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The map label for this gene is acdA [H]

Identifier: 103488634

GI number: 103488634

Start: 3307074

End: 3308228

Strand: Reverse

Name: acdA [H]

Synonym: Sala_3159

Alternate gene names: 103488634

Gene position: 3308228-3307074 (Counterclockwise)

Preceding gene: 103488637

Following gene: 103488633

Centisome position: 98.9

GC content: 62.94

Gene sequence:

>1155_bases
ATGTCGCTCGATAGCCTCTCGCGCACCGCCTATACCGACGATCATGAGGCCTTCCGTTCGACGGTCCGCCAGTTCCTCGA
AAAGGAAGTCGCGCCCAACCAGGCGCAATGGGCCGAGGACGGCATCGTGCCCAAGAGCCTGTGGCCCAAGGCCGGCGAGC
TGGGCCTGCTCTGTCCGACGGTGCCCGAGGAATATGGCGGGCTGGGCCTCGACTTCGGCTACAACGCGATCGTCGACGAG
GAAAGCGCCTATTATGGCCGCGTGACGACGGGCTTTTCGCTCCAGTCGGACATCGTGACCAACTATATCGTCCGCTATGG
CAGCGAGGAGCAGAAGAAGCACTGGCTGCCCAAAATGGTGTCGGGCGAGGTGATCACCGCGATCGCGATGACCGAACCGG
GCACCGGCAGCGACCTGCAGGGGATGCGCACGACCGCGAAAAAGGATGGCAACCATTATGTCATCAACGGGTCGAAAACC
TATATCACCAACGGCCAGAACGCCGACCTGATCCTCGTCTGCGTCAAGACCGATCCCGACGCCCGGCCCGCGTGGAAGGG
CGTGTCGATCGTGCTCGTCGAAGCCGACCGCGATGGGTTCGAGCGCGGCCGCAACCTCGACAAGATCGGACAGGACGAGG
CCGATACGTCCGAGCTGTTCTTCAACGATGTGCGCGTGCCGATCACCAATTGCCTCGGCGAAGAGGGGCAGGGTTTCATC
TATCTGATGAGCGAGCTTCCGCAGGAACGCCTCTCGATCGCGATCAGCGCGCAGGCCTCGGCGCAGCGCGCCTTCGACGA
CACGGTCGAATATACGCGCGAGCGCAAGGCGTTCGGCAAGCCGATCCTCGATTTCCAGAACAGCCGCTTCGTGCTCGCTG
ATCTGAAGGCGAAATTGCAGGTCGGCTGGGCGCATCTCGACTGGGCGCTCGCGCGGCACCTGAAGAAGGAACTCACCCCC
GAAGAGGGCGCCGCGGCGAAGCTGTGGCACACCGAACTGCAATGGGAGGTGATGGACAAATGCCTCCAGCTGTTCGGCGG
CGCGGGTTATATGAACGAATATCCGATCGCCCGCGCCTGGCGCGCGGCGCGCGTGACGCGCATCTTCGGCGGCACGAACG
AGATCATGAAGGAACTGATCGGGCGGAAGCTTTAG

Upstream 100 bases:

>100_bases
ATTTTTACTTGACGTGGACGTAAACGTAAGGTCTCTTGACGATCAAAGATGCGGCCGACTCCCCGGCTTCGTTCGGCCGC
GCCCAAGGGAAAGGAACCAG

Downstream 100 bases:

>100_bases
GCCGTCGCCCCAGCGAAAGCTGGGGCCGCCATCGTCCGAAAACCATCGAGCGATCCCAGCTTTCGCTGGGATGACGAACA
GGAAACGAAAGGACTCCCAA

Product: acyl-CoA dehydrogenase-like protein

Products: 2,3-dehydroacyl-CoA; reduced acceptor

Alternate protein names: NA

Number of amino acids: Translated: 384; Mature: 383

Protein sequence:

>384_residues
MSLDSLSRTAYTDDHEAFRSTVRQFLEKEVAPNQAQWAEDGIVPKSLWPKAGELGLLCPTVPEEYGGLGLDFGYNAIVDE
ESAYYGRVTTGFSLQSDIVTNYIVRYGSEEQKKHWLPKMVSGEVITAIAMTEPGTGSDLQGMRTTAKKDGNHYVINGSKT
YITNGQNADLILVCVKTDPDARPAWKGVSIVLVEADRDGFERGRNLDKIGQDEADTSELFFNDVRVPITNCLGEEGQGFI
YLMSELPQERLSIAISAQASAQRAFDDTVEYTRERKAFGKPILDFQNSRFVLADLKAKLQVGWAHLDWALARHLKKELTP
EEGAAAKLWHTELQWEVMDKCLQLFGGAGYMNEYPIARAWRAARVTRIFGGTNEIMKELIGRKL

Sequences:

>Translated_384_residues
MSLDSLSRTAYTDDHEAFRSTVRQFLEKEVAPNQAQWAEDGIVPKSLWPKAGELGLLCPTVPEEYGGLGLDFGYNAIVDE
ESAYYGRVTTGFSLQSDIVTNYIVRYGSEEQKKHWLPKMVSGEVITAIAMTEPGTGSDLQGMRTTAKKDGNHYVINGSKT
YITNGQNADLILVCVKTDPDARPAWKGVSIVLVEADRDGFERGRNLDKIGQDEADTSELFFNDVRVPITNCLGEEGQGFI
YLMSELPQERLSIAISAQASAQRAFDDTVEYTRERKAFGKPILDFQNSRFVLADLKAKLQVGWAHLDWALARHLKKELTP
EEGAAAKLWHTELQWEVMDKCLQLFGGAGYMNEYPIARAWRAARVTRIFGGTNEIMKELIGRKL
>Mature_383_residues
SLDSLSRTAYTDDHEAFRSTVRQFLEKEVAPNQAQWAEDGIVPKSLWPKAGELGLLCPTVPEEYGGLGLDFGYNAIVDEE
SAYYGRVTTGFSLQSDIVTNYIVRYGSEEQKKHWLPKMVSGEVITAIAMTEPGTGSDLQGMRTTAKKDGNHYVINGSKTY
ITNGQNADLILVCVKTDPDARPAWKGVSIVLVEADRDGFERGRNLDKIGQDEADTSELFFNDVRVPITNCLGEEGQGFIY
LMSELPQERLSIAISAQASAQRAFDDTVEYTRERKAFGKPILDFQNSRFVLADLKAKLQVGWAHLDWALARHLKKELTPE
EGAAAKLWHTELQWEVMDKCLQLFGGAGYMNEYPIARAWRAARVTRIFGGTNEIMKELIGRKL

Specific function: Involved in the degradation of long-chain fatty acids [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4501857, Length=377, Percent_Identity=47.4801061007958, Blast_Score=355, Evalue=5e-98,
Organism=Homo sapiens, GI226958412, Length=375, Percent_Identity=37.0666666666667, Blast_Score=248, Evalue=9e-66,
Organism=Homo sapiens, GI226958414, Length=339, Percent_Identity=38.0530973451327, Blast_Score=239, Evalue=3e-63,
Organism=Homo sapiens, GI4557233, Length=376, Percent_Identity=37.7659574468085, Blast_Score=224, Evalue=7e-59,
Organism=Homo sapiens, GI4557231, Length=379, Percent_Identity=33.509234828496, Blast_Score=213, Evalue=2e-55,
Organism=Homo sapiens, GI187960098, Length=379, Percent_Identity=33.509234828496, Blast_Score=213, Evalue=2e-55,
Organism=Homo sapiens, GI4501859, Length=376, Percent_Identity=31.6489361702128, Blast_Score=206, Evalue=3e-53,
Organism=Homo sapiens, GI7656849, Length=374, Percent_Identity=30.4812834224599, Blast_Score=200, Evalue=2e-51,
Organism=Homo sapiens, GI21361497, Length=371, Percent_Identity=33.6927223719677, Blast_Score=196, Evalue=2e-50,
Organism=Homo sapiens, GI4557235, Length=367, Percent_Identity=31.8801089918256, Blast_Score=176, Evalue=2e-44,
Organism=Homo sapiens, GI76496475, Length=367, Percent_Identity=31.8801089918256, Blast_Score=176, Evalue=2e-44,
Organism=Homo sapiens, GI4503943, Length=379, Percent_Identity=26.3852242744063, Blast_Score=119, Evalue=5e-27,
Organism=Homo sapiens, GI211971008, Length=291, Percent_Identity=30.9278350515464, Blast_Score=115, Evalue=6e-26,
Organism=Homo sapiens, GI48976061, Length=291, Percent_Identity=30.9278350515464, Blast_Score=115, Evalue=7e-26,
Organism=Homo sapiens, GI7669494, Length=353, Percent_Identity=26.9121813031161, Blast_Score=112, Evalue=6e-25,
Organism=Homo sapiens, GI38505218, Length=323, Percent_Identity=28.4829721362229, Blast_Score=105, Evalue=8e-23,
Organism=Escherichia coli, GI87081958, Length=380, Percent_Identity=29.4736842105263, Blast_Score=158, Evalue=7e-40,
Organism=Escherichia coli, GI1786223, Length=378, Percent_Identity=28.3068783068783, Blast_Score=137, Evalue=1e-33,
Organism=Escherichia coli, GI87082384, Length=283, Percent_Identity=25.4416961130742, Blast_Score=76, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI17538396, Length=376, Percent_Identity=36.1702127659575, Blast_Score=236, Evalue=1e-62,
Organism=Caenorhabditis elegans, GI17551932, Length=375, Percent_Identity=35.7333333333333, Blast_Score=233, Evalue=1e-61,
Organism=Caenorhabditis elegans, GI17570075, Length=383, Percent_Identity=33.420365535248, Blast_Score=224, Evalue=7e-59,
Organism=Caenorhabditis elegans, GI17505929, Length=373, Percent_Identity=35.1206434316354, Blast_Score=219, Evalue=2e-57,
Organism=Caenorhabditis elegans, GI17533517, Length=377, Percent_Identity=34.2175066312997, Blast_Score=216, Evalue=1e-56,
Organism=Caenorhabditis elegans, GI17534899, Length=374, Percent_Identity=32.8877005347594, Blast_Score=213, Evalue=1e-55,
Organism=Caenorhabditis elegans, GI17569725, Length=368, Percent_Identity=33.695652173913, Blast_Score=208, Evalue=4e-54,
Organism=Caenorhabditis elegans, GI17508101, Length=374, Percent_Identity=31.5508021390374, Blast_Score=201, Evalue=5e-52,
Organism=Caenorhabditis elegans, GI17506239, Length=374, Percent_Identity=31.283422459893, Blast_Score=190, Evalue=1e-48,
Organism=Caenorhabditis elegans, GI71990804, Length=280, Percent_Identity=36.0714285714286, Blast_Score=162, Evalue=3e-40,
Organism=Caenorhabditis elegans, GI71985184, Length=349, Percent_Identity=30.945558739255, Blast_Score=161, Evalue=5e-40,
Organism=Caenorhabditis elegans, GI71982178, Length=265, Percent_Identity=34.3396226415094, Blast_Score=151, Evalue=7e-37,
Organism=Caenorhabditis elegans, GI32563615, Length=227, Percent_Identity=35.6828193832599, Blast_Score=149, Evalue=3e-36,
Organism=Caenorhabditis elegans, GI71985192, Length=266, Percent_Identity=31.9548872180451, Blast_Score=125, Evalue=3e-29,
Organism=Caenorhabditis elegans, GI17534353, Length=383, Percent_Identity=28.1984334203655, Blast_Score=123, Evalue=1e-28,
Organism=Caenorhabditis elegans, GI17562446, Length=289, Percent_Identity=28.719723183391, Blast_Score=112, Evalue=4e-25,
Organism=Caenorhabditis elegans, GI17531909, Length=241, Percent_Identity=26.9709543568465, Blast_Score=97, Evalue=1e-20,
Organism=Drosophila melanogaster, GI21355753, Length=376, Percent_Identity=35.3723404255319, Blast_Score=223, Evalue=1e-58,
Organism=Drosophila melanogaster, GI24660351, Length=380, Percent_Identity=33.6842105263158, Blast_Score=212, Evalue=3e-55,
Organism=Drosophila melanogaster, GI21356377, Length=378, Percent_Identity=33.5978835978836, Blast_Score=209, Evalue=2e-54,
Organism=Drosophila melanogaster, GI24646207, Length=373, Percent_Identity=34.0482573726542, Blast_Score=195, Evalue=6e-50,
Organism=Drosophila melanogaster, GI24666513, Length=377, Percent_Identity=30.7692307692308, Blast_Score=189, Evalue=2e-48,
Organism=Drosophila melanogaster, GI281363737, Length=379, Percent_Identity=31.9261213720317, Blast_Score=179, Evalue=3e-45,
Organism=Drosophila melanogaster, GI19920834, Length=376, Percent_Identity=27.6595744680851, Blast_Score=123, Evalue=2e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: 1.3.99.3

Molecular weight: Translated: 42929; Mature: 42798

Theoretical pI: Translated: 5.01; Mature: 5.01

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLDSLSRTAYTDDHEAFRSTVRQFLEKEVAPNQAQWAEDGIVPKSLWPKAGELGLLCPT
CCCCCCCHHCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCCHHCCCCCCCCCEECCC
VPEEYGGLGLDFGYNAIVDEESAYYGRVTTGFSLQSDIVTNYIVRYGSEEQKKHWLPKMV
CCHHHCCEEECCCCCEEECCCCCEECEEECCCCHHHHHHHHHHHHCCCCHHHHHHCCHHH
SGEVITAIAMTEPGTGSDLQGMRTTAKKDGNHYVINGSKTYITNGQNADLILVCVKTDPD
CCCEEEEEEEECCCCCCCCHHHHHHHHCCCCEEEECCCEEEEECCCCCCEEEEEEECCCC
ARPAWKGVSIVLVEADRDGFERGRNLDKIGQDEADTSELFFNDVRVPITNCLGEEGQGFI
CCCCCCCEEEEEEECCCCHHHHCCCHHHCCCCCCCHHHHHHHCCCCHHHHHCCCCCCCEE
YLMSELPQERLSIAISAQASAQRAFDDTVEYTRERKAFGKPILDFQNSRFVLADLKAKLQ
EEHHHCCHHHHEEEEECCHHHHHHHHHHHHHHHHHHHHCCCCEECCCCEEEEEECHHHHE
VGWAHLDWALARHLKKELTPEEGAAAKLWHTELQWEVMDKCLQLFGGAGYMNEYPIARAW
ECHHHHHHHHHHHHHHHCCCCCCCEEEHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHH
RAARVTRIFGGTNEIMKELIGRKL
HHHHHHHHHCCHHHHHHHHHCCCC
>Mature Secondary Structure 
SLDSLSRTAYTDDHEAFRSTVRQFLEKEVAPNQAQWAEDGIVPKSLWPKAGELGLLCPT
CCCCCCHHCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCCHHCCCCCCCCCEECCC
VPEEYGGLGLDFGYNAIVDEESAYYGRVTTGFSLQSDIVTNYIVRYGSEEQKKHWLPKMV
CCHHHCCEEECCCCCEEECCCCCEECEEECCCCHHHHHHHHHHHHCCCCHHHHHHCCHHH
SGEVITAIAMTEPGTGSDLQGMRTTAKKDGNHYVINGSKTYITNGQNADLILVCVKTDPD
CCCEEEEEEEECCCCCCCCHHHHHHHHCCCCEEEECCCEEEEECCCCCCEEEEEEECCCC
ARPAWKGVSIVLVEADRDGFERGRNLDKIGQDEADTSELFFNDVRVPITNCLGEEGQGFI
CCCCCCCEEEEEEECCCCHHHHCCCHHHCCCCCCCHHHHHHHCCCCHHHHHCCCCCCCEE
YLMSELPQERLSIAISAQASAQRAFDDTVEYTRERKAFGKPILDFQNSRFVLADLKAKLQ
EEHHHCCHHHHEEEEECCHHHHHHHHHHHHHHHHHHHHCCCCEECCCCEEEEEECHHHHE
VGWAHLDWALARHLKKELTPEEGAAAKLWHTELQWEVMDKCLQLFGGAGYMNEYPIARAW
ECHHHHHHHHHHHHHHHCCCCCCCEEEHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHH
RAARVTRIFGGTNEIMKELIGRKL
HHHHHHHHHCCHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: acyl-CoA; acceptor

Specific reaction: acyl-CoA + acceptor = 2,3-dehydroacyl-CoA + reduced acceptor

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9353933; 9384377 [H]