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The map label for this gene is czcC [H]

Identifier: 103488045

GI number: 103488045

Start: 2704996

End: 2706297

Strand: Direct

Name: czcC [H]

Synonym: Sala_2567

Alternate gene names: 103488045

Gene position: 2704996-2706297 (Clockwise)

Preceding gene: 103488044

Following gene: 103488046

Centisome position: 80.86

GC content: 69.51

Gene sequence:

>1302_bases
ATGCACCGATTGCTCGCGGCCCTGCTGGCCGCGACCGCTTGCGCGACCATCGCGCAGGCCCAAACCTCGTCGCCGGTTGA
TACCGGGGCCGCTCAGCCACAAAGCACGTCGCCCGCCCTAATGGGCCCGGCTTTCACGGTCGATCGCGCACTCGAGCTTG
CCGGCGTCGTCTCGCCAGCGCTCGAAGCCGCCTCGGCGGACATTCGCGCTGCCGAAGCGGGACGGCGCGTCGCGGGGCTC
CGGCCCAATCCCAGCGTCACGGTCGAAGCTGAAAACGTCGCTGGTTCCGGCCCGTACCGTGGCACGCAGAGCCTGGAAGC
GACCACATCGCTTACGCTGCCGATCGAACTCGGCGGCAAGCGATCGGCTCGGATCGCCGTCGCGGACGCTCGAACCGACC
GGGCCACCATACAGGCCACGATCGCACAAGCCGATCTCCGGCTGAACGTCATTCGCGCCTACGCGGAGGCCGCCTCGGCG
GAACGTCGGCTCATCACCGCCCACGATCAGGCCCGTATCGCAAATGAAACCCTGCGCGCCGCGCAGGTCCGCGTGCAGGC
GGGCCGCGCGTCGCCGATCGAAGCTGAGCGAGCGAACGTAGCACGGGTCAATGCCGACGCTGCGCTAACGCGGGAAGAAC
GGGCTGTCGAAGTCGCGCGGTTCACCCTGTCGCGTATTATAGGCCAACCCATCGCGGGGCCGCTCGACACGGACTGGTTC
TCCCGCGTGCCCGCGACCTATGGCCCCCTCCGGCCAATCGACAGCACGGGCACGCTCATGATGGCGGCGGCCAATGCCGA
CTTCGCTATCGCCGACGCCGGCGTGCGCCTCGCGCGCTCGCAGCGCGTGCCCGACCTGACGCTTGGGGCCGGCGCGCGCC
GGCTCGAGCAGACCAATGACACGGCGGCGATTTTCAGCCTGTCGATCCCGATCCCGATGTTCAACAACGGCCGGGCCGCG
TTGAGCCAAGCTACCGCCGAACGGCAGAGCGCGGACGCGCGGCGACGCCTCACGGCGCTCGATGTGGATCAGGCCATTGC
ACGCGCGCAAGCCGATGCCGCCAACGCCGCCACAAATGCGGCGGCGGCCAGTGGACCCGCGCTCGCGGCGGCCGAAGAAG
CCGCCCGCATCGCCCGCATCGGCTATCGGGAGGGCAAGTTCAGCCAGCTCGATCTACTCGATGCCGAACGCACGCTAGCC
GGAACGCGAGCGGCGGCGATCGACGCTCTGCTCTCCTACCACATCGCCCAGGCGCAGCTTGAGCGGCTTACCGCCCGCGC
GCCGGTCACACAGGGGGAATGA

Upstream 100 bases:

>100_bases
CGAGCGCGCCCGATCCAACTCACCGACCTCCAAAGGCATGACGATTCCAGCCTAGTCCCATCCGTGGGACTCCCCCGGAA
TTATCAGGAGTCTTTCGATC

Downstream 100 bases:

>100_bases
CAATGAAGACCCGTTACATAGCGGCCTTGCCGCTGACATTCGCCGCACTCCTTATGGTTGGATGTTCCGGCGGCGATCAA
CCCGCCGACAATGCGCAGAA

Product: outer membrane efflux protein

Products: NA

Alternate protein names: Cation efflux system protein CzcC [H]

Number of amino acids: Translated: 433; Mature: 433

Protein sequence:

>433_residues
MHRLLAALLAATACATIAQAQTSSPVDTGAAQPQSTSPALMGPAFTVDRALELAGVVSPALEAASADIRAAEAGRRVAGL
RPNPSVTVEAENVAGSGPYRGTQSLEATTSLTLPIELGGKRSARIAVADARTDRATIQATIAQADLRLNVIRAYAEAASA
ERRLITAHDQARIANETLRAAQVRVQAGRASPIEAERANVARVNADAALTREERAVEVARFTLSRIIGQPIAGPLDTDWF
SRVPATYGPLRPIDSTGTLMMAAANADFAIADAGVRLARSQRVPDLTLGAGARRLEQTNDTAAIFSLSIPIPMFNNGRAA
LSQATAERQSADARRRLTALDVDQAIARAQADAANAATNAAAASGPALAAAEEAARIARIGYREGKFSQLDLLDAERTLA
GTRAAAIDALLSYHIAQAQLERLTARAPVTQGE

Sequences:

>Translated_433_residues
MHRLLAALLAATACATIAQAQTSSPVDTGAAQPQSTSPALMGPAFTVDRALELAGVVSPALEAASADIRAAEAGRRVAGL
RPNPSVTVEAENVAGSGPYRGTQSLEATTSLTLPIELGGKRSARIAVADARTDRATIQATIAQADLRLNVIRAYAEAASA
ERRLITAHDQARIANETLRAAQVRVQAGRASPIEAERANVARVNADAALTREERAVEVARFTLSRIIGQPIAGPLDTDWF
SRVPATYGPLRPIDSTGTLMMAAANADFAIADAGVRLARSQRVPDLTLGAGARRLEQTNDTAAIFSLSIPIPMFNNGRAA
LSQATAERQSADARRRLTALDVDQAIARAQADAANAATNAAAASGPALAAAEEAARIARIGYREGKFSQLDLLDAERTLA
GTRAAAIDALLSYHIAQAQLERLTARAPVTQGE
>Mature_433_residues
MHRLLAALLAATACATIAQAQTSSPVDTGAAQPQSTSPALMGPAFTVDRALELAGVVSPALEAASADIRAAEAGRRVAGL
RPNPSVTVEAENVAGSGPYRGTQSLEATTSLTLPIELGGKRSARIAVADARTDRATIQATIAQADLRLNVIRAYAEAASA
ERRLITAHDQARIANETLRAAQVRVQAGRASPIEAERANVARVNADAALTREERAVEVARFTLSRIIGQPIAGPLDTDWF
SRVPATYGPLRPIDSTGTLMMAAANADFAIADAGVRLARSQRVPDLTLGAGARRLEQTNDTAAIFSLSIPIPMFNNGRAA
LSQATAERQSADARRRLTALDVDQAIARAQADAANAATNAAAASGPALAAAEEAARIARIGYREGKFSQLDLLDAERTLA
GTRAAAIDALLSYHIAQAQLERLTARAPVTQGE

Specific function: CzcC protein appears to modify the specificity of the system, perhaps by acting on the CzcB protein. When the CzcC protein is added to CzcA and CzcB, the efflux system gains specificity for cadmium and cobalt [H]

COG id: COG1538

COG function: function code MU; Outer membrane protein

Gene ontology:

Cell location: Cell outer membrane (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003423 [H]

Pfam domain/function: PF02321 OEP [H]

EC number: NA

Molecular weight: Translated: 45123; Mature: 45123

Theoretical pI: Translated: 9.07; Mature: 9.07

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHRLLAALLAATACATIAQAQTSSPVDTGAAQPQSTSPALMGPAFTVDRALELAGVVSPA
CHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHH
LEAASADIRAAEAGRRVAGLRPNPSVTVEAENVAGSGPYRGTQSLEATTSLTLPIELGGK
HHHHHCHHHHHHCCCCEECCCCCCCEEEEECCCCCCCCCCCCCCCCCEEEEEEEEEECCC
RSARIAVADARTDRATIQATIAQADLRLNVIRAYAEAASAERRLITAHDQARIANETLRA
CCCEEEEEECCCCCHHEEEEHHHHHHHHHHHHHHHHHHHHCCEEEECCHHHHHHHHHHHH
AQVRVQAGRASPIEAERANVARVNADAALTREERAVEVARFTLSRIIGQPIAGPLDTDWF
HHHEEECCCCCCCCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHH
SRVPATYGPLRPIDSTGTLMMAAANADFAIADAGVRLARSQRVPDLTLGAGARRLEQTND
HHCCCCCCCCCCCCCCCCEEEEECCCCEEEEHHHHHHHHHCCCCCEEECCCHHHHHCCCC
TAAIFSLSIPIPMFNNGRAALSQATAERQSADARRRLTALDVDQAIARAQADAANAATNA
CEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
AAASGPALAAAEEAARIARIGYREGKFSQLDLLDAERTLAGTRAAAIDALLSYHIAQAQL
CCCCCCHHHHHHHHHHHHHHCCCCCCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHH
ERLTARAPVTQGE
HHHHHHCCCCCCC
>Mature Secondary Structure
MHRLLAALLAATACATIAQAQTSSPVDTGAAQPQSTSPALMGPAFTVDRALELAGVVSPA
CHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHH
LEAASADIRAAEAGRRVAGLRPNPSVTVEAENVAGSGPYRGTQSLEATTSLTLPIELGGK
HHHHHCHHHHHHCCCCEECCCCCCCEEEEECCCCCCCCCCCCCCCCCEEEEEEEEEECCC
RSARIAVADARTDRATIQATIAQADLRLNVIRAYAEAASAERRLITAHDQARIANETLRA
CCCEEEEEECCCCCHHEEEEHHHHHHHHHHHHHHHHHHHHCCEEEECCHHHHHHHHHHHH
AQVRVQAGRASPIEAERANVARVNADAALTREERAVEVARFTLSRIIGQPIAGPLDTDWF
HHHEEECCCCCCCCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHH
SRVPATYGPLRPIDSTGTLMMAAANADFAIADAGVRLARSQRVPDLTLGAGARRLEQTND
HHCCCCCCCCCCCCCCCCEEEEECCCCEEEEHHHHHHHHHCCCCCEEECCCHHHHHCCCC
TAAIFSLSIPIPMFNNGRAALSQATAERQSADARRRLTALDVDQAIARAQADAANAATNA
CEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
AAASGPALAAAEEAARIARIGYREGKFSQLDLLDAERTLAGTRAAAIDALLSYHIAQAQL
CCCCCCHHHHHHHHHHHHHHCCCCCCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHH
ERLTARAPVTQGE
HHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2678100; 7766206 [H]