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The map label for this gene is adhA [H]

Identifier: 103487934

GI number: 103487934

Start: 2596523

End: 2597548

Strand: Direct

Name: adhA [H]

Synonym: Sala_2455

Alternate gene names: 103487934

Gene position: 2596523-2597548 (Clockwise)

Preceding gene: 103487933

Following gene: 103487935

Centisome position: 77.62

GC content: 65.59

Gene sequence:

>1026_bases
ATGGCGAAAACCATGAAGGCGGCGGTCGTCCGCGAATTCGGTAAGCCGCTGGTCATCGAAGAAGCGCCGATCCCGACGGT
CGGACCCGGCCAGATCCTGGTAAAGGTCGCGGCGGCCGGCGTATGCCACACCGACCTGCATGCGGCCGAGGGCGACTGGC
CGGTCAAGCCCAACCCGCCCTTCATTCCCGGGCATGAAGGCGTCGGACATGTCGCCGCCGTCGGATCGGGCGTCACTCTC
ATAAAAGAGGGCGACCGGGTCGGCGTCCCCTGGCTCTACTCCGCCTGCGGGCATTGCGTGCATTGCCTGGGCGGCTGGGA
GACGTTGTGCGAGAGCCAGCAGAATACCGGCTATTCGGTGAATGGCAGCTTCGCGGAATATGTCCTCGCCGATCCAAATT
ATGTCGGGCATCTTCCCGACAATGTCGACTTCCTCGACATCGCGCCGATCCTCTGCGCCGGCGTCACCGTCTATAAAGGG
CTGAAGGCCACCGAGGCGAAGCCCGGAGAGTGGGTGGTCGTCTCCGGGATCGGCGGGCTCGGCCACATGGCGGTGCAATA
TGCCCGCGCGATGGGTCTCAATGTGGCGGCGGTCGACGTCGACGACCGCAAGCTCGATCTCGCGACCCGTCTCGGCGCGG
CGCTCACGGTCAACGCGCGCGAGGAGGATCCGTCAGCCGCCATCAAGCAGGCGATCGACGGTGCGCAGGGCGTCCTCGTC
ACCGCGGTCTCGCCCAAGGCCTTCCAGCAGGCGCTCGGCATGGTCCGGCGCGGTGGTACGGTCGCGCTCAACGGCCTTCC
ACCGGGCGATTTTCCGCTGTCGATCTTCGACACCGTACTCAACGGCATCACCGTTCGCGGTTCGATCGTCGGCACCCGGC
TCGACCTTCTCGAAGCACTGGCCTTCGCCGGCGAAGGCAAGGTGCATGCGACGGTGCACGCCGAAAAGCTGGAGAACATC
AACGACGTCTTTGCGCGCATGCGCCGCGGCGACATTGACGGGCGGATCGTTCTCGATCTGGCCTGA

Upstream 100 bases:

>100_bases
GATGATGCTCGACCATTATCAGCAGACCAAGAACCTGCTCGTCTCCTATGACGAGCATGCGCTCGGCCTGTTCTGATCCC
TCCCGGAAGGAGAAGCAGAC

Downstream 100 bases:

>100_bases
CCATCTTCTGGCGAAAGAAACATTCAATGCCCCTCCTTCATAGCTTGCCGATCGCACGGCGCCACTTCGTTCAGGGGCTG
GCGATTGGCGGAGCCGTCGC

Product: alcohol dehydrogenase GroES-like protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 341; Mature: 340

Protein sequence:

>341_residues
MAKTMKAAVVREFGKPLVIEEAPIPTVGPGQILVKVAAAGVCHTDLHAAEGDWPVKPNPPFIPGHEGVGHVAAVGSGVTL
IKEGDRVGVPWLYSACGHCVHCLGGWETLCESQQNTGYSVNGSFAEYVLADPNYVGHLPDNVDFLDIAPILCAGVTVYKG
LKATEAKPGEWVVVSGIGGLGHMAVQYARAMGLNVAAVDVDDRKLDLATRLGAALTVNAREEDPSAAIKQAIDGAQGVLV
TAVSPKAFQQALGMVRRGGTVALNGLPPGDFPLSIFDTVLNGITVRGSIVGTRLDLLEALAFAGEGKVHATVHAEKLENI
NDVFARMRRGDIDGRIVLDLA

Sequences:

>Translated_341_residues
MAKTMKAAVVREFGKPLVIEEAPIPTVGPGQILVKVAAAGVCHTDLHAAEGDWPVKPNPPFIPGHEGVGHVAAVGSGVTL
IKEGDRVGVPWLYSACGHCVHCLGGWETLCESQQNTGYSVNGSFAEYVLADPNYVGHLPDNVDFLDIAPILCAGVTVYKG
LKATEAKPGEWVVVSGIGGLGHMAVQYARAMGLNVAAVDVDDRKLDLATRLGAALTVNAREEDPSAAIKQAIDGAQGVLV
TAVSPKAFQQALGMVRRGGTVALNGLPPGDFPLSIFDTVLNGITVRGSIVGTRLDLLEALAFAGEGKVHATVHAEKLENI
NDVFARMRRGDIDGRIVLDLA
>Mature_340_residues
AKTMKAAVVREFGKPLVIEEAPIPTVGPGQILVKVAAAGVCHTDLHAAEGDWPVKPNPPFIPGHEGVGHVAAVGSGVTLI
KEGDRVGVPWLYSACGHCVHCLGGWETLCESQQNTGYSVNGSFAEYVLADPNYVGHLPDNVDFLDIAPILCAGVTVYKGL
KATEAKPGEWVVVSGIGGLGHMAVQYARAMGLNVAAVDVDDRKLDLATRLGAALTVNAREEDPSAAIKQAIDGAQGVLVT
AVSPKAFQQALGMVRRGGTVALNGLPPGDFPLSIFDTVLNGITVRGSIVGTRLDLLEALAFAGEGKVHATVHAEKLENIN
DVFARMRRGDIDGRIVLDLA

Specific function: Preferred Specificity Is Towards 1-Propanol. [C]

