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The map label for this gene is pheS [H]

Identifier: 103488259

GI number: 103488259

Start: 2941893

End: 2942990

Strand: Direct

Name: pheS [H]

Synonym: Sala_2782

Alternate gene names: 103488259

Gene position: 2941893-2942990 (Clockwise)

Preceding gene: 103488258

Following gene: 103488260

Centisome position: 87.94

GC content: 66.76

Gene sequence:

>1098_bases
ATGATGAGCGACATGGAAGCCATCGAGGCGCAACTGCGGCGCGACATCGACGCCGCGGCCGACGCCGGAGCGATCGAGGC
GGTGCGCGTCGCGGCACTCGGCAAGGCGGGTCGCATCACCGCGCTCCTGAAAACGCTGGGCGGCATGACCCCCGACGAAC
GGCAGGCGAAGGGGCCCGCGATCCACGCGCTGCGCGAGAGCGTGACCGCCGCGATCGCGGAGCGCAAGGCGGCGATCGAG
GCCGCCGAACTCGAGGCGCGGCTCGCGACCGAGAAGCTGGACATGACCCTGCCCGCCGATGCCGCCCCCCGCGGCAGCGT
CCATCCGGTCGCCCAGGTGATGGACGAACTCGCCGAAATCTTCGCCGACATGGGATTTGCGGTGGCGACGGGGCCGGAGA
TCGAGGACGACTGGCACAATTTCACCGCGCTCAACATTCCCGAAACGCACCCCGCGCGCGCGATGCACGACACCTTCTAT
TTCCCGAACAGCAATGCCGAAAGCCACGCGATGCTGCTGCGCACGCACACCTCGCCGGTGCAGATCCGCACGATGATGAC
GCAGGAACCGCCGATCCGCATCATCGCCCCCGGCCGCGTCTATCGCAGCGACAGCGACGCGACGCACACGCCGATGTTCC
ACCAGGTCGAAGGGCTCGTCATCGACCGCGGCATCCATATGGGGCACCTGAAATGGACGCTCGAGACGTTCCTGAAAGCC
TATTTCGAGCGCGACGACATCGTGCTGCGGCTACGCCCCAGCTATTTCCCCTTCACCGAACCGTCGGCCGAGGTCGATGT
CGGTTACAAGCAGGAAAAGGGGCGCCGGATCGTCGGCGGTAACGGCGATGATGAGGGCCATGCGTGGATGGAGCTGCTGG
GCAGCGGCATGGTGAACCGCCGCGTGATCGCCAGTTGCGGGCTCGATCCCGACGCGTGGCAGGGCTTTGCCTTCGGGGTC
GGGGTCGACCGGCTCGCGATGCTCAAATATGGCATGGACGATTTGCGCGCCTTCTTCGACGGCGACCTCCGCTGGCTCGC
GCATTACGGGTTCGGCGCGCTGAGCGTCCCGACTTTGAGCGGGGGGATTTCGGCATGA

Upstream 100 bases:

>100_bases
GGTGCAAGCGGCTGCAAACGGACGCGCGGGCAGCCGCCTATCCTTGCAATCGATGTGGCATTAGGCCGGCCGCGACAGCG
CCGCCGGAACGGGACGAATG

Downstream 100 bases:

>100_bases
AACTGACCCTCGACTGGTTAAAAGACCACCTCGACGGCGATTTCACCGTCGAAGATGTCGTCGCCACCCTCAACCGCATC
GGCCACGAAGTCGAAGGCGT

Product: phenylalanyl-tRNA synthetase subunit alpha

Products: NA

Alternate protein names: Phenylalanine--tRNA ligase alpha chain; PheRS [H]

Number of amino acids: Translated: 365; Mature: 365

Protein sequence:

>365_residues
MMSDMEAIEAQLRRDIDAAADAGAIEAVRVAALGKAGRITALLKTLGGMTPDERQAKGPAIHALRESVTAAIAERKAAIE
AAELEARLATEKLDMTLPADAAPRGSVHPVAQVMDELAEIFADMGFAVATGPEIEDDWHNFTALNIPETHPARAMHDTFY
FPNSNAESHAMLLRTHTSPVQIRTMMTQEPPIRIIAPGRVYRSDSDATHTPMFHQVEGLVIDRGIHMGHLKWTLETFLKA
YFERDDIVLRLRPSYFPFTEPSAEVDVGYKQEKGRRIVGGNGDDEGHAWMELLGSGMVNRRVIASCGLDPDAWQGFAFGV
GVDRLAMLKYGMDDLRAFFDGDLRWLAHYGFGALSVPTLSGGISA

Sequences:

>Translated_365_residues
MMSDMEAIEAQLRRDIDAAADAGAIEAVRVAALGKAGRITALLKTLGGMTPDERQAKGPAIHALRESVTAAIAERKAAIE
AAELEARLATEKLDMTLPADAAPRGSVHPVAQVMDELAEIFADMGFAVATGPEIEDDWHNFTALNIPETHPARAMHDTFY
FPNSNAESHAMLLRTHTSPVQIRTMMTQEPPIRIIAPGRVYRSDSDATHTPMFHQVEGLVIDRGIHMGHLKWTLETFLKA
YFERDDIVLRLRPSYFPFTEPSAEVDVGYKQEKGRRIVGGNGDDEGHAWMELLGSGMVNRRVIASCGLDPDAWQGFAFGV
GVDRLAMLKYGMDDLRAFFDGDLRWLAHYGFGALSVPTLSGGISA
>Mature_365_residues
MMSDMEAIEAQLRRDIDAAADAGAIEAVRVAALGKAGRITALLKTLGGMTPDERQAKGPAIHALRESVTAAIAERKAAIE
AAELEARLATEKLDMTLPADAAPRGSVHPVAQVMDELAEIFADMGFAVATGPEIEDDWHNFTALNIPETHPARAMHDTFY
FPNSNAESHAMLLRTHTSPVQIRTMMTQEPPIRIIAPGRVYRSDSDATHTPMFHQVEGLVIDRGIHMGHLKWTLETFLKA
YFERDDIVLRLRPSYFPFTEPSAEVDVGYKQEKGRRIVGGNGDDEGHAWMELLGSGMVNRRVIASCGLDPDAWQGFAFGV
GVDRLAMLKYGMDDLRAFFDGDLRWLAHYGFGALSVPTLSGGISA

Specific function: Unknown

COG id: COG0016

COG function: function code J; Phenylalanyl-tRNA synthetase alpha subunit

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha chain type 1 subfamily [H]

Homologues:

Organism=Homo sapiens, GI4758340, Length=273, Percent_Identity=30.7692307692308, Blast_Score=120, Evalue=2e-27,
Organism=Homo sapiens, GI5729820, Length=254, Percent_Identity=28.3464566929134, Blast_Score=96, Evalue=7e-20,
Organism=Escherichia coli, GI1788007, Length=348, Percent_Identity=51.1494252873563, Blast_Score=356, Evalue=1e-99,
Organism=Caenorhabditis elegans, GI32563657, Length=274, Percent_Identity=30.6569343065693, Blast_Score=122, Evalue=4e-28,
Organism=Caenorhabditis elegans, GI17508957, Length=274, Percent_Identity=30.6569343065693, Blast_Score=121, Evalue=5e-28,
Organism=Caenorhabditis elegans, GI32566635, Length=260, Percent_Identity=30.3846153846154, Blast_Score=99, Evalue=5e-21,
Organism=Saccharomyces cerevisiae, GI6321087, Length=275, Percent_Identity=29.4545454545455, Blast_Score=124, Evalue=2e-29,
Organism=Saccharomyces cerevisiae, GI6325304, Length=321, Percent_Identity=24.2990654205607, Blast_Score=86, Evalue=9e-18,
Organism=Drosophila melanogaster, GI18858079, Length=395, Percent_Identity=28.3544303797468, Blast_Score=115, Evalue=5e-26,

Paralogues:

None

Copy number: 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006195
- InterPro:   IPR004529
- InterPro:   IPR004188
- InterPro:   IPR022911
- InterPro:   IPR002319
- InterPro:   IPR010978 [H]

Pfam domain/function: PF02912 Phe_tRNA-synt_N; PF01409 tRNA-synt_2d [H]

EC number: =6.1.1.20 [H]

Molecular weight: Translated: 39940; Mature: 39940

Theoretical pI: Translated: 5.14; Mature: 5.14

Prosite motif: PS50862 AA_TRNA_LIGASE_II

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
4.7 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
4.7 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMSDMEAIEAQLRRDIDAAADAGAIEAVRVAALGKAGRITALLKTLGGMTPDERQAKGPA
CCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCHHHHHHHHHCCCCCCHHHCCCHH
IHALRESVTAAIAERKAAIEAAELEARLATEKLDMTLPADAAPRGSVHPVAQVMDELAEI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEECCCCCCCCCCCCHHHHHHHHHHHH
FADMGFAVATGPEIEDDWHNFTALNIPETHPARAMHDTFYFPNSNAESHAMLLRTHTSPV
HHHCCCEEECCCCCCCCCCCEEEECCCCCCCCHHHHHEEECCCCCCCCCEEEEEECCCCE
QIRTMMTQEPPIRIIAPGRVYRSDSDATHTPMFHQVEGLVIDRGIHMGHLKWTLETFLKA
EEEEEECCCCCEEEEECCEEEECCCCCCCCCHHHHHCCEEEECCCEECHHHHHHHHHHHH
YFERDDIVLRLRPSYFPFTEPSAEVDVGYKQEKGRRIVGGNGDDEGHAWMELLGSGMVNR
HHCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCEEECCCCCCCHHHHHHHHHCCCCCC
RVIASCGLDPDAWQGFAFGVGVDRLAMLKYGMDDLRAFFDGDLRWLAHYGFGALSVPTLS
HHHHHCCCCHHHCCCEEECCCHHHHHHHHHCHHHHHHHHCCCHHHHHHCCCCCEECCCCC
GGISA
CCCCC
>Mature Secondary Structure
MMSDMEAIEAQLRRDIDAAADAGAIEAVRVAALGKAGRITALLKTLGGMTPDERQAKGPA
CCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCHHHHHHHHHCCCCCCHHHCCCHH
IHALRESVTAAIAERKAAIEAAELEARLATEKLDMTLPADAAPRGSVHPVAQVMDELAEI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEECCCCCCCCCCCCHHHHHHHHHHHH
FADMGFAVATGPEIEDDWHNFTALNIPETHPARAMHDTFYFPNSNAESHAMLLRTHTSPV
HHHCCCEEECCCCCCCCCCCEEEECCCCCCCCHHHHHEEECCCCCCCCCEEEEEECCCCE
QIRTMMTQEPPIRIIAPGRVYRSDSDATHTPMFHQVEGLVIDRGIHMGHLKWTLETFLKA
EEEEEECCCCCEEEEECCEEEECCCCCCCCCHHHHHCCEEEECCCEECHHHHHHHHHHHH
YFERDDIVLRLRPSYFPFTEPSAEVDVGYKQEKGRRIVGGNGDDEGHAWMELLGSGMVNR
HHCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCEEECCCCCCCHHHHHHHHHCCCCCC
RVIASCGLDPDAWQGFAFGVGVDRLAMLKYGMDDLRAFFDGDLRWLAHYGFGALSVPTLS
HHHHHCCCCHHHCCCEEECCCHHHHHHHHHCHHHHHHHHCCCHHHHHHCCCCCEECCCCC
GGISA
CCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA