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The map label for this gene is exuR [H]

Identifier: 103488509

GI number: 103488509

Start: 3180084

End: 3181139

Strand: Reverse

Name: exuR [H]

Synonym: Sala_3033

Alternate gene names: 103488509

Gene position: 3181139-3180084 (Counterclockwise)

Preceding gene: 103488514

Following gene: 103488500

Centisome position: 95.1

GC content: 66.29

Gene sequence:

>1056_bases
ATGGCGGCACAGACCAGGGGGCCGGGGGGCAGGCAGCCGACAATCAACGACGTCGCCGCGCTTGCGGGTGTGTCCAAGAA
AACGGTAAGCCGGGTCATCAACCGGTCGGAGTTCCTGACCGAAAAGACGCGCGCCGCGGTGGAAAAGGCGATCGAGCAAC
TGGGGTTCGTCCCCAATCCGCAAGCGCGTGCGCTCGCCTTTCGCCGCAACTTCCTGATCGCGCTGCTCCACGACAATCCG
AACGCACAGACGGTGCTCAATTTCCAGCGCGGCGTGCTCGACGCGATCAAGGACAGCGATCTGGCGCTGCTCGTCCGCCC
GGTCGATCGCGGGTCGGACAAACTGCTCGACGATGTGCGCACCTTCCTCGAAAAACAGCGTCCGATTGGCGCGATGCTGT
TGCCGCCGATTTCGGAGAATGACGAACTCGCGGCGCTTTGTGAGGATCTGGGCGTGCGTTATGTGCGTATCGGCTCGGCG
CCGCTCGACGATGCCAAACATTGCATCTCGTCGAATGATCGTGAAGTGGTGGCGGCGGCGGTGCGCGGGCTGATTGCGCT
GGGGCACCGCCGCATCGGCTTCGTGCGCGGCCCGGCCGGTTTCCGCTCCGCCGCCGAGCGCGAGAAGGGCTTTTTGGAGG
CGCTCGCCGAAGCGGGGCTCACGCTTCCGCCCGAGCTCAATGCGCCGGGTAACTACCGCTATGCCGCCGGAATCGAGGCG
GGCGAGGCGCTGCTCGCGCGCGCCGATCCGCCGACGGCGATCTTCTGCTCGAACGACGAAATGGCGGCGGGGGTGCTGAG
CGTCGCGCATGGCAAGGGAATCAAGGTGCCCGCCGAACTGTCGATCATCGGCTTCGACGACAGCCCGACCGCAACGCATA
TCTGGCCCGCGCTCAGCACGGTGCGCTGGCCGATCCGCGAAATGGGCGCGCGCGCCGCGCAGATCCTCGTTCCCGATTTT
CTCGGCCCCGGCGCGAAGGTCGATGACGAAGACAATGTGCTGCCCTCAACATTGGTCGAGCGGCAGTCGGTCGCGCCCCC
GCCCGACAGGCTCTGA

Upstream 100 bases:

>100_bases
GCCGCCTGCCCGTTGCGACGGTTGATTTTGGCGCGGCGAGCGCCCATCACAACGCCGGAAAGGCGGGACATGGCCGAGGC
CCGCAAAGGGAAAAGCGCAT

Downstream 100 bases:

>100_bases
GCGCCGAGCCCTCGGCTTCTGGCGTCGGGCCGTATCGACATTCAGCCCTGGCTGGCGACCTGCAAATGGCGGCGTTCCGC
GCTTCCGCTGCTCACGCGCC

Product: LacI family transcription regulator

Products: NA

Alternate protein names: Probable galacturonate locus repressor [H]

Number of amino acids: Translated: 351; Mature: 350

Protein sequence:

>351_residues
MAAQTRGPGGRQPTINDVAALAGVSKKTVSRVINRSEFLTEKTRAAVEKAIEQLGFVPNPQARALAFRRNFLIALLHDNP
NAQTVLNFQRGVLDAIKDSDLALLVRPVDRGSDKLLDDVRTFLEKQRPIGAMLLPPISENDELAALCEDLGVRYVRIGSA
PLDDAKHCISSNDREVVAAAVRGLIALGHRRIGFVRGPAGFRSAAEREKGFLEALAEAGLTLPPELNAPGNYRYAAGIEA
GEALLARADPPTAIFCSNDEMAAGVLSVAHGKGIKVPAELSIIGFDDSPTATHIWPALSTVRWPIREMGARAAQILVPDF
LGPGAKVDDEDNVLPSTLVERQSVAPPPDRL

Sequences:

>Translated_351_residues
MAAQTRGPGGRQPTINDVAALAGVSKKTVSRVINRSEFLTEKTRAAVEKAIEQLGFVPNPQARALAFRRNFLIALLHDNP
NAQTVLNFQRGVLDAIKDSDLALLVRPVDRGSDKLLDDVRTFLEKQRPIGAMLLPPISENDELAALCEDLGVRYVRIGSA
PLDDAKHCISSNDREVVAAAVRGLIALGHRRIGFVRGPAGFRSAAEREKGFLEALAEAGLTLPPELNAPGNYRYAAGIEA
GEALLARADPPTAIFCSNDEMAAGVLSVAHGKGIKVPAELSIIGFDDSPTATHIWPALSTVRWPIREMGARAAQILVPDF
LGPGAKVDDEDNVLPSTLVERQSVAPPPDRL
>Mature_350_residues
AAQTRGPGGRQPTINDVAALAGVSKKTVSRVINRSEFLTEKTRAAVEKAIEQLGFVPNPQARALAFRRNFLIALLHDNPN
AQTVLNFQRGVLDAIKDSDLALLVRPVDRGSDKLLDDVRTFLEKQRPIGAMLLPPISENDELAALCEDLGVRYVRIGSAP
LDDAKHCISSNDREVVAAAVRGLIALGHRRIGFVRGPAGFRSAAEREKGFLEALAEAGLTLPPELNAPGNYRYAAGIEAG
EALLARADPPTAIFCSNDEMAAGVLSVAHGKGIKVPAELSIIGFDDSPTATHIWPALSTVRWPIREMGARAAQILVPDFL
GPGAKVDDEDNVLPSTLVERQSVAPPPDRL

Specific function: Transcriptional repressor for the exu locus which is required for galacturonate utilization (Probable) [H]

COG id: COG1609

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lacI-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787948, Length=352, Percent_Identity=31.8181818181818, Blast_Score=141, Evalue=5e-35,
Organism=Escherichia coli, GI1789202, Length=335, Percent_Identity=33.7313432835821, Blast_Score=140, Evalue=8e-35,
Organism=Escherichia coli, GI1790194, Length=310, Percent_Identity=30, Blast_Score=139, Evalue=3e-34,
Organism=Escherichia coli, GI1788474, Length=349, Percent_Identity=32.6647564469914, Blast_Score=135, Evalue=3e-33,
Organism=Escherichia coli, GI1789068, Length=305, Percent_Identity=29.8360655737705, Blast_Score=131, Evalue=7e-32,
Organism=Escherichia coli, GI1786540, Length=341, Percent_Identity=27.2727272727273, Blast_Score=122, Evalue=4e-29,
Organism=Escherichia coli, GI1790369, Length=353, Percent_Identity=29.4617563739377, Blast_Score=121, Evalue=7e-29,
Organism=Escherichia coli, GI1787580, Length=315, Percent_Identity=25.3968253968254, Blast_Score=101, Evalue=6e-23,
Organism=Escherichia coli, GI48994940, Length=318, Percent_Identity=24.5283018867925, Blast_Score=85, Evalue=6e-18,
Organism=Escherichia coli, GI1789456, Length=310, Percent_Identity=25.1612903225806, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1787906, Length=314, Percent_Identity=26.4331210191083, Blast_Score=72, Evalue=6e-14,
Organism=Escherichia coli, GI1790689, Length=338, Percent_Identity=24.5562130177515, Blast_Score=68, Evalue=9e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000843
- InterPro:   IPR010982
- InterPro:   IPR001761 [H]

Pfam domain/function: PF00356 LacI; PF00532 Peripla_BP_1 [H]

EC number: NA

Molecular weight: Translated: 37599; Mature: 37468

Theoretical pI: Translated: 6.38; Mature: 6.38

Prosite motif: PS00356 HTH_LACI_1 ; PS50932 HTH_LACI_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAAQTRGPGGRQPTINDVAALAGVSKKTVSRVINRSEFLTEKTRAAVEKAIEQLGFVPNP
CCCCCCCCCCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
QARALAFRRNFLIALLHDNPNAQTVLNFQRGVLDAIKDSDLALLVRPVDRGSDKLLDDVR
HHHHHHEECCEEEEEEECCCCCHHHHHHHHHHHHHHCCCCEEEEEEECCCCCHHHHHHHH
TFLEKQRPIGAMLLPPISENDELAALCEDLGVRYVRIGSAPLDDAKHCISSNDREVVAAA
HHHHHCCCCCEEEECCCCCCCHHHHHHHHHCCEEEEECCCCCHHHHHHHCCCCHHHHHHH
VRGLIALGHRRIGFVRGPAGFRSAAEREKGFLEALAEAGLTLPPELNAPGNYRYAAGIEA
HHHHHHHCCHHEEEEECCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEECCCCC
GEALLARADPPTAIFCSNDEMAAGVLSVAHGKGIKVPAELSIIGFDDSPTATHIWPALST
CHHHEECCCCCCEEEECCCCHHHHHHHHHCCCCCCCCCEEEEEECCCCCCCHHHHHHHHH
VRWPIREMGARAAQILVPDFLGPGAKVDDEDNVLPSTLVERQSVAPPPDRL
HHCCHHHHCCHHHHHCCHHHCCCCCCCCCCCCCCHHHHHHHHCCCCCCCCC
>Mature Secondary Structure 
AAQTRGPGGRQPTINDVAALAGVSKKTVSRVINRSEFLTEKTRAAVEKAIEQLGFVPNP
CCCCCCCCCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
QARALAFRRNFLIALLHDNPNAQTVLNFQRGVLDAIKDSDLALLVRPVDRGSDKLLDDVR
HHHHHHEECCEEEEEEECCCCCHHHHHHHHHHHHHHCCCCEEEEEEECCCCCHHHHHHHH
TFLEKQRPIGAMLLPPISENDELAALCEDLGVRYVRIGSAPLDDAKHCISSNDREVVAAA
HHHHHCCCCCEEEECCCCCCCHHHHHHHHHCCEEEEECCCCCHHHHHHHCCCCHHHHHHH
VRGLIALGHRRIGFVRGPAGFRSAAEREKGFLEALAEAGLTLPPELNAPGNYRYAAGIEA
HHHHHHHCCHHEEEEECCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEECCCCC
GEALLARADPPTAIFCSNDEMAAGVLSVAHGKGIKVPAELSIIGFDDSPTATHIWPALST
CHHHEECCCCCCEEEECCCCHHHHHHHHHCCCCCCCCCEEEEEECCCCCCCHHHHHHHHH
VRWPIREMGARAAQILVPDFLGPGAKVDDEDNVLPSTLVERQSVAPPPDRL
HHCCHHHHCCHHHHHCCHHHCCCCCCCCCCCCCCHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9579062; 9384377 [H]