COG id: COG1064

COG function: function code R; Zn-dependent alcohol dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the zinc-containing alcohol dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4501933, Length=359, Percent_Identity=28.4122562674095, Blast_Score=100, Evalue=2e-21,
Organism=Homo sapiens, GI34577061, Length=359, Percent_Identity=28.133704735376, Blast_Score=99, Evalue=4e-21,
Organism=Homo sapiens, GI4501929, Length=359, Percent_Identity=28.133704735376, Blast_Score=94, Evalue=2e-19,
Organism=Homo sapiens, GI71565154, Length=251, Percent_Identity=31.0756972111554, Blast_Score=93, Evalue=5e-19,
Organism=Homo sapiens, GI262073058, Length=254, Percent_Identity=27.9527559055118, Blast_Score=92, Evalue=7e-19,
Organism=Homo sapiens, GI71743840, Length=254, Percent_Identity=27.9527559055118, Blast_Score=92, Evalue=8e-19,
Organism=Homo sapiens, GI71565152, Length=365, Percent_Identity=25.2054794520548, Blast_Score=91, Evalue=2e-18,
Organism=Homo sapiens, GI194239674, Length=299, Percent_Identity=28.7625418060201, Blast_Score=90, Evalue=3e-18,
Organism=Homo sapiens, GI13236495, Length=299, Percent_Identity=28.7625418060201, Blast_Score=90, Evalue=3e-18,
Organism=Homo sapiens, GI194239676, Length=242, Percent_Identity=30.5785123966942, Blast_Score=86, Evalue=6e-17,
Organism=Homo sapiens, GI156523966, Length=239, Percent_Identity=28.4518828451883, Blast_Score=80, Evalue=3e-15,
Organism=Homo sapiens, GI4501939, Length=239, Percent_Identity=28.4518828451883, Blast_Score=80, Evalue=3e-15,
Organism=Escherichia coli, GI87081918, Length=337, Percent_Identity=45.1038575667656, Blast_Score=250, Evalue=7e-68,
Organism=Escherichia coli, GI1786518, Length=323, Percent_Identity=34.3653250773994, Blast_Score=159, Evalue=4e-40,
Organism=Escherichia coli, GI87082401, Length=337, Percent_Identity=31.4540059347181, Blast_Score=130, Evalue=9e-32,
Organism=Escherichia coli, GI1790045, Length=344, Percent_Identity=30.2325581395349, Blast_Score=130, Evalue=9e-32,
Organism=Escherichia coli, GI1788073, Length=272, Percent_Identity=34.1911764705882, Blast_Score=130, Evalue=1e-31,
Organism=Escherichia coli, GI87082125, Length=221, Percent_Identity=35.7466063348416, Blast_Score=105, Evalue=5e-24,
Organism=Escherichia coli, GI226510992, Length=330, Percent_Identity=30, Blast_Score=98, Evalue=8e-22,
Organism=Escherichia coli, GI1786552, Length=242, Percent_Identity=35.1239669421488, Blast_Score=89, Evalue=4e-19,
Organism=Escherichia coli, GI1788407, Length=284, Percent_Identity=30.9859154929577, Blast_Score=89, Evalue=5e-19,
Organism=Escherichia coli, GI1788075, Length=285, Percent_Identity=30.8771929824561, Blast_Score=89, Evalue=6e-19,
Organism=Escherichia coli, GI1787863, Length=296, Percent_Identity=27.7027027027027, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI1786825, Length=308, Percent_Identity=28.8961038961039, Blast_Score=78, Evalue=1e-15,
Organism=Escherichia coli, GI1790485, Length=327, Percent_Identity=26.605504587156, Blast_Score=72, Evalue=5e-14,
Organism=Escherichia coli, GI1790718, Length=201, Percent_Identity=27.363184079602, Blast_Score=70, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17562584, Length=342, Percent_Identity=39.4736842105263, Blast_Score=225, Evalue=3e-59,
Organism=Caenorhabditis elegans, GI71988145, Length=342, Percent_Identity=36.2573099415205, Blast_Score=210, Evalue=7e-55,
Organism=Caenorhabditis elegans, GI17562582, Length=347, Percent_Identity=38.328530259366, Blast_Score=202, Evalue=2e-52,
Organism=Caenorhabditis elegans, GI17562876, Length=337, Percent_Identity=31.1572700296736, Blast_Score=123, Evalue=1e-28,
Organism=Caenorhabditis elegans, GI17562878, Length=336, Percent_Identity=30.6547619047619, Blast_Score=109, Evalue=2e-24,
Organism=Caenorhabditis elegans, GI17507255, Length=266, Percent_Identity=28.5714285714286, Blast_Score=79, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI25146526, Length=252, Percent_Identity=29.7619047619048, Blast_Score=73, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI71997431, Length=254, Percent_Identity=29.1338582677165, Blast_Score=69, Evalue=4e-12,
Organism=Saccharomyces cerevisiae, GI6319621, Length=345, Percent_Identity=39.7101449275362, Blast_Score=248, Evalue=1e-66,
Organism=Saccharomyces cerevisiae, GI6323961, Length=343, Percent_Identity=39.3586005830904, Blast_Score=244, Evalue=2e-65,
Organism=Saccharomyces cerevisiae, GI6324486, Length=343, Percent_Identity=38.4839650145773, Blast_Score=237, Evalue=3e-63,
Organism=Saccharomyces cerevisiae, GI6323729, Length=343, Percent_Identity=38.7755102040816, Blast_Score=232, Evalue=6e-62,
Organism=Saccharomyces cerevisiae, GI6319949, Length=343, Percent_Identity=30.3206997084548, Blast_Score=115, Evalue=7e-27,
Organism=Saccharomyces cerevisiae, GI6323980, Length=319, Percent_Identity=28.5266457680251, Blast_Score=100, Evalue=3e-22,
Organism=Saccharomyces cerevisiae, GI6320033, Length=243, Percent_Identity=32.0987654320988, Blast_Score=89, Evalue=7e-19,
Organism=Saccharomyces cerevisiae, GI6322619, Length=250, Percent_Identity=32.4, Blast_Score=87, Evalue=3e-18,
Organism=Saccharomyces cerevisiae, GI6319955, Length=250, Percent_Identity=32.4, Blast_Score=87, Evalue=3e-18,
Organism=Saccharomyces cerevisiae, GI6323099, Length=331, Percent_Identity=25.3776435045317, Blast_Score=76, Evalue=1e-14,
Organism=Drosophila melanogaster, GI17137530, Length=348, Percent_Identity=27.0114942528736, Blast_Score=86, Evalue=3e-17,
Organism=Drosophila melanogaster, GI17737897, Length=332, Percent_Identity=26.8072289156627, Blast_Score=83, Evalue=3e-16,
Organism=Drosophila melanogaster, GI17737895, Length=252, Percent_Identity=26.984126984127, Blast_Score=82, Evalue=5e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013149
- InterPro:   IPR013154
- InterPro:   IPR002085
- InterPro:   IPR002328
- InterPro:   IPR011032
- InterPro:   IPR016040 [H]

Pfam domain/function: PF08240 ADH_N; PF00107 ADH_zinc_N [H]

EC number: =1.1.1.1 [H]

Molecular weight: Translated: 35643; Mature: 35512

Theoretical pI: Translated: 5.78; Mature: 5.78

Prosite motif: PS00059 ADH_ZINC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKTMKAAVVREFGKPLVIEEAPIPTVGPGQILVKVAAAGVCHTDLHAAEGDWPVKPNPP
CCCHHHHHHHHHCCCCEEEECCCCCCCCCHHHHHHHHHCCCEECCCCCCCCCCCCCCCCC
FIPGHEGVGHVAAVGSGVTLIKEGDRVGVPWLYSACGHCVHCLGGWETLCESQQNTGYSV
CCCCCCCCCHHEECCCCEEEEECCCCCCCCHHHHHHHHHHHHHCCHHHHHCCCCCCCEEE
NGSFAEYVLADPNYVGHLPDNVDFLDIAPILCAGVTVYKGLKATEAKPGEWVVVSGIGGL
CCCEEEEEEECCCEECCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEECCCCH
GHMAVQYARAMGLNVAAVDVDDRKLDLATRLGAALTVNAREEDPSAAIKQAIDGAQGVLV
HHHHHHHHHHHCCEEEEEECCCCHHHHHHHCCCEEEEECCCCCHHHHHHHHHCCCCCEEE
TAVSPKAFQQALGMVRRGGTVALNGLPPGDFPLSIFDTVLNGITVRGSIVGTRLDLLEAL
EEECHHHHHHHHHHHHCCCEEEECCCCCCCCCHHHHHHHHCCEEEECEEHHHHHHHHHHH
AFAGEGKVHATVHAEKLENINDVFARMRRGDIDGRIVLDLA
HHCCCCCEEEEEEHHHHCCHHHHHHHHHCCCCCCEEEEEEC
>Mature Secondary Structure 
AKTMKAAVVREFGKPLVIEEAPIPTVGPGQILVKVAAAGVCHTDLHAAEGDWPVKPNPP
CCHHHHHHHHHCCCCEEEECCCCCCCCCHHHHHHHHHCCCEECCCCCCCCCCCCCCCCC
FIPGHEGVGHVAAVGSGVTLIKEGDRVGVPWLYSACGHCVHCLGGWETLCESQQNTGYSV
CCCCCCCCCHHEECCCCEEEEECCCCCCCCHHHHHHHHHHHHHCCHHHHHCCCCCCCEEE
NGSFAEYVLADPNYVGHLPDNVDFLDIAPILCAGVTVYKGLKATEAKPGEWVVVSGIGGL
CCCEEEEEEECCCEECCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEECCCCH
GHMAVQYARAMGLNVAAVDVDDRKLDLATRLGAALTVNAREEDPSAAIKQAIDGAQGVLV
HHHHHHHHHHHCCEEEEEECCCCHHHHHHHCCCEEEEECCCCCHHHHHHHHHCCCCCEEE
TAVSPKAFQQALGMVRRGGTVALNGLPPGDFPLSIFDTVLNGITVRGSIVGTRLDLLEAL
EEECHHHHHHHHHHHHCCCEEEECCCCCCCCCHHHHHHHHCCEEEECEEHHHHHHHHHHH
AFAGEGKVHATVHAEKLENINDVFARMRRGDIDGRIVLDLA
HHCCCCCEEEEEEHHHHCCHHHHHHHHHCCCCCCEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9659380; 11481432 [H]