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The map label for this gene is exuR [H]

Identifier: 107021722

GI number: 107021722

Start: 169435

End: 170310

Strand: Reverse

Name: exuR [H]

Synonym: Bcen_0162

Alternate gene names: 107021722

Gene position: 170310-169435 (Counterclockwise)

Preceding gene: 107021726

Following gene: 107021720

Centisome position: 5.17

GC content: 66.32

Gene sequence:

>876_bases
ATGTTATGGTGGATAGTAGGAAGCCGATATAGTGGCGTCAAGGACGGACAAAATAGGGATTTCCCGCCCCTGCGCGCCGT
TTGCGCGCCCCGCAAAGGGGCGGATCGTGGCTTTCCCGTAGGGTGGTCATGCACCGCCCGCGTGCGGATTACAATGCCGG
TCAGACCGGCCATCGTTCACATCATGAAAAATGTTCCGCATACCGTGACCGACGCCGCCATCGCGACGATCCGCGACCGG
ATCGAGGCAGGCGTCTATCCGGTCGGCAGCCTGCTGCCGGCCCAGCGCCAGCTCTCCGAGGAGCTGGAGATCAGCCGCGC
GTCGCTGCGCGAGGCGCTGTCGACGCTCGAGGCGCTCGGGATGCTGCGCATCCGCGCGGGCAAGGGCGTGTACGTCGAAA
GCGCGCAGGCGTCCGCCGCGCATCCGTGGCAATTCGCCGAGCAGTCGTCCCCGCCCGATACGTACCAGATGCGCTATGCG
CTCGAAGGCTTCGCCGCGCGGATGGCCGCGCACGTCGTCAGCGACGAAGACATCGCGTGGTTCGAGGACAATCTCGCCGA
CCTGCACGTCGCGCTGACCGAAAGCGCGCTCGACGAAGCATCGCGGCTCGACTTCGACTTCCACATGCGGATCATTCATC
TGGCCGGCAACGCGGCGATCGAATCCATCCTGCGCAGCAGCGCGGACATCATGAAGGAAAGCCAGCGCATGCCGTTCTAC
CGGCGCGAGCTGCTGCTGTCGACGTGGCACGAGCACCGCGCGATCGTCGACGCGCTGATCGCGCGCGATGCGGCAGCCGC
CGGCACCGCGATCGAAACGCACATCACGAACGCGGCGCAGCGCGCGGGCGTCTTCTTCCCGACGCCCGGCGCGTAA

Upstream 100 bases:

>100_bases
CGACGACTACCCGGCCAAACAGCGAATTGAGGAATTTCGACACGGCGCTCTCCCGTTCCAACGGTTGCAGTTTCGTCTGT
TCATACTGGTAAGACCAGTG

Downstream 100 bases:

>100_bases
TCCTCCCGCGCCGCGGCCCGGCCTTCCGCCCGGCCGTGCCGGTCACCGTTCCGACGGATCGCGATATGCGAGCACGCGCT
CGATGAATGCGCGCGCCGCG

Product: GntR-like

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 291; Mature: 291

Protein sequence:

>291_residues
MLWWIVGSRYSGVKDGQNRDFPPLRAVCAPRKGADRGFPVGWSCTARVRITMPVRPAIVHIMKNVPHTVTDAAIATIRDR
IEAGVYPVGSLLPAQRQLSEELEISRASLREALSTLEALGMLRIRAGKGVYVESAQASAAHPWQFAEQSSPPDTYQMRYA
LEGFAARMAAHVVSDEDIAWFEDNLADLHVALTESALDEASRLDFDFHMRIIHLAGNAAIESILRSSADIMKESQRMPFY
RRELLLSTWHEHRAIVDALIARDAAAAGTAIETHITNAAQRAGVFFPTPGA

Sequences:

>Translated_291_residues
MLWWIVGSRYSGVKDGQNRDFPPLRAVCAPRKGADRGFPVGWSCTARVRITMPVRPAIVHIMKNVPHTVTDAAIATIRDR
IEAGVYPVGSLLPAQRQLSEELEISRASLREALSTLEALGMLRIRAGKGVYVESAQASAAHPWQFAEQSSPPDTYQMRYA
LEGFAARMAAHVVSDEDIAWFEDNLADLHVALTESALDEASRLDFDFHMRIIHLAGNAAIESILRSSADIMKESQRMPFY
RRELLLSTWHEHRAIVDALIARDAAAAGTAIETHITNAAQRAGVFFPTPGA
>Mature_291_residues
MLWWIVGSRYSGVKDGQNRDFPPLRAVCAPRKGADRGFPVGWSCTARVRITMPVRPAIVHIMKNVPHTVTDAAIATIRDR
IEAGVYPVGSLLPAQRQLSEELEISRASLREALSTLEALGMLRIRAGKGVYVESAQASAAHPWQFAEQSSPPDTYQMRYA
LEGFAARMAAHVVSDEDIAWFEDNLADLHVALTESALDEASRLDFDFHMRIIHLAGNAAIESILRSSADIMKESQRMPFY
RRELLLSTWHEHRAIVDALIARDAAAAGTAIETHITNAAQRAGVFFPTPGA

Specific function: Repressor for the exu regulon that encode genes involved in hexuronate utilization. It regulates the exuT, uxaCA and uxuRAB operons. Binds D-tagaturonate and D-fructuronate as inducers [H]

COG id: COG2186

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH gntR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790780, Length=224, Percent_Identity=30.8035714285714, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI87082208, Length=227, Percent_Identity=29.0748898678414, Blast_Score=83, Evalue=3e-17,
Organism=Escherichia coli, GI1786303, Length=203, Percent_Identity=30.0492610837438, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1790032, Length=224, Percent_Identity=27.2321428571429, Blast_Score=69, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011711
- InterPro:   IPR000524
- InterPro:   IPR011991 [H]

Pfam domain/function: PF07729 FCD; PF00392 GntR [H]

EC number: NA

Molecular weight: Translated: 32097; Mature: 32097

Theoretical pI: Translated: 6.86; Mature: 6.86

Prosite motif: PS50949 HTH_GNTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLWWIVGSRYSGVKDGQNRDFPPLRAVCAPRKGADRGFPVGWSCTARVRITMPVRPAIVH
CEEEEECCCCCCCCCCCCCCCCHHHHHHCCCCCCCCCCCCCCCEEEEEEEEECCHHHHHH
IMKNVPHTVTDAAIATIRDRIEAGVYPVGSLLPAQRQLSEELEISRASLREALSTLEALG
HHHHCCCHHHHHHHHHHHHHHHCCCCCHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MLRIRAGKGVYVESAQASAAHPWQFAEQSSPPDTYQMRYALEGFAARMAAHVVSDEDIAW
HHEEECCCCEEEECCCCCCCCCCHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCHH
FEDNLADLHVALTESALDEASRLDFDFHMRIIHLAGNAAIESILRSSADIMKESQRMPFY
HHCCHHHHHHHHHHHHHHHHHHCCHHHEEEEEEECCHHHHHHHHHHHHHHHHHHHCCCHH
RRELLLSTWHEHRAIVDALIARDAAAAGTAIETHITNAAQRAGVFFPTPGA
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure
MLWWIVGSRYSGVKDGQNRDFPPLRAVCAPRKGADRGFPVGWSCTARVRITMPVRPAIVH
CEEEEECCCCCCCCCCCCCCCCHHHHHHCCCCCCCCCCCCCCCEEEEEEEEECCHHHHHH
IMKNVPHTVTDAAIATIRDRIEAGVYPVGSLLPAQRQLSEELEISRASLREALSTLEALG
HHHHCCCHHHHHHHHHHHHHHHCCCCCHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MLRIRAGKGVYVESAQASAAHPWQFAEQSSPPDTYQMRYALEGFAARMAAHVVSDEDIAW
HHEEECCCCEEEECCCCCCCCCCHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCHH
FEDNLADLHVALTESALDEASRLDFDFHMRIIHLAGNAAIESILRSSADIMKESQRMPFY
HHCCHHHHHHHHHHHHHHHHHHCCHHHEEEEEEECCHHHHHHHHHHHHHHHHHHHCCCHH
RRELLLSTWHEHRAIVDALIARDAAAAGTAIETHITNAAQRAGVFFPTPGA
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA