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The map label for this gene is ubiB [H]

Identifier: 103488660

GI number: 103488660

Start: 3341075

End: 3342619

Strand: Reverse

Name: ubiB [H]

Synonym: Sala_3185

Alternate gene names: 103488660

Gene position: 3342619-3341075 (Counterclockwise)

Preceding gene: 103488661

Following gene: 103488659

Centisome position: 99.92

GC content: 67.7

Gene sequence:

>1545_bases
ATGACCCGTCCCGTCACCCATATCCTGCGCCTGCTGAAATGGGGCCGCATCCTCGCGCGCCACGGCGCGCTGCGCGGCAT
CGAGACGGCACCGGCGACGCCCCCAGGCGTCAAGCGGCTGTGCCGGATCGCACGGTTCGGCACGATCCAGCCCCGGATTC
CCGACTATGCCGCCGCCTTTCAGGCGATCGGGCCCGCCGCGGTCAAGCTGGGGCAGACGCTGGCGACGCGGCCCGACCTG
GTCGGCGAGGAAGCCGCGCGCAACCTGCTCACCCTGCAGGATGCGCTGCCCCCCGTCGCCTTCGCGCGCATCCGGGAGGA
GATCGAGGCGACCTTCGAAGCGCCGCTCGAAAGCCTCTATAGCGAGTTCGATCCCGATCCCGTCGGGTCGGCGTCGATCG
CACAGGTCCACCGCGCGGTCACCACCGACGGACGCCGCGTCGCGGTGAAGATTCGCCGACCCGGCATCGACAAGCAGTTC
GCGCGCGACATCGAAACCTATGAATGGGCCGCCGCGCATCTGGAGGCGCTCGGCGGCGAGGCGTCGCGGCTGCGCCCGCG
GCAGGTGATCGCCAATTTCCGCCGCTGGACCTTGCGCGAGCTCGACCTGCGGCGCGAAGCGGCCTCCGCGTCGGAACTGT
CCGATGCAATGGCGGCAATCCCCGAATATGAGGTGCCCGCGATCGATTGGGACCGCACCAACAGCCGCGTGATGACGATG
AGCTGGATCGACGGCATCAAGATTTCGGACCGCGACGCGCTGGTCGCCGCGGGGCATGACATGGAAAAGCTGGCGGCGAA
CCTGGTCCACGCCTTTTTGCGGCAGGCGATTGCCGAGGGGTTCTTCCATGCCGACATGCACCAGGGCAATTTGTTCGTGA
AGGCCGACGGGACGATCGCCGCGGTCGATTTCGGCATCATGGGGCGGATCAACCGCCAGGCGCGCTATTGGCTCGCCGAG
ATCCTCTATGGGCTGACGACCGGCAATTATCGTCGCGTCGCCGAAATCCATTTCGAGGCGCAATATGTGCCCGATTATCA
CAATGTCGACGAATTCGCGACCGCGCTGCGCGCGGTCGGCGAACCGATGCGCGGCAAGCCGGTGAGCGAGCTCAGCGTCG
GGCAGATGCTCGACGGGCTGTTCGCGATCACGCGCGATTTCGACATGCAGACGCAGCCGCACCTCCTCCTGCTTCAGAAA
ACGATGGTGATGGTCGAAGGCGTCGCGACGATGCTGAACCCCCGGATCAACATGTGGGACGTGTCGGGACCGTTTGTGAA
GGAGTGGATCCGCGACGAACTGGGGCCCGAGGCCGCGCTCGCCGACGGGCTGCGCGAGCAGGGCCGGACGCTGGCGCTGA
TCCCCGACATCATCCGCCGTCTCGATGAACAATTGCCGCGCAAGGGCGCCGCACCGCCCGCGCCGCCGCTGCCCGACGTC
ACGCTGATGTGGGAAAGAGGCGAGCGGCGCGTCTGGTGGCGCTATGCGCTCTCCGCGCTGATCGGCGCGGCGGCCGGGGC
CGCGGCGCTGAACTGGCTCGGTTGA

Upstream 100 bases:

>100_bases
CTGCGAAGGCAGGGGCCGATCTCCTTGGGACCGGTCATCGCCCCGGCGCCCGCTGGCTTCCCCCGTTCGCGGGCGCGGCG
ACGTGCAGAGCGGCGGCCGA

Downstream 100 bases:

>100_bases
TTCGGAAACCCGATGCGCATATCTTATGCGCAAGGAGAATGGCGATGAACCGTCCGGCGCGATTCGAAGGCCCGAAAAAA
CCGACCAATGTGTCGTTGAA

Product: 2-polyprenylphenol 6-hydroxylase

Products: 2-octaprenyl-6-hydroxyphenol [C]

Alternate protein names: NA

Number of amino acids: Translated: 514; Mature: 513

Protein sequence:

>514_residues
MTRPVTHILRLLKWGRILARHGALRGIETAPATPPGVKRLCRIARFGTIQPRIPDYAAAFQAIGPAAVKLGQTLATRPDL
VGEEAARNLLTLQDALPPVAFARIREEIEATFEAPLESLYSEFDPDPVGSASIAQVHRAVTTDGRRVAVKIRRPGIDKQF
ARDIETYEWAAAHLEALGGEASRLRPRQVIANFRRWTLRELDLRREAASASELSDAMAAIPEYEVPAIDWDRTNSRVMTM
SWIDGIKISDRDALVAAGHDMEKLAANLVHAFLRQAIAEGFFHADMHQGNLFVKADGTIAAVDFGIMGRINRQARYWLAE
ILYGLTTGNYRRVAEIHFEAQYVPDYHNVDEFATALRAVGEPMRGKPVSELSVGQMLDGLFAITRDFDMQTQPHLLLLQK
TMVMVEGVATMLNPRINMWDVSGPFVKEWIRDELGPEAALADGLREQGRTLALIPDIIRRLDEQLPRKGAAPPAPPLPDV
TLMWERGERRVWWRYALSALIGAAAGAAALNWLG

Sequences:

>Translated_514_residues
MTRPVTHILRLLKWGRILARHGALRGIETAPATPPGVKRLCRIARFGTIQPRIPDYAAAFQAIGPAAVKLGQTLATRPDL
VGEEAARNLLTLQDALPPVAFARIREEIEATFEAPLESLYSEFDPDPVGSASIAQVHRAVTTDGRRVAVKIRRPGIDKQF
ARDIETYEWAAAHLEALGGEASRLRPRQVIANFRRWTLRELDLRREAASASELSDAMAAIPEYEVPAIDWDRTNSRVMTM
SWIDGIKISDRDALVAAGHDMEKLAANLVHAFLRQAIAEGFFHADMHQGNLFVKADGTIAAVDFGIMGRINRQARYWLAE
ILYGLTTGNYRRVAEIHFEAQYVPDYHNVDEFATALRAVGEPMRGKPVSELSVGQMLDGLFAITRDFDMQTQPHLLLLQK
TMVMVEGVATMLNPRINMWDVSGPFVKEWIRDELGPEAALADGLREQGRTLALIPDIIRRLDEQLPRKGAAPPAPPLPDV
TLMWERGERRVWWRYALSALIGAAAGAAALNWLG
>Mature_513_residues
TRPVTHILRLLKWGRILARHGALRGIETAPATPPGVKRLCRIARFGTIQPRIPDYAAAFQAIGPAAVKLGQTLATRPDLV
GEEAARNLLTLQDALPPVAFARIREEIEATFEAPLESLYSEFDPDPVGSASIAQVHRAVTTDGRRVAVKIRRPGIDKQFA
RDIETYEWAAAHLEALGGEASRLRPRQVIANFRRWTLRELDLRREAASASELSDAMAAIPEYEVPAIDWDRTNSRVMTMS
WIDGIKISDRDALVAAGHDMEKLAANLVHAFLRQAIAEGFFHADMHQGNLFVKADGTIAAVDFGIMGRINRQARYWLAEI
LYGLTTGNYRRVAEIHFEAQYVPDYHNVDEFATALRAVGEPMRGKPVSELSVGQMLDGLFAITRDFDMQTQPHLLLLQKT
MVMVEGVATMLNPRINMWDVSGPFVKEWIRDELGPEAALADGLREQGRTLALIPDIIRRLDEQLPRKGAAPPAPPLPDVT
LMWERGERRVWWRYALSALIGAAAGAAALNWLG

Specific function: Required, probably indirectly, for the hydroxylation of 2-octaprenylphenol to 2-octaprenyl-6-hydroxy-phenol, the fourth step in ubiquinone biosynthesis [H]

COG id: COG0661

COG function: function code R; Predicted unusual protein kinase

Gene ontology:

Cell location: Cell inner membrane; Single-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ABC1 family. UbiB subfamily [H]

Homologues:

Organism=Homo sapiens, GI40254938, Length=273, Percent_Identity=29.3040293040293, Blast_Score=123, Evalue=4e-28,
Organism=Homo sapiens, GI41393593, Length=262, Percent_Identity=30.9160305343511, Blast_Score=121, Evalue=1e-27,
Organism=Homo sapiens, GI217035081, Length=260, Percent_Identity=28.0769230769231, Blast_Score=108, Evalue=2e-23,
Organism=Homo sapiens, GI27363457, Length=312, Percent_Identity=24.6794871794872, Blast_Score=74, Evalue=5e-13,
Organism=Homo sapiens, GI217416386, Length=269, Percent_Identity=25.2788104089219, Blast_Score=72, Evalue=1e-12,
Organism=Homo sapiens, GI34147522, Length=249, Percent_Identity=24.8995983935743, Blast_Score=72, Evalue=2e-12,
Organism=Escherichia coli, GI2367309, Length=383, Percent_Identity=37.3368146214099, Blast_Score=260, Evalue=1e-70,
Organism=Caenorhabditis elegans, GI17559152, Length=266, Percent_Identity=26.6917293233083, Blast_Score=103, Evalue=3e-22,
Organism=Caenorhabditis elegans, GI32565180, Length=311, Percent_Identity=23.1511254019293, Blast_Score=70, Evalue=3e-12,
Organism=Saccharomyces cerevisiae, GI6325148, Length=431, Percent_Identity=20.6496519721578, Blast_Score=85, Evalue=2e-17,
Organism=Saccharomyces cerevisiae, GI6321319, Length=382, Percent_Identity=24.869109947644, Blast_Score=77, Evalue=8e-15,
Organism=Drosophila melanogaster, GI24662575, Length=296, Percent_Identity=28.3783783783784, Blast_Score=128, Evalue=1e-29,
Organism=Drosophila melanogaster, GI22024280, Length=253, Percent_Identity=24.1106719367589, Blast_Score=90, Evalue=4e-18,
Organism=Drosophila melanogaster, GI18859849, Length=275, Percent_Identity=25.4545454545455, Blast_Score=70, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004147
- InterPro:   IPR011009
- InterPro:   IPR010232 [H]

Pfam domain/function: PF03109 ABC1 [H]

EC number: NA

Molecular weight: Translated: 57156; Mature: 57025

Theoretical pI: Translated: 7.14; Mature: 7.14

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTRPVTHILRLLKWGRILARHGALRGIETAPATPPGVKRLCRIARFGTIQPRIPDYAAAF
CCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCHHHHHH
QAIGPAAVKLGQTLATRPDLVGEEAARNLLTLQDALPPVAFARIREEIEATFEAPLESLY
HHCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHH
SEFDPDPVGSASIAQVHRAVTTDGRRVAVKIRRPGIDKQFARDIETYEWAAAHLEALGGE
HHCCCCCCCCHHHHHHHHHHCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCC
ASRLRPRQVIANFRRWTLRELDLRREAASASELSDAMAAIPEYEVPAIDWDRTNSRVMTM
HHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEE
SWIDGIKISDRDALVAAGHDMEKLAANLVHAFLRQAIAEGFFHADMHQGNLFVKADGTIA
EECCCCEECCCCCEEECCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCEEE
AVDFGIMGRINRQARYWLAEILYGLTTGNYRRVAEIHFEAQYVPDYHNVDEFATALRAVG
EEEHHHHHHCCHHHHHHHHHHHHHHCCCCCEEEEEEEEEEEECCCCCCHHHHHHHHHHHC
EPMRGKPVSELSVGQMLDGLFAITRDFDMQTQPHLLLLQKTMVMVEGVATMLNPRINMWD
CCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEE
VSGPFVKEWIRDELGPEAALADGLREQGRTLALIPDIIRRLDEQLPRKGAAPPAPPLPDV
CCCHHHHHHHHHHCCCHHHHHHHHHHCCCEEEHHHHHHHHHHHHCCCCCCCCCCCCCCCE
TLMWERGERRVWWRYALSALIGAAAGAAALNWLG
EEEEECCCCHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
TRPVTHILRLLKWGRILARHGALRGIETAPATPPGVKRLCRIARFGTIQPRIPDYAAAF
CCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCHHHHHH
QAIGPAAVKLGQTLATRPDLVGEEAARNLLTLQDALPPVAFARIREEIEATFEAPLESLY
HHCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHH
SEFDPDPVGSASIAQVHRAVTTDGRRVAVKIRRPGIDKQFARDIETYEWAAAHLEALGGE
HHCCCCCCCCHHHHHHHHHHCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCC
ASRLRPRQVIANFRRWTLRELDLRREAASASELSDAMAAIPEYEVPAIDWDRTNSRVMTM
HHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEE
SWIDGIKISDRDALVAAGHDMEKLAANLVHAFLRQAIAEGFFHADMHQGNLFVKADGTIA
EECCCCEECCCCCEEECCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCEEE
AVDFGIMGRINRQARYWLAEILYGLTTGNYRRVAEIHFEAQYVPDYHNVDEFATALRAVG
EEEHHHHHHCCHHHHHHHHHHHHHHCCCCCEEEEEEEEEEEECCCCCCHHHHHHHHHHHC
EPMRGKPVSELSVGQMLDGLFAITRDFDMQTQPHLLLLQKTMVMVEGVATMLNPRINMWD
CCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEE
VSGPFVKEWIRDELGPEAALADGLREQGRTLALIPDIIRRLDEQLPRKGAAPPAPPLPDV
CCCHHHHHHHHHHCCCHHHHHHHHHHCCCEEEHHHHHHHHHHHHCCCCCCCCCCCCCCCE
TLMWERGERRVWWRYALSALIGAAAGAAALNWLG
EEEEECCCCHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 2 2-octaprenylphenol; O2 [C]

Specific reaction: 2 2-octaprenylphenol + O2 = 2 2-octaprenyl-6-hydroxyphenol [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA