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The map label for this gene is ruvA [H]

Identifier: 108563288

GI number: 108563288

Start: 898513

End: 899064

Strand: Reverse

Name: ruvA [H]

Synonym: HPAG1_0863

Alternate gene names: 108563288

Gene position: 899064-898513 (Counterclockwise)

Preceding gene: 108563289

Following gene: 108563287

Centisome position: 56.32

GC content: 39.67

Gene sequence:

>552_bases
ATGATAGTGGGTTTGATAGGGGTTGTGGAAAAAATCTCTGCTTTAGAAGCGCATATAGAAGTGCAAGGGGTTGTTTATGG
GGTGCAAGTTTCTATGCGCACTTCTGCTTTGCTTGAAACGGGCCAAAAGGTGCGTTTGAAAATCTTACAAGTAATTAAAG
AAGATGCAAATCTTTTATACGGGTTTTTAGAAGAGAGCGAAAAAATCCTTTTTGAAAGGCTTTTAAAAATCAATGGGGTA
GGGGGTCGTATCGCTTTAGCCATTCTTTCAAGCTTTTCGCCGAATGAATTTGAAAACATTATCGCCACTAAAGAAGTCAA
AAGACTCCAGCAAGTCCCAGGCATTGGCAAAAAGCTCGCTGATAAGATCATGGTGGATCTCATTGGCTTTTTCATTCAAG
ATGAAAATAGACCTGCGCGCAATGAAGTTTTTTTAGCCCTAGAGAGTTTGGGCTTTAAAAGCGCTGAAATCAATAAAGTT
TTAAAAACCCTAAAACCCAATCTCAGCATAGAAGCAGCGATTAAAGAAGCCCTACAACAACTGCGCTCTTAA

Upstream 100 bases:

>100_bases
CATAATGAAAGCGTGAATGTGATCTATGAAGATCATAAAATCAAAAAAGTCCCTAAAAGCGCGATAAAAGGCTAGAACAA
GAAATAAAAAAGGGATAAAA

Downstream 100 bases:

>100_bases
AAAAGTTTTTTAGTATCCGCTCGCTAAAAACCTAGTAAGCAGTTAGACTTGAGTGCAAAAATCACAATTTAGCAACAACA
CGCTTAAAATCATTGAAGAG

Product: Holliday junction DNA helicase RuvA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 183; Mature: 183

Protein sequence:

>183_residues
MIVGLIGVVEKISALEAHIEVQGVVYGVQVSMRTSALLETGQKVRLKILQVIKEDANLLYGFLEESEKILFERLLKINGV
GGRIALAILSSFSPNEFENIIATKEVKRLQQVPGIGKKLADKIMVDLIGFFIQDENRPARNEVFLALESLGFKSAEINKV
LKTLKPNLSIEAAIKEALQQLRS

Sequences:

>Translated_183_residues
MIVGLIGVVEKISALEAHIEVQGVVYGVQVSMRTSALLETGQKVRLKILQVIKEDANLLYGFLEESEKILFERLLKINGV
GGRIALAILSSFSPNEFENIIATKEVKRLQQVPGIGKKLADKIMVDLIGFFIQDENRPARNEVFLALESLGFKSAEINKV
LKTLKPNLSIEAAIKEALQQLRS
>Mature_183_residues
MIVGLIGVVEKISALEAHIEVQGVVYGVQVSMRTSALLETGQKVRLKILQVIKEDANLLYGFLEESEKILFERLLKINGV
GGRIALAILSSFSPNEFENIIATKEVKRLQQVPGIGKKLADKIMVDLIGFFIQDENRPARNEVFLALESLGFKSAEINKV
LKTLKPNLSIEAAIKEALQQLRS

Specific function: The ruvA-ruvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is an helicase that mediates the Holliday

COG id: COG0632

COG function: function code L; Holliday junction resolvasome, DNA-binding subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ruvA family [H]

Homologues:

Organism=Escherichia coli, GI1788168, Length=182, Percent_Identity=37.9120879120879, Blast_Score=101, Evalue=4e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011114
- InterPro:   IPR013849
- InterPro:   IPR003583
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR000085
- InterPro:   IPR010994 [H]

Pfam domain/function: PF07499 RuvA_C; PF01330 RuvA_N [H]

EC number: =3.6.4.12 [H]

Molecular weight: Translated: 20256; Mature: 20256

Theoretical pI: Translated: 9.48; Mature: 9.48

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIVGLIGVVEKISALEAHIEVQGVVYGVQVSMRTSALLETGQKVRLKILQVIKEDANLLY
CEEHHHHHHHHHHHHHHHHEEEEEEEEEEEHHHHHHHHHCCHHHHHHHHHHHHHHHHHHH
GFLEESEKILFERLLKINGVGGRIALAILSSFSPNEFENIIATKEVKRLQQVPGIGKKLA
HHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCHHHHH
DKIMVDLIGFFIQDENRPARNEVFLALESLGFKSAEINKVLKTLKPNLSIEAAIKEALQQ
HHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHH
LRS
HCC
>Mature Secondary Structure
MIVGLIGVVEKISALEAHIEVQGVVYGVQVSMRTSALLETGQKVRLKILQVIKEDANLLY
CEEHHHHHHHHHHHHHHHHEEEEEEEEEEEHHHHHHHHHCCHHHHHHHHHHHHHHHHHHH
GFLEESEKILFERLLKINGVGGRIALAILSSFSPNEFENIIATKEVKRLQQVPGIGKKLA
HHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCHHHHH
DKIMVDLIGFFIQDENRPARNEVFLALESLGFKSAEINKVLKTLKPNLSIEAAIKEALQQ
HHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHH
LRS
HCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA