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The map label for this gene is cirA [H]

Identifier: 103487809

GI number: 103487809

Start: 2455375

End: 2457735

Strand: Direct

Name: cirA [H]

Synonym: Sala_2328

Alternate gene names: 103487809

Gene position: 2455375-2457735 (Clockwise)

Preceding gene: 103487808

Following gene: 103487811

Centisome position: 73.4

GC content: 64.13

Gene sequence:

>2361_bases
ATGAATGCACGGGCATCATTGCTCGCGGGCCTGTCTTCGCTTGCGCTTGTCGCGACCCCGGCCACGGCGCAGGACGCCGC
TGCCGAGGATGACGGCAACATCATCATCGTCACCGCGACGAAGCGCGACGCCAATCTTCAGGACATTCCCTTTTCGATCA
ACGCGCAAACCGCCGAGGACATCCAGAAATCGGGCGCGGTGACGCTCGAGGATCTGTCGCGCAACGTCGCGGGACTGTCG
GTCCAGAACCTCGGGCCGGGGCAGAGCCAGGTGTCGGTGCGCGGCGTGTCCGCCGGGCAGGTCGTGCGCGACCAGCCGGG
GGTCAAGGAACAGGTCGGCGTCTATCTCGACGAAAGCGTGATTTCGCTCTCGCTCTTCACCