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The map label for this gene is 108562600

Identifier: 108562600

GI number: 108562600

Start: 180487

End: 181509

Strand: Reverse

Name: 108562600

Synonym: HPAG1_0175

Alternate gene names: NA

Gene position: 181509-180487 (Counterclockwise)

Preceding gene: 108562601

Following gene: 108562595

Centisome position: 11.37

GC content: 39.59

Gene sequence:

>1023_bases
ATGTTGCAACGCCCTAAAATTGTCGCTGAATTGAGCGCTAATCATAACCAGGATTTAAACCTAGCCAAAGAAAGCCTTCA
TGCCATTAAGGAAAGCGGGGCGGATTTTGTCAAGCTCCAAACCTACACGCCAAGCTGCATGACTTTAAACTCTAAAGAAG
ATCCTTTCATCATTCAAGGCACTTTATGGGATAAAGAAAATTTGTATGAATTGTATCAAAAGGCTTCTACCCCCCTAGAG
TGGCATGCGGAATTGTTTGAGTTGGCTAGAAAGCTTGATTTAGGCATTTTTAGCTCGCCTTTTAGCTCAAAAGCCTTAGA
GCTTTTAGAGAGCCTAAATTGCCCCATGTATAAAATCGCTAGTTTTGAAATCGTTGATTTAGACTTGATTGAAAAGGCCG
CTCGCACACAAAAGCCCATTATCCTTTCTAGCGGTATCGCCACACACGACGAATTACAAGACGCTATTTCTTTGTGCAGA
GGAGTGAATAATTTTGACATCACCCTTTTAAAATGCGTGAGCGCTTATCCCAGTAAAATAGAAGATGCTAACCTATTAAG
CATGGTTAAATTAGGCGAAACCTTTGGCGTTAAATTTGGCTTAAGCGATCACACGATTGGTTCTCTTTGTCCCATTTTAG
CCACCACTTTAGGAGCGAGCATGATAGAAAAGCATTTCATTTTAAACAAATCCTTACAAACCCCAGACAGCGCTTTTAGC
ATGGATTTTAACGAATTTAAAAGCATGGTTGAAGCCATCAAACAAAGCGTTTTAGCCTTGGGCGAAAAAGAGCCTAAAAT
CAATCCAAAGACTTTAGAGGAGCGAAGATTCTTTATGCGCTCTTTATTTGTCATTAAGGATATTCAAAAAGGCGAAGCAT
TGACTAGCGATAATATCAAAGCCTTACGCCCCAACCTTGGCTTACACCCTAAATTTTATAAAGAAATTTTAAGCCAAAAG
GCATCAAAATTCTTAAAAGCCAACACCCCTTTAAACGCTGATGATATAGAACGCTCACTGTAG

Upstream 100 bases:

>100_bases
AGGGGCGTTAGTTTTAGCCACGCATGATGAGCATTTGGCTTTCACTTGCTCTCAAGTCTATCGCTTAGAAAAAGAAGTTT
TGATTAAGGAAAAATAAGAA

Downstream 100 bases:

>100_bases
GTTTGTTTTGATTAAAAAATTAGCGCTCGCTTTTTGGATATATCCTAAAGTAGAAGGATCTTTAACATTTCGTAAATAAG
CGTTAATAAGCTGGCGTGAG

Product: sialic acid synthase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 340; Mature: 340

Protein sequence:

>340_residues
MLQRPKIVAELSANHNQDLNLAKESLHAIKESGADFVKLQTYTPSCMTLNSKEDPFIIQGTLWDKENLYELYQKASTPLE
WHAELFELARKLDLGIFSSPFSSKALELLESLNCPMYKIASFEIVDLDLIEKAARTQKPIILSSGIATHDELQDAISLCR
GVNNFDITLLKCVSAYPSKIEDANLLSMVKLGETFGVKFGLSDHTIGSLCPILATTLGASMIEKHFILNKSLQTPDSAFS
MDFNEFKSMVEAIKQSVLALGEKEPKINPKTLEERRFFMRSLFVIKDIQKGEALTSDNIKALRPNLGLHPKFYKEILSQK
ASKFLKANTPLNADDIERSL

Sequences:

>Translated_340_residues
MLQRPKIVAELSANHNQDLNLAKESLHAIKESGADFVKLQTYTPSCMTLNSKEDPFIIQGTLWDKENLYELYQKASTPLE
WHAELFELARKLDLGIFSSPFSSKALELLESLNCPMYKIASFEIVDLDLIEKAARTQKPIILSSGIATHDELQDAISLCR
GVNNFDITLLKCVSAYPSKIEDANLLSMVKLGETFGVKFGLSDHTIGSLCPILATTLGASMIEKHFILNKSLQTPDSAFS
MDFNEFKSMVEAIKQSVLALGEKEPKINPKTLEERRFFMRSLFVIKDIQKGEALTSDNIKALRPNLGLHPKFYKEILSQK
ASKFLKANTPLNADDIERSL
>Mature_340_residues
MLQRPKIVAELSANHNQDLNLAKESLHAIKESGADFVKLQTYTPSCMTLNSKEDPFIIQGTLWDKENLYELYQKASTPLE
WHAELFELARKLDLGIFSSPFSSKALELLESLNCPMYKIASFEIVDLDLIEKAARTQKPIILSSGIATHDELQDAISLCR
GVNNFDITLLKCVSAYPSKIEDANLLSMVKLGETFGVKFGLSDHTIGSLCPILATTLGASMIEKHFILNKSLQTPDSAFS
MDFNEFKSMVEAIKQSVLALGEKEPKINPKTLEERRFFMRSLFVIKDIQKGEALTSDNIKALRPNLGLHPKFYKEILSQK
ASKFLKANTPLNADDIERSL

Specific function: Unknown

COG id: COG2089

COG function: function code M; Sialic acid synthase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: To B.subtilis spsE [H]

Homologues:

Organism=Homo sapiens, GI12056473, Length=299, Percent_Identity=29.7658862876254, Blast_Score=121, Evalue=1e-27,
Organism=Drosophila melanogaster, GI21357081, Length=252, Percent_Identity=28.968253968254, Blast_Score=104, Evalue=8e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006190
- InterPro:   IPR013785
- InterPro:   IPR013132
- InterPro:   IPR013974 [H]

Pfam domain/function: PF03102 NeuB; PF08666 SAF [H]

EC number: NA

Molecular weight: Translated: 38089; Mature: 38089

Theoretical pI: Translated: 6.41; Mature: 6.41

Prosite motif: PS50844 AFP_LIKE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLQRPKIVAELSANHNQDLNLAKESLHAIKESGADFVKLQTYTPSCMTLNSKEDPFIIQG
CCCCCCHHHHHCCCCCCCHHHHHHHHHHHHHCCCCEEEEEECCCCEEEECCCCCCEEEEE
TLWDKENLYELYQKASTPLEWHAELFELARKLDLGIFSSPFSSKALELLESLNCPMYKIA
ECCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCCEEEEC
SFEIVDLDLIEKAARTQKPIILSSGIATHDELQDAISLCRGVNNFDITLLKCVSAYPSKI
CEEEEHHHHHHHHHHCCCCEEEECCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCC
EDANLLSMVKLGETFGVKFGLSDHTIGSLCPILATTLGASMIEKHFILNKSLQTPDSAFS
CCCHHHHHHHHHHHHCEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHC
MDFNEFKSMVEAIKQSVLALGEKEPKINPKTLEERRFFMRSLFVIKDIQKGEALTSDNIK
CCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCH
ALRPNLGLHPKFYKEILSQKASKFLKANTPLNADDIERSL
HCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHCC
>Mature Secondary Structure
MLQRPKIVAELSANHNQDLNLAKESLHAIKESGADFVKLQTYTPSCMTLNSKEDPFIIQG
CCCCCCHHHHHCCCCCCCHHHHHHHHHHHHHCCCCEEEEEECCCCEEEECCCCCCEEEEE
TLWDKENLYELYQKASTPLEWHAELFELARKLDLGIFSSPFSSKALELLESLNCPMYKIA
ECCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCCEEEEC
SFEIVDLDLIEKAARTQKPIILSSGIATHDELQDAISLCRGVNNFDITLLKCVSAYPSKI
CEEEEHHHHHHHHHHCCCCEEEECCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCC
EDANLLSMVKLGETFGVKFGLSDHTIGSLCPILATTLGASMIEKHFILNKSLQTPDSAFS
CCCHHHHHHHHHHHHCEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHC
MDFNEFKSMVEAIKQSVLALGEKEPKINPKTLEERRFFMRSLFVIKDIQKGEALTSDNIK
CCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCH
ALRPNLGLHPKFYKEILSQKASKFLKANTPLNADDIERSL
HCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]