFGTKQRYQLEKMASSKGNKPHSLQFSATPIPRTLALAKSAFVK
TTMIREIPYPKEIETLVLHKRDFKIVMEKINEEIAKNHQVIVVYPLVNESEKIPYLSLSEGASFWQKRFKNVYTTSGQDK
NKEEVIEEFRESGSILLATTLIEVGISLPRLSVMVILAPERLGLATLHQLRGRVSRNGLKGYCFLCTIQEENERLEKFAD
ELDGFKIAELDLQYRKSGDLLQGGEQSGNSFEYIDLAKDEILIAEVKQDFLKAASVSRGTFEN

Specific function: Critical role in recombination and DNA repair. Help process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3' to 5' polarity. RecG unwind branched dup

COG id: COG1200

COG function: function code LK; RecG-like helicase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 helicase C-terminal domain [H]

Homologues:

Organism=Escherichia coli, GI2367254, Length=578, Percent_Identity=31.8339100346021, Blast_Score=232, Evalue=5e-62,
Organism=Escherichia coli, GI1787357, Length=393, Percent_Identity=31.8066157760814, Blast_Score=166, Evalue=4e-42,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014001
- InterPro:   IPR011545
- InterPro:   IPR004609
- InterPro:   IPR001650
- InterPro:   IPR014021 [H]

Pfam domain/function: PF00270 DEAD; PF00271 Helicase_C [H]

EC number: =3.6.4.12 [H]

Molecular weight: Translated: 71374; Mature: 71374

Theoretical pI: Translated: 9.72; Mature: 9.72

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQETDNLLKTLNVKSLLEALLVYTPKGYKDLNLLKHFELGLSGVLEVGILEKRNYAKVLK
CCCHHHHHHHCCHHHHHHHHHHCCCCCCCHHHHHHHHHHCHHHHHHHHHHCCCCHHHHHH
IFAYSKRFYKNLELVFFNYSAFHHSQFKTGESLFIYGKLEQSSFNQAYIINTPKILTEFG
HHHHHHHHHCCEEEEEEECCHHCCCCCCCCCEEEEEEEECCCCCCCEEEEECHHHHHHHH
KVYLIFKKVKNHKKIQENLQKLLSLENLKKEGVKENIARLLLEIFFPTPHFVKDFETNKN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCHHHHHCCCCCC
FPSQHLNALKYIEMLFYMKNLERKKLQFGAKIACPNNSERLKAFIASLPFKLTRDQQNAI
CCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCHHHHHHHHHHCCCCCCCCHHHHH
KEIQSDLTSSIACKRLIIGDVGCGKTMVILASMVLAYPNKTLLMAPTSILAKQLYNEALK
HHHHHHHHHHHHHHHHHEECCCCCHHHHHHHHHHHHCCCCEEEECCHHHHHHHHHHHHHH
FLPPYFEVELLLGGSRKKRSNHLFETITHVIIGTQALLFDQRDLNEFALVITDEQHRFGT
HCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHCCHHEEECCCCCCCEEEEEECCHHHCCC
KQRYQLEKMASSKGNKPHSLQFSATPIPRTLALAKSAFVKTTMIREIPYPKEIETLVLHK
HHHHHHHHHHHCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
RDFKIVMEKINEEIAKNHQVIVVYPLVNESEKIPYLSLSEGASFWQKRFKNVYTTSGQDK
HHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCEEECCCCHHHHHHHHHHHCCCCCCCC
NKEEVIEEFRESGSILLATTLIEVGISLPRLSVMVILAPERLGLATLHQLRGRVSRNGLK
CHHHHHHHHHHCCCEEEEHHHHHHCCCCCCEEEEEEECCCCCCHHHHHHHHHHHHCCCCC
GYCFLCTIQEENERLEKFADELDGFKIAELDLQYRKSGDLLQGGEQSGNSFEYIDLAKDE
EEEEEEEEECHHHHHHHHHHHHCCCEEEEEEHHHCCCCCCCCCCCCCCCCEEEEECCCCH
ILIAEVKQDFLKAASVSRGTFEN
HHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MQETDNLLKTLNVKSLLEALLVYTPKGYKDLNLLKHFELGLSGVLEVGILEKRNYAKVLK
CCCHHHHHHHCCHHHHHHHHHHCCCCCCCHHHHHHHHHHCHHHHHHHHHHCCCCHHHHHH
IFAYSKRFYKNLELVFFNYSAFHHSQFKTGESLFIYGKLEQSSFNQAYIINTPKILTEFG
HHHHHHHHHCCEEEEEEECCHHCCCCCCCCCEEEEEEEECCCCCCCEEEEECHHHHHHHH
KVYLIFKKVKNHKKIQENLQKLLSLENLKKEGVKENIARLLLEIFFPTPHFVKDFETNKN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCHHHHHCCCCCC
FPSQHLNALKYIEMLFYMKNLERKKLQFGAKIACPNNSERLKAFIASLPFKLTRDQQNAI
CCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCHHHHHHHHHHCCCCCCCCHHHHH
KEIQSDLTSSIACKRLIIGDVGCGKTMVILASMVLAYPNKTLLMAPTSILAKQLYNEALK
HHHHHHHHHHHHHHHHHEECCCCCHHHHHHHHHHHHCCCCEEEECCHHHHHHHHHHHHHH
FLPPYFEVELLLGGSRKKRSNHLFETITHVIIGTQALLFDQRDLNEFALVITDEQHRFGT
HCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHCCHHEEECCCCCCCEEEEEECCHHHCCC
KQRYQLEKMASSKGNKPHSLQFSATPIPRTLALAKSAFVKTTMIREIPYPKEIETLVLHK
HHHHHHHHHHHCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
RDFKIVMEKINEEIAKNHQVIVVYPLVNESEKIPYLSLSEGASFWQKRFKNVYTTSGQDK
HHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCEEECCCCHHHHHHHHHHHCCCCCCCC
NKEEVIEEFRESGSILLATTLIEVGISLPRLSVMVILAPERLGLATLHQLRGRVSRNGLK
CHHHHHHHHHHCCCEEEEHHHHHHCCCCCCEEEEEEECCCCCCHHHHHHHHHHHHCCCCC
GYCFLCTIQEENERLEKFADELDGFKIAELDLQYRKSGDLLQGGEQSGNSFEYIDLAKDE
EEEEEEEEECHHHHHHHHHHHHCCCEEEEEEHHHCCCCCCCCCCCCCCCCEEEEECCCCH
ILIAEVKQDFLKAASVSRGTFEN
HHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9923682 [H]