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The map label for this gene is clpB [H]

Identifier: 103487872

GI number: 103487872

Start: 2523934

End: 2526513

Strand: Direct

Name: clpB [H]

Synonym: Sala_2391

Alternate gene names: 103487872

Gene position: 2523934-2526513 (Clockwise)

Preceding gene: 103487870

Following gene: 103487879

Centisome position: 75.45

GC content: 66.55

Gene sequence:

>2580_bases
ATGAACCTCGAAAAATTCACCGACCGCGCCAAGGGCTTTTTGCAGGCGGCGCAGACGATCGCGATCCGCATGAATCATCA
GCGGATCAGCCCCGAACATATCGCCAAGGCGCTGCTCGAAGACAGTCAGGGCATGGCCGCCGGGCTGATCGCCAACAGCG
GCGGCGACACCGCACGTGCGGTGGCGGGTATCGACGCGCTGCTCGCCAAGCTGCCCGCGGTGTCGGGATCGGGCGCGCAG
GCGACGCCGGGGCTCGACAACGACGCGGTGCGCCTGCTCGACCAGGCCGAACAGGTCGCCGCAAAGGCCGGCAGCGAATA
TGTCGCGGTCCAGAATATCCTCCTCGCCATGGTGCTGGCGCCCAGCACCCCGGTCGGCAAGGCCTTCGCCGACGCGGGCG
TATCCGCAGACGCCTTGAACGCGGCGATCGCCAAGCTCACCGGCGGTCGCACCGCCGATACCGCATCGGCCGAAGATCGC
TATGACGCGCTCAGGAAATTCGCCCGCGACCTCACCGAGGTAGCGCGCGAGGGCAAGCTGGATCCCGTGATCGGCCGCGA
CGAGGAAATCCGCCGCACGGTGCAGATCCTTGCGCGCCGCACCAAGAACAATCCCGTGTTGATCGGCGAGCCGGGCGTCG
GCAAGACCGCGATCGCCGAGGGCCTTGCGCTGCGCATCGTCAACGGCGACGTGCCCGACAGCCTGAAGGACCGCCGTCTG
CTCGCGCTCGACATGGGCGCGCTGATCGCCGGCGCCAAATATCGCGGCGAGTTCGAGGAGCGGCTCAAGGGCGTGCTCGA
CGATGTGAAGGCCGCCGAGGGCGAGATCATCCTCTTCATCGACGAAATGCACACGCTCGTCGGCGCGGGAAAATCCGAAG
GCGCGATGGACGCCTCGAACCTGCTCAAGCCCGCGCTCGCGCGCGGCGAGCTCCACTGCATCGGCGCGACGACGCTCGAC
GAATATCGCAAGCATGTCGAAAAGGATCCCGCGCTCCAGCGGCGCTTTCAGCCGGTGTTCGTCGGCGAACCAACGGTCGA
GGATTCGATCTCGATCCTGCGTGGGATCAAGGAGAAATACGAGCTGCACCACGGCGTGCGCATCACCGACGGCGCGATCG
TCGCCGCGGCGACGCTGTCGCACCGCTATATCTCCGACCGCTTCCTGCCCGACAAGGCGATCGACCTGATGGACGAGGCG
GCGAGCCGCATCCGCATGGAGGTCGAATCGAAGCCCGAGGAGATCGAGACGCTCGACCGCCGCATCATCCAGATGAAGAT
CGAGGAAGCCGCGCTCGGCAAGGAAAGCGACGCGGCGTCGAAGGACCGGCTCGCGAGCTTGCAGGCCGAGCTTGCCAATC
TCGAACAGCAGTCGGCCGAACTCACCCAGAAATGGCAGGCCGAAAAGGAGAAGATCCACGCCGAGGCGAAGATCAAGGAA
GAGCTCGACGCCGCGCGCTCGGCGCTTGAACAGGCGCAGCGCGCGGGCGACCTCGCGAAGGCGGGCGAGCTAAGCTATGG
CACCATCCCCGCGTTGGAAAAAAGACTTGCCGAGGCCGAGGCCGCATCGGGCAATGCAATGCTGCGCGAGGAAGTCACCG
CCGACGACATAGCAGCGGTGGTCAGCCGCTGGACCGGCATCCCCGTCGACCGGATGATGGAGGGCGAGCGCGAGAAGCTG
CTCAAGATGGAGGAGACGCTGACCCAGCGCGTGATCGGCCAGGACGAGGCCGTCCGCGCGGTCTCGACAGCGGTCCGCCG
CGCGCGCGCCGGGCTTCAGGACCCGAATCGCCCGCTCGGCAGCTTCCTCTTCCTCGGCCCCACGGGCGTCGGCAAGACCG
AGCTGACCAAGGCGCTCGCGCGCTTCCTGTTCGACGACGACAATGCGATGGTGCGCATCGACATGTCCGAATATATGGAA
AAGCACAGCGTCGCGCGGCTCGTCGGCGCGCCGCCGGGCTATGTCGGCTATGAGGAGGGCGGCACGCTCACCGAAGCGGT
GCGCCGCCGCCCCTATCAGGTCGTCCTCTTCGACGAGGTCGAAAAGGCGCATGGCGACGTGTTCAACATTCTGCTCCAGG
TGCTCGACGACGGGCGGCTCACCGACGGGCAGGGGCGGACGGTCGATTTCACCAACACGCTCATCATCCTGACCTCGAAC
CTCGGCAGCCAGGCGATCGCCGCGCTCCCCGATGGCGCCCCGGTCGAACAGGCCGAACCTGCCGTCATGGAGGTTGTGCG
CGCGCATTTCCGGCCCGAGTTCCTGAACCGGCTCGACGAGATCGTGCTCTTTCACCGTCTGGGGCAGGAACATATGGGCG
GCATCGTCGACATCCAGGTCGCGCGGGTGCAGAAGCTGCTCGACGACCGCAAGGTGACGCTCGACCTGACCGACGCAGCG
CGTGCCTGGCTCGGTCGCGTTGGCTATGACCCCGTCTATGGCGCGCGGCCGCTGAAGCGCGCGGTGCAGAAATATCTGCA
AGACCCGCTCGCCGATCTCATTCTGAAAGGCGAGGTCCGGGACGGCGCGACGATCAGGGTCGACGAGGGCGACGGCGGGT
TGATGCTGAGCACAGGCTGA

Upstream 100 bases:

>100_bases
GCCTTTATCGCTGTATCACCTTGCGAAGCAAAGCGTCGAGCCCTCTTGTGTTGCCAAAAAGCAACACTATCTTCGCTGGT
GAGAAAGGGGCTTATCCACC

Downstream 100 bases:

>100_bases
CGCTGCGCCAGCCTTCTTCGTTGATCGTCAGTTGCTGCCGTTGACGCGCGCGCGTCATCGCCTCGGCGGTGTCGCGCGCA
TTCTGGTTGCCCTGCGCCCA

Product: ATPase AAA-2

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 859; Mature: 859

Protein sequence:

>859_residues
MNLEKFTDRAKGFLQAAQTIAIRMNHQRISPEHIAKALLEDSQGMAAGLIANSGGDTARAVAGIDALLAKLPAVSGSGAQ
ATPGLDNDAVRLLDQAEQVAAKAGSEYVAVQNILLAMVLAPSTPVGKAFADAGVSADALNAAIAKLTGGRTADTASAEDR
YDALRKFARDLTEVAREGKLDPVIGRDEEIRRTVQILARRTKNNPVLIGEPGVGKTAIAEGLALRIVNGDVPDSLKDRRL
LALDMGALIAGAKYRGEFEERLKGVLDDVKAAEGEIILFIDEMHTLVGAGKSEGAMDASNLLKPALARGELHCIGATTLD
EYRKHVEKDPALQRRFQPVFVGEPTVEDSISILRGIKEKYELHHGVRITDGAIVAAATLSHRYISDRFLPDKAIDLMDEA
ASRIRMEVESKPEEIETLDRRIIQMKIEEAALGKESDAASKDRLASLQAELANLEQQSAELTQKWQAEKEKIHAEAKIKE
ELDAARSALEQAQRAGDLAKAGELSYGTIPALEKRLAEAEAASGNAMLREEVTADDIAAVVSRWTGIPVDRMMEGEREKL
LKMEETLTQRVIGQDEAVRAVSTAVRRARAGLQDPNRPLGSFLFLGPTGVGKTELTKALARFLFDDDNAMVRIDMSEYME
KHSVARLVGAPPGYVGYEEGGTLTEAVRRRPYQVVLFDEVEKAHGDVFNILLQVLDDGRLTDGQGRTVDFTNTLIILTSN
LGSQAIAALPDGAPVEQAEPAVMEVVRAHFRPEFLNRLDEIVLFHRLGQEHMGGIVDIQVARVQKLLDDRKVTLDLTDAA
RAWLGRVGYDPVYGARPLKRAVQKYLQDPLADLILKGEVRDGATIRVDEGDGGLMLSTG

Sequences:

>Translated_859_residues
MNLEKFTDRAKGFLQAAQTIAIRMNHQRISPEHIAKALLEDSQGMAAGLIANSGGDTARAVAGIDALLAKLPAVSGSGAQ
ATPGLDNDAVRLLDQAEQVAAKAGSEYVAVQNILLAMVLAPSTPVGKAFADAGVSADALNAAIAKLTGGRTADTASAEDR
YDALRKFARDLTEVAREGKLDPVIGRDEEIRRTVQILARRTKNNPVLIGEPGVGKTAIAEGLALRIVNGDVPDSLKDRRL
LALDMGALIAGAKYRGEFEERLKGVLDDVKAAEGEIILFIDEMHTLVGAGKSEGAMDASNLLKPALARGELHCIGATTLD
EYRKHVEKDPALQRRFQPVFVGEPTVEDSISILRGIKEKYELHHGVRITDGAIVAAATLSHRYISDRFLPDKAIDLMDEA
ASRIRMEVESKPEEIETLDRRIIQMKIEEAALGKESDAASKDRLASLQAELANLEQQSAELTQKWQAEKEKIHAEAKIKE
ELDAARSALEQAQRAGDLAKAGELSYGTIPALEKRLAEAEAASGNAMLREEVTADDIAAVVSRWTGIPVDRMMEGEREKL
LKMEETLTQRVIGQDEAVRAVSTAVRRARAGLQDPNRPLGSFLFLGPTGVGKTELTKALARFLFDDDNAMVRIDMSEYME
KHSVARLVGAPPGYVGYEEGGTLTEAVRRRPYQVVLFDEVEKAHGDVFNILLQVLDDGRLTDGQGRTVDFTNTLIILTSN
LGSQAIAALPDGAPVEQAEPAVMEVVRAHFRPEFLNRLDEIVLFHRLGQEHMGGIVDIQVARVQKLLDDRKVTLDLTDAA
RAWLGRVGYDPVYGARPLKRAVQKYLQDPLADLILKGEVRDGATIRVDEGDGGLMLSTG
>Mature_859_residues
MNLEKFTDRAKGFLQAAQTIAIRMNHQRISPEHIAKALLEDSQGMAAGLIANSGGDTARAVAGIDALLAKLPAVSGSGAQ
ATPGLDNDAVRLLDQAEQVAAKAGSEYVAVQNILLAMVLAPSTPVGKAFADAGVSADALNAAIAKLTGGRTADTASAEDR
YDALRKFARDLTEVAREGKLDPVIGRDEEIRRTVQILARRTKNNPVLIGEPGVGKTAIAEGLALRIVNGDVPDSLKDRRL
LALDMGALIAGAKYRGEFEERLKGVLDDVKAAEGEIILFIDEMHTLVGAGKSEGAMDASNLLKPALARGELHCIGATTLD
EYRKHVEKDPALQRRFQPVFVGEPTVEDSISILRGIKEKYELHHGVRITDGAIVAAATLSHRYISDRFLPDKAIDLMDEA
ASRIRMEVESKPEEIETLDRRIIQMKIEEAALGKESDAASKDRLASLQAELANLEQQSAELTQKWQAEKEKIHAEAKIKE
ELDAARSALEQAQRAGDLAKAGELSYGTIPALEKRLAEAEAASGNAMLREEVTADDIAAVVSRWTGIPVDRMMEGEREKL
LKMEETLTQRVIGQDEAVRAVSTAVRRARAGLQDPNRPLGSFLFLGPTGVGKTELTKALARFLFDDDNAMVRIDMSEYME
KHSVARLVGAPPGYVGYEEGGTLTEAVRRRPYQVVLFDEVEKAHGDVFNILLQVLDDGRLTDGQGRTVDFTNTLIILTSN
LGSQAIAALPDGAPVEQAEPAVMEVVRAHFRPEFLNRLDEIVLFHRLGQEHMGGIVDIQVARVQKLLDDRKVTLDLTDAA
RAWLGRVGYDPVYGARPLKRAVQKYLQDPLADLILKGEVRDGATIRVDEGDGGLMLSTG

Specific function: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE. Acts before DnaK, in the processing of protein aggregates. Protein binding stimulates the ATPase

COG id: COG0542

COG function: function code O; ATPases with chaperone activity, ATP-binding subunit

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the clpA/clpB family [H]

Homologues:

Organism=Homo sapiens, GI13540606, Length=420, Percent_Identity=33.5714285714286, Blast_Score=206, Evalue=9e-53,
Organism=Escherichia coli, GI1788943, Length=850, Percent_Identity=60.1176470588235, Blast_Score=1024, Evalue=0.0,
Organism=Escherichia coli, GI1787109, Length=319, Percent_Identity=44.2006269592476, Blast_Score=282, Evalue=5e-77,
Organism=Saccharomyces cerevisiae, GI6320464, Length=701, Percent_Identity=55.6348074179743, Blast_Score=797, Evalue=0.0,
Organism=Saccharomyces cerevisiae, GI6323002, Length=862, Percent_Identity=43.0394431554524, Blast_Score=678, Evalue=0.0,

Paralogues:

None

Copy number: 560 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR013093
- InterPro:   IPR003959
- InterPro:   IPR018368
- InterPro:   IPR017730
- InterPro:   IPR001270
- InterPro:   IPR019489
- InterPro:   IPR004176
- InterPro:   IPR023150 [H]

Pfam domain/function: PF00004 AAA; PF07724 AAA_2; PF02861 Clp_N; PF10431 ClpB_D2-small [H]

EC number: 3.4.21.92

Molecular weight: Translated: 93171; Mature: 93171

Theoretical pI: Translated: 5.01; Mature: 5.01

Prosite motif: PS00870 CLPAB_1 ; PS00871 CLPAB_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.1 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.1 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLEKFTDRAKGFLQAAQTIAIRMNHQRISPEHIAKALLEDSQGMAAGLIANSGGDTARA
CCHHHHHHHHHHHHHHHHHHHEEECCCCCCHHHHHHHHHHCCCCCEEEEEECCCCCHHHH
VAGIDALLAKLPAVSGSGAQATPGLDNDAVRLLDQAEQVAAKAGSEYVAVQNILLAMVLA
HHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHC
PSTPVGKAFADAGVSADALNAAIAKLTGGRTADTASAEDRYDALRKFARDLTEVAREGKL
CCCCCCHHHHHCCCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCC
DPVIGRDEEIRRTVQILARRTKNNPVLIGEPGVGKTAIAEGLALRIVNGDVPDSLKDRRL
CCCCCCCHHHHHHHHHHHHHCCCCCEEEECCCCCHHHHHCCCEEEEECCCCCCCHHCCEE
LALDMGALIAGAKYRGEFEERLKGVLDDVKAAEGEIILFIDEMHTLVGAGKSEGAMDASN
EEEEHHHHHHCCHHCCCHHHHHHHHHHHHHHCCCCEEEEEHHHHHHHCCCCCCCCCCHHH
LLKPALARGELHCIGATTLDEYRKHVEKDPALQRRFQPVFVGEPTVEDSISILRGIKEKY
HHHHHHHCCCEEEEECCHHHHHHHHHCCCHHHHHHCCCEECCCCCHHHHHHHHHHHHHHH
ELHHGVRITDGAIVAAATLSHRYISDRFLPDKAIDLMDEAASRIRMEVESKPEEIETLDR
HHHCCEEEECCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHH
RIIQMKIEEAALGKESDAASKDRLASLQAELANLEQQSAELTQKWQAEKEKIHAEAKIKE
HHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ELDAARSALEQAQRAGDLAKAGELSYGTIPALEKRLAEAEAASGNAMLREEVTADDIAAV
HHHHHHHHHHHHHHHCCHHHCCCCCCCCCHHHHHHHHHHHCCCCCCHHHHHCCHHHHHHH
VSRWTGIPVDRMMEGEREKLLKMEETLTQRVIGQDEAVRAVSTAVRRARAGLQDPNRPLG
HHHHCCCCHHHHHCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCCCCC
SFLFLGPTGVGKTELTKALARFLFDDDNAMVRIDMSEYMEKHSVARLVGAPPGYVGYEEG
CEEEECCCCCCHHHHHHHHHHHHCCCCCCEEEEEHHHHHHHHHHHHHHCCCCCCCCCCCC
GTLTEAVRRRPYQVVLFDEVEKAHGDVFNILLQVLDDGRLTDGQGRTVDFTNTLIILTSN
CHHHHHHHCCCCEEEEEHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEECCEEEEEECC
LGSQAIAALPDGAPVEQAEPAVMEVVRAHFRPEFLNRLDEIVLFHRLGQEHMGGIVDIQV
CCCHHHHCCCCCCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHCHHHCCCEEEEHH
ARVQKLLDDRKVTLDLTDAARAWLGRVGYDPVYGARPLKRAVQKYLQDPLADLILKGEVR
HHHHHHHCCCCEEEEEHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCHHHHHHCCCCCC
DGATIRVDEGDGGLMLSTG
CCCEEEEECCCCCEEEECC
>Mature Secondary Structure
MNLEKFTDRAKGFLQAAQTIAIRMNHQRISPEHIAKALLEDSQGMAAGLIANSGGDTARA
CCHHHHHHHHHHHHHHHHHHHEEECCCCCCHHHHHHHHHHCCCCCEEEEEECCCCCHHHH
VAGIDALLAKLPAVSGSGAQATPGLDNDAVRLLDQAEQVAAKAGSEYVAVQNILLAMVLA
HHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHC
PSTPVGKAFADAGVSADALNAAIAKLTGGRTADTASAEDRYDALRKFARDLTEVAREGKL
CCCCCCHHHHHCCCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCC
DPVIGRDEEIRRTVQILARRTKNNPVLIGEPGVGKTAIAEGLALRIVNGDVPDSLKDRRL
CCCCCCCHHHHHHHHHHHHHCCCCCEEEECCCCCHHHHHCCCEEEEECCCCCCCHHCCEE
LALDMGALIAGAKYRGEFEERLKGVLDDVKAAEGEIILFIDEMHTLVGAGKSEGAMDASN
EEEEHHHHHHCCHHCCCHHHHHHHHHHHHHHCCCCEEEEEHHHHHHHCCCCCCCCCCHHH
LLKPALARGELHCIGATTLDEYRKHVEKDPALQRRFQPVFVGEPTVEDSISILRGIKEKY
HHHHHHHCCCEEEEECCHHHHHHHHHCCCHHHHHHCCCEECCCCCHHHHHHHHHHHHHHH
ELHHGVRITDGAIVAAATLSHRYISDRFLPDKAIDLMDEAASRIRMEVESKPEEIETLDR
HHHCCEEEECCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHH
RIIQMKIEEAALGKESDAASKDRLASLQAELANLEQQSAELTQKWQAEKEKIHAEAKIKE
HHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ELDAARSALEQAQRAGDLAKAGELSYGTIPALEKRLAEAEAASGNAMLREEVTADDIAAV
HHHHHHHHHHHHHHHCCHHHCCCCCCCCCHHHHHHHHHHHCCCCCCHHHHHCCHHHHHHH
VSRWTGIPVDRMMEGEREKLLKMEETLTQRVIGQDEAVRAVSTAVRRARAGLQDPNRPLG
HHHHCCCCHHHHHCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCCCCC
SFLFLGPTGVGKTELTKALARFLFDDDNAMVRIDMSEYMEKHSVARLVGAPPGYVGYEEG
CEEEECCCCCCHHHHHHHHHHHHCCCCCCEEEEEHHHHHHHHHHHHHHCCCCCCCCCCCC
GTLTEAVRRRPYQVVLFDEVEKAHGDVFNILLQVLDDGRLTDGQGRTVDFTNTLIILTSN
CHHHHHHHCCCCEEEEEHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEECCEEEEEECC
LGSQAIAALPDGAPVEQAEPAVMEVVRAHFRPEFLNRLDEIVLFHRLGQEHMGGIVDIQV
CCCHHHHCCCCCCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHCHHHCCCEEEEHH
ARVQKLLDDRKVTLDLTDAARAWLGRVGYDPVYGARPLKRAVQKYLQDPLADLILKGEVR
HHHHHHHCCCCEEEEEHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCHHHHHHCCCCCC
DGATIRVDEGDGGLMLSTG
CCCEEEEECCCCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA