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The map label for this gene is cptA [H]

Identifier: 108563768

GI number: 108563768

Start: 1393668

End: 1395293

Strand: Direct

Name: cptA [H]

Synonym: HPAG1_1343

Alternate gene names: 108563768

Gene position: 1393668-1395293 (Clockwise)

Preceding gene: 108563767

Following gene: 108563775

Centisome position: 87.3

GC content: 36.53

Gene sequence:

>1626_bases
ATGGAAAAATTATTGAAGTTTTTAATATTCCTTCTTTGCAACGCTCTTTCTAACGCCTACAAAAATAGCGATTTGTTTTC
TTTCTCTAAAGGCTTTTTAGGCGCTTTTTTAATCGGGTTTGTGGTGTATTATGGCTGCGCGCTAATCCCTAAAAAGCGTT
TGAAATATTCATTAGAATGGCTGTTTATAGGAAGCGGTATTATCTTTAGCGTGGCAGAAATTTTTACGCTCTTTATGTTT
AAAATGCCTTTTTCCAAAGGCTTGATTGACACGCTTTTAGCCACAAACAGCTCTGAAACGATGGCGTTTATAAAAAGCTA
TAAAAATTATTTGTTTTACTATGTTTTTATTTTGATCGCTTTATTGATTGTTATTAAAATCATTCGCTTTAGAGTGCTTG
TGCCTGGTGTGATAGCGGGCGTTTTAGGGCTTTCTATCCTTACAATAGGGAGCGTTCGTAACATTAAACACCTTACAGAG
AACGACGCCATTTTAAAAAGATCATTGTTTTCTCTTTCCTTAACTAGGGGGTTTTATTCCGCCTATTTGAGCTTGTTTGA
TCGCCAACAAGCCATAAAATTTTATAGCTTTTTAAATAACCTTTATTTACCAAGCGATTATCTTTCTAGCACGGGCGATG
TTGAAAATGTCGTCTTAGTCATCGGTGAAAGCGCGAGCAGAAATTTCATGCAACTCTATGGCTATAACGCCCCTAATAAC
CCCTTATTGAGCAAACTCGCCAACGAGAGAGAGAGAGAGAGTAACAACCTGTTCGTGTTTTCTGACACGATAAGCAAAGA
AGCCCACACCTCTGATGTCTTTGAAAACTTGCTCAATTACAGCAACGCCGAAACGAATAAGCCTTGGTATCATTATCACA
ACATGATAGATATTTTCAAGCGATCCCATTATGAAACTTTTTGGTTAGAAAAACAAATCGTCGATCAATGGGGGATCACA
CAAAATCTAGTCTCTAATCGTTCTAAAAACCGCTACTATATTTTGGGAAACTATGGTGCATACGATGAAGAGCTGGCGAA
ATTTTATACCAAAAATGTCCAACCAAAATTAAAGGAAAAGAATTTTATCGTGTTCCATTTGATTGGCTCTCATTCTTGGT
ACGCCGATCGTTTCCCTAAAAGCTTTGCCAAATTCAAACCAAGCGATTTGTCTTTTTCCAATCTGCATGCAAGCAGCGAT
AGAGACAAACAAATCGTTGCCGATTATGTCAATTCACTTTATTATAACGACTTTGTTTTGAATGGGATTTTTAACCTCTT
TAAAGATAAGGACGCTATCGTGTTTTACTTGAGCGACCATGCGCAAGATATTTTTGAAAGCAACCCTACTTATGGGCACA
GATGCTCTAAAGCGGGATTAGAAATCCCTTTTATGATTTATGTGAGCGATATTTTTAAAGAAAAACACCCAGAGAAAGTA
AAGTTGATTAAAAACGCTTTAAACAAACCTTTCATGAGCGATGATTTAATCCATTCTCTTTTGCCTTTGGTAGGCATTCA
CACTAAAGATGAAATAGAGAGTAAAAATCTTTTTAGCCCTAAATTTGACACTCAAAGAAAAAGGGCTGTTTGTTATGGCA
GCATGAATTATGATAGGACTAAATAG

Upstream 100 bases:

>100_bases
TTTTAAAACCCACATAAGATCGCAAACGATTAGGGATTATTTTTATTTTAGGATAAAAAATATTTTGAAAAAAGTTTTCA
AACTTTCTTAAAGGGCATTC

Downstream 100 bases:

>100_bases
TAATAAGGCTCTACTCTCATCAATTAGGGTAAGATTGATTTTAATAAAGCCTTTCAACCCTACCTTAAAATCTTCACTTC
TTCTTCTAAATGAATGCCGT

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 541; Mature: 541

Protein sequence:

>541_residues
MEKLLKFLIFLLCNALSNAYKNSDLFSFSKGFLGAFLIGFVVYYGCALIPKKRLKYSLEWLFIGSGIIFSVAEIFTLFMF
KMPFSKGLIDTLLATNSSETMAFIKSYKNYLFYYVFILIALLIVIKIIRFRVLVPGVIAGVLGLSILTIGSVRNIKHLTE
NDAILKRSLFSLSLTRGFYSAYLSLFDRQQAIKFYSFLNNLYLPSDYLSSTGDVENVVLVIGESASRNFMQLYGYNAPNN
PLLSKLANERERESNNLFVFSDTISKEAHTSDVFENLLNYSNAETNKPWYHYHNMIDIFKRSHYETFWLEKQIVDQWGIT
QNLVSNRSKNRYYILGNYGAYDEELAKFYTKNVQPKLKEKNFIVFHLIGSHSWYADRFPKSFAKFKPSDLSFSNLHASSD
RDKQIVADYVNSLYYNDFVLNGIFNLFKDKDAIVFYLSDHAQDIFESNPTYGHRCSKAGLEIPFMIYVSDIFKEKHPEKV
KLIKNALNKPFMSDDLIHSLLPLVGIHTKDEIESKNLFSPKFDTQRKRAVCYGSMNYDRTK

Sequences:

>Translated_541_residues
MEKLLKFLIFLLCNALSNAYKNSDLFSFSKGFLGAFLIGFVVYYGCALIPKKRLKYSLEWLFIGSGIIFSVAEIFTLFMF
KMPFSKGLIDTLLATNSSETMAFIKSYKNYLFYYVFILIALLIVIKIIRFRVLVPGVIAGVLGLSILTIGSVRNIKHLTE
NDAILKRSLFSLSLTRGFYSAYLSLFDRQQAIKFYSFLNNLYLPSDYLSSTGDVENVVLVIGESASRNFMQLYGYNAPNN
PLLSKLANERERESNNLFVFSDTISKEAHTSDVFENLLNYSNAETNKPWYHYHNMIDIFKRSHYETFWLEKQIVDQWGIT
QNLVSNRSKNRYYILGNYGAYDEELAKFYTKNVQPKLKEKNFIVFHLIGSHSWYADRFPKSFAKFKPSDLSFSNLHASSD
RDKQIVADYVNSLYYNDFVLNGIFNLFKDKDAIVFYLSDHAQDIFESNPTYGHRCSKAGLEIPFMIYVSDIFKEKHPEKV
KLIKNALNKPFMSDDLIHSLLPLVGIHTKDEIESKNLFSPKFDTQRKRAVCYGSMNYDRTK
>Mature_541_residues
MEKLLKFLIFLLCNALSNAYKNSDLFSFSKGFLGAFLIGFVVYYGCALIPKKRLKYSLEWLFIGSGIIFSVAEIFTLFMF
KMPFSKGLIDTLLATNSSETMAFIKSYKNYLFYYVFILIALLIVIKIIRFRVLVPGVIAGVLGLSILTIGSVRNIKHLTE
NDAILKRSLFSLSLTRGFYSAYLSLFDRQQAIKFYSFLNNLYLPSDYLSSTGDVENVVLVIGESASRNFMQLYGYNAPNN
PLLSKLANERERESNNLFVFSDTISKEAHTSDVFENLLNYSNAETNKPWYHYHNMIDIFKRSHYETFWLEKQIVDQWGIT
QNLVSNRSKNRYYILGNYGAYDEELAKFYTKNVQPKLKEKNFIVFHLIGSHSWYADRFPKSFAKFKPSDLSFSNLHASSD
RDKQIVADYVNSLYYNDFVLNGIFNLFKDKDAIVFYLSDHAQDIFESNPTYGHRCSKAGLEIPFMIYVSDIFKEKHPEKV
KLIKNALNKPFMSDDLIHSLLPLVGIHTKDEIESKNLFSPKFDTQRKRAVCYGSMNYDRTK

Specific function: Catalyzes the addition of a phosphoethanolamine moiety to the outer membrane lipopolysaccharide core [H]

COG id: COG2194

COG function: function code R; Predicted membrane-associated, metal-dependent hydrolase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the phosphoethanolamine transferase family. CptA subfamily [H]

Homologues:

Organism=Escherichia coli, GI87082223, Length=462, Percent_Identity=24.025974025974, Blast_Score=119, Evalue=3e-28,
Organism=Escherichia coli, GI1790392, Length=567, Percent_Identity=23.4567901234568, Blast_Score=113, Evalue=3e-26,
Organism=Escherichia coli, GI87082286, Length=374, Percent_Identity=24.331550802139, Blast_Score=79, Evalue=6e-16,
Organism=Escherichia coli, GI87082372, Length=311, Percent_Identity=25.08038585209, Blast_Score=79, Evalue=1e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017849
- InterPro:   IPR017850
- InterPro:   IPR000917 [H]

Pfam domain/function: PF00884 Sulfatase [H]

EC number: NA

Molecular weight: Translated: 62596; Mature: 62596

Theoretical pI: Translated: 9.43; Mature: 9.43

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEKLLKFLIFLLCNALSNAYKNSDLFSFSKGFLGAFLIGFVVYYGCALIPKKRLKYSLEW
CHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHEEEE
LFIGSGIIFSVAEIFTLFMFKMPFSKGLIDTLLATNSSETMAFIKSYKNYLFYYVFILIA
EEECCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHH
LLIVIKIIRFRVLVPGVIAGVLGLSILTIGSVRNIKHLTENDAILKRSLFSLSLTRGFYS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHH
AYLSLFDRQQAIKFYSFLNNLYLPSDYLSSTGDVENVVLVIGESASRNFMQLYGYNAPNN
HHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCCCCCEEEEEEECCCCCCHHHHCCCCCCCC
PLLSKLANERERESNNLFVFSDTISKEAHTSDVFENLLNYSNAETNKPWYHYHNMIDIFK
HHHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHH
RSHYETFWLEKQIVDQWGITQNLVSNRSKNRYYILGNYGAYDEELAKFYTKNVQPKLKEK
HCCCHHHHHHHHHHHHHCCHHHHHCCCCCCEEEEEECCCCCHHHHHHHHHCCCCCCCCCC
NFIVFHLIGSHSWYADRFPKSFAKFKPSDLSFSNLHASSDRDKQIVADYVNSLYYNDFVL
CEEEEEEECCCCCHHHHHHHHHHCCCCCCCCHHHCCCCCCCHHHHHHHHHHHHHHHHHHH
NGIFNLFKDKDAIVFYLSDHAQDIFESNPTYGHRCSKAGLEIPFMIYVSDIFKEKHPEKV
HHHHHHHCCCCEEEEEECHHHHHHHHCCCCCCCHHHHCCCCCCHHHHHHHHHHHCCCHHH
KLIKNALNKPFMSDDLIHSLLPLVGIHTKDEIESKNLFSPKFDTQRKRAVCYGSMNYDRT
HHHHHHHCCCCCCHHHHHHHHHHHCCCCHHHHCCCCCCCCCCCCCCCCEEEEECCCCCCC
K
C
>Mature Secondary Structure
MEKLLKFLIFLLCNALSNAYKNSDLFSFSKGFLGAFLIGFVVYYGCALIPKKRLKYSLEW
CHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHEEEE
LFIGSGIIFSVAEIFTLFMFKMPFSKGLIDTLLATNSSETMAFIKSYKNYLFYYVFILIA
EEECCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHH
LLIVIKIIRFRVLVPGVIAGVLGLSILTIGSVRNIKHLTENDAILKRSLFSLSLTRGFYS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHH
AYLSLFDRQQAIKFYSFLNNLYLPSDYLSSTGDVENVVLVIGESASRNFMQLYGYNAPNN
HHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCCCCCEEEEEEECCCCCCHHHHCCCCCCCC
PLLSKLANERERESNNLFVFSDTISKEAHTSDVFENLLNYSNAETNKPWYHYHNMIDIFK
HHHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHH
RSHYETFWLEKQIVDQWGITQNLVSNRSKNRYYILGNYGAYDEELAKFYTKNVQPKLKEK
HCCCHHHHHHHHHHHHHCCHHHHHCCCCCCEEEEEECCCCCHHHHHHHHHCCCCCCCCCC
NFIVFHLIGSHSWYADRFPKSFAKFKPSDLSFSNLHASSDRDKQIVADYVNSLYYNDFVL
CEEEEEEECCCCCHHHHHHHHHHCCCCCCCCHHHCCCCCCCHHHHHHHHHHHHHHHHHHH
NGIFNLFKDKDAIVFYLSDHAQDIFESNPTYGHRCSKAGLEIPFMIYVSDIFKEKHPEKV
HHHHHHHCCCCEEEEEECHHHHHHHHCCCCCCCHHHHCCCCCCHHHHHHHHHHHCCCHHH
KLIKNALNKPFMSDDLIHSLLPLVGIHTKDEIESKNLFSPKFDTQRKRAVCYGSMNYDRT
HHHHHHHCCCCCCHHHHHHHHHHHCCCCHHHHCCCCCCCCCCCCCCCCEEEEECCCCCCC
K
C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11677609 [H]