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The map label for this gene is argS [H]

Identifier: 108562747

GI number: 108562747

Start: 334685

End: 336310

Strand: Reverse

Name: argS [H]

Synonym: HPAG1_0322

Alternate gene names: 108562747

Gene position: 336310-334685 (Counterclockwise)

Preceding gene: 108562748

Following gene: 108562746

Centisome position: 21.07

GC content: 38.07

Gene sequence:

>1626_bases
ATGCACACTCTCATTAAGGGCGTTTTAGAAGAGATTTTAGAAGAAGAAGTCATTATTGAATACCCTAAAGACAGAGAGCA
TGGGCATTACGCTACGCCCATTGCTTTCAATCTCGCCAAAGTTTTTAAAAAATCGCCCCTAGTTATCGCTGAAGAGTTAG
CCCTTAAAATCAGCACGCATGAAAAAACTCAAGGGCTTTTTGACAGCATAGTGGCTTGTAAGGGCTATATCAATTTCACG
CTTTCTTTAGATCTTTTAGAGCGTTTCACCCAAAAGGCTTTAGAATTAAAAGAACAATTTGGCTCTCAAATTAAAAGCGA
ACGTTCTCAAAAAATCTTTTTAGAATTTGTGAGCGCTAACCCCACAGGGCCTTTACACATAGGGCATGCTAGAGGGGCGG
TGTTTGGCGATAGTTTGGCTAAAATCGCTCGCTTTTTAGGGCATGAAGTTTTATGCGAATATTATGTTAATGACATGGGA
TCTCAAATCCGCTTGTTAGGGCTTTCGGTATGGCTCGCTTACAGAGAGCATGTTTTAAAAGAAAACGTAACTTACCCAGA
AGTCTTTTACAAAGGCGAATACATCATTGAAATCGCTAAAAAAGCGAACAACGATTTAGAGCCAAGCCTTTTTAAAGAAA
ACGAAGAAACTATTATTGAAGTTTTAAGCGGCTACGCTAAGGATCTAATGCTTTTAGAAATTAAAGATAATTTAGACGCT
TTAGGCATTCATTTTGATTCCTATGCGAGCGAAAAAGAAATTTTTAAACATAAGGATGCGGTGTTTGAACGATTAGAAAA
AGCGAACGCCCTTTATGAAAAAGATTCTAAAATCTGGCTCAAATCTTCACTCTACCAGGATGAAAGCGATCGGGTGCTCA
TTAAAGAAGATAAGAGCTACACTTATCTAACCGGCGATATTGTCTATCACGATGAAAAATTCAAGCAAGATTACACCAAA
TACATCAACATTTGGGGGGCAGACCACCACGGCTATATCGCTAGAGTGAAAGCCAGCCTTGAGTTTTTGGGCTATGATTC
CAATAAGCTTGAAGTCTTACTCGCTCAAATGGTGCGCTTGCTCAAAGATAACGAGCCTTACAAGATGAGTAAAAGAGCGG
GTAATTTCATTTTGATTAAAGATGTGATTGATGATGTGGGTAAGGACGCTTTGAGGTTTATTTTTTTAAGCAAACGGCTT
GACACTCATTTAGAATTTGATGTCAATACCTTAAAAAAGCAAGACAGCTCAAACCCCATTTACTATATCCATTACGCTAA
TTCGCGCATCCACACCATGCTAGAAAAATCGCCCTTTTCTAAAGAAGAGGTTTTGCAAACCCCTTTAAAAAATTTAAACG
CTGAAGAAAAATACCTGCTTTTTAGCACTTTAAGCTTGCCTAAAGCAATTGAATCCTCTTTTGAAGAATACGGCTTGCAA
AAAATGTGCGAATACGCAAAAACTCTCGCCTCAGAATTCCACCGCTTCTATAACGCTGGCAAAATCTTAGACACCCCTAA
AGCTAAGGAGCTTTTAAAAATTTGTTTAATGGTGAGTTTGAGTTTGACTAACGCTTTCAAACTTTTAGGCATAGAGATAA
AAACCAAAATTTCCGCTAAAGATTAA

Upstream 100 bases:

>100_bases
AAGAAGAAGCTAAAAACGAGCCAAAAACCCTAGACGCTCAAGCAACGCAAACCAAAGTGCATGAAACTAGCGAGATTAAA
AGCAAACAAGAAAGTTAAAC

Downstream 100 bases:

>100_bases
GCTCAAAATTAGTTTTTTTGATTATAATACTCTCATTATTTTCAAAAAATAAGGAGAATGTTTTGCTTAATCGTATTATA
GAACACATGAACGCTCACCA

Product: arginyl-tRNA synthetase

Products: NA

Alternate protein names: Arginine--tRNA ligase; ArgRS [H]

Number of amino acids: Translated: 541; Mature: 541

Protein sequence:

>541_residues
MHTLIKGVLEEILEEEVIIEYPKDREHGHYATPIAFNLAKVFKKSPLVIAEELALKISTHEKTQGLFDSIVACKGYINFT
LSLDLLERFTQKALELKEQFGSQIKSERSQKIFLEFVSANPTGPLHIGHARGAVFGDSLAKIARFLGHEVLCEYYVNDMG
SQIRLLGLSVWLAYREHVLKENVTYPEVFYKGEYIIEIAKKANNDLEPSLFKENEETIIEVLSGYAKDLMLLEIKDNLDA
LGIHFDSYASEKEIFKHKDAVFERLEKANALYEKDSKIWLKSSLYQDESDRVLIKEDKSYTYLTGDIVYHDEKFKQDYTK
YINIWGADHHGYIARVKASLEFLGYDSNKLEVLLAQMVRLLKDNEPYKMSKRAGNFILIKDVIDDVGKDALRFIFLSKRL
DTHLEFDVNTLKKQDSSNPIYYIHYANSRIHTMLEKSPFSKEEVLQTPLKNLNAEEKYLLFSTLSLPKAIESSFEEYGLQ
KMCEYAKTLASEFHRFYNAGKILDTPKAKELLKICLMVSLSLTNAFKLLGIEIKTKISAKD

Sequences:

>Translated_541_residues
MHTLIKGVLEEILEEEVIIEYPKDREHGHYATPIAFNLAKVFKKSPLVIAEELALKISTHEKTQGLFDSIVACKGYINFT
LSLDLLERFTQKALELKEQFGSQIKSERSQKIFLEFVSANPTGPLHIGHARGAVFGDSLAKIARFLGHEVLCEYYVNDMG
SQIRLLGLSVWLAYREHVLKENVTYPEVFYKGEYIIEIAKKANNDLEPSLFKENEETIIEVLSGYAKDLMLLEIKDNLDA
LGIHFDSYASEKEIFKHKDAVFERLEKANALYEKDSKIWLKSSLYQDESDRVLIKEDKSYTYLTGDIVYHDEKFKQDYTK
YINIWGADHHGYIARVKASLEFLGYDSNKLEVLLAQMVRLLKDNEPYKMSKRAGNFILIKDVIDDVGKDALRFIFLSKRL
DTHLEFDVNTLKKQDSSNPIYYIHYANSRIHTMLEKSPFSKEEVLQTPLKNLNAEEKYLLFSTLSLPKAIESSFEEYGLQ
KMCEYAKTLASEFHRFYNAGKILDTPKAKELLKICLMVSLSLTNAFKLLGIEIKTKISAKD
>Mature_541_residues
MHTLIKGVLEEILEEEVIIEYPKDREHGHYATPIAFNLAKVFKKSPLVIAEELALKISTHEKTQGLFDSIVACKGYINFT
LSLDLLERFTQKALELKEQFGSQIKSERSQKIFLEFVSANPTGPLHIGHARGAVFGDSLAKIARFLGHEVLCEYYVNDMG
SQIRLLGLSVWLAYREHVLKENVTYPEVFYKGEYIIEIAKKANNDLEPSLFKENEETIIEVLSGYAKDLMLLEIKDNLDA
LGIHFDSYASEKEIFKHKDAVFERLEKANALYEKDSKIWLKSSLYQDESDRVLIKEDKSYTYLTGDIVYHDEKFKQDYTK
YINIWGADHHGYIARVKASLEFLGYDSNKLEVLLAQMVRLLKDNEPYKMSKRAGNFILIKDVIDDVGKDALRFIFLSKRL
DTHLEFDVNTLKKQDSSNPIYYIHYANSRIHTMLEKSPFSKEEVLQTPLKNLNAEEKYLLFSTLSLPKAIESSFEEYGLQ
KMCEYAKTLASEFHRFYNAGKILDTPKAKELLKICLMVSLSLTNAFKLLGIEIKTKISAKD

Specific function: Unknown

COG id: COG0018

COG function: function code J; Arginyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family [H]

Homologues:

Organism=Homo sapiens, GI15149476, Length=602, Percent_Identity=21.9269102990033, Blast_Score=76, Evalue=9e-14,
Organism=Homo sapiens, GI197100773, Length=328, Percent_Identity=25.3048780487805, Blast_Score=73, Evalue=6e-13,
Organism=Caenorhabditis elegans, GI71985061, Length=606, Percent_Identity=21.2871287128713, Blast_Score=80, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI71985068, Length=588, Percent_Identity=21.5986394557823, Blast_Score=74, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6321883, Length=555, Percent_Identity=21.981981981982, Blast_Score=84, Evalue=7e-17,

Paralogues:

None

Copy number: 789 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 800 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001412
- InterPro:   IPR001278
- InterPro:   IPR015945
- InterPro:   IPR005148
- InterPro:   IPR008909
- InterPro:   IPR014729
- InterPro:   IPR009080 [H]

Pfam domain/function: PF03485 Arg_tRNA_synt_N; PF05746 DALR_1; PF00750 tRNA-synt_1d [H]

EC number: =6.1.1.19 [H]

Molecular weight: Translated: 62280; Mature: 62280

Theoretical pI: Translated: 6.47; Mature: 6.47

Prosite motif: PS00178 AA_TRNA_LIGASE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHTLIKGVLEEILEEEVIIEYPKDREHGHYATPIAFNLAKVFKKSPLVIAEELALKISTH
CHHHHHHHHHHHHCCCEEEECCCCCCCCCCCCHHHHHHHHHHCCCCCEEEHHHHHEEECC
EKTQGLFDSIVACKGYINFTLSLDLLERFTQKALELKEQFGSQIKSERSQKIFLEFVSAN
HHHHHHHHHHHHHCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCC
PTGPLHIGHARGAVFGDSLAKIARFLGHEVLCEYYVNDMGSQIRLLGLSVWLAYREHVLK
CCCCEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEHHHHHHHHHHHHHHHH
ENVTYPEVFYKGEYIIEIAKKANNDLEPSLFKENEETIIEVLSGYAKDLMLLEIKDNLDA
CCCCCCHHEECCHHEEEEHHHCCCCCCCHHHCCCHHHHHHHHHHHHHHEEEEEECCCCCE
LGIHFDSYASEKEIFKHKDAVFERLEKANALYEKDSKIWLKSSLYQDESDRVLIKEDKSY
EEEEHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEHHHCCCCCCCEEEEEECCCE
TYLTGDIVYHDEKFKQDYTKYINIWGADHHGYIARVKASLEFLGYDSNKLEVLLAQMVRL
EEEEEEEEECCHHHHHHHHHHEEEECCCCCCCCEEEEEHHHEECCCCCHHHHHHHHHHHH
LKDNEPYKMSKRAGNFILIKDVIDDVGKDALRFIFLSKRLDTHLEFDVNTLKKQDSSNPI
HCCCCCCCHHHCCCCEEEEHHHHHHHHHHHHHHHHHHHHHCCCEEECHHHHHCCCCCCCE
YYIHYANSRIHTMLEKSPFSKEEVLQTPLKNLNAEEKYLLFSTLSLPKAIESSFEEYGLQ
EEEEECCCHHHHHHHCCCCCHHHHHHHHHHHCCCCCCEEEEEHHCCHHHHHHHHHHHHHH
KMCEYAKTLASEFHRFYNAGKILDTPKAKELLKICLMVSLSLTNAFKLLGIEIKTKISAK
HHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHEEEEEEEECCCC
D
C
>Mature Secondary Structure
MHTLIKGVLEEILEEEVIIEYPKDREHGHYATPIAFNLAKVFKKSPLVIAEELALKISTH
CHHHHHHHHHHHHCCCEEEECCCCCCCCCCCCHHHHHHHHHHCCCCCEEEHHHHHEEECC
EKTQGLFDSIVACKGYINFTLSLDLLERFTQKALELKEQFGSQIKSERSQKIFLEFVSAN
HHHHHHHHHHHHHCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCC
PTGPLHIGHARGAVFGDSLAKIARFLGHEVLCEYYVNDMGSQIRLLGLSVWLAYREHVLK
CCCCEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEHHHHHHHHHHHHHHHH
ENVTYPEVFYKGEYIIEIAKKANNDLEPSLFKENEETIIEVLSGYAKDLMLLEIKDNLDA
CCCCCCHHEECCHHEEEEHHHCCCCCCCHHHCCCHHHHHHHHHHHHHHEEEEEECCCCCE
LGIHFDSYASEKEIFKHKDAVFERLEKANALYEKDSKIWLKSSLYQDESDRVLIKEDKSY
EEEEHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEHHHCCCCCCCEEEEEECCCE
TYLTGDIVYHDEKFKQDYTKYINIWGADHHGYIARVKASLEFLGYDSNKLEVLLAQMVRL
EEEEEEEEECCHHHHHHHHHHEEEECCCCCCCCEEEEEHHHEECCCCCHHHHHHHHHHHH
LKDNEPYKMSKRAGNFILIKDVIDDVGKDALRFIFLSKRLDTHLEFDVNTLKKQDSSNPI
HCCCCCCCHHHCCCCEEEEHHHHHHHHHHHHHHHHHHHHHCCCEEECHHHHHCCCCCCCE
YYIHYANSRIHTMLEKSPFSKEEVLQTPLKNLNAEEKYLLFSTLSLPKAIESSFEEYGLQ
EEEEECCCHHHHHHHCCCCCHHHHHHHHHHHCCCCCCEEEEEHHCCHHHHHHHHHHHHHH
KMCEYAKTLASEFHRFYNAGKILDTPKAKELLKICLMVSLSLTNAFKLLGIEIKTKISAK
HHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHEEEEEEEECCCC
D
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA