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The map label for this gene is apaH [H]

Identifier: 107021946

GI number: 107021946

Start: 427722

End: 428561

Strand: Reverse

Name: apaH [H]

Synonym: Bcen_0388

Alternate gene names: 107021946

Gene position: 428561-427722 (Counterclockwise)

Preceding gene: 107021967

Following gene: 107021937

Centisome position: 13.01

GC content: 69.64

Gene sequence:

>840_bases
ATGACTTCCCCCCCCATCGCCATCGGCGACATCCAAGGCTGTCACATCGCTTTCCAGGCGCTGTACGAAAAGCTTTCGCC
CCCCACCGACACGCCCGTCTGGATCGCCGGCGACGTCGTCAACCGCGGCCCCGGCTCCCTCGCCGCGCTGCGCGCGGTCG
TCGATCTCGGCCCGCGCGCGACCGTCGTGCTCGGCAATCACGACCTCCACCTGCTCGCGGTCTCCGCCGGGCTGCGCACC
GAGCGCCCGGGCGACACGATCGGCGAGATCCTCGACGCGCCCGACGCCGACGCGCTGCTCGACTGGGTCCGCCATCGCCC
GTTCGTGCATGTCGAAGACGGAAAGTTGCTCGTACACGCCGGCGTGTTGCCGCAATGGGACGCCACGCTCGCGCTCGAAC
TCGCGGACGAGCTCCAGCGCGCGCTGCGTGCCCCCGATTGGCGCGACACGCTGCAAGGCCTGTACGGCAACGAGCCGAAT
CAATGGACGCCGAACCTGAAAAAACGCGACCGGATGCGCGTCGCATTCAACGCGTTCACGCGCCTGCGCTTCTGCACGCC
CGACGGCGCGATGGAATTCAAGGCGAACGGCGGCCCCGACAGCGCGCCGCCCGGCTACCTGCCGTGGTTCGACGTGCCGG
GGCGCCGCACCGAGGACGTGACGGTCGTGTTCGGGCACTGGGCCGCGCTCGGCCTGATGTTGCGCGACAACCTCGTCGCG
CTCGATTCAGGCTGCGTATGGGGAAATCAGTTGTCGGCCGTGCGGCTCACGGCCGATCCGGCGCAGCGCACGGTCACGCA
GGTGCAGTGCGAAGCGTGCCGTTCGCCGGGCGGCGAATGA

Upstream 100 bases:

>100_bases
TTGCCAAATCAACGCACGGTTGCGGAACACAAATTGCGCAACACTGCAGTGACTGGATAATTTTTCCCGTGTTCTCGATA
CTCGCGAAATCCCCTGCCCC

Downstream 100 bases:

>100_bases
CGGCACACTGATTCGCCCGCCCCGGCCGGCCGCGCATCAGCCCTCGCGCCCCGGCACCGGCGCATCGGCTGCCGCGTCGC
CCGTCGCACCGGCGCCGAGC

Product: diadenosine tetraphosphatase

Products: NA

Alternate protein names: Ap4A hydrolase; Diadenosine 5',5'''-P1,P4-tetraphosphate pyrophosphohydrolase; Diadenosine tetraphosphatase [H]

Number of amino acids: Translated: 279; Mature: 278

Protein sequence:

>279_residues
MTSPPIAIGDIQGCHIAFQALYEKLSPPTDTPVWIAGDVVNRGPGSLAALRAVVDLGPRATVVLGNHDLHLLAVSAGLRT
ERPGDTIGEILDAPDADALLDWVRHRPFVHVEDGKLLVHAGVLPQWDATLALELADELQRALRAPDWRDTLQGLYGNEPN
QWTPNLKKRDRMRVAFNAFTRLRFCTPDGAMEFKANGGPDSAPPGYLPWFDVPGRRTEDVTVVFGHWAALGLMLRDNLVA
LDSGCVWGNQLSAVRLTADPAQRTVTQVQCEACRSPGGE

Sequences:

>Translated_279_residues
MTSPPIAIGDIQGCHIAFQALYEKLSPPTDTPVWIAGDVVNRGPGSLAALRAVVDLGPRATVVLGNHDLHLLAVSAGLRT
ERPGDTIGEILDAPDADALLDWVRHRPFVHVEDGKLLVHAGVLPQWDATLALELADELQRALRAPDWRDTLQGLYGNEPN
QWTPNLKKRDRMRVAFNAFTRLRFCTPDGAMEFKANGGPDSAPPGYLPWFDVPGRRTEDVTVVFGHWAALGLMLRDNLVA
LDSGCVWGNQLSAVRLTADPAQRTVTQVQCEACRSPGGE
>Mature_278_residues
TSPPIAIGDIQGCHIAFQALYEKLSPPTDTPVWIAGDVVNRGPGSLAALRAVVDLGPRATVVLGNHDLHLLAVSAGLRTE
RPGDTIGEILDAPDADALLDWVRHRPFVHVEDGKLLVHAGVLPQWDATLALELADELQRALRAPDWRDTLQGLYGNEPNQ
WTPNLKKRDRMRVAFNAFTRLRFCTPDGAMEFKANGGPDSAPPGYLPWFDVPGRRTEDVTVVFGHWAALGLMLRDNLVAL
DSGCVWGNQLSAVRLTADPAQRTVTQVQCEACRSPGGE

Specific function: Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP [H]

COG id: COG0639

COG function: function code T; Diadenosine tetraphosphatase and related serine/threonine protein phosphatases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Ap4A hydrolase family [H]

Homologues:

Organism=Escherichia coli, GI1786234, Length=253, Percent_Identity=44.2687747035573, Blast_Score=223, Evalue=1e-59,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004617
- InterPro:   IPR004843 [H]

Pfam domain/function: PF00149 Metallophos [H]

EC number: =3.6.1.41 [H]

Molecular weight: Translated: 30359; Mature: 30228

Theoretical pI: Translated: 5.33; Mature: 5.33

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSPPIAIGDIQGCHIAFQALYEKLSPPTDTPVWIAGDVVNRGPGSLAALRAVVDLGPRA
CCCCCEEEECCCHHHHHHHHHHHHHCCCCCCCEEEECCCCCCCCCHHHHHHHHHHCCCCE
TVVLGNHDLHLLAVSAGLRTERPGDTIGEILDAPDADALLDWVRHRPFVHVEDGKLLVHA
EEEECCCCEEEEEEECCCCCCCCCCHHHHHHCCCCHHHHHHHHHCCCEEEEECCEEEEEE
GVLPQWDATLALELADELQRALRAPDWRDTLQGLYGNEPNQWTPNLKKRDRMRVAFNAFT
CCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCCCHHHHHHHHHHEEHHH
RLRFCTPDGAMEFKANGGPDSAPPGYLPWFDVPGRRTEDVTVVFGHWAALGLMLRDNLVA
EEEEECCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCCEEEEEECHHHHHHHHHCCEEE
LDSGCVWGNQLSAVRLTADPAQRTVTQVQCEACRSPGGE
EECCCEECCCCCEEEEECCHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure 
TSPPIAIGDIQGCHIAFQALYEKLSPPTDTPVWIAGDVVNRGPGSLAALRAVVDLGPRA
CCCCEEEECCCHHHHHHHHHHHHHCCCCCCCEEEECCCCCCCCCHHHHHHHHHHCCCCE
TVVLGNHDLHLLAVSAGLRTERPGDTIGEILDAPDADALLDWVRHRPFVHVEDGKLLVHA
EEEECCCCEEEEEEECCCCCCCCCCHHHHHHCCCCHHHHHHHHHCCCEEEEECCEEEEEE
GVLPQWDATLALELADELQRALRAPDWRDTLQGLYGNEPNQWTPNLKKRDRMRVAFNAFT
CCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCCCHHHHHHHHHHEEHHH
RLRFCTPDGAMEFKANGGPDSAPPGYLPWFDVPGRRTEDVTVVFGHWAALGLMLRDNLVA
EEEEECCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCCEEEEEECHHHHHHHHHCCEEE
LDSGCVWGNQLSAVRLTADPAQRTVTQVQCEACRSPGGE
EECCCEECCCCCEEEEECCHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA