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The map label for this gene is htpG [H]

Identifier: 108562636

GI number: 108562636

Start: 213091

End: 214956

Strand: Direct

Name: htpG [H]

Synonym: HPAG1_0211

Alternate gene names: 108562636

Gene position: 213091-214956 (Clockwise)

Preceding gene: 108562635

Following gene: 108562640

Centisome position: 13.35

GC content: 37.57

Gene sequence:

>1866_bases
ATGTCTAATCAAGAATACACCTTTCAAACTGAAATCAACCAGCTTTTGGATTTGATGATCCACTCTTTGTATTCCAATAA
AGAGATTTTTTTAAGAGAGTTGATTTCTAACGCGAGCGACGCTTTGGACAAGCTGAATTATTTAATGCTGACCGATGAGA
AATTAAAAGGGCTGAATATTACGCCTAGCATTCATTTGAGCTTTGATAGCCAGAAAAAAACCTTAACGATTAAAGATAAT
GGTATAGGCATGGATAAAAACGATCTCATTGAGCATCTAGGCACGATCGCCAAATCAGGCACGAAGAGTTTTTTAAGCGC
TTTGAGTGGGGATAAGAAAAAAGATAGCGCCTTGATTGGCCAGTTTGGCGTGGGCTTTTATTCGGCGTTTATGGTAGCGA
GTAAGATTGTCGTTCAAACCAAGAAAGTTACTAATCATCAAGCTTATGCATGGGTGAGCGATGGTAAGGGCAAGTTTGAA
ATCAGCGAATGCGTCAAAGAGGAGCAAGGCACAGAAATCACCCTCTTTTTAAAAGAAGAAGATTCTCATTTTGCGAGCCG
TTGGGAGATTGATGGCATTGTTAAAAAGTATTCTGAGCATATCCCTTTCCCTATTTTTTTAACTTACACCGATACGAAAT
TTGAGGGCGAAGGGGATCATAAAAAAGAAGTTAAAGAAGAAAAATGCGATCAGATCAATCAAGCGAGCGCTTTATGGAAA
ATGAATAAGAGCGAATTAAAAGACAAGGATTACAAAGACTTTTACCAATCGTTTGCACATGACAACAGCGAGCCTTTGAG
CTATATCCATAATAAAGTGGAAGGCTCTTTAGAATACACAACGCTTTTTTATATTCCTAGCAAAGCACCCTTTGACATGT
TTAGGGTGGATTATAAAAGCGGGGTCAAACTTTATGTTAAAAGGGTGTTTATCACTGATGATGACAAAGAATTGTTGCCC
TCTTATTTGAGGTTTGTTAAAGGCGTGATTGACAGCGAAGATTTACCCTTGAACGTGAGCCGTGAAATCTTGCAACAAAA
CAAGATTTTAGCCAATATCCGTTCGGCTTCAGTGAAAAAGATTTTAAGCGAGATTGAACGCTTGAGCAAGGATGAAAAAA
ATTACCATAAATTCTATGAGCCTTTTGGGAAAGTGTTAAAAGAAGGCTTGTATGGGGATTTTGAAAACAAAGAAAAACTT
TTAGAATTGTTAAGATTCTATTCTAAAGACAAAGAAAAATTAATTTCTTTAAAAGAATACAGAGAAAATTTAAAAGAAAA
TCAAAAAAGCATTTACTACCTTTTGGGCGAAAATTTAGACTTATTAAAGGCGTCCCCGCTTTTAGAAAAATACGCTCAAA
AAGGCTATGATGTTTTGTTATTGAGCGATGAGATTGATGCGTTTGTGATGCCAGGCGTGAATGAATACGATAAAACGCCC
TTTAGAGACGCTAGCCATAGCGAGAGTTTGAAAGAGCTTGGTTTGGAAGAAATCAACGATGAGGTAAAAGATCAGTTTAA
AGATTTAATGAAAGCGTTTGAAGAAAATCTTAAAGATGAGATTAAAGGCGTGGAGCTTTCTAGCCATCTCACTTCAGCGG
TGGCTTTAATAGGCGATGAACAAAATGCGATGATGGCTAATTTTATGCGCCAAATGGGCCAAAGCGTGCCTGAAAGCAAG
AAAACTTTAGAATTAAACCCTAACCATGCGATTTTGCAAAAACTCTTAAAGTGCGAAGATAAAGAGCAGTTGAGCGCTTT
TATCTGGTTGCTTTATGATGGGGCGAAGCTTTTAGAAAAAGGGGCTTTGAAAGACGCTAAAAGCTTTAATGAGCGCCTAA
ATAGCGTGCTGTTGAAAGCGTTGTAA

Upstream 100 bases:

>100_bases
AATTAAACATTCTTTCATGTTCTTTTTTAAGCCATAGCATACTCCTTTTAAGCGCGCTTTTATTGTATAATCTTAAAAAT
TTTATTAAAGGAAAAGATCG

Downstream 100 bases:

>100_bases
GGGGGTAAAACCCTTTTTAGGGGTTTGAATAAAAATGCTTAAATCTTTCAAACACTAATAGAAAAAGGGGCTTTAAAAGA
CGCTAAAAGTTTTAATGAGC

Product: heat shock protein 90

Products: NA

Alternate protein names: Heat shock protein htpG; High temperature protein G [H]

Number of amino acids: Translated: 621; Mature: 620

Protein sequence:

>621_residues
MSNQEYTFQTEINQLLDLMIHSLYSNKEIFLRELISNASDALDKLNYLMLTDEKLKGLNITPSIHLSFDSQKKTLTIKDN
GIGMDKNDLIEHLGTIAKSGTKSFLSALSGDKKKDSALIGQFGVGFYSAFMVASKIVVQTKKVTNHQAYAWVSDGKGKFE
ISECVKEEQGTEITLFLKEEDSHFASRWEIDGIVKKYSEHIPFPIFLTYTDTKFEGEGDHKKEVKEEKCDQINQASALWK
MNKSELKDKDYKDFYQSFAHDNSEPLSYIHNKVEGSLEYTTLFYIPSKAPFDMFRVDYKSGVKLYVKRVFITDDDKELLP
SYLRFVKGVIDSEDLPLNVSREILQQNKILANIRSASVKKILSEIERLSKDEKNYHKFYEPFGKVLKEGLYGDFENKEKL
LELLRFYSKDKEKLISLKEYRENLKENQKSIYYLLGENLDLLKASPLLEKYAQKGYDVLLLSDEIDAFVMPGVNEYDKTP
FRDASHSESLKELGLEEINDEVKDQFKDLMKAFEENLKDEIKGVELSSHLTSAVALIGDEQNAMMANFMRQMGQSVPESK
KTLELNPNHAILQKLLKCEDKEQLSAFIWLLYDGAKLLEKGALKDAKSFNERLNSVLLKAL

Sequences:

>Translated_621_residues
MSNQEYTFQTEINQLLDLMIHSLYSNKEIFLRELISNASDALDKLNYLMLTDEKLKGLNITPSIHLSFDSQKKTLTIKDN
GIGMDKNDLIEHLGTIAKSGTKSFLSALSGDKKKDSALIGQFGVGFYSAFMVASKIVVQTKKVTNHQAYAWVSDGKGKFE
ISECVKEEQGTEITLFLKEEDSHFASRWEIDGIVKKYSEHIPFPIFLTYTDTKFEGEGDHKKEVKEEKCDQINQASALWK
MNKSELKDKDYKDFYQSFAHDNSEPLSYIHNKVEGSLEYTTLFYIPSKAPFDMFRVDYKSGVKLYVKRVFITDDDKELLP
SYLRFVKGVIDSEDLPLNVSREILQQNKILANIRSASVKKILSEIERLSKDEKNYHKFYEPFGKVLKEGLYGDFENKEKL
LELLRFYSKDKEKLISLKEYRENLKENQKSIYYLLGENLDLLKASPLLEKYAQKGYDVLLLSDEIDAFVMPGVNEYDKTP
FRDASHSESLKELGLEEINDEVKDQFKDLMKAFEENLKDEIKGVELSSHLTSAVALIGDEQNAMMANFMRQMGQSVPESK
KTLELNPNHAILQKLLKCEDKEQLSAFIWLLYDGAKLLEKGALKDAKSFNERLNSVLLKAL
>Mature_620_residues
SNQEYTFQTEINQLLDLMIHSLYSNKEIFLRELISNASDALDKLNYLMLTDEKLKGLNITPSIHLSFDSQKKTLTIKDNG
IGMDKNDLIEHLGTIAKSGTKSFLSALSGDKKKDSALIGQFGVGFYSAFMVASKIVVQTKKVTNHQAYAWVSDGKGKFEI
SECVKEEQGTEITLFLKEEDSHFASRWEIDGIVKKYSEHIPFPIFLTYTDTKFEGEGDHKKEVKEEKCDQINQASALWKM
NKSELKDKDYKDFYQSFAHDNSEPLSYIHNKVEGSLEYTTLFYIPSKAPFDMFRVDYKSGVKLYVKRVFITDDDKELLPS
YLRFVKGVIDSEDLPLNVSREILQQNKILANIRSASVKKILSEIERLSKDEKNYHKFYEPFGKVLKEGLYGDFENKEKLL
ELLRFYSKDKEKLISLKEYRENLKENQKSIYYLLGENLDLLKASPLLEKYAQKGYDVLLLSDEIDAFVMPGVNEYDKTPF
RDASHSESLKELGLEEINDEVKDQFKDLMKAFEENLKDEIKGVELSSHLTSAVALIGDEQNAMMANFMRQMGQSVPESKK
TLELNPNHAILQKLLKCEDKEQLSAFIWLLYDGAKLLEKGALKDAKSFNERLNSVLLKAL

Specific function: Molecular chaperone. Has ATPase activity [H]

COG id: COG0326

COG function: function code O; Molecular chaperone, HSP90 family

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the heat shock protein 90 family [H]

Homologues:

Organism=Homo sapiens, GI155722983, Length=644, Percent_Identity=32.6086956521739, Blast_Score=346, Evalue=4e-95,
Organism=Homo sapiens, GI154146191, Length=401, Percent_Identity=34.9127182044888, Blast_Score=234, Evalue=2e-61,
Organism=Homo sapiens, GI153792590, Length=401, Percent_Identity=34.9127182044888, Blast_Score=233, Evalue=5e-61,
Organism=Homo sapiens, GI20149594, Length=401, Percent_Identity=34.9127182044888, Blast_Score=232, Evalue=9e-61,
Organism=Homo sapiens, GI4507677, Length=210, Percent_Identity=46.6666666666667, Blast_Score=176, Evalue=4e-44,
Organism=Escherichia coli, GI1786679, Length=635, Percent_Identity=46.1417322834646, Blast_Score=546, Evalue=1e-156,
Organism=Caenorhabditis elegans, GI17559162, Length=656, Percent_Identity=37.8048780487805, Blast_Score=400, Evalue=1e-112,
Organism=Caenorhabditis elegans, GI17542208, Length=669, Percent_Identity=36.1733931240658, Blast_Score=379, Evalue=1e-105,
Organism=Caenorhabditis elegans, GI115535205, Length=645, Percent_Identity=32.5581395348837, Blast_Score=293, Evalue=2e-79,
Organism=Caenorhabditis elegans, GI115535167, Length=438, Percent_Identity=36.3013698630137, Blast_Score=254, Evalue=9e-68,
Organism=Saccharomyces cerevisiae, GI6323840, Length=685, Percent_Identity=36.9343065693431, Blast_Score=395, Evalue=1e-110,
Organism=Saccharomyces cerevisiae, GI6325016, Length=215, Percent_Identity=46.5116279069767, Blast_Score=178, Evalue=2e-45,
Organism=Drosophila melanogaster, GI17647529, Length=650, Percent_Identity=36.6153846153846, Blast_Score=380, Evalue=1e-105,
Organism=Drosophila melanogaster, GI21357739, Length=632, Percent_Identity=37.5, Blast_Score=369, Evalue=1e-102,
Organism=Drosophila melanogaster, GI24586016, Length=648, Percent_Identity=33.0246913580247, Blast_Score=321, Evalue=1e-87,

Paralogues:

None

Copy number: 640 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 2419 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR019805
- InterPro:   IPR001404
- InterPro:   IPR020575
- InterPro:   IPR020568 [H]

Pfam domain/function: PF02518 HATPase_c; PF00183 HSP90 [H]

EC number: NA

Molecular weight: Translated: 71334; Mature: 71203

Theoretical pI: Translated: 5.52; Mature: 5.52

Prosite motif: PS00298 HSP90

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNQEYTFQTEINQLLDLMIHSLYSNKEIFLRELISNASDALDKLNYLMLTDEKLKGLNI
CCCCCEEHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHEEEEECCCCCCCCC
TPSIHLSFDSQKKTLTIKDNGIGMDKNDLIEHLGTIAKSGTKSFLSALSGDKKKDSALIG
CCEEEEEECCCCCEEEEECCCCCCCHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCHHHHH
QFGVGFYSAFMVASKIVVQTKKVTNHQAYAWVSDGKGKFEISECVKEEQGTEITLFLKEE
HHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCHHHHHHHHCCCCEEEEEEECC
DSHFASRWEIDGIVKKYSEHIPFPIFLTYTDTKFEGEGDHKKEVKEEKCDQINQASALWK
CCHHHHHHHHHHHHHHHHHCCCCEEEEEEECCEECCCCCHHHHHHHHHHHHHHHHHHHHH
MNKSELKDKDYKDFYQSFAHDNSEPLSYIHNKVEGSLEYTTLFYIPSKAPFDMFRVDYKS
CCHHHCCCCHHHHHHHHHCCCCCCHHHHHHHHHCCCEEEEEEEEECCCCCHHHHHHHHHC
GVKLYVKRVFITDDDKELLPSYLRFVKGVIDSEDLPLNVSREILQQNKILANIRSASVKK
CCEEEEEEEEECCCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
ILSEIERLSKDEKNYHKFYEPFGKVLKEGLYGDFENKEKLLELLRFYSKDKEKLISLKEY
HHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHH
RENLKENQKSIYYLLGENLDLLKASPLLEKYAQKGYDVLLLSDEIDAFVMPGVNEYDKTP
HHHHHHCCCEEEEEECCCCCHHHCCHHHHHHHHCCCEEEEEECCCCEEECCCCCCCCCCC
FRDASHSESLKELGLEEINDEVKDQFKDLMKAFEENLKDEIKGVELSSHLTSAVALIGDE
CCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCC
QNAMMANFMRQMGQSVPESKKTLELNPNHAILQKLLKCEDKEQLSAFIWLLYDGAKLLEK
CHHHHHHHHHHHHCCCCCCCCEEEECCCHHHHHHHHCCCCHHHHHHHHHHHHCCHHHHHH
GALKDAKSFNERLNSVLLKAL
HCHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SNQEYTFQTEINQLLDLMIHSLYSNKEIFLRELISNASDALDKLNYLMLTDEKLKGLNI
CCCCEEHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHEEEEECCCCCCCCC
TPSIHLSFDSQKKTLTIKDNGIGMDKNDLIEHLGTIAKSGTKSFLSALSGDKKKDSALIG
CCEEEEEECCCCCEEEEECCCCCCCHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCHHHHH
QFGVGFYSAFMVASKIVVQTKKVTNHQAYAWVSDGKGKFEISECVKEEQGTEITLFLKEE
HHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCHHHHHHHHCCCCEEEEEEECC
DSHFASRWEIDGIVKKYSEHIPFPIFLTYTDTKFEGEGDHKKEVKEEKCDQINQASALWK
CCHHHHHHHHHHHHHHHHHCCCCEEEEEEECCEECCCCCHHHHHHHHHHHHHHHHHHHHH
MNKSELKDKDYKDFYQSFAHDNSEPLSYIHNKVEGSLEYTTLFYIPSKAPFDMFRVDYKS
CCHHHCCCCHHHHHHHHHCCCCCCHHHHHHHHHCCCEEEEEEEEECCCCCHHHHHHHHHC
GVKLYVKRVFITDDDKELLPSYLRFVKGVIDSEDLPLNVSREILQQNKILANIRSASVKK
CCEEEEEEEEECCCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
ILSEIERLSKDEKNYHKFYEPFGKVLKEGLYGDFENKEKLLELLRFYSKDKEKLISLKEY
HHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHH
RENLKENQKSIYYLLGENLDLLKASPLLEKYAQKGYDVLLLSDEIDAFVMPGVNEYDKTP
HHHHHHCCCEEEEEECCCCCHHHCCHHHHHHHHCCCEEEEEECCCCEEECCCCCCCCCCC
FRDASHSESLKELGLEEINDEVKDQFKDLMKAFEENLKDEIKGVELSSHLTSAVALIGDE
CCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCC
QNAMMANFMRQMGQSVPESKKTLELNPNHAILQKLLKCEDKEQLSAFIWLLYDGAKLLEK
CHHHHHHHHHHHHCCCCCCCCEEEECCCHHHHHHHHCCCCHHHHHHHHHHHHCCHHHHHH
GALKDAKSFNERLNSVLLKAL
HCHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA