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The map label for this gene is hcpD [H]

Identifier: 108563035

GI number: 108563035

Start: 637704

End: 638762

Strand: Direct

Name: hcpD [H]

Synonym: HPAG1_0610

Alternate gene names: 108563035

Gene position: 637704-638762 (Clockwise)

Preceding gene: 108563034

Following gene: 108563036

Centisome position: 39.95

GC content: 43.72

Gene sequence:

>1059_bases
ATGCTCAAAAAAAGTTTGTTATTGCTTGTTTTTTTAATCTTACAGCTTAGCGGTGCTGAAGAAAACAATCAAGCCCCAAA
AAACACGCCCCCTGAATTAAACCCCGCTAACGCTAAGGGCGCACCAAACCCTAACACCCAAATCACCCCTAAAAACGATA
ACTCTAATCTGTTAGACAAATTAGGATCGCCTGAAAACGCTCAAACCGAGCTTTCTGCCGGTATTGAATTGGCTAAAAAG
GGCGATTATCAAGGGGCTTTCAAGCTTTTTTCCCAATCGTGCGATAATGGTAATGCGGCCGGGTGTTTTGCGGTGGGGGC
GATGTATGCTAATGGGGTAGGGATCCAAACCAACAGATTAAAAGCCGCTCGCTATTATGAAATGGGTTGCAGTGGGGGCG
ATGCGACCGCTTGCGCGAATCTGGCTCAAATGTATGAAAACAAAAAAAACGCTGATTCAAACGATAAAGAAAACGCTTTG
CAATTGTATGCGGTGGCTTGTCAAGGGGGGGACATGCTCGCATGCAATAATTTGGGGTGGATGTTTGCTAATGGGAGTGG
GGTCCCAAAAGATTATTACAAAGCGATAAGTTATTATAAATTTTCATGCGAAAACGGGAATGATATGGGGTGCTATAATT
TGGGCTTGATGTCTAATGTGAATAATATTTATGGCATTGATAAGGCCAAGCTCAGTCAAGTGGATTTGAATTATTTGGCT
TGTAACGCTGGGGATATGATGGGGTGCGCGAATTTAGGCTGGATTTATGCGAATGGGGATTTAGGGGCTCCTTTGAATAA
CCACTACGCAGCGAAATATTTTCAAATGGCATGCGATGGGGGGATTTTGGGGAGCTGTAATAATTTAGGCGTGCTGTATC
AAAAGGGCTTAGGCGTGCCTCAAGACGATCAAAGGGCGTTGGATTTATTCTCGTATGCGTGCGATAATGGTTTTGAGTCA
AGCTGTCGTAATTACGGGAATTTCAAAGAGCATTTATTGCGCGTGAACCCTAATTACGGGCGCTTGTTCATGCCATATAA
TTCTTATGAGATACCCTAG

Upstream 100 bases:

>100_bases
GCGTGCATTTTCGTTCCAATAGCCAGAATGGCAAGCTGATCGCTTTTAGGAGCGTGAAAAAAATTGAGTTGAATCAAAAC
CTGCATTAAGGATTAAAAGA

Downstream 100 bases:

>100_bases
TAATAGCAATTTTTTAAGAGAATAGGGGGTATTTTGAAATCATTCTCGCTCCCATTAACTAAACCCCCCAAAAGATCGCA
TTTTTAAGAGGTTAGCGTTT

Product: hypothetical protein

Products: NA

Alternate protein names: Cysteine-rich protein D; Penicillin-binding protein 4; PBP 4 [H]

Number of amino acids: Translated: 352; Mature: 352

Protein sequence:

>352_residues
MLKKSLLLLVFLILQLSGAEENNQAPKNTPPELNPANAKGAPNPNTQITPKNDNSNLLDKLGSPENAQTELSAGIELAKK
GDYQGAFKLFSQSCDNGNAAGCFAVGAMYANGVGIQTNRLKAARYYEMGCSGGDATACANLAQMYENKKNADSNDKENAL
QLYAVACQGGDMLACNNLGWMFANGSGVPKDYYKAISYYKFSCENGNDMGCYNLGLMSNVNNIYGIDKAKLSQVDLNYLA
CNAGDMMGCANLGWIYANGDLGAPLNNHYAAKYFQMACDGGILGSCNNLGVLYQKGLGVPQDDQRALDLFSYACDNGFES
SCRNYGNFKEHLLRVNPNYGRLFMPYNSYEIP

Sequences:

>Translated_352_residues
MLKKSLLLLVFLILQLSGAEENNQAPKNTPPELNPANAKGAPNPNTQITPKNDNSNLLDKLGSPENAQTELSAGIELAKK
GDYQGAFKLFSQSCDNGNAAGCFAVGAMYANGVGIQTNRLKAARYYEMGCSGGDATACANLAQMYENKKNADSNDKENAL
QLYAVACQGGDMLACNNLGWMFANGSGVPKDYYKAISYYKFSCENGNDMGCYNLGLMSNVNNIYGIDKAKLSQVDLNYLA
CNAGDMMGCANLGWIYANGDLGAPLNNHYAAKYFQMACDGGILGSCNNLGVLYQKGLGVPQDDQRALDLFSYACDNGFES
SCRNYGNFKEHLLRVNPNYGRLFMPYNSYEIP
>Mature_352_residues
MLKKSLLLLVFLILQLSGAEENNQAPKNTPPELNPANAKGAPNPNTQITPKNDNSNLLDKLGSPENAQTELSAGIELAKK
GDYQGAFKLFSQSCDNGNAAGCFAVGAMYANGVGIQTNRLKAARYYEMGCSGGDATACANLAQMYENKKNADSNDKENAL
QLYAVACQGGDMLACNNLGWMFANGSGVPKDYYKAISYYKFSCENGNDMGCYNLGLMSNVNNIYGIDKAKLSQVDLNYLA
CNAGDMMGCANLGWIYANGDLGAPLNNHYAAKYFQMACDGGILGSCNNLGVLYQKGLGVPQDDQRALDLFSYACDNGFES
SCRNYGNFKEHLLRVNPNYGRLFMPYNSYEIP

Specific function: May hydrolyze 6-aminopenicillinic acid and 7- aminocephalosporanic acid (ACA) derivatives. Binds to penicillin [H]

COG id: COG0790

COG function: function code R; FOG: TPR repeat, SEL1 subfamily

Gene ontology:

Cell location: Secreted [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 4 TPR repeats [H]

Homologues:

Organism=Homo sapiens, GI19923669, Length=291, Percent_Identity=26.4604810996564, Blast_Score=77, Evalue=3e-14,
Organism=Homo sapiens, GI151301150, Length=252, Percent_Identity=26.984126984127, Blast_Score=69, Evalue=8e-12,
Organism=Escherichia coli, GI87081769, Length=234, Percent_Identity=23.9316239316239, Blast_Score=64, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17563256, Length=262, Percent_Identity=25.5725190839695, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI21355295, Length=273, Percent_Identity=25.6410256410256, Blast_Score=71, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006597
- InterPro:   IPR011990 [H]

Pfam domain/function: PF08238 Sel1 [H]

EC number: =3.5.2.6 [H]

Molecular weight: Translated: 38070; Mature: 38070

Theoretical pI: Translated: 4.97; Mature: 4.97

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

4.0 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
7.4 %Cys+Met (Translated Protein)
4.0 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
7.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLKKSLLLLVFLILQLSGAEENNQAPKNTPPELNPANAKGAPNPNTQITPKNDNSNLLDK
CCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEECCCCCCHHHHH
LGSPENAQTELSAGIELAKKGDYQGAFKLFSQSCDNGNAAGCFAVGAMYANGVGIQTNRL
CCCCCCCHHHHHHCCHHHHCCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCCCCCCE
KAARYYEMGCSGGDATACANLAQMYENKKNADSNDKENALQLYAVACQGGDMLACNNLGW
EHHHHEECCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCEEEEEEEEECCCCEEEECCCCE
MFANGSGVPKDYYKAISYYKFSCENGNDMGCYNLGLMSNVNNIYGIDKAKLSQVDLNYLA
EEECCCCCCHHHHHHHHHEEEECCCCCCCCEEECHHHHCCCHHCCCCHHHHHHCCCEEEE
CNAGDMMGCANLGWIYANGDLGAPLNNHYAAKYFQMACDGGILGSCNNLGVLYQKGLGVP
ECCCCCCCCCCCCEEEECCCCCCCCCCCHHHHHHHHHCCCCEEECCCCCCHHHCCCCCCC
QDDQRALDLFSYACDNGFESSCRNYGNFKEHLLRVNPNYGRLFMPYNSYEIP
CCHHHHHHHHHHHHCCCHHHHHHHCCCHHHHHEEECCCCCEEEECCCCCCCC
>Mature Secondary Structure
MLKKSLLLLVFLILQLSGAEENNQAPKNTPPELNPANAKGAPNPNTQITPKNDNSNLLDK
CCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEECCCCCCHHHHH
LGSPENAQTELSAGIELAKKGDYQGAFKLFSQSCDNGNAAGCFAVGAMYANGVGIQTNRL
CCCCCCCHHHHHHCCHHHHCCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCCCCCCE
KAARYYEMGCSGGDATACANLAQMYENKKNADSNDKENALQLYAVACQGGDMLACNNLGW
EHHHHEECCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCEEEEEEEEECCCCEEEECCCCE
MFANGSGVPKDYYKAISYYKFSCENGNDMGCYNLGLMSNVNNIYGIDKAKLSQVDLNYLA
EEECCCCCCHHHHHHHHHEEEECCCCCCCCEEECHHHHCCCHHCCCCHHHHHHCCCEEEE
CNAGDMMGCANLGWIYANGDLGAPLNNHYAAKYFQMACDGGILGSCNNLGVLYQKGLGVP
ECCCCCCCCCCCCEEEECCCCCCCCCCCHHHHHHHHHCCCCEEECCCCCCHHHCCCCCCC
QDDQRALDLFSYACDNGFESSCRNYGNFKEHLLRVNPNYGRLFMPYNSYEIP
CCHHHHHHHHHHHHCCCHHHHHHHCCCHHHHHEEECCCCCEEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9252185; 10438788 [H]