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The map label for this gene is yngJ [H]

Identifier: 103488550

GI number: 103488550

Start: 3224331

End: 3225620

Strand: Reverse

Name: yngJ [H]

Synonym: Sala_3074

Alternate gene names: 103488550

Gene position: 3225620-3224331 (Counterclockwise)

Preceding gene: 103488551

Following gene: 103488549

Centisome position: 96.43

GC content: 64.88

Gene sequence:

>1290_bases
ATGGATTTCGATCTCACCGAACGGCAGGCGCATTGGCAGGGCCGTGTGCGCGAGTTCATCGAACGCAAGGTCCGCCCCGC
GGTGCCGACCTATTATGAACAGGATGCGGCGGGCGATCGCTGGAAGGTCATCCAGGTCGTCGAGGATCTGAAGGCCGAGG
CGAAGGCCGCGGGCATCTGGAACCTGTTCATGCCGCCGCGCAGCGCCGCGCACCACCATGTCGACGACACTTTCGAGTTC
GAGGGGCCGGGGCTTACCAATCTTGAATATGCGCTGTGCGCCGAGGAAATGGGGCGCATCGGCTTTGCGAGCGAGGTCTT
CAACTGCTCGGCGCCCGACACGGGCAATATGGAGGTGTTCCACCGTTACGGCACGCGCGCGCAGAAGGACAGATGGCTGA
AGCCGCTGATGAACGGCGAGATCCGGTCGGCCTTCCTGATGACCGAACCCGCGGTCGCCTCGTCCGACGCGACGAATATC
GAGACGCGGATCGAGCGCGACGGCGACGATTATATCATCAACGGCACCAAATGGTGGTCGTCGGGCGCGGGCGATCCGCG
CTGCAAGGTCGCGATCGTGATGGGCAAGACCGATTTCGGCGCCAAGCGTCACGCGCAGCAGTCGATGCTGGTCGTGCCGC
TCGACGCGCCGGGGGTCACGATCAAGCGCCACCTGCCCGTCTTCGGCTATGACGATGCGCCGCACGGCCATATGGAAATC
GAGCTGAAGGACGTCCGGGTCAATGCCGAGGAGGCGATGCTGCTCGGCGAAGGCCGCGGTTTCGAAATCGCGCAGGGCCG
TCTGGGGCCGGGTCGCATCCACCACTGTATGCGCACGATCGGCGTCGCCGAAGAGGCGCTGGAAAAGATGTGCAAGCGGC
TCCAGTCGCGCGTCGCCTTCGGCAAGACGATCGCCGAGCAGAGCATCTGGGAACAGCGGATCGCGCGCGCGCGTATCGAT
ATCGAGATGACGCGCCTCCTCTGCCTGAAGGCCGCCGACATGATGGACAAGATCGGCAACAAGTCGGCCGCCGCCGAAAT
CGCGATGATCAAGGTGCAGGCGCCGAACATGGCGCTGCAAATCATCGACGACGCGATTCAGGCGCATGGCGCCGGCGGCG
TCAGCGAGGATTTCGGGCTGGCCAAGGCCTATGCGCACCAGCGCACGCTGCGCATCGCCGACGGCCCCGACGAGGTGCAC
GCCCGCGCAATCGCGCGAATCGAGTTCGCGAAACATTCGCCCGCGGCCGACCCCGGTTTTTCGTCGGGCGACATCGGGGT
TTCGCGGTAA

Upstream 100 bases:

>100_bases
CGGCGTGGCCAAATGAGGTAATTTTCGGACCGCAGGACTTGGCAAGCCCGCCGAATCGGTCCAAAGGTTTACGTGAACGT
AAAGGGAAAGGACGCATCGC

Downstream 100 bases:

>100_bases
ACACGCCCCCCCCTTCCCGCTTGCGGGAGGGGGAATGATACGGAGCTATAAATGACCAAAGCCGCGATCCTGATCGAACC
GGGCAAGCCGCTCGTCATCG

Product: acyl-CoA dehydrogenase-like protein

Products: 2,3-dehydroacyl-CoA; reduced acceptor

Alternate protein names: NA

Number of amino acids: Translated: 429; Mature: 429

Protein sequence:

>429_residues
MDFDLTERQAHWQGRVREFIERKVRPAVPTYYEQDAAGDRWKVIQVVEDLKAEAKAAGIWNLFMPPRSAAHHHVDDTFEF
EGPGLTNLEYALCAEEMGRIGFASEVFNCSAPDTGNMEVFHRYGTRAQKDRWLKPLMNGEIRSAFLMTEPAVASSDATNI
ETRIERDGDDYIINGTKWWSSGAGDPRCKVAIVMGKTDFGAKRHAQQSMLVVPLDAPGVTIKRHLPVFGYDDAPHGHMEI
ELKDVRVNAEEAMLLGEGRGFEIAQGRLGPGRIHHCMRTIGVAEEALEKMCKRLQSRVAFGKTIAEQSIWEQRIARARID
IEMTRLLCLKAADMMDKIGNKSAAAEIAMIKVQAPNMALQIIDDAIQAHGAGGVSEDFGLAKAYAHQRTLRIADGPDEVH
ARAIARIEFAKHSPAADPGFSSGDIGVSR

Sequences:

>Translated_429_residues
MDFDLTERQAHWQGRVREFIERKVRPAVPTYYEQDAAGDRWKVIQVVEDLKAEAKAAGIWNLFMPPRSAAHHHVDDTFEF
EGPGLTNLEYALCAEEMGRIGFASEVFNCSAPDTGNMEVFHRYGTRAQKDRWLKPLMNGEIRSAFLMTEPAVASSDATNI
ETRIERDGDDYIINGTKWWSSGAGDPRCKVAIVMGKTDFGAKRHAQQSMLVVPLDAPGVTIKRHLPVFGYDDAPHGHMEI
ELKDVRVNAEEAMLLGEGRGFEIAQGRLGPGRIHHCMRTIGVAEEALEKMCKRLQSRVAFGKTIAEQSIWEQRIARARID
IEMTRLLCLKAADMMDKIGNKSAAAEIAMIKVQAPNMALQIIDDAIQAHGAGGVSEDFGLAKAYAHQRTLRIADGPDEVH
ARAIARIEFAKHSPAADPGFSSGDIGVSR
>Mature_429_residues
MDFDLTERQAHWQGRVREFIERKVRPAVPTYYEQDAAGDRWKVIQVVEDLKAEAKAAGIWNLFMPPRSAAHHHVDDTFEF
EGPGLTNLEYALCAEEMGRIGFASEVFNCSAPDTGNMEVFHRYGTRAQKDRWLKPLMNGEIRSAFLMTEPAVASSDATNI
ETRIERDGDDYIINGTKWWSSGAGDPRCKVAIVMGKTDFGAKRHAQQSMLVVPLDAPGVTIKRHLPVFGYDDAPHGHMEI
ELKDVRVNAEEAMLLGEGRGFEIAQGRLGPGRIHHCMRTIGVAEEALEKMCKRLQSRVAFGKTIAEQSIWEQRIARARID
IEMTRLLCLKAADMMDKIGNKSAAAEIAMIKVQAPNMALQIIDDAIQAHGAGGVSEDFGLAKAYAHQRTLRIADGPDEVH
ARAIARIEFAKHSPAADPGFSSGDIGVSR

Specific function: Unknown

COG id: COG1960

COG function: function code I; Acyl-CoA dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI211971008, Length=398, Percent_Identity=54.7738693467337, Blast_Score=429, Evalue=1e-120,
Organism=Homo sapiens, GI48976061, Length=398, Percent_Identity=54.7738693467337, Blast_Score=428, Evalue=1e-120,
Organism=Homo sapiens, GI38505218, Length=401, Percent_Identity=53.3665835411471, Blast_Score=420, Evalue=1e-117,
Organism=Homo sapiens, GI4557233, Length=328, Percent_Identity=29.8780487804878, Blast_Score=125, Evalue=8e-29,
Organism=Homo sapiens, GI4557231, Length=419, Percent_Identity=25.5369928400955, Blast_Score=115, Evalue=7e-26,
Organism=Homo sapiens, GI187960098, Length=419, Percent_Identity=25.5369928400955, Blast_Score=115, Evalue=1e-25,
Organism=Homo sapiens, GI4501859, Length=329, Percent_Identity=27.0516717325228, Blast_Score=111, Evalue=1e-24,
Organism=Homo sapiens, GI226958414, Length=332, Percent_Identity=26.8072289156627, Blast_Score=102, Evalue=7e-22,
Organism=Homo sapiens, GI226958412, Length=332, Percent_Identity=26.8072289156627, Blast_Score=102, Evalue=8e-22,
Organism=Homo sapiens, GI7656849, Length=284, Percent_Identity=27.8169014084507, Blast_Score=97, Evalue=3e-20,
Organism=Homo sapiens, GI21361497, Length=361, Percent_Identity=26.5927977839335, Blast_Score=96, Evalue=5e-20,
Organism=Homo sapiens, GI4501857, Length=305, Percent_Identity=27.8688524590164, Blast_Score=91, Evalue=2e-18,
Organism=Homo sapiens, GI4557235, Length=403, Percent_Identity=24.5657568238213, Blast_Score=89, Evalue=6e-18,
Organism=Homo sapiens, GI76496475, Length=403, Percent_Identity=24.5657568238213, Blast_Score=89, Evalue=7e-18,
Organism=Escherichia coli, GI87081958, Length=302, Percent_Identity=27.1523178807947, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI1786223, Length=407, Percent_Identity=23.3415233415233, Blast_Score=78, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17562446, Length=398, Percent_Identity=52.0100502512563, Blast_Score=383, Evalue=1e-107,
Organism=Caenorhabditis elegans, GI17534899, Length=417, Percent_Identity=28.0575539568345, Blast_Score=125, Evalue=4e-29,
Organism=Caenorhabditis elegans, GI17569725, Length=416, Percent_Identity=26.4423076923077, Blast_Score=121, Evalue=9e-28,
Organism=Caenorhabditis elegans, GI17505929, Length=397, Percent_Identity=25.1889168765743, Blast_Score=108, Evalue=7e-24,
Organism=Caenorhabditis elegans, GI17508101, Length=404, Percent_Identity=25.2475247524752, Blast_Score=106, Evalue=2e-23,
Organism=Caenorhabditis elegans, GI71985184, Length=410, Percent_Identity=27.8048780487805, Blast_Score=106, Evalue=2e-23,
Organism=Caenorhabditis elegans, GI17551932, Length=336, Percent_Identity=25.297619047619, Blast_Score=106, Evalue=3e-23,
Organism=Caenorhabditis elegans, GI17506239, Length=286, Percent_Identity=27.972027972028, Blast_Score=101, Evalue=9e-22,
Organism=Caenorhabditis elegans, GI17570075, Length=415, Percent_Identity=26.2650602409639, Blast_Score=100, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI71990804, Length=257, Percent_Identity=29.1828793774319, Blast_Score=96, Evalue=4e-20,
Organism=Caenorhabditis elegans, GI17538396, Length=330, Percent_Identity=24.5454545454545, Blast_Score=92, Evalue=7e-19,
Organism=Caenorhabditis elegans, GI17533517, Length=284, Percent_Identity=25.3521126760563, Blast_Score=90, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI71985192, Length=358, Percent_Identity=26.536312849162, Blast_Score=81, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI32563615, Length=191, Percent_Identity=29.3193717277487, Blast_Score=75, Evalue=5e-14,
Organism=Caenorhabditis elegans, GI17534353, Length=327, Percent_Identity=22.9357798165138, Blast_Score=73, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI71982178, Length=308, Percent_Identity=24.6753246753247, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24660351, Length=406, Percent_Identity=27.3399014778325, Blast_Score=117, Evalue=2e-26,
Organism=Drosophila melanogaster, GI21356377, Length=328, Percent_Identity=31.0975609756098, Blast_Score=114, Evalue=1e-25,
Organism=Drosophila melanogaster, GI24646207, Length=327, Percent_Identity=30.2752293577982, Blast_Score=113, Evalue=3e-25,
Organism=Drosophila melanogaster, GI281363737, Length=333, Percent_Identity=27.027027027027, Blast_Score=97, Evalue=3e-20,
Organism=Drosophila melanogaster, GI24666513, Length=328, Percent_Identity=25.9146341463415, Blast_Score=94, Evalue=3e-19,
Organism=Drosophila melanogaster, GI19920834, Length=327, Percent_Identity=24.4648318042813, Blast_Score=79, Evalue=8e-15,
Organism=Drosophila melanogaster, GI21355753, Length=329, Percent_Identity=23.7082066869301, Blast_Score=74, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: 1.3.99.3

Molecular weight: Translated: 47532; Mature: 47532

Theoretical pI: Translated: 6.46; Mature: 6.46

Prosite motif: PS00047 HISTONE_H4 ; PS00639 THIOL_PROTEASE_HIS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDFDLTERQAHWQGRVREFIERKVRPAVPTYYEQDAAGDRWKVIQVVEDLKAEAKAAGIW
CCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCEE
NLFMPPRSAAHHHVDDTFEFEGPGLTNLEYALCAEEMGRIGFASEVFNCSAPDTGNMEVF
EECCCCCCCCCCCCCCCEEECCCCCCCCHHHHHHHHHCCCCCHHHHCCCCCCCCCCHHHH
HRYGTRAQKDRWLKPLMNGEIRSAFLMTEPAVASSDATNIETRIERDGDDYIINGTKWWS
HHHCCCHHHHHHHHHHHCCCHHEEEEEECCCCCCCCCCCCHHEEECCCCCEEEECEEECC
SGAGDPRCKVAIVMGKTDFGAKRHAQQSMLVVPLDAPGVTIKRHLPVFGYDDAPHGHMEI
CCCCCCCEEEEEEECCCCCCHHHHCCCCEEEEEECCCCEEEEECCCEECCCCCCCCEEEE
ELKDVRVNAEEAMLLGEGRGFEIAQGRLGPGRIHHCMRTIGVAEEALEKMCKRLQSRVAF
EEEEEEECHHHEEEEECCCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GKTIAEQSIWEQRIARARIDIEMTRLLCLKAADMMDKIGNKSAAAEIAMIKVQAPNMALQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHEEEEEEEEECCCHHHH
IIDDAIQAHGAGGVSEDFGLAKAYAHQRTLRIADGPDEVHARAIARIEFAKHSPAADPGF
HHHHHHHHCCCCCCCHHHHHHHHHHHHCEEEECCCHHHHHHHHHHHHHHHCCCCCCCCCC
SSGDIGVSR
CCCCCCCCC
>Mature Secondary Structure
MDFDLTERQAHWQGRVREFIERKVRPAVPTYYEQDAAGDRWKVIQVVEDLKAEAKAAGIW
CCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCEE
NLFMPPRSAAHHHVDDTFEFEGPGLTNLEYALCAEEMGRIGFASEVFNCSAPDTGNMEVF
EECCCCCCCCCCCCCCCEEECCCCCCCCHHHHHHHHHCCCCCHHHHCCCCCCCCCCHHHH
HRYGTRAQKDRWLKPLMNGEIRSAFLMTEPAVASSDATNIETRIERDGDDYIINGTKWWS
HHHCCCHHHHHHHHHHHCCCHHEEEEEECCCCCCCCCCCCHHEEECCCCCEEEECEEECC
SGAGDPRCKVAIVMGKTDFGAKRHAQQSMLVVPLDAPGVTIKRHLPVFGYDDAPHGHMEI
CCCCCCCEEEEEEECCCCCCHHHHCCCCEEEEEECCCCEEEEECCCEECCCCCCCCEEEE
ELKDVRVNAEEAMLLGEGRGFEIAQGRLGPGRIHHCMRTIGVAEEALEKMCKRLQSRVAF
EEEEEEECHHHEEEEECCCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GKTIAEQSIWEQRIARARIDIEMTRLLCLKAADMMDKIGNKSAAAEIAMIKVQAPNMALQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHEEEEEEEEECCCHHHH
IIDDAIQAHGAGGVSEDFGLAKAYAHQRTLRIADGPDEVHARAIARIEFAKHSPAADPGF
HHHHHHHHCCCCCCCHHHHHHHHHHHHCEEEECCCHHHHHHHHHHHHHHHCCCCCCCCCC
SSGDIGVSR
CCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: acyl-CoA; acceptor

Specific reaction: acyl-CoA + acceptor = 2,3-dehydroacyl-CoA + reduced acceptor

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9387222; 9384377 [H]