Click here to switch to the map view.

The map label for this gene is ruvB [H]

Identifier: 108562813

GI number: 108562813

Start: 397668

End: 398678

Strand: Reverse

Name: ruvB [H]

Synonym: HPAG1_0388

Alternate gene names: 108562813

Gene position: 398678-397668 (Counterclockwise)

Preceding gene: 108562814

Following gene: 108562812

Centisome position: 24.97

GC content: 41.84

Gene sequence:

>1011_bases
ATGAAAGAACGGATAGTCAATTTAGAAACTTTGGATTTTGAAACTTCTCAAGAAGTGAGTTTGCGCCCTAGTCTTTGGGA
AGATTTTATTGGTCAAGAAAAGATTAAAAGCAACTTGCAAATTTCTATTTGCGCGGCTAAAAAACGCCAAGAAAGTTTGG
ATCACATGCTCTTTTTTGGCCCGCCCGGTTTGGGTAAAACTTCAATCAGCCATATCATCGCTAAAGAAATGGAAACCAAT
ATCAAAATCACCGCCGCTCCCATGATAGAAAAAAGCGGTGATTTGGCCGCCATTTTGACGAATTTGCAAGCTAAAGACAT
TCTTTTTATTGACGAAATCCACCGGCTCAGCCCAGCAATTGAAGAGGTTTTATACCCGGCGATGGAAGATTTTAGGTTGG
ATATTATCATAGGCTCAGGCCCAGCCGCTCAAACCATTAAGATTGATTTACCCCCTTTCACCCTCATCGGCGCTACCACT
AGAGCCGGAATGCTCTCTAACCCCTTAAGAGACAGATTTGGCATGAGTTTTAGGATGCAATTTTATAGCCCTAGCGAATT
AGCCCTTATCATCAAAAAAGCCGCCATTAAACTCAACCAAGACATCAAAGAAGAAAGCGCTGATGAAATCGCTAAAAGGA
GTAGAGGCACGCCAAGGATCGCTTTAAGGCTTTTAAAAAGGGTGCGCGATTTTGCGTTAGTCAAAAATTCAAGCTTGATG
GATTTAAACATCACTTTGCATGCTTTGAATGAATTAGGCGTGAATGAATTGGGCTTTGATGAGGCGGATTTGGCGTATTT
ATCTTTGTTGGCTAACGCTCAAGGACGGCCGGTGGGTTTGAACACGATTGCAGCATCTATGAGAGAAGATGAAGGCACGA
TTGAAGACGTGATTGAGCCTTTTTTACTCGCTAATGGTTATTTAGAGCGCACCGCTAAAGGCAGAATTGCTACGCCCAAA
ACCCATGCACTTTTAAAAATCCCCACTTTAAAGTCTCAAACTTTATTTTAA

Upstream 100 bases:

>100_bases
ATACCTTAAAGGGAAAGAATTGGTTCAAAACGCTATCAAGCAATACGCTGATGATGTGAAAAAGGGAAACTTCCCTAACG
AATTAGAAAGTTACCATTAA

Downstream 100 bases:

>100_bases
TCTTGTTTAGAAAGAAAATTACACTACAATAACGATAAAATTTTAAAGGGTGTAAAAGTAGATTATTATGTTTGGCATGG
GCTTTTTTGAAATCCTTGTG

Product: Holliday junction DNA helicase RuvB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 336; Mature: 336

Protein sequence:

>336_residues
MKERIVNLETLDFETSQEVSLRPSLWEDFIGQEKIKSNLQISICAAKKRQESLDHMLFFGPPGLGKTSISHIIAKEMETN
IKITAAPMIEKSGDLAAILTNLQAKDILFIDEIHRLSPAIEEVLYPAMEDFRLDIIIGSGPAAQTIKIDLPPFTLIGATT
RAGMLSNPLRDRFGMSFRMQFYSPSELALIIKKAAIKLNQDIKEESADEIAKRSRGTPRIALRLLKRVRDFALVKNSSLM
DLNITLHALNELGVNELGFDEADLAYLSLLANAQGRPVGLNTIAASMREDEGTIEDVIEPFLLANGYLERTAKGRIATPK
THALLKIPTLKSQTLF

Sequences:

>Translated_336_residues
MKERIVNLETLDFETSQEVSLRPSLWEDFIGQEKIKSNLQISICAAKKRQESLDHMLFFGPPGLGKTSISHIIAKEMETN
IKITAAPMIEKSGDLAAILTNLQAKDILFIDEIHRLSPAIEEVLYPAMEDFRLDIIIGSGPAAQTIKIDLPPFTLIGATT
RAGMLSNPLRDRFGMSFRMQFYSPSELALIIKKAAIKLNQDIKEESADEIAKRSRGTPRIALRLLKRVRDFALVKNSSLM
DLNITLHALNELGVNELGFDEADLAYLSLLANAQGRPVGLNTIAASMREDEGTIEDVIEPFLLANGYLERTAKGRIATPK
THALLKIPTLKSQTLF
>Mature_336_residues
MKERIVNLETLDFETSQEVSLRPSLWEDFIGQEKIKSNLQISICAAKKRQESLDHMLFFGPPGLGKTSISHIIAKEMETN
IKITAAPMIEKSGDLAAILTNLQAKDILFIDEIHRLSPAIEEVLYPAMEDFRLDIIIGSGPAAQTIKIDLPPFTLIGATT
RAGMLSNPLRDRFGMSFRMQFYSPSELALIIKKAAIKLNQDIKEESADEIAKRSRGTPRIALRLLKRVRDFALVKNSSLM
DLNITLHALNELGVNELGFDEADLAYLSLLANAQGRPVGLNTIAASMREDEGTIEDVIEPFLLANGYLERTAKGRIATPK
THALLKIPTLKSQTLF

Specific function: The ruvA-ruvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is an helicase that mediates the Holliday

COG id: COG2255

COG function: function code L; Holliday junction resolvasome, helicase subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ruvB family [H]

Homologues:

Organism=Escherichia coli, GI1788167, Length=319, Percent_Identity=52.0376175548589, Blast_Score=346, Evalue=1e-96,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR004605
- InterPro:   IPR008823
- InterPro:   IPR008824
- InterPro:   IPR011991
- ProDom:   PD005323 [H]

Pfam domain/function: PF05491 RuvB_C; PF05496 RuvB_N [H]

EC number: =3.6.4.12 [H]

Molecular weight: Translated: 37311; Mature: 37311

Theoretical pI: Translated: 6.39; Mature: 6.39

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKERIVNLETLDFETSQEVSLRPSLWEDFIGQEKIKSNLQISICAAKKRQESLDHMLFFG
CCCCEEEEEEECCCCCCCCCCCCHHHHHHCCHHHHHCCCEEEEEECHHHHHHHCCEEEEC
PPGLGKTSISHIIAKEMETNIKITAAPMIEKSGDLAAILTNLQAKDILFIDEIHRLSPAI
CCCCCHHHHHHHHHHHHHCCEEEEEECCCCCCCCCEEHHHCCCCCCCHHHHHHHHHHHHH
EEVLYPAMEDFRLDIIIGSGPAAQTIKIDLPPFTLIGATTRAGMLSNPLRDRFGMSFRMQ
HHHHHHHHHCEEEEEEECCCCCCEEEEEECCCEEEEECCHHCCHHCCHHHHHHCCEEEEE
FYSPSELALIIKKAAIKLNQDIKEESADEIAKRSRGTPRIALRLLKRVRDFALVKNSSLM
EECCCHHHHHHHHHHHHHCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCEE
DLNITLHALNELGVNELGFDEADLAYLSLLANAQGRPVGLNTIAASMREDEGTIEDVIEP
EEEEEEEEHHHCCCCCCCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCCHHHHHHH
FLLANGYLERTAKGRIATPKTHALLKIPTLKSQTLF
HHHHCCHHHHHCCCCCCCCCCCEEEEECCCCCCCCC
>Mature Secondary Structure
MKERIVNLETLDFETSQEVSLRPSLWEDFIGQEKIKSNLQISICAAKKRQESLDHMLFFG
CCCCEEEEEEECCCCCCCCCCCCHHHHHHCCHHHHHCCCEEEEEECHHHHHHHCCEEEEC
PPGLGKTSISHIIAKEMETNIKITAAPMIEKSGDLAAILTNLQAKDILFIDEIHRLSPAI
CCCCCHHHHHHHHHHHHHCCEEEEEECCCCCCCCCEEHHHCCCCCCCHHHHHHHHHHHHH
EEVLYPAMEDFRLDIIIGSGPAAQTIKIDLPPFTLIGATTRAGMLSNPLRDRFGMSFRMQ
HHHHHHHHHCEEEEEEECCCCCCEEEEEECCCEEEEECCHHCCHHCCHHHHHHCCEEEEE
FYSPSELALIIKKAAIKLNQDIKEESADEIAKRSRGTPRIALRLLKRVRDFALVKNSSLM
EECCCHHHHHHHHHHHHHCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCEE
DLNITLHALNELGVNELGFDEADLAYLSLLANAQGRPVGLNTIAASMREDEGTIEDVIEP
EEEEEEEEHHHCCCCCCCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCCHHHHHHH
FLLANGYLERTAKGRIATPKTHALLKIPTLKSQTLF
HHHHCCHHHHHCCCCCCCCCCCEEEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA