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The map label for this gene is nccB [H]

Identifier: 103488056

GI number: 103488056

Start: 2718261

End: 2719418

Strand: Direct

Name: nccB [H]

Synonym: Sala_2578

Alternate gene names: 103488056

Gene position: 2718261-2719418 (Clockwise)

Preceding gene: 103488055

Following gene: 103488057

Centisome position: 81.26

GC content: 66.06

Gene sequence:

>1158_bases
ATGATCACACAGGACAAACGCCTTCTTGGCGGCGTGGCTGGCGCGGTGCTGCTCGCGGCCGTCGGCGGCTTCTCGGTTGC
CCGCTGCACCGCAGATCCGGCTGCCGAGACCCGAAATGCCGATAAGGCAGAAGAAGCGGAAGCTCACACTGATAACCTTG
CGATCACTGCCGATGCGATCCGTGCAGCAGAGATCGCCGTAGAAGCGGTGCGGGCTGGCGGGCTCGGATCCGAAATCCTC
GCGCAGGGCACGGTCACCGCGACACCGGCGGGTGAAGCGATCGTCACGGCCCGCGCCGGCGGCGCCGTCACGCGCGTTCT
CAAGCGCCTGGGCGATCCGGTACGTGCCGGAGAGACGCTGGCCATCGTGCAAAGCCGAGACGCCGCCCAGATCGCCGCGG
ACCGAACGGCAGCCGAGGCGCGCTCGGTTCTGGCCCAGCGCACACTAGCTCGGGAGCGCCATCTCTACGAGCAGAAGGTC
ACCGCCCGTGCCGATTATGAGCAGGCGCAGGCAGAGGCCGCAGCCGCTACGGCCGAAGCGCGAAGAGCCCAGGTTGCGGC
CAGTGCTGCGAACGTCACACGCGATGGCAGCGGTGCGATCGTGGCCAGCCCGATCTCCGGGCGGGTGACGGCGGAAAGCG
TCAGCCTTGGCGCGTTCGTGCAACCGGAGACGGAGTTGTTCCGCATTGCGGACCCGTCCAAAGTACAGGTCGAGGCTGCC
GTCGGTCCAATTGACGCACAGCGGCTTGCTCCCGGCGACCGGGCCATCGTCGAGCTGCCCGATGGCCGAACTCTAGACGC
TCGTGTGCGTGCCGTTACGCCTGGTCTCGGCGGCGAGACCCGTTCGGCCACGGCTGTGCTCGATGTCCAGGCAAGTCTGC
AGCCTGGGCTTGCCGTACGCGTCCGGCTGCTGCCGAGCCGTGGTGAAGTGTCGGATGCAATCGTCATATCGGAGGATGCG
CTTCAATCCCTCGAAGGACGAGATATTGTTTTCGTGCGAACCAATCAGGGCTTCCGCGCGCAAAAGGTGACAATCGGCCG
CCGCAGCGCCGGCCGCGTCGAGATTATCTCAGGCCTGAAGGCAGGCGAGATGATCGCAACCCAAAATGCATTCCTGCTCA
AGGCCGAGCTCGGCAAGGGCGCGGGCGAGGAGGAATAA

Upstream 100 bases:

>100_bases
CAACGGTCGGCGCGATAGCGCTTTCCTCAGCCTTTGCCTCACGGTCCGCAGCGGCGCGCAAGCTGCTGCAGCCAGCCCAC
ACGATATTCGGAGATGTTGA

Downstream 100 bases:

>100_bases
ACCGTGATTGCAAGTCTCATTGCGCTCGCCGTCCGCGCACGCTGGGCGATCCTGTTCATCTTCCTCGCGGTCGCCGGCCT
CGGCATCTGGCAGCTGACGA

Product: secretion protein HlyD

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 385; Mature: 385

Protein sequence:

>385_residues
MITQDKRLLGGVAGAVLLAAVGGFSVARCTADPAAETRNADKAEEAEAHTDNLAITADAIRAAEIAVEAVRAGGLGSEIL
AQGTVTATPAGEAIVTARAGGAVTRVLKRLGDPVRAGETLAIVQSRDAAQIAADRTAAEARSVLAQRTLARERHLYEQKV
TARADYEQAQAEAAAATAEARRAQVAASAANVTRDGSGAIVASPISGRVTAESVSLGAFVQPETELFRIADPSKVQVEAA
VGPIDAQRLAPGDRAIVELPDGRTLDARVRAVTPGLGGETRSATAVLDVQASLQPGLAVRVRLLPSRGEVSDAIVISEDA
LQSLEGRDIVFVRTNQGFRAQKVTIGRRSAGRVEIISGLKAGEMIATQNAFLLKAELGKGAGEEE

Sequences:

>Translated_385_residues
MITQDKRLLGGVAGAVLLAAVGGFSVARCTADPAAETRNADKAEEAEAHTDNLAITADAIRAAEIAVEAVRAGGLGSEIL
AQGTVTATPAGEAIVTARAGGAVTRVLKRLGDPVRAGETLAIVQSRDAAQIAADRTAAEARSVLAQRTLARERHLYEQKV
TARADYEQAQAEAAAATAEARRAQVAASAANVTRDGSGAIVASPISGRVTAESVSLGAFVQPETELFRIADPSKVQVEAA
VGPIDAQRLAPGDRAIVELPDGRTLDARVRAVTPGLGGETRSATAVLDVQASLQPGLAVRVRLLPSRGEVSDAIVISEDA
LQSLEGRDIVFVRTNQGFRAQKVTIGRRSAGRVEIISGLKAGEMIATQNAFLLKAELGKGAGEEE
>Mature_385_residues
MITQDKRLLGGVAGAVLLAAVGGFSVARCTADPAAETRNADKAEEAEAHTDNLAITADAIRAAEIAVEAVRAGGLGSEIL
AQGTVTATPAGEAIVTARAGGAVTRVLKRLGDPVRAGETLAIVQSRDAAQIAADRTAAEARSVLAQRTLARERHLYEQKV
TARADYEQAQAEAAAATAEARRAQVAASAANVTRDGSGAIVASPISGRVTAESVSLGAFVQPETELFRIADPSKVQVEAA
VGPIDAQRLAPGDRAIVELPDGRTLDARVRAVTPGLGGETRSATAVLDVQASLQPGLAVRVRLLPSRGEVSDAIVISEDA
LQSLEGRDIVFVRTNQGFRAQKVTIGRRSAGRVEIISGLKAGEMIATQNAFLLKAELGKGAGEEE

Specific function: Component of the NCC cation efflux system that confers resistance to nickel, cobalt and cadmium [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005695
- InterPro:   IPR006143 [H]

Pfam domain/function: PF00529 HlyD [H]

EC number: NA

Molecular weight: Translated: 39696; Mature: 39696

Theoretical pI: Translated: 5.37; Mature: 5.37

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
0.5 %Met     (Translated Protein)
0.8 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
0.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MITQDKRLLGGVAGAVLLAAVGGFSVARCTADPAAETRNADKAEEAEAHTDNLAITADAI
CCCCCHHHHHHHHHHHHHHHHCCCEEEEECCCCCHHCCCCCCHHHHHCCCCCEEEEHHHH
RAAEIAVEAVRAGGLGSEILAQGTVTATPAGEAIVTARAGGAVTRVLKRLGDPVRAGETL
HHHHHHHHHHHCCCCCHHHHHCCCEEECCCCCEEEEECCCHHHHHHHHHCCCCCCCCCEE
AIVQSRDAAQIAADRTAAEARSVLAQRTLARERHLYEQKVTARADYEQAQAEAAAATAEA
EEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHH
RRAQVAASAANVTRDGSGAIVASPISGRVTAESVSLGAFVQPETELFRIADPSKVQVEAA
HHHHHHHHHHCCCCCCCCCEEECCCCCCEEEEEEEECEEECCCCCEEEECCCCCEEEEEE
VGPIDAQRLAPGDRAIVELPDGRTLDARVRAVTPGLGGETRSATAVLDVQASLQPGLAVR
CCCCCHHHCCCCCCEEEECCCCCEECCEEEEECCCCCCCCCCCEEEEEEECCCCCCEEEE
VRLLPSRGEVSDAIVISEDALQSLEGRDIVFVRTNQGFRAQKVTIGRRSAGRVEIISGLK
EEEECCCCCCCCEEEEEHHHHHHCCCCEEEEEECCCCCEEEEEEECCCCCCCEEEECCCC
AGEMIATQNAFLLKAELGKGAGEEE
CCCEEECCCEEEEEEECCCCCCCCC
>Mature Secondary Structure
MITQDKRLLGGVAGAVLLAAVGGFSVARCTADPAAETRNADKAEEAEAHTDNLAITADAI
CCCCCHHHHHHHHHHHHHHHHCCCEEEEECCCCCHHCCCCCCHHHHHCCCCCEEEEHHHH
RAAEIAVEAVRAGGLGSEILAQGTVTATPAGEAIVTARAGGAVTRVLKRLGDPVRAGETL
HHHHHHHHHHHCCCCCHHHHHCCCEEECCCCCEEEEECCCHHHHHHHHHCCCCCCCCCEE
AIVQSRDAAQIAADRTAAEARSVLAQRTLARERHLYEQKVTARADYEQAQAEAAAATAEA
EEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHH
RRAQVAASAANVTRDGSGAIVASPISGRVTAESVSLGAFVQPETELFRIADPSKVQVEAA
HHHHHHHHHHCCCCCCCCCEEECCCCCCEEEEEEEECEEECCCCCEEEECCCCCEEEEEE
VGPIDAQRLAPGDRAIVELPDGRTLDARVRAVTPGLGGETRSATAVLDVQASLQPGLAVR
CCCCCHHHCCCCCCEEEECCCCCEECCEEEEECCCCCCCCCCCEEEEEEECCCCCCEEEE
VRLLPSRGEVSDAIVISEDALQSLEGRDIVFVRTNQGFRAQKVTIGRRSAGRVEIISGLK
EEEECCCCCCCCEEEEEHHHHHHCCCCEEEEEECCCCCEEEEEEECCCCCCCEEEECCCC
AGEMIATQNAFLLKAELGKGAGEEE
CCCEEECCCEEEEEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7961470 [H]