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The map label for this gene is nuoG2 [H]

Identifier: 108563635

GI number: 108563635

Start: 1270517

End: 1273051

Strand: Direct

Name: nuoG2 [H]

Synonym: HPAG1_1210

Alternate gene names: 108563635

Gene position: 1270517-1273051 (Clockwise)

Preceding gene: 108563634

Following gene: 108563636

Centisome position: 79.59

GC content: 41.62

Gene sequence:

>2535_bases
ATGATCACAATGAATATCAATGGCAAAACGATTGAATGCCAAGAGGGACAAAGCGTTTTAGAGGCCGCTAGGAGCGCTGG
GATCTACATCCCTACCATTTGCTATTTAAGCGGTTGCTCGCCCACAGTCGCATGCAAAATGTGCATGGTTGAAATGGATG
GCAAACGGGTTTATAGCTGCAACACGAAAGCCAAAAATAACGCCACCATTCTCACTAACACCCCAACGCTCATGGATGAA
AGAAAAAGCATCATGCAAACTTATGATGTCAACCACCCCCTAGAGTGTGGCGTGTGCGATAAGAGCGGGGAGTGCGAATT
GCAAGACATGACGCATTTAACTGGCGTAGAGCACCAACCTTATGCGGTGGCTGATGATTTTAAAGCGCTAGATTCATGGG
CAAAAGCCTTGTATGATCCTAATTTGTGCATCATGTGCGAAAGGTGCGTAACCACTTGCAAGGACAATGTGGGCGAAAAC
AACCTTAAAGCCACTAAAGCCGACTTGCATGCTCCGGATAAATTTAAAGACCGCATGTCCAAAGACGCTTTTAGCGTGTG
GAGTCGCAAGCAAAAAGGCATTATTTCTTTTGTGGGCAGCGTGCCTTGTTATGATTGCGGGGAATGCATTGCGGTATGCC
CTGTGGGCGCTTTGAGCTATAAAGATTTCGCTTACACGGCTAACGCATGGGAACTCAAAAAGATCCATTCTACTTGTTCG
CATTGCTCAGCTGGGTGTTTGATTTCTTATGATGTGCGCCATTTTGATACTCTAGGCGAAGAATCTAAGATTTTTAGGGT
GCTTAATGATTTTTACCATAACCCTATTTGTGGGGCAGGCCGTTTCGCTTTTGACGTGAGCTCTAGCCCTAAAGGCAGCA
CTAATCTTAAAGAAGCGCAAAACGCCCTCAAAGAATGCGAAGCGGTGCGAATAGGTGGGGATATTACGAATGAAGAGGCG
TTTTTAATAGAGCGTTTGAGGAAAGAGCTTGATTTTAAAATCTACAATCAAGAAGTGTATCATTTCCAGCAATTCTTAAA
AGTATTGGGCGAAGTTAAACGCCCCAATATTGAAGAGATTAAAACTTCCAATTTGGTCGTTACGATAGGATCTTCTATCA
AAACAGAAAACCCTTTGGTGCGCTATGCCATCAATAACGCTCTCAAACTCAATAAAGCTTCTTTGATCGCTATGCACCCT
ATTAAGGATAATGCGTTAGCGAATTTGTGTCGAAGCTCTTTTTGCATCACCCATGAAGTGGGGGCTGAAGAAATCCTTTT
AGGCATGCTTTTAAAAATGCTTAACATTGAAAGCGCAGCTCTAAAAAGCTTAGAAGATTCCAAGCAAAGCATTGTGGATG
AAGCGGCTCTTAAAGCCTTAGAAGAAGAGCGAAAAAAAGCTTTAGAACAAGCCGAGCAAGGGTGCAGTATTGGAGAAAAT
AAGGCAGAAAATCAAGAAGAGGATAAAATAGAAGCAACTACCCCAAAAGAAGAAAATCCAGAAGAAAACAAGACAGAGGT
TAAAGAAGAAAAAATTGAAGTCCCTACCAAAACCACTTATTTGTTGCTTGAAGAAGCGGGCATCAATTTAGAAACTTATG
AAAAAATTCTCGCTCTTTTGCAAAAATCAAATAACACCTTGCTGGTGGTTGGCGAAGAAATTTATAGCCACAAACAAGCC
CACAATATCGCTAAAATGTTGCGTTTGTTAGCCCAAAAAAGCGCTGTTAAACTCATTCTTATCCCTCCAAGCGCGAACGC
TTTAGGCATCGCTTCTATTTGTCAATTGAGCGAAGAAATTTTTGAACATGAAAAAATCGTAGGCATTCGCGCTCAAGGGG
ATTTCACTATCAATAGCGATGATAGGGTTTTTGGGAAAGACGCTCTCAGCAAAGTGGATTTTATTTTGCCCAGTCTCAAT
CAGCTAGAAGGCACGATCACCAATGTTGAAGGGCGTGTGTTGCCCTTAAAACCGGCTTTGAGGTTTGAGGGCTATGACTT
GAGCGATATTATGCAAGGCTTTGGCTTTGTGGAAGAAAATCTCACAGAATGCACCCACAAACTCCCTACAGAAGCGGGCT
TTAAAGCCATAGAATTTGATTATTTAACCAACTATTTCACTAACGACAGGGTCAATCACAGAGGCTATCTGCTAAGAGCA
AGCCCTTTTGAAAAAAGCGCTAAAGAATGCGAAACCATAGAATGCGAGCCTATCAAGCCTTTAAAAGAAAAAATCGCTTT
CAACGCGTATTTAAAATACCCAGAAACGCAATTCAATAACGCTACTAATAAAAGCGAGAATTTGCAATTAAAAGCCGGTG
TCTATGTGTCTAAAGCTTTCTTAAAAAAATTGAATAAAGAAGTGGGGCAAAACATCACTTTATCTAAAGAAGAAGAGGAA
TTAACAGGCGTTTTGTATCTTGATGAAAGCTTGGATCAGGAAGTGTTTGTCATCTCGCCTTCTCTTTTGAAAAACCATTC
TGGCTTTTTTAGAGAGAGCGTGTTTGATAGCGTGGATTTAAAGGAGCAAGCATGA

Upstream 100 bases:

>100_bases
AAGAAAGCCCTAATTTAAAGGGCTTGATCGCGATTTTAGAAGGGGCGTTTTTTGACGCTTACCCTTATATCCCTATTTTA
TCCCACTCTCAAGGAATTTC

Downstream 100 bases:

>100_bases
GCGCTTATATCATTGAAACCCTGATTAAAATTTTGATTTTAGTCGCTGTTTTTTCGGCTTTAGGAGGCTTTGCCACTTAT
ATTGAAAGGAAAGTGTTAGC

Product: NADH dehydrogenase subunit G

Products: NA

Alternate protein names: NADH dehydrogenase I subunit G 2; NDH-1 subunit G 2 [H]

Number of amino acids: Translated: 844; Mature: 844

Protein sequence:

>844_residues
MITMNINGKTIECQEGQSVLEAARSAGIYIPTICYLSGCSPTVACKMCMVEMDGKRVYSCNTKAKNNATILTNTPTLMDE
RKSIMQTYDVNHPLECGVCDKSGECELQDMTHLTGVEHQPYAVADDFKALDSWAKALYDPNLCIMCERCVTTCKDNVGEN
NLKATKADLHAPDKFKDRMSKDAFSVWSRKQKGIISFVGSVPCYDCGECIAVCPVGALSYKDFAYTANAWELKKIHSTCS
HCSAGCLISYDVRHFDTLGEESKIFRVLNDFYHNPICGAGRFAFDVSSSPKGSTNLKEAQNALKECEAVRIGGDITNEEA
FLIERLRKELDFKIYNQEVYHFQQFLKVLGEVKRPNIEEIKTSNLVVTIGSSIKTENPLVRYAINNALKLNKASLIAMHP
IKDNALANLCRSSFCITHEVGAEEILLGMLLKMLNIESAALKSLEDSKQSIVDEAALKALEEERKKALEQAEQGCSIGEN
KAENQEEDKIEATTPKEENPEENKTEVKEEKIEVPTKTTYLLLEEAGINLETYEKILALLQKSNNTLLVVGEEIYSHKQA
HNIAKMLRLLAQKSAVKLILIPPSANALGIASICQLSEEIFEHEKIVGIRAQGDFTINSDDRVFGKDALSKVDFILPSLN
QLEGTITNVEGRVLPLKPALRFEGYDLSDIMQGFGFVEENLTECTHKLPTEAGFKAIEFDYLTNYFTNDRVNHRGYLLRA
SPFEKSAKECETIECEPIKPLKEKIAFNAYLKYPETQFNNATNKSENLQLKAGVYVSKAFLKKLNKEVGQNITLSKEEEE
LTGVLYLDESLDQEVFVISPSLLKNHSGFFRESVFDSVDLKEQA

Sequences:

>Translated_844_residues
MITMNINGKTIECQEGQSVLEAARSAGIYIPTICYLSGCSPTVACKMCMVEMDGKRVYSCNTKAKNNATILTNTPTLMDE
RKSIMQTYDVNHPLECGVCDKSGECELQDMTHLTGVEHQPYAVADDFKALDSWAKALYDPNLCIMCERCVTTCKDNVGEN
NLKATKADLHAPDKFKDRMSKDAFSVWSRKQKGIISFVGSVPCYDCGECIAVCPVGALSYKDFAYTANAWELKKIHSTCS
HCSAGCLISYDVRHFDTLGEESKIFRVLNDFYHNPICGAGRFAFDVSSSPKGSTNLKEAQNALKECEAVRIGGDITNEEA
FLIERLRKELDFKIYNQEVYHFQQFLKVLGEVKRPNIEEIKTSNLVVTIGSSIKTENPLVRYAINNALKLNKASLIAMHP
IKDNALANLCRSSFCITHEVGAEEILLGMLLKMLNIESAALKSLEDSKQSIVDEAALKALEEERKKALEQAEQGCSIGEN
KAENQEEDKIEATTPKEENPEENKTEVKEEKIEVPTKTTYLLLEEAGINLETYEKILALLQKSNNTLLVVGEEIYSHKQA
HNIAKMLRLLAQKSAVKLILIPPSANALGIASICQLSEEIFEHEKIVGIRAQGDFTINSDDRVFGKDALSKVDFILPSLN
QLEGTITNVEGRVLPLKPALRFEGYDLSDIMQGFGFVEENLTECTHKLPTEAGFKAIEFDYLTNYFTNDRVNHRGYLLRA
SPFEKSAKECETIECEPIKPLKEKIAFNAYLKYPETQFNNATNKSENLQLKAGVYVSKAFLKKLNKEVGQNITLSKEEEE
LTGVLYLDESLDQEVFVISPSLLKNHSGFFRESVFDSVDLKEQA
>Mature_844_residues
MITMNINGKTIECQEGQSVLEAARSAGIYIPTICYLSGCSPTVACKMCMVEMDGKRVYSCNTKAKNNATILTNTPTLMDE
RKSIMQTYDVNHPLECGVCDKSGECELQDMTHLTGVEHQPYAVADDFKALDSWAKALYDPNLCIMCERCVTTCKDNVGEN
NLKATKADLHAPDKFKDRMSKDAFSVWSRKQKGIISFVGSVPCYDCGECIAVCPVGALSYKDFAYTANAWELKKIHSTCS
HCSAGCLISYDVRHFDTLGEESKIFRVLNDFYHNPICGAGRFAFDVSSSPKGSTNLKEAQNALKECEAVRIGGDITNEEA
FLIERLRKELDFKIYNQEVYHFQQFLKVLGEVKRPNIEEIKTSNLVVTIGSSIKTENPLVRYAINNALKLNKASLIAMHP
IKDNALANLCRSSFCITHEVGAEEILLGMLLKMLNIESAALKSLEDSKQSIVDEAALKALEEERKKALEQAEQGCSIGEN
KAENQEEDKIEATTPKEENPEENKTEVKEEKIEVPTKTTYLLLEEAGINLETYEKILALLQKSNNTLLVVGEEIYSHKQA
HNIAKMLRLLAQKSAVKLILIPPSANALGIASICQLSEEIFEHEKIVGIRAQGDFTINSDDRVFGKDALSKVDFILPSLN
QLEGTITNVEGRVLPLKPALRFEGYDLSDIMQGFGFVEENLTECTHKLPTEAGFKAIEFDYLTNYFTNDRVNHRGYLLRA
SPFEKSAKECETIECEPIKPLKEKIAFNAYLKYPETQFNNATNKSENLQLKAGVYVSKAFLKKLNKEVGQNITLSKEEEE
LTGVLYLDESLDQEVFVISPSLLKNHSGFFRESVFDSVDLKEQA

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocat

COG id: COG1034

COG function: function code C; NADH dehydrogenase/NADH:ubiquinone oxidoreductase 75 kD subunit (chain G)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 4Fe-4S ferredoxin-type domains [H]

Homologues:

Organism=Homo sapiens, GI33519475, Length=294, Percent_Identity=28.5714285714286, Blast_Score=118, Evalue=2e-26,
Organism=Escherichia coli, GI145693161, Length=441, Percent_Identity=24.9433106575964, Blast_Score=122, Evalue=1e-28,
Organism=Caenorhabditis elegans, GI17565758, Length=293, Percent_Identity=29.0102389078498, Blast_Score=105, Evalue=8e-23,
Organism=Caenorhabditis elegans, GI32566231, Length=293, Percent_Identity=29.0102389078498, Blast_Score=105, Evalue=1e-22,
Organism=Caenorhabditis elegans, GI193209088, Length=245, Percent_Identity=29.7959183673469, Blast_Score=101, Evalue=2e-21,
Organism=Drosophila melanogaster, GI24640559, Length=430, Percent_Identity=24.4186046511628, Blast_Score=103, Evalue=3e-22,
Organism=Drosophila melanogaster, GI24640557, Length=430, Percent_Identity=24.4186046511628, Blast_Score=103, Evalue=3e-22,

Paralogues:

None

Copy number: 60 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017896
- InterPro:   IPR017900
- InterPro:   IPR009010
- InterPro:   IPR012675
- InterPro:   IPR001041
- InterPro:   IPR006657
- InterPro:   IPR006656
- InterPro:   IPR006963
- InterPro:   IPR006655
- InterPro:   IPR000283
- InterPro:   IPR019574 [H]

Pfam domain/function: PF04879 Molybdop_Fe4S4; PF00384 Molybdopterin; PF01568 Molydop_binding; PF10588 NADH-G_4Fe-4S_3 [H]

EC number: =1.6.99.5 [H]

Molecular weight: Translated: 94329; Mature: 94329

Theoretical pI: Translated: 5.08; Mature: 5.08

Prosite motif: PS51085 2FE2S_FER_2 ; PS00198 4FE4S_FERREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.4 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
3.4 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MITMNINGKTIECQEGQSVLEAARSAGIYIPTICYLSGCSPTVACKMCMVEMDGKRVYSC
CEEEECCCCEEECCCCHHHHHHHHHCCCEEEHHHEECCCCHHHHHHHHHEEECCCEEEEE
NTKAKNNATILTNTPTLMDERKSIMQTYDVNHPLECGVCDKSGECELQDMTHLTGVEHQP
CCCCCCCCEEEECCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHCCCCCCC
YAVADDFKALDSWAKALYDPNLCIMCERCVTTCKDNVGENNLKATKADLHAPDKFKDRMS
CCHHHHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHCCCCCCCEECHHCCCCCHHHHHHHH
KDAFSVWSRKQKGIISFVGSVPCYDCGECIAVCPVGALSYKDFAYTANAWELKKIHSTCS
HHHHHHHHHHHCCHHHHHCCCCCCCCCCHHHHCCCCCCCCCCCEEECCCHHHHHHHHHHH
HCSAGCLISYDVRHFDTLGEESKIFRVLNDFYHNPICGAGRFAFDVSSSPKGSTNLKEAQ
HCCCCCEEEECHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCEEEECCCCCCCCCCHHHHH
NALKECEAVRIGGDITNEEAFLIERLRKELDFKIYNQEVYHFQQFLKVLGEVKRPNIEEI
HHHHHCCEEEECCCCCCCHHHHHHHHHHHCCEEEEHHHHHHHHHHHHHHHHCCCCCHHHH
KTSNLVVTIGSSIKTENPLVRYAINNALKLNKASLIAMHPIKDNALANLCRSSFCITHEV
CCCCEEEEECCCCCCCCCEEEEECCCHHEECCCEEEEECCCCCHHHHHHHHHCCEEEECC
GAEEILLGMLLKMLNIESAALKSLEDSKQSIVDEAALKALEEERKKALEQAEQGCSIGEN
CHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
KAENQEEDKIEATTPKEENPEENKTEVKEEKIEVPTKTTYLLLEEAGINLETYEKILALL
CCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCEEEEEEECCCCCHHHHHHHHHHH
QKSNNTLLVVGEEIYSHKQAHNIAKMLRLLAQKSAVKLILIPPSANALGIASICQLSEEI
HCCCCEEEEECHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCHHHHHHHHHHHHH
FEHEKIVGIRAQGDFTINSDDRVFGKDALSKVDFILPSLNQLEGTITNVEGRVLPLKPAL
HHHHHEEEEEECCCEEECCCCCCCCHHHHHHHHHHHCCHHHHCCEEECCCCEEEECCCCC
RFEGYDLSDIMQGFGFVEENLTECTHKLPTEAGFKAIEFDYLTNYFTNDRVNHRGYLLRA
EECCCCHHHHHHHCCHHHHHHHHHHHHCCCCCCCCEEEHHHHHHHHCCCCCCCCCEEEEC
SPFEKSAKECETIECEPIKPLKEKIAFNAYLKYPETQFNNATNKSENLQLKAGVYVSKAF
CCCHHHHHHCCCCCCCCCCHHHHHHHHHHEECCCCHHCCCCCCCCCCEEEECCHHHHHHH
LKKLNKEVGQNITLSKEEEELTGVLYLDESLDQEVFVISPSLLKNHSGFFRESVFDSVDL
HHHHHHHHCCCCCCCCCHHHHEEEEEECCCCCCEEEEECHHHHHCCCCHHHHHHHCCCCC
KEQA
CCCC
>Mature Secondary Structure
MITMNINGKTIECQEGQSVLEAARSAGIYIPTICYLSGCSPTVACKMCMVEMDGKRVYSC
CEEEECCCCEEECCCCHHHHHHHHHCCCEEEHHHEECCCCHHHHHHHHHEEECCCEEEEE
NTKAKNNATILTNTPTLMDERKSIMQTYDVNHPLECGVCDKSGECELQDMTHLTGVEHQP
CCCCCCCCEEEECCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHCCCCCCC
YAVADDFKALDSWAKALYDPNLCIMCERCVTTCKDNVGENNLKATKADLHAPDKFKDRMS
CCHHHHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHCCCCCCCEECHHCCCCCHHHHHHHH
KDAFSVWSRKQKGIISFVGSVPCYDCGECIAVCPVGALSYKDFAYTANAWELKKIHSTCS
HHHHHHHHHHHCCHHHHHCCCCCCCCCCHHHHCCCCCCCCCCCEEECCCHHHHHHHHHHH
HCSAGCLISYDVRHFDTLGEESKIFRVLNDFYHNPICGAGRFAFDVSSSPKGSTNLKEAQ
HCCCCCEEEECHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCEEEECCCCCCCCCCHHHHH
NALKECEAVRIGGDITNEEAFLIERLRKELDFKIYNQEVYHFQQFLKVLGEVKRPNIEEI
HHHHHCCEEEECCCCCCCHHHHHHHHHHHCCEEEEHHHHHHHHHHHHHHHHCCCCCHHHH
KTSNLVVTIGSSIKTENPLVRYAINNALKLNKASLIAMHPIKDNALANLCRSSFCITHEV
CCCCEEEEECCCCCCCCCEEEEECCCHHEECCCEEEEECCCCCHHHHHHHHHCCEEEECC
GAEEILLGMLLKMLNIESAALKSLEDSKQSIVDEAALKALEEERKKALEQAEQGCSIGEN
CHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
KAENQEEDKIEATTPKEENPEENKTEVKEEKIEVPTKTTYLLLEEAGINLETYEKILALL
CCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCEEEEEEECCCCCHHHHHHHHHHH
QKSNNTLLVVGEEIYSHKQAHNIAKMLRLLAQKSAVKLILIPPSANALGIASICQLSEEI
HCCCCEEEEECHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCHHHHHHHHHHHHH
FEHEKIVGIRAQGDFTINSDDRVFGKDALSKVDFILPSLNQLEGTITNVEGRVLPLKPAL
HHHHHEEEEEECCCEEECCCCCCCCHHHHHHHHHHHCCHHHHCCEEECCCCEEEECCCCC
RFEGYDLSDIMQGFGFVEENLTECTHKLPTEAGFKAIEFDYLTNYFTNDRVNHRGYLLRA
EECCCCHHHHHHHCCHHHHHHHHHHHHCCCCCCCCEEEHHHHHHHHCCCCCCCCCEEEEC
SPFEKSAKECETIECEPIKPLKEKIAFNAYLKYPETQFNNATNKSENLQLKAGVYVSKAF
CCCHHHHHHCCCCCCCCCCHHHHHHHHHHEECCCCHHCCCCCCCCCCEEEECCHHHHHHH
LKKLNKEVGQNITLSKEEEELTGVLYLDESLDQEVFVISPSLLKNHSGFFRESVFDSVDL
HHHHHHHHCCCCCCCCCHHHHEEEEEECCCCCCEEEEECHHHHHCCCCHHHHHHHCCCCC
KEQA
CCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11481432 [H]