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The map label for this gene is fabH [H]

Identifier: 103488620

GI number: 103488620

Start: 3296312

End: 3297448

Strand: Direct

Name: fabH [H]

Synonym: Sala_3145

Alternate gene names: 103488620

Gene position: 3296312-3297448 (Clockwise)

Preceding gene: 103488618

Following gene: 103488625

Centisome position: 98.54

GC content: 62.71

Gene sequence:

>1137_bases
ATGTCGCACGCACCGCAGCCGGTCCTTTCCGCCACCGGCCTCTTCACCCCCGCCGAACGCATCTCCAACGAAGAACTTGT
CGCCAGTTTTAATCGGTATGTTGCGCTGCACAATAGAAAAAATGCTGCCGCGATCGCCGCGGGCGAGATGGAAGAACTGA
CCGAATCGAGCGTCGAGTTCATCGAAAAGGCGAGCGGGATCGGCTCGCGCCATGTTGTCGACAAGGCGGGCATTCTCGAT
CCCGAACATATGGCGCCGCGCCTGCCCGAACGTGGCAACGGGGAGCTGTCGATCCTCGCCGAAATCGGCGTCGCGGCGGC
GAAGGACGCGCTCGCGCGCGCGGGCCGCGATGCGGGCGACGTCGATGCCGTGCTCTGTGCAGCGTCGAACATGCAGCGCG
CCTATCCGGCGATGGCGATCGAAATCCAGGACGCGCTCGGCATCGACGGTTTCGGGTTCGACATGAATGTCGCCTGCTCG
TCGGCGACCTTCGGCATCCAGACCGCCGCCGATTATATCCGCGCGGGTCACGCGCGGAGCGTGCTCGTCGTGAACCCCGA
AATCTGTTCGGGGCATCTGAACTGGCGCGACCGCGACAGCCATTTCATCTTCGGCGACGTCGCGACCGCCATCCTTGTCG
AGGACAGGGCGATCGCGCCCGACGGCCATTGGGACATCCTCGGCACCAGATTGAAGACCGTCTTTTCGAACAATATCCGT
AACAATTTCGGCTTCCTCAACCGCACGCATGGCGGGATCGACCAGTCGGGACCGAAAACCGACAAGCTCTTCGTCCAGGA
GGGGCGCAAGGTGTTCAAGGAAGTCGTGCCGATGGTCGCCAGCATGATCGTCGGGGAAATGGAAAAGCTGGGGCTGGAGG
GCCGCGACATGCGGCGGCTGTGGCTCCATCAGGCGAATGTCAACATGAACCGGCTGATCGCGCATCGCGTTCTGGGGCAC
GAGGCGAGCGAGGACGAAAGCCCGATCGTGCTCGACACCTATGGCAACACATCGAGCGCAGGGTCGATCATCGCCTTTCA
CCTCCACCATGAGGATATGGTCGCGGGCGACACCGGGCTGATCTGTTCGTTCGGGGCGGGTTACAGCGCGGGGACGGTGT
TCGTTCGGAAGACGTGA

Upstream 100 bases:

>100_bases
ACCATCGCGTCGGCGCGCATTCAGCCCATGCCGGGGCGTTGCGCGGCGTCGCGACCGGGCCTAATCCTCGTGCCCCGAAC
CATTAGACACGAGAGCCGCC

Downstream 100 bases:

>100_bases
GTCAGAAATCGTCGTCCCCGCGAAGGCGGGGACCGCTGTCGGCGTAGCGCAAGGTTGCTGGCGGCCCCCGCCTTCGCGGG
GGCACAGGCTGCATATCACA

Product: 3-oxoacyl-(acyl carrier protein) synthase III

Products: NA

Alternate protein names: 3-oxoacyl-[acyl-carrier-protein] synthase III; Beta-ketoacyl-ACP synthase III; KAS III [H]

Number of amino acids: Translated: 378; Mature: 377

Protein sequence:

>378_residues
MSHAPQPVLSATGLFTPAERISNEELVASFNRYVALHNRKNAAAIAAGEMEELTESSVEFIEKASGIGSRHVVDKAGILD
PEHMAPRLPERGNGELSILAEIGVAAAKDALARAGRDAGDVDAVLCAASNMQRAYPAMAIEIQDALGIDGFGFDMNVACS
SATFGIQTAADYIRAGHARSVLVVNPEICSGHLNWRDRDSHFIFGDVATAILVEDRAIAPDGHWDILGTRLKTVFSNNIR
NNFGFLNRTHGGIDQSGPKTDKLFVQEGRKVFKEVVPMVASMIVGEMEKLGLEGRDMRRLWLHQANVNMNRLIAHRVLGH
EASEDESPIVLDTYGNTSSAGSIIAFHLHHEDMVAGDTGLICSFGAGYSAGTVFVRKT

Sequences:

>Translated_378_residues
MSHAPQPVLSATGLFTPAERISNEELVASFNRYVALHNRKNAAAIAAGEMEELTESSVEFIEKASGIGSRHVVDKAGILD
PEHMAPRLPERGNGELSILAEIGVAAAKDALARAGRDAGDVDAVLCAASNMQRAYPAMAIEIQDALGIDGFGFDMNVACS
SATFGIQTAADYIRAGHARSVLVVNPEICSGHLNWRDRDSHFIFGDVATAILVEDRAIAPDGHWDILGTRLKTVFSNNIR
NNFGFLNRTHGGIDQSGPKTDKLFVQEGRKVFKEVVPMVASMIVGEMEKLGLEGRDMRRLWLHQANVNMNRLIAHRVLGH
EASEDESPIVLDTYGNTSSAGSIIAFHLHHEDMVAGDTGLICSFGAGYSAGTVFVRKT
>Mature_377_residues
SHAPQPVLSATGLFTPAERISNEELVASFNRYVALHNRKNAAAIAAGEMEELTESSVEFIEKASGIGSRHVVDKAGILDP
EHMAPRLPERGNGELSILAEIGVAAAKDALARAGRDAGDVDAVLCAASNMQRAYPAMAIEIQDALGIDGFGFDMNVACSS
ATFGIQTAADYIRAGHARSVLVVNPEICSGHLNWRDRDSHFIFGDVATAILVEDRAIAPDGHWDILGTRLKTVFSNNIRN
NFGFLNRTHGGIDQSGPKTDKLFVQEGRKVFKEVVPMVASMIVGEMEKLGLEGRDMRRLWLHQANVNMNRLIAHRVLGHE
ASEDESPIVLDTYGNTSSAGSIIAFHLHHEDMVAGDTGLICSFGAGYSAGTVFVRKT

Specific function: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the

COG id: COG0332

COG function: function code I; 3-oxoacyl-[acyl-carrier-protein] synthase III

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fabH family [H]

Homologues:

Organism=Escherichia coli, GI1787333, Length=347, Percent_Identity=26.2247838616715, Blast_Score=94, Evalue=2e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013751
- InterPro:   IPR013747
- InterPro:   IPR004655
- InterPro:   IPR016039
- InterPro:   IPR016038 [H]

Pfam domain/function: PF08545 ACP_syn_III; PF08541 ACP_syn_III_C [H]

EC number: =2.3.1.180 [H]

Molecular weight: Translated: 40746; Mature: 40614

Theoretical pI: Translated: 5.84; Mature: 5.84

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSHAPQPVLSATGLFTPAERISNEELVASFNRYVALHNRKNAAAIAAGEMEELTESSVEF
CCCCCCCHHHHCCCCCCHHHCCCHHHHHHHHHEEEEECCCCCEEEECCCHHHHHHHHHHH
IEKASGIGSRHVVDKAGILDPEHMAPRLPERGNGELSILAEIGVAAAKDALARAGRDAGD
HHHHCCCCCCHHHHHCCCCCHHHHCCCCCCCCCCCEEEEEHHCHHHHHHHHHHCCCCCCC
VDAVLCAASNMQRAYPAMAIEIQDALGIDGFGFDMNVACSSATFGIQTAADYIRAGHARS
HHHHHHHHHCHHHHCCEEEEEEHHHCCCCCCCCCCEEEECCCCCCHHHHHHHHHCCCCCE
VLVVNPEICSGHLNWRDRDSHFIFGDVATAILVEDRAIAPDGHWDILGTRLKTVFSNNIR
EEEECHHHHCCCCCCCCCCCCEEEHHHHEEEEEECCEECCCCCHHHHHHHHHHHHHHCCC
NNFGFLNRTHGGIDQSGPKTDKLFVQEGRKVFKEVVPMVASMIVGEMEKLGLEGRDMRRL
CCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHH
WLHQANVNMNRLIAHRVLGHEASEDESPIVLDTYGNTSSAGSIIAFHLHHEDMVAGDTGL
HHHHCCCCHHHHHHHHHHCCCCCCCCCCEEEECCCCCCCCCCEEEEEEECCHHCCCCCCE
ICSFGAGYSAGTVFVRKT
EEECCCCCCCCEEEEEEC
>Mature Secondary Structure 
SHAPQPVLSATGLFTPAERISNEELVASFNRYVALHNRKNAAAIAAGEMEELTESSVEF
CCCCCCHHHHCCCCCCHHHCCCHHHHHHHHHEEEEECCCCCEEEECCCHHHHHHHHHHH
IEKASGIGSRHVVDKAGILDPEHMAPRLPERGNGELSILAEIGVAAAKDALARAGRDAGD
HHHHCCCCCCHHHHHCCCCCHHHHCCCCCCCCCCCEEEEEHHCHHHHHHHHHHCCCCCCC
VDAVLCAASNMQRAYPAMAIEIQDALGIDGFGFDMNVACSSATFGIQTAADYIRAGHARS
HHHHHHHHHCHHHHCCEEEEEEHHHCCCCCCCCCCEEEECCCCCCHHHHHHHHHCCCCCE
VLVVNPEICSGHLNWRDRDSHFIFGDVATAILVEDRAIAPDGHWDILGTRLKTVFSNNIR
EEEECHHHHCCCCCCCCCCCCEEEHHHHEEEEEECCEECCCCCHHHHHHHHHHHHHHCCC
NNFGFLNRTHGGIDQSGPKTDKLFVQEGRKVFKEVVPMVASMIVGEMEKLGLEGRDMRRL
CCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHH
WLHQANVNMNRLIAHRVLGHEASEDESPIVLDTYGNTSSAGSIIAFHLHHEDMVAGDTGL
HHHHCCCCHHHHHHHHHHCCCCCCCCCCEEEECCCCCCCCCCEEEEEEECCHHCCCCCCE
ICSFGAGYSAGTVFVRKT
EEECCCCCCCCEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA