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The map label for this gene is yukB [H]

Identifier: 108562492

GI number: 108562492

Start: 67751

End: 69562

Strand: Direct

Name: yukB [H]

Synonym: HPAG1_0067

Alternate gene names: 108562492

Gene position: 67751-69562 (Clockwise)

Preceding gene: 108562491

Following gene: 108562502

Centisome position: 4.24

GC content: 41.45

Gene sequence:

>1812_bases
GTGGATGCTTTAAGTCAAAACGCGCTTTATTATCTGGAAAAAATCATGCGTTTTGGCTCTAAAAATGGGGTTTTGAGCTT
TGTCAATTTGGAGAGCGAAAAAAACAATAAATCCGCAGAAGATTTGAAACGCTATGCGGAGTGTTTTAAAGACAGGACAA
GTTTTGAACGCTTAAAATATCTTAGCGTAGAAGTGATCAATGATCATGGTATCCAATCTCAGCACATGCAAGACTTCGCT
GATAAAATTAAAGCGTATTACAAGCAAAAAAAAGAAGTTAAAAGGGAATTGAAAGACTTACAAAGAGATAAAGAATTTTG
GACTGAAAGCTCTCATTTTAAAGTGTCTGTGCCGGTGGGGTGGGATATTAACCACAAAGAGGTGTGTTTTGAGATCGGTG
AAGTGCAAAACCACACGTTCATTTGCGGGTGCAGCGGGAGCGGGAAATCCAATTTTTTGCATGTGTTGATCCAAGATTTA
GCTTTCTACTACGCGCCCAATGAGGTCCAACTCTTTTTGTTAGACTACAAAGAGGGGGTGGAATTTAACGCATACACAGA
TCCGAATATTTTAGAGCATGCGAGGCTGGTGAGCGTGGCGAGTTCGGTAGGTTATGGCATGAGTTTTTTAAGCTGGCTTT
GTAAAGAAATGCAAGAAAGAGCCAATCTGTTCAAGCAGTTTAATGTGAAAGATTTGAGCGATTACCGAAAGCATGGCGAA
ATGCCTAGACTGATCGTGGTGATTGATGAATTTCAGGTGCTTTTTAGCGACAACTCCTCTAAAGGGAAAGAGAGCGTGGA
GCAGTCTTTAAACACCCTGCTTAAAAAGGGCCGCAGCTATGGGGTGCATTTAATTTTAGCCACTCAAACCATGCGCGGCA
CTGACATCAATAGAAGCATTATGGCTCAAATTGCTAACTGCATCGCTTTGCCTATGGATGCAGACGACAGCGCTAAAATT
TTGGACGATGATGTAGCTTGTGAGCTTGTCAGGCCAGAAGGCATTTTCAACAACAACGGAGAGCATCAAAAATACCACAC
CAAGATGAGTATCCCTAAAGCCCCTGATGATTTCAAATCTTTTCTCACAAAAATACACGCTGAATTTAACCAAAGAAATC
TCGCGCCCATAGAGCGTAAAATCTATAATGGCGAGACACCTTTAAAAATGCCCAATATCCTTAAGGCTAATGAAATGCGT
TTGCATCTGGGCAAAAAAGTGGATTATGAGCAAAAGGACTTGATAGTGGAGCTTGAAAGTAACGAATCGCATTTGTTGGT
GGTGAGCCAAGATTTAAACGCTCGCATCGCTCTGATGAAGCTTTTCGCTCAAAATTTCAAGACTGCCAACAAAGAGTTGC
TCTTCTACAACGCCGAAAAACGCCTTGTGAGGGAACTTGATGGGTTGAAAAAACACCACATCACGCCCATGCAAGGCCCT
CTAGGGAGCGTTTTAGACACCGCTATGAACCCTAATAGCGTGCTGATAATAGACAATTTAAACGAAGCCAAAGAGTTGCA
CGACAAAATAGGGGTGGAAAAATTAAGATCGTTTTTAGAAAAAGCCACAGACAACGAGCAGTATTACATCATCTTTGCGC
ATGATTTCAAACAAATTCAAGCTAATTACGATTCTGTCAAGTTAAAAGAATTGTTAAACAACCACTTCAAACAACGCCTG
GCCTTTAAGTGTAATGGTGAGAACTTGAGCGCTCTTAAAAGCGAACAAAAGCTACACGAACTCAACGCACGCCTGATAAA
CACTTCTAAAGACAGCCGCACTGAGTTTAGGCCCTTCAGCTTACAAGATTAA

Upstream 100 bases:

>100_bases
AGGTTAATTTGCAAGAAAAATTGGCCGGTTATAAAGATTTTGCGCATTATAATGAAAACGCCACAGACCCCTTGCCTTTA
AAAGCGCTTTTTTAAGCGGG

Downstream 100 bases:

>100_bases
AAAAAGGGGGGGGGTTAAAAAAAGAGAGTTAAAAAAAAGAGAGTTAAAAAAAAGAGAGTTAAAAAAAAGAGAGTTAAAAA
AAAGAGAGTTAAAAAAAGGG

Product: ATP-binding protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 603; Mature: 603

Protein sequence:

>603_residues
MDALSQNALYYLEKIMRFGSKNGVLSFVNLESEKNNKSAEDLKRYAECFKDRTSFERLKYLSVEVINDHGIQSQHMQDFA
DKIKAYYKQKKEVKRELKDLQRDKEFWTESSHFKVSVPVGWDINHKEVCFEIGEVQNHTFICGCSGSGKSNFLHVLIQDL
AFYYAPNEVQLFLLDYKEGVEFNAYTDPNILEHARLVSVASSVGYGMSFLSWLCKEMQERANLFKQFNVKDLSDYRKHGE
MPRLIVVIDEFQVLFSDNSSKGKESVEQSLNTLLKKGRSYGVHLILATQTMRGTDINRSIMAQIANCIALPMDADDSAKI
LDDDVACELVRPEGIFNNNGEHQKYHTKMSIPKAPDDFKSFLTKIHAEFNQRNLAPIERKIYNGETPLKMPNILKANEMR
LHLGKKVDYEQKDLIVELESNESHLLVVSQDLNARIALMKLFAQNFKTANKELLFYNAEKRLVRELDGLKKHHITPMQGP
LGSVLDTAMNPNSVLIIDNLNEAKELHDKIGVEKLRSFLEKATDNEQYYIIFAHDFKQIQANYDSVKLKELLNNHFKQRL
AFKCNGENLSALKSEQKLHELNARLINTSKDSRTEFRPFSLQD

Sequences:

>Translated_603_residues
MDALSQNALYYLEKIMRFGSKNGVLSFVNLESEKNNKSAEDLKRYAECFKDRTSFERLKYLSVEVINDHGIQSQHMQDFA
DKIKAYYKQKKEVKRELKDLQRDKEFWTESSHFKVSVPVGWDINHKEVCFEIGEVQNHTFICGCSGSGKSNFLHVLIQDL
AFYYAPNEVQLFLLDYKEGVEFNAYTDPNILEHARLVSVASSVGYGMSFLSWLCKEMQERANLFKQFNVKDLSDYRKHGE
MPRLIVVIDEFQVLFSDNSSKGKESVEQSLNTLLKKGRSYGVHLILATQTMRGTDINRSIMAQIANCIALPMDADDSAKI
LDDDVACELVRPEGIFNNNGEHQKYHTKMSIPKAPDDFKSFLTKIHAEFNQRNLAPIERKIYNGETPLKMPNILKANEMR
LHLGKKVDYEQKDLIVELESNESHLLVVSQDLNARIALMKLFAQNFKTANKELLFYNAEKRLVRELDGLKKHHITPMQGP
LGSVLDTAMNPNSVLIIDNLNEAKELHDKIGVEKLRSFLEKATDNEQYYIIFAHDFKQIQANYDSVKLKELLNNHFKQRL
AFKCNGENLSALKSEQKLHELNARLINTSKDSRTEFRPFSLQD
>Mature_603_residues
MDALSQNALYYLEKIMRFGSKNGVLSFVNLESEKNNKSAEDLKRYAECFKDRTSFERLKYLSVEVINDHGIQSQHMQDFA
DKIKAYYKQKKEVKRELKDLQRDKEFWTESSHFKVSVPVGWDINHKEVCFEIGEVQNHTFICGCSGSGKSNFLHVLIQDL
AFYYAPNEVQLFLLDYKEGVEFNAYTDPNILEHARLVSVASSVGYGMSFLSWLCKEMQERANLFKQFNVKDLSDYRKHGE
MPRLIVVIDEFQVLFSDNSSKGKESVEQSLNTLLKKGRSYGVHLILATQTMRGTDINRSIMAQIANCIALPMDADDSAKI
LDDDVACELVRPEGIFNNNGEHQKYHTKMSIPKAPDDFKSFLTKIHAEFNQRNLAPIERKIYNGETPLKMPNILKANEMR
LHLGKKVDYEQKDLIVELESNESHLLVVSQDLNARIALMKLFAQNFKTANKELLFYNAEKRLVRELDGLKKHHITPMQGP
LGSVLDTAMNPNSVLIIDNLNEAKELHDKIGVEKLRSFLEKATDNEQYYIIFAHDFKQIQANYDSVKLKELLNNHFKQRL
AFKCNGENLSALKSEQKLHELNARLINTSKDSRTEFRPFSLQD

Specific function: DNA Motor Protein, Which Is Both Required To Move DNA Out Of The Region Of The Septum During Cell Division And For The Septum Formation. Tracks DNA In An ATP-Dependent Manner By Generating Positive Supercoils In Front Of It And Negative Supercoils Behind

COG id: COG1674

COG function: function code D; DNA segregation ATPase FtsK/SpoIIIE and related proteins

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 FtsK domains [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002543
- InterPro:   IPR022206 [H]

Pfam domain/function: PF01580 FtsK_SpoIIIE; PF12538 FtsK_SpoIIIE_N [H]

EC number: NA

Molecular weight: Translated: 69524; Mature: 69524

Theoretical pI: Translated: 7.19; Mature: 7.19

Prosite motif: PS50901 FTSK

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDALSQNALYYLEKIMRFGSKNGVLSFVNLESEKNNKSAEDLKRYAECFKDRTSFERLKY
CCCCHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
LSVEVINDHGIQSQHMQDFADKIKAYYKQKKEVKRELKDLQRDKEFWTESSHFKVSVPVG
HEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCC
WDINHKEVCFEIGEVQNHTFICGCSGSGKSNFLHVLIQDLAFYYAPNEVQLFLLDYKEGV
CCCCHHHHHHHHHCCCCCEEEEECCCCCCHHHHHHHHHHHHHHCCCCCEEEEEEECCCCC
EFNAYTDPNILEHARLVSVASSVGYGMSFLSWLCKEMQERANLFKQFNVKDLSDYRKHGE
EECCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCC
MPRLIVVIDEFQVLFSDNSSKGKESVEQSLNTLLKKGRSYGVHLILATQTMRGTDINRSI
CCEEEEEEECEEEEECCCCCCHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCCCCHHH
MAQIANCIALPMDADDSAKILDDDVACELVRPEGIFNNNGEHQKYHTKMSIPKAPDDFKS
HHHHHHHHCCCCCCCCCCCCCCCCHHEEEECCCCCCCCCCCCCEEEEECCCCCCCHHHHH
FLTKIHAEFNQRNLAPIERKIYNGETPLKMPNILKANEMRLHLGKKVDYEQKDLIVELES
HHHHHHHHHCCCCCCHHHHHHCCCCCCCCCCCCCCCCCHHEECCCCCCCCCCCEEEEEEC
NESHLLVVSQDLNARIALMKLFAQNFKTANKELLFYNAEKRLVRELDGLKKHHITPMQGP
CCCEEEEEECCCCHHHHHHHHHHHHHCCCCCEEEEECHHHHHHHHHHHHHHHCCCCCCCC
LGSVLDTAMNPNSVLIIDNLNEAKELHDKIGVEKLRSFLEKATDNEQYYIIFAHDFKQIQ
HHHHHHHCCCCCCEEEEECCHHHHHHHHHHCHHHHHHHHHHCCCCCEEEEEEECCHHHHH
ANYDSVKLKELLNNHFKQRLAFKCNGENLSALKSEQKLHELNARLINTSKDSRTEFRPFS
CCCCHHHHHHHHHHHHHHHHEEEECCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCC
LQD
CCC
>Mature Secondary Structure
MDALSQNALYYLEKIMRFGSKNGVLSFVNLESEKNNKSAEDLKRYAECFKDRTSFERLKY
CCCCHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
LSVEVINDHGIQSQHMQDFADKIKAYYKQKKEVKRELKDLQRDKEFWTESSHFKVSVPVG
HEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCC
WDINHKEVCFEIGEVQNHTFICGCSGSGKSNFLHVLIQDLAFYYAPNEVQLFLLDYKEGV
CCCCHHHHHHHHHCCCCCEEEEECCCCCCHHHHHHHHHHHHHHCCCCCEEEEEEECCCCC
EFNAYTDPNILEHARLVSVASSVGYGMSFLSWLCKEMQERANLFKQFNVKDLSDYRKHGE
EECCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCC
MPRLIVVIDEFQVLFSDNSSKGKESVEQSLNTLLKKGRSYGVHLILATQTMRGTDINRSI
CCEEEEEEECEEEEECCCCCCHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCCCCHHH
MAQIANCIALPMDADDSAKILDDDVACELVRPEGIFNNNGEHQKYHTKMSIPKAPDDFKS
HHHHHHHHCCCCCCCCCCCCCCCCHHEEEECCCCCCCCCCCCCEEEEECCCCCCCHHHHH
FLTKIHAEFNQRNLAPIERKIYNGETPLKMPNILKANEMRLHLGKKVDYEQKDLIVELES
HHHHHHHHHCCCCCCHHHHHHCCCCCCCCCCCCCCCCCHHEECCCCCCCCCCCEEEEEEC
NESHLLVVSQDLNARIALMKLFAQNFKTANKELLFYNAEKRLVRELDGLKKHHITPMQGP
CCCEEEEEECCCCHHHHHHHHHHHHHCCCCCEEEEECHHHHHHHHHHHHHHHCCCCCCCC
LGSVLDTAMNPNSVLIIDNLNEAKELHDKIGVEKLRSFLEKATDNEQYYIIFAHDFKQIQ
HHHHHHHCCCCCCEEEEECCHHHHHHHHHHCHHHHHHHHHHCCCCCEEEEEEECCHHHHH
ANYDSVKLKELLNNHFKQRLAFKCNGENLSALKSEQKLHELNARLINTSKDSRTEFRPFS
CCCCHHHHHHHHHHHHHHHHEEEECCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCC
LQD
CCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377; 9168598 [H]