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The map label for this gene is lgrD [H]

Identifier: 104779428

GI number: 104779428

Start: 121613

End: 125044

Strand: Reverse

Name: lgrD [H]

Synonym: PSEEN0132

Alternate gene names: 104779428

Gene position: 125044-121613 (Counterclockwise)

Preceding gene: 104779429

Following gene: 104779427

Centisome position: 2.12

GC content: 65.73

Gene sequence:

>3432_bases
ATGAGACGCCTCGACATACTCCTGGTGGGCAACAGCCCCGCCCTGGGGCAGCTTGCCCATCAGCTCGGCGAACATGGCCA
TGGCATCACCATCGCCGACAACGCCGAAACCTTGCGCCAGCAACTGGTTGTTCGCCCGCACCTGGTGGTGGAGGACGGCA
GCCTGGCGCTGAACAGCAGCGACTGGCAATCATTGGACGCTACGCCCTTGCTCAGGCTGCGCCTGGGCGCCAGCTTCGCC
GAAACCCTGCCACGCCTCGAGACCCTGTGCTGGTGCGGCAGTGCCAGCGCCCAACGGCTGATCGAACGCCTGCCCGTGCC
GTCGCCTGCCTCCGGCAACGGCCAGCAGCTGCGTGAGGACGCCCTGCAAGCCCTGAACGACCTGCTCGCCCTGCAGGTCA
CCCGCTATGCCCGCAACCCGCAGTACCTGCAGGAGGCTCCCGCCGTCAGCCCCGGCGTGCAGGAGCGCGAACATGGCCTG
GACTGGCTGGAGGCGCTGGCCTACCGGCACCCGTTCAACCGCACGCTGCGCGCCGACCTCCTGGAACAGGCCGAGACCGG
CTTGATCGGGCAACTGGAGCACAGCCTGCGCCAACACGCCGAACGCACAGCGTTGAACCGCGACGGCCAGCGCTACAGCT
ATGGGCAGCTGCATGCCCGCACCGTCGCGATCCAGCGTGTGCTGCTGCCGCTGTTGCCAGAAGCGGGCGAGCACCCTCCG
GTGGTCGCCGTGTGCATGGCCAAGTCACCCGAGCTCTATGCCAGCTTGCTGGCGATCCTGGGCTGTTCGGCCATTTACCT
ACCCCTGGACCCGGCGACCCCGGCCGAACGCCGTCAACGCATCCTGGCCGACGCCAAAGCCTGTGTAGTACTACATGACG
GCCAGGAGCCCGTGGGTATCGCGCACCTGGATGTCCGTGCGCTGTCGATCGCCGAGGACGCCCAACTGCCCTCCCTGGCA
CAACGCCCGGCCTGCGCCGGCCAGGCCTGCGTGGCGATCTACACCTCCGGTACCACGGGCCTGCCCAAGGGTGTGTTGCT
CAGCCAGGGCAACCTGGCGCACTTCATGGCCTGGTACCGCGAGCACGTGGCACTGGACCGGCACAGCCGGGTGTTGCAGT
TCTCCACCATCGGCTTCGACGCTTCCCTGCTGGATATCCTGCCCACCTTCGCCTGCGGTGCCGAACTGGTGCTACCCAAC
GAAGACCAGCGCCGTGACCCGCAACAGCTGGTGCGACTTATCCACAGCCAGGCCGTCACCCACGCATTTCTGCCGCCGGC
CCTGTTGAGCATCCTGTCGCGTGATACACACCTGGGCTTGAAGCATCTGGTCACTGGCGGCGATGTCTGCGAACCGGAAG
TCATCGTCCGGCTGTCCGGGCAATGCCGGATGCACAACATCTATGGCCCGACCGAAACCACCGTGCTGGCAACTACCCGG
GTGTTCGCCAGCGGCGAAAGCAACCGCAACCTCGGCCTGCCCATCGCCAACACCCAGGTTTTGATCCTCGACGAAGACCT
GCGGCCGGTCACGCAGCAGGTTGCGGGTGAGCTTTACATCACCGGCCCTGGCGTCGGGCTCGGCTACCTGAACAACCCGG
CCCTGACCGCCGAACGCTTCGTCGAGCTGTGCCTGCCCGATGGCCGTGCATTGCGTGCCTATCGCACGGGTGATATCGGC
AAGTGGACCACCCAAGGCATCGAGTTGTCCGGCCGCCGTGACAACCAGGTAAAGATCCGCGGCTTTCGCGTTGAGCCGGA
AGAGATCGAACACTGCCTGCGCGACAGCCAGCTGTTCGCCCAGGTGGCGGTGGTGATTGACGCCCAGCGCCGCGTGCTTG
CGTTCGTCGCCCATGGCCACGGCGCAGATGCCGAACAGCAACTGCGCGCGCACGCCGAGCAGCACCTGCCCGACTACATG
CGCCCGATGATCTACCAGGTGCTGGAGCAGATGCCCTACACCGCCAATGGCAAGGTGGATCGCCAGGCGCTGTCGCAGCG
ACCACTGGCCCTGCCCACCCGCCATTGCCTGCAACCGGGCACCGCCACCGAACATCGCTTGCGGGGCCTGTGGAGCGAAC
TGCTGGAACTGCCGGAAGCAGACATTTCCATCGATGACAGCTTCTTCAACCTCGGCGGCCATTCGATTCTGCTGTCGCGG
TTGCTGCTGGCGGTGCGCGAAGGTTTCGGCCAGGGCGTGGCGATCAATCGCTTCATCGAACAACCGACCCTGCAGCGGTT
GGGGGCGCTGCTCGATGGTGACGACACGGTGCAACAGCACTCGCTGGAGCGCCTGGAACAGGACGCCAACCGCGACCTCG
ACCTGCAGGTATTGCCAGTCGAGCGCCTGGGCGATGTGCACAAGGTGATCGTCACCGGGGCCAACAGCTTCCTCGGCGTG
CACCTGGTCGAAGCCCTGCTGGATTGGGGGGCGACCGAGGTGGCCTGCCTGGTGCGCAGTGCCGAGGGTGTGGATGCCGC
CGAGCGCTTTGCCCGGTCGCTGCGTGACAACCACATCACCCTCGACCTGTCGCGCATCAAGGTATTCGATGCCGACCTGC
GCAAGCCGCGCCTGGGCCTGGCAGAGGCCGATTACGACTACCTGGACGAAGGCTATGGGGCCCTGCTGCACAACGCCGCG
CAGGTCAACCATGTGCTCGATTACCAGGTACTGGCCGCCGACAACATCGAGCCGTTGTTCGAGTGCCTGCGCCTGTGCGA
GGGGCGGCGCAAGAAGATCTTCAACTTCGTCTCCACCCTCTCCGCCTGCAGTGCCGTGGACAGCCATGGCCAGGTACTGG
AGGACGGCCCGGCAAGCACCCCGCCGATCTACATCCGCAACGGCTACAACCTGAGCAAGTGGGTCGGCGAACGTATCCTC
AGCCGCGCCCGCGCACAGGGGGTGTGGGTCAACCTGTTCCGCCCGGGGAACATCACCTTCGACAGCCGTACCGGCGCCTG
CCAGCCCCAGCGCAATCGCCTGATGCTGATGCTCAAGGGCTCGTTGCAACTAGGGCAGGTACCAGGCCTGGAGATCGACT
TCGACCTGATGCCGGTGGACTTCCTCTCGCGCTTCATCGCCTTCCACAGCAGCCGCCACCAGGCCGGGCAATGCGTGTTC
AACCTGCACAACCCCGAGCCACTACGTTGGCGCGACTACCTGGCCTCGTTCCGTGAGCAGGGCCATGCCTTCGAGCTGGT
GAGCGTCGAGCAGTGGCAACACCAGTTGCGCCGGGTCGACCGCGACAACGCGCTGTACGACGTCCTGGGCTTCTACCTGG
ACGGTTTCGAGGAAGACATCGGCGACATCTCCGGGATTGTCCATGCCAACGCCCGTGACGGGGTACGGCGCATGGGTGCC
CATTACCCGAGCAAGAATCCCGAGCTGCTGCGCCGCGGCTGCCGGTACCTGGCCGACATCGGCTTCATCTGA

Upstream 100 bases:

>100_bases
TTGCTGGGCAACATCCTGCGCTTCTTCCGTGCCAGTTCGATGCTCGAGTCGACCTGCGTACAGCACGCCCTGCGCGACTA
CCTGCCCTGAGGACACCTGC

Downstream 100 bases:

>100_bases
CCCCTTTTCCACACAACAGGAGCAACACAGCATGCAAGCACTCAAACCCGATACCCTGATCCGCAACCCTGAAGGTTGCA
AGGTGGTCTCCCGTGTGGAA

Product: non ribosomal peptide synthethase, loading module

Products: pyrophosphate; AMP; enterobactin; pyrophosphate; L-Seryl-AMP [C]

Alternate protein names: ATP-dependent tryptophan adenylase; TrpA; Tryptophan activase; ATP-dependent D-leucine adenylase; D-LeuA; D-Leucine activase; Leucine racemase [ATP-hydrolyzing]; ATP-dependent tryptophan adenylase; TrpA; Tryptophan activase; ATP-dependent glycine adenylase; GlyA; Glycine activase; Linear gramicidin--PCP reductase [H]

Number of amino acids: Translated: 1143; Mature: 1143

Protein sequence:

>1143_residues
MRRLDILLVGNSPALGQLAHQLGEHGHGITIADNAETLRQQLVVRPHLVVEDGSLALNSSDWQSLDATPLLRLRLGASFA
ETLPRLETLCWCGSASAQRLIERLPVPSPASGNGQQLREDALQALNDLLALQVTRYARNPQYLQEAPAVSPGVQEREHGL
DWLEALAYRHPFNRTLRADLLEQAETGLIGQLEHSLRQHAERTALNRDGQRYSYGQLHARTVAIQRVLLPLLPEAGEHPP
VVAVCMAKSPELYASLLAILGCSAIYLPLDPATPAERRQRILADAKACVVLHDGQEPVGIAHLDVRALSIAEDAQLPSLA
QRPACAGQACVAIYTSGTTGLPKGVLLSQGNLAHFMAWYREHVALDRHSRVLQFSTIGFDASLLDILPTFACGAELVLPN
EDQRRDPQQLVRLIHSQAVTHAFLPPALLSILSRDTHLGLKHLVTGGDVCEPEVIVRLSGQCRMHNIYGPTETTVLATTR
VFASGESNRNLGLPIANTQVLILDEDLRPVTQQVAGELYITGPGVGLGYLNNPALTAERFVELCLPDGRALRAYRTGDIG
KWTTQGIELSGRRDNQVKIRGFRVEPEEIEHCLRDSQLFAQVAVVIDAQRRVLAFVAHGHGADAEQQLRAHAEQHLPDYM
RPMIYQVLEQMPYTANGKVDRQALSQRPLALPTRHCLQPGTATEHRLRGLWSELLELPEADISIDDSFFNLGGHSILLSR
LLLAVREGFGQGVAINRFIEQPTLQRLGALLDGDDTVQQHSLERLEQDANRDLDLQVLPVERLGDVHKVIVTGANSFLGV
HLVEALLDWGATEVACLVRSAEGVDAAERFARSLRDNHITLDLSRIKVFDADLRKPRLGLAEADYDYLDEGYGALLHNAA
QVNHVLDYQVLAADNIEPLFECLRLCEGRRKKIFNFVSTLSACSAVDSHGQVLEDGPASTPPIYIRNGYNLSKWVGERIL
SRARAQGVWVNLFRPGNITFDSRTGACQPQRNRLMLMLKGSLQLGQVPGLEIDFDLMPVDFLSRFIAFHSSRHQAGQCVF
NLHNPEPLRWRDYLASFREQGHAFELVSVEQWQHQLRRVDRDNALYDVLGFYLDGFEEDIGDISGIVHANARDGVRRMGA
HYPSKNPELLRRGCRYLADIGFI

Sequences:

>Translated_1143_residues
MRRLDILLVGNSPALGQLAHQLGEHGHGITIADNAETLRQQLVVRPHLVVEDGSLALNSSDWQSLDATPLLRLRLGASFA
ETLPRLETLCWCGSASAQRLIERLPVPSPASGNGQQLREDALQALNDLLALQVTRYARNPQYLQEAPAVSPGVQEREHGL
DWLEALAYRHPFNRTLRADLLEQAETGLIGQLEHSLRQHAERTALNRDGQRYSYGQLHARTVAIQRVLLPLLPEAGEHPP
VVAVCMAKSPELYASLLAILGCSAIYLPLDPATPAERRQRILADAKACVVLHDGQEPVGIAHLDVRALSIAEDAQLPSLA
QRPACAGQACVAIYTSGTTGLPKGVLLSQGNLAHFMAWYREHVALDRHSRVLQFSTIGFDASLLDILPTFACGAELVLPN
EDQRRDPQQLVRLIHSQAVTHAFLPPALLSILSRDTHLGLKHLVTGGDVCEPEVIVRLSGQCRMHNIYGPTETTVLATTR
VFASGESNRNLGLPIANTQVLILDEDLRPVTQQVAGELYITGPGVGLGYLNNPALTAERFVELCLPDGRALRAYRTGDIG
KWTTQGIELSGRRDNQVKIRGFRVEPEEIEHCLRDSQLFAQVAVVIDAQRRVLAFVAHGHGADAEQQLRAHAEQHLPDYM
RPMIYQVLEQMPYTANGKVDRQALSQRPLALPTRHCLQPGTATEHRLRGLWSELLELPEADISIDDSFFNLGGHSILLSR
LLLAVREGFGQGVAINRFIEQPTLQRLGALLDGDDTVQQHSLERLEQDANRDLDLQVLPVERLGDVHKVIVTGANSFLGV
HLVEALLDWGATEVACLVRSAEGVDAAERFARSLRDNHITLDLSRIKVFDADLRKPRLGLAEADYDYLDEGYGALLHNAA
QVNHVLDYQVLAADNIEPLFECLRLCEGRRKKIFNFVSTLSACSAVDSHGQVLEDGPASTPPIYIRNGYNLSKWVGERIL
SRARAQGVWVNLFRPGNITFDSRTGACQPQRNRLMLMLKGSLQLGQVPGLEIDFDLMPVDFLSRFIAFHSSRHQAGQCVF
NLHNPEPLRWRDYLASFREQGHAFELVSVEQWQHQLRRVDRDNALYDVLGFYLDGFEEDIGDISGIVHANARDGVRRMGA
HYPSKNPELLRRGCRYLADIGFI
>Mature_1143_residues
MRRLDILLVGNSPALGQLAHQLGEHGHGITIADNAETLRQQLVVRPHLVVEDGSLALNSSDWQSLDATPLLRLRLGASFA
ETLPRLETLCWCGSASAQRLIERLPVPSPASGNGQQLREDALQALNDLLALQVTRYARNPQYLQEAPAVSPGVQEREHGL
DWLEALAYRHPFNRTLRADLLEQAETGLIGQLEHSLRQHAERTALNRDGQRYSYGQLHARTVAIQRVLLPLLPEAGEHPP
VVAVCMAKSPELYASLLAILGCSAIYLPLDPATPAERRQRILADAKACVVLHDGQEPVGIAHLDVRALSIAEDAQLPSLA
QRPACAGQACVAIYTSGTTGLPKGVLLSQGNLAHFMAWYREHVALDRHSRVLQFSTIGFDASLLDILPTFACGAELVLPN
EDQRRDPQQLVRLIHSQAVTHAFLPPALLSILSRDTHLGLKHLVTGGDVCEPEVIVRLSGQCRMHNIYGPTETTVLATTR
VFASGESNRNLGLPIANTQVLILDEDLRPVTQQVAGELYITGPGVGLGYLNNPALTAERFVELCLPDGRALRAYRTGDIG
KWTTQGIELSGRRDNQVKIRGFRVEPEEIEHCLRDSQLFAQVAVVIDAQRRVLAFVAHGHGADAEQQLRAHAEQHLPDYM
RPMIYQVLEQMPYTANGKVDRQALSQRPLALPTRHCLQPGTATEHRLRGLWSELLELPEADISIDDSFFNLGGHSILLSR
LLLAVREGFGQGVAINRFIEQPTLQRLGALLDGDDTVQQHSLERLEQDANRDLDLQVLPVERLGDVHKVIVTGANSFLGV
HLVEALLDWGATEVACLVRSAEGVDAAERFARSLRDNHITLDLSRIKVFDADLRKPRLGLAEADYDYLDEGYGALLHNAA
QVNHVLDYQVLAADNIEPLFECLRLCEGRRKKIFNFVSTLSACSAVDSHGQVLEDGPASTPPIYIRNGYNLSKWVGERIL
SRARAQGVWVNLFRPGNITFDSRTGACQPQRNRLMLMLKGSLQLGQVPGLEIDFDLMPVDFLSRFIAFHSSRHQAGQCVF
NLHNPEPLRWRDYLASFREQGHAFELVSVEQWQHQLRRVDRDNALYDVLGFYLDGFEEDIGDISGIVHANARDGVRRMGA
HYPSKNPELLRRGCRYLADIGFI

Specific function: Activates the 13th to the 16th (Trp, D-Leu, Trp and Gly) amino acids in linear gramicidin and catalyzes the formation of the peptide bond between them. This enzyme is also responsible for the epimerization of the 14th (D-Leu) amino acid. It also catalyzes

COG id: COG1020

COG function: function code Q; Non-ribosomal peptide synthetase modules and related proteins

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 4 acyl carrier domains [H]

Homologues:

Organism=Homo sapiens, GI45580730, Length=434, Percent_Identity=24.4239631336406, Blast_Score=97, Evalue=8e-20,
Organism=Escherichia coli, GI1786801, Length=631, Percent_Identity=30.1109350237718, Blast_Score=205, Evalue=1e-53,
Organism=Escherichia coli, GI1788107, Length=350, Percent_Identity=25.4285714285714, Blast_Score=77, Evalue=8e-15,
Organism=Escherichia coli, GI145693145, Length=349, Percent_Identity=23.7822349570201, Blast_Score=69, Evalue=2e-12,
Organism=Escherichia coli, GI1786810, Length=364, Percent_Identity=24.1758241758242, Blast_Score=63, Evalue=1e-10,
Organism=Caenorhabditis elegans, GI17556356, Length=605, Percent_Identity=27.2727272727273, Blast_Score=160, Evalue=3e-39,
Organism=Caenorhabditis elegans, GI17550940, Length=476, Percent_Identity=24.7899159663866, Blast_Score=99, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI32564422, Length=519, Percent_Identity=23.6994219653179, Blast_Score=87, Evalue=7e-17,
Organism=Caenorhabditis elegans, GI32564420, Length=519, Percent_Identity=23.6994219653179, Blast_Score=87, Evalue=7e-17,
Organism=Caenorhabditis elegans, GI17538037, Length=372, Percent_Identity=24.7311827956989, Blast_Score=72, Evalue=1e-12,
Organism=Saccharomyces cerevisiae, GI6319591, Length=1053, Percent_Identity=24.8812915479582, Blast_Score=253, Evalue=1e-67,
Organism=Drosophila melanogaster, GI24648676, Length=527, Percent_Identity=31.1195445920304, Blast_Score=187, Evalue=5e-47,
Organism=Drosophila melanogaster, GI24653035, Length=364, Percent_Identity=24.7252747252747, Blast_Score=73, Evalue=1e-12,
Organism=Drosophila melanogaster, GI161076582, Length=365, Percent_Identity=24.1095890410959, Blast_Score=68, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010071
- InterPro:   IPR009081
- InterPro:   IPR020845
- InterPro:   IPR000873
- InterPro:   IPR001242
- InterPro:   IPR013120
- InterPro:   IPR016040
- InterPro:   IPR010060
- InterPro:   IPR006163
- InterPro:   IPR020806
- InterPro:   IPR006162
- InterPro:   IPR010080 [H]

Pfam domain/function: PF00501 AMP-binding; PF00668 Condensation; PF07993 NAD_binding_4; PF00550 PP-binding [H]

EC number: 2.7.7.- [C]

Molecular weight: Translated: 126752; Mature: 126752

Theoretical pI: Translated: 6.35; Mature: 6.35

Prosite motif: PS50075 ACP_DOMAIN ; PS00237 G_PROTEIN_RECEP_F1_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRRLDILLVGNSPALGQLAHQLGEHGHGITIADNAETLRQQLVVRPHLVVEDGSLALNSS
CCEEEEEEECCCCCHHHHHHHHCCCCCCEEEECCHHHHHHHHHHCCEEEEECCCEEECCC
DWQSLDATPLLRLRLGASFAETLPRLETLCWCGSASAQRLIERLPVPSPASGNGQQLRED
CCCCCCCCHHHHHHHCCHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCCCCHHHHHHH
ALQALNDLLALQVTRYARNPQYLQEAPAVSPGVQEREHGLDWLEALAYRHPFNRTLRADL
HHHHHHHHHHHHHHHHHCCCHHHHHCCCCCCCHHHHHCCHHHHHHHHHHCCCCHHHHHHH
LEQAETGLIGQLEHSLRQHAERTALNRDGQRYSYGQLHARTVAIQRVLLPLLPEAGEHPP
HHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCC
VVAVCMAKSPELYASLLAILGCSAIYLPLDPATPAERRQRILADAKACVVLHDGQEPVGI
EEEEEECCCHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHCCCEEEEEECCCCCCEE
AHLDVRALSIAEDAQLPSLAQRPACAGQACVAIYTSGTTGLPKGVLLSQGNLAHFMAWYR
EEECCEEEEHHHHCCCCHHHCCCCCCCCEEEEEEECCCCCCCCCEEECCCCHHHHHHHHH
EHVALDRHSRVLQFSTIGFDASLLDILPTFACGAELVLPNEDQRRDPQQLVRLIHSQAVT
HHHHHHHHCCEEEEEECCCCHHHHHHHHHHHCCCEEECCCCCCCCCHHHHHHHHHHHHHH
HAFLPPALLSILSRDTHLGLKHLVTGGDVCEPEVIVRLSGQCRMHNIYGPTETTVLATTR
HHHHHHHHHHHHCCCHHCCHHHHCCCCCCCCCEEEEEECCCEEEEECCCCCCCEEEEEEH
VFASGESNRNLGLPIANTQVLILDEDLRPVTQQVAGELYITGPGVGLGYLNNPALTAERF
HEECCCCCCCCCCEECCCEEEEECCCCHHHHHHHCCEEEEECCCCCCCCCCCCCHHHHHH
VELCLPDGRALRAYRTGDIGKWTTQGIELSGRRDNQVKIRGFRVEPEEIEHCLRDSQLFA
HHHHCCCCCEEEEEECCCCCCCCCCCEEECCCCCCEEEEEEEECCHHHHHHHHHHHHHHH
QVAVVIDAQRRVLAFVAHGHGADAEQQLRAHAEQHLPDYMRPMIYQVLEQMPYTANGKVD
HHHHHHHCCHHEEEEEECCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCCHH
RQALSQRPLALPTRHCLQPGTATEHRLRGLWSELLELPEADISIDDSFFNLGGHSILLSR
HHHHHCCCCCCCHHHHCCCCCCHHHHHHHHHHHHHHCCCCCCEECCHHHHCCCHHHHHHH
LLLAVREGFGQGVAINRFIEQPTLQRLGALLDGDDTVQQHSLERLEQDANRDLDLQVLPV
HHHHHHHCCCCCEEHHHHHCCHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCEEEECH
ERLGDVHKVIVTGANSFLGVHLVEALLDWGATEVACLVRSAEGVDAAERFARSLRDNHIT
HHHCCCEEEEEECCCHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCHHHHHHHHHCCCCEE
LDLSRIKVFDADLRKPRLGLAEADYDYLDEGYGALLHNAAQVNHVLDYQVLAADNIEPLF
EEEHHEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCEEEEECCCCHHHH
ECLRLCEGRRKKIFNFVSTLSACSAVDSHGQVLEDGPASTPPIYIRNGYNLSKWVGERIL
HHHHHHCHHHHHHHHHHHHHHHHHHHCCCCCEECCCCCCCCCEEEECCCCHHHHHHHHHH
SRARAQGVWVNLFRPGNITFDSRTGACQPQRNRLMLMLKGSLQLGQVPGLEIDFDLMPVD
HHHHHCCEEEEEEECCCEEECCCCCCCCCCCCCEEEEEECCCCCCCCCCCEEEEECCCHH
FLSRFIAFHSSRHQAGQCVFNLHNPEPLRWRDYLASFREQGHAFELVSVEQWQHQLRRVD
HHHHHHHHHCCCCCCCCEEEECCCCCCCHHHHHHHHHHHCCCEEEEEEHHHHHHHHHHCC
RDNALYDVLGFYLDGFEEDIGDISGIVHANARDGVRRMGAHYPSKNPELLRRGCRYLADI
CCCHHHHHHHHHHHHHHHHHHHHHHEEECCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHH
GFI
CCC
>Mature Secondary Structure
MRRLDILLVGNSPALGQLAHQLGEHGHGITIADNAETLRQQLVVRPHLVVEDGSLALNSS
CCEEEEEEECCCCCHHHHHHHHCCCCCCEEEECCHHHHHHHHHHCCEEEEECCCEEECCC
DWQSLDATPLLRLRLGASFAETLPRLETLCWCGSASAQRLIERLPVPSPASGNGQQLRED
CCCCCCCCHHHHHHHCCHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCCCCHHHHHHH
ALQALNDLLALQVTRYARNPQYLQEAPAVSPGVQEREHGLDWLEALAYRHPFNRTLRADL
HHHHHHHHHHHHHHHHHCCCHHHHHCCCCCCCHHHHHCCHHHHHHHHHHCCCCHHHHHHH
LEQAETGLIGQLEHSLRQHAERTALNRDGQRYSYGQLHARTVAIQRVLLPLLPEAGEHPP
HHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCC
VVAVCMAKSPELYASLLAILGCSAIYLPLDPATPAERRQRILADAKACVVLHDGQEPVGI
EEEEEECCCHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHCCCEEEEEECCCCCCEE
AHLDVRALSIAEDAQLPSLAQRPACAGQACVAIYTSGTTGLPKGVLLSQGNLAHFMAWYR
EEECCEEEEHHHHCCCCHHHCCCCCCCCEEEEEEECCCCCCCCCEEECCCCHHHHHHHHH
EHVALDRHSRVLQFSTIGFDASLLDILPTFACGAELVLPNEDQRRDPQQLVRLIHSQAVT
HHHHHHHHCCEEEEEECCCCHHHHHHHHHHHCCCEEECCCCCCCCCHHHHHHHHHHHHHH
HAFLPPALLSILSRDTHLGLKHLVTGGDVCEPEVIVRLSGQCRMHNIYGPTETTVLATTR
HHHHHHHHHHHHCCCHHCCHHHHCCCCCCCCCEEEEEECCCEEEEECCCCCCCEEEEEEH
VFASGESNRNLGLPIANTQVLILDEDLRPVTQQVAGELYITGPGVGLGYLNNPALTAERF
HEECCCCCCCCCCEECCCEEEEECCCCHHHHHHHCCEEEEECCCCCCCCCCCCCHHHHHH
VELCLPDGRALRAYRTGDIGKWTTQGIELSGRRDNQVKIRGFRVEPEEIEHCLRDSQLFA
HHHHCCCCCEEEEEECCCCCCCCCCCEEECCCCCCEEEEEEEECCHHHHHHHHHHHHHHH
QVAVVIDAQRRVLAFVAHGHGADAEQQLRAHAEQHLPDYMRPMIYQVLEQMPYTANGKVD
HHHHHHHCCHHEEEEEECCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCCHH
RQALSQRPLALPTRHCLQPGTATEHRLRGLWSELLELPEADISIDDSFFNLGGHSILLSR
HHHHHCCCCCCCHHHHCCCCCCHHHHHHHHHHHHHHCCCCCCEECCHHHHCCCHHHHHHH
LLLAVREGFGQGVAINRFIEQPTLQRLGALLDGDDTVQQHSLERLEQDANRDLDLQVLPV
HHHHHHHCCCCCEEHHHHHCCHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCEEEECH
ERLGDVHKVIVTGANSFLGVHLVEALLDWGATEVACLVRSAEGVDAAERFARSLRDNHIT
HHHCCCEEEEEECCCHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCHHHHHHHHHCCCCEE
LDLSRIKVFDADLRKPRLGLAEADYDYLDEGYGALLHNAAQVNHVLDYQVLAADNIEPLF
EEEHHEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCEEEEECCCCHHHH
ECLRLCEGRRKKIFNFVSTLSACSAVDSHGQVLEDGPASTPPIYIRNGYNLSKWVGERIL
HHHHHHCHHHHHHHHHHHHHHHHHHHCCCCCEECCCCCCCCCEEEECCCCHHHHHHHHHH
SRARAQGVWVNLFRPGNITFDSRTGACQPQRNRLMLMLKGSLQLGQVPGLEIDFDLMPVD
HHHHHCCEEEEEEECCCEEECCCCCCCCCCCCCEEEEEECCCCCCCCCCCEEEEECCCHH
FLSRFIAFHSSRHQAGQCVFNLHNPEPLRWRDYLASFREQGHAFELVSVEQWQHQLRRVD
HHHHHHHHHCCCCCCCCEEEECCCCCCCHHHHHHHHHHHCCCEEEEEEHHHHHHHHHHCC
RDNALYDVLGFYLDGFEEDIGDISGIVHANARDGVRRMGAHYPSKNPELLRRGCRYLADI
CCCHHHHHHHHHHHHHHHHHHHHHHEEECCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHH
GFI
CCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: Phosphopantetheine. [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 6 ATP; L-serine; 2,3-dihydroxybenzoate [C]

Specific reaction: 6 ATP + 3 L-serine + 3 2,3-dihydroxybenzoate = 6 pyrophosphate + 6 AMP + enterobactin ATP + L-serine = pyrophosphate + L-Seryl-AMP 6 ATP + 3 L-serine + 3 2,3-dihydroxybenzoate = 6 pyrophosphate + 6 AMP + enterobactin ATP + L-serine = pyrophosphate + L-Ser

General reaction: Transferases; Acyltransferases; Transferring groups other than amino-acyl groups [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA