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The map label for this gene is cusB [H]

Identifier: 103488027

GI number: 103488027

Start: 2687221

End: 2688693

Strand: Direct

Name: cusB [H]

Synonym: Sala_2549

Alternate gene names: 103488027

Gene position: 2687221-2688693 (Clockwise)

Preceding gene: 103488026

Following gene: 103488028

Centisome position: 80.33

GC content: 67.41

Gene sequence:

>1473_bases
ATGAAGCACGCACTTTCCGCGCGGGCGCGGCTCCTTCTGGCCGCAGCGGCGATTGCCCTGGTCGGGGGTGCCGTTGGCTA
TGGCGTGGCCAGCTTGAGCGGCACCGGGCCGGCAGCCGAGAGGACCGAAGGGGACCGCAAGGTGCTCTACTGGTATGACC
CCATGTATCCCAACCAGCATTTCGACAAGCCCGGCAAGTCGCCGTTCATGGATATGGAGCTCGTCCCCAAATATGCCGAT
GAGGCAACAAGCGAGGCAGGGGTGCGCATCGATCCGGCGCTCGTCCAGAATCTGGGCGTGCGCACGGCCGAGGTCCGCCG
CGGCACGCTGGGCGGCGGCCTCTCGGCCACAGGCGTCATCGGCTATAACGAGCGCGAGATAGCGATTGTCCAGCCGCGCG
CCGGCGGCTTTGTCCAGCGGACCTATGGGCGGGCGCCCGATGACGTGATCGAAGCAGGCGCGCCGCTGGTCGATCTGCTT
GTGCCGGACTGGGGCGGCGCACAGGCCGAGTTCCTGGCGGTGCTGCGCACGGGCGACAGGGCCCTGGCAAGCGCCGCGCG
CCAAAGGCTGGTGCTGCTCGGCATGCCGCAATCCACCATTGCCGCCGTCGAACGCAGTGGCAGGCAGCGCAATGTCATTA
CCATCAACTCGCCGATTGGCGGGACGATCAAGTCGCTCGGCGTGCGGCAGGGTATGAGCGTGATGGCGGGGCAAACGCTC
GCCGAAGTAAACGGGCTCGGCACGGTGTGGCTCGATGCCGCGGTCCCCGAAGCCATGGCGGGACGATTGCGGCCGGACAT
GCCGGTGACGGCGACGCTGGCAGCCTATCCGGGCGAGAGTTTTGCGGGCCGGATTCGGGCGATCCTGCCGCAGGCTGAAA
CCGAAAGCCGGACCATCACCGCGCGCGTCGAGATCCCCAATCGCGGCGGGCGGCTGCGGCCAGGCATGTTCGCCACCGTC
AGCTTCGCTGGCGAGCAGCGCCCCGCGCTGCTCGTACCCTCCGAGGCGCTGATCCGCACGGGCAAGCGCACGCTCGTCAT
GCTGGCGTTGGATAAGGGACGCTATCAGCCGGCCGAAGTCAGAACGGGAATGGAAGCGGACGGCCAAACCGAAGTGCTCG
CCGGACTTGCCGAGGGTGAGAAGGTCGTCACCTCGGGCCAGTTCCTGATCGATTCCGAAGCCAGTCTTTCGGCAATGCAG
GCGCGGCCGATCGCGGGTGGTTCGCCGCAGGCGCCGTCCAAGGCTCAGGGCCACAGGGCTATCGGCACAATCGAAAAGAT
CGAGCCCGGCAGCGTGACGCTGAGGCATGGGCCGGTCCCGTCGGCGAGTTGGCCCGCAATGACGATGCGCTTCCGGCTTG
CCGATCCTGCAACGGTGCGCGGGTTCAAACCCGGCGACAAGGTGAACTTCACCTTCGACCAGCCTGCGCAAGGCCCGACC
GTCCGCTCGATCACGCGCGAGAACGGCCGATGA

Upstream 100 bases:

>100_bases
CCGAGGCGAGCCTCGCCCGGACAGAACTCGACGCACTCGACCGCGAGGCTGCTGTAGCCCGGCACGAAGCGCGCCTGACG
TTGACCTACGGAGACGATCG

Downstream 100 bases:

>100_bases
TCGCGCGGCTCATCCATTGGTCGGTCCAGAACCGCTTCTTCATATTGCTGGGCGCGCTGGCCTTGGTGTTCGCGGGGCTC
TGGGCGGTGCGAACGACACC

Product: secretion protein HlyD

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 490; Mature: 490

Protein sequence:

>490_residues
MKHALSARARLLLAAAAIALVGGAVGYGVASLSGTGPAAERTEGDRKVLYWYDPMYPNQHFDKPGKSPFMDMELVPKYAD
EATSEAGVRIDPALVQNLGVRTAEVRRGTLGGGLSATGVIGYNEREIAIVQPRAGGFVQRTYGRAPDDVIEAGAPLVDLL
VPDWGGAQAEFLAVLRTGDRALASAARQRLVLLGMPQSTIAAVERSGRQRNVITINSPIGGTIKSLGVRQGMSVMAGQTL
AEVNGLGTVWLDAAVPEAMAGRLRPDMPVTATLAAYPGESFAGRIRAILPQAETESRTITARVEIPNRGGRLRPGMFATV
SFAGEQRPALLVPSEALIRTGKRTLVMLALDKGRYQPAEVRTGMEADGQTEVLAGLAEGEKVVTSGQFLIDSEASLSAMQ
ARPIAGGSPQAPSKAQGHRAIGTIEKIEPGSVTLRHGPVPSASWPAMTMRFRLADPATVRGFKPGDKVNFTFDQPAQGPT
VRSITRENGR

Sequences:

>Translated_490_residues
MKHALSARARLLLAAAAIALVGGAVGYGVASLSGTGPAAERTEGDRKVLYWYDPMYPNQHFDKPGKSPFMDMELVPKYAD
EATSEAGVRIDPALVQNLGVRTAEVRRGTLGGGLSATGVIGYNEREIAIVQPRAGGFVQRTYGRAPDDVIEAGAPLVDLL
VPDWGGAQAEFLAVLRTGDRALASAARQRLVLLGMPQSTIAAVERSGRQRNVITINSPIGGTIKSLGVRQGMSVMAGQTL
AEVNGLGTVWLDAAVPEAMAGRLRPDMPVTATLAAYPGESFAGRIRAILPQAETESRTITARVEIPNRGGRLRPGMFATV
SFAGEQRPALLVPSEALIRTGKRTLVMLALDKGRYQPAEVRTGMEADGQTEVLAGLAEGEKVVTSGQFLIDSEASLSAMQ
ARPIAGGSPQAPSKAQGHRAIGTIEKIEPGSVTLRHGPVPSASWPAMTMRFRLADPATVRGFKPGDKVNFTFDQPAQGPT
VRSITRENGR
>Mature_490_residues
MKHALSARARLLLAAAAIALVGGAVGYGVASLSGTGPAAERTEGDRKVLYWYDPMYPNQHFDKPGKSPFMDMELVPKYAD
EATSEAGVRIDPALVQNLGVRTAEVRRGTLGGGLSATGVIGYNEREIAIVQPRAGGFVQRTYGRAPDDVIEAGAPLVDLL
VPDWGGAQAEFLAVLRTGDRALASAARQRLVLLGMPQSTIAAVERSGRQRNVITINSPIGGTIKSLGVRQGMSVMAGQTL
AEVNGLGTVWLDAAVPEAMAGRLRPDMPVTATLAAYPGESFAGRIRAILPQAETESRTITARVEIPNRGGRLRPGMFATV
SFAGEQRPALLVPSEALIRTGKRTLVMLALDKGRYQPAEVRTGMEADGQTEVLAGLAEGEKVVTSGQFLIDSEASLSAMQ
ARPIAGGSPQAPSKAQGHRAIGTIEKIEPGSVTLRHGPVPSASWPAMTMRFRLADPATVRGFKPGDKVNFTFDQPAQGPT
VRSITRENGR

Specific function: Part of a cation efflux system that mediates resistance to copper and silver [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family [H]

Homologues:

Organism=Escherichia coli, GI1786787, Length=386, Percent_Identity=42.2279792746114, Blast_Score=305, Evalue=3e-84,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006143 [H]

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 51771; Mature: 51771

Theoretical pI: Translated: 10.22; Mature: 10.22

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKHALSARARLLLAAAAIALVGGAVGYGVASLSGTGPAAERTEGDRKVLYWYDPMYPNQH
CCCHHHHHHHHHHHHHHHHHHHHHHHHCCEECCCCCCCCCCCCCCCEEEEEECCCCCCCC
FDKPGKSPFMDMELVPKYADEATSEAGVRIDPALVQNLGVRTAEVRRGTLGGGLSATGVI
CCCCCCCCCCCHHHCCHHHHHHHCCCCCEECHHHHHHCCCCCHHHHCCCCCCCCCEEEEE
GYNEREIAIVQPRAGGFVQRTYGRAPDDVIEAGAPLVDLLVPDWGGAQAEFLAVLRTGDR
ECCCCEEEEECCCCCCCHHHHCCCCCHHHHHCCCCEEEEECCCCCCCHHHEEEEHHCCCH
ALASAARQRLVLLGMPQSTIAAVERSGRQRNVITINSPIGGTIKSLGVRQGMSVMAGQTL
HHHHHHHCEEEEEECCHHHHHHHHHCCCCCCEEEECCCCCCHHHHHHHHCCHHHHHCCHH
AEVNGLGTVWLDAAVPEAMAGRLRPDMPVTATLAAYPGESFAGRIRAILPQAETESRTIT
HHHCCCCEEEEHHHCCHHHHHCCCCCCCEEEEEEECCCCHHHHHHHEECCCCCCCCEEEE
ARVEIPNRGGRLRPGMFATVSFAGEQRPALLVPSEALIRTGKRTLVMLALDKGRYQPAEV
EEEEECCCCCCCCCCEEEEEEECCCCCCEEECCCHHHHHCCCEEEEEEEECCCCCCHHHH
RTGMEADGQTEVLAGLAEGEKVVTSGQFLIDSEASLSAMQARPIAGGSPQAPSKAQGHRA
HCCCCCCCCHHHHHHHHCCCEEEECCCEEEECCCCHHHHHCCCCCCCCCCCCCCCCCCCH
IGTIEKIEPGSVTLRHGPVPSASWPAMTMRFRLADPATVRGFKPGDKVNFTFDQPAQGPT
HCCCEECCCCCEEEECCCCCCCCCCEEEEEEEECCCCEECCCCCCCEEEEEECCCCCCCC
VRSITRENGR
CHHHHCCCCC
>Mature Secondary Structure
MKHALSARARLLLAAAAIALVGGAVGYGVASLSGTGPAAERTEGDRKVLYWYDPMYPNQH
CCCHHHHHHHHHHHHHHHHHHHHHHHHCCEECCCCCCCCCCCCCCCEEEEEECCCCCCCC
FDKPGKSPFMDMELVPKYADEATSEAGVRIDPALVQNLGVRTAEVRRGTLGGGLSATGVI
CCCCCCCCCCCHHHCCHHHHHHHCCCCCEECHHHHHHCCCCCHHHHCCCCCCCCCEEEEE
GYNEREIAIVQPRAGGFVQRTYGRAPDDVIEAGAPLVDLLVPDWGGAQAEFLAVLRTGDR
ECCCCEEEEECCCCCCCHHHHCCCCCHHHHHCCCCEEEEECCCCCCCHHHEEEEHHCCCH
ALASAARQRLVLLGMPQSTIAAVERSGRQRNVITINSPIGGTIKSLGVRQGMSVMAGQTL
HHHHHHHCEEEEEECCHHHHHHHHHCCCCCCEEEECCCCCCHHHHHHHHCCHHHHHCCHH
AEVNGLGTVWLDAAVPEAMAGRLRPDMPVTATLAAYPGESFAGRIRAILPQAETESRTIT
HHHCCCCEEEEHHHCCHHHHHCCCCCCCEEEEEEECCCCHHHHHHHEECCCCCCCCEEEE
ARVEIPNRGGRLRPGMFATVSFAGEQRPALLVPSEALIRTGKRTLVMLALDKGRYQPAEV
EEEEECCCCCCCCCCEEEEEEECCCCCCEEECCCHHHHHCCCEEEEEEEECCCCCCHHHH
RTGMEADGQTEVLAGLAEGEKVVTSGQFLIDSEASLSAMQARPIAGGSPQAPSKAQGHRA
HCCCCCCCCHHHHHHHHCCCEEEECCCEEEECCCCHHHHHCCCCCCCCCCCCCCCCCCCH
IGTIEKIEPGSVTLRHGPVPSASWPAMTMRFRLADPATVRGFKPGDKVNFTFDQPAQGPT
HCCCEECCCCCEEEECCCCCCCCCCEEEEEEEECCCCEECCCCCCCEEEEEECCCCCCCC
VRSITRENGR
CHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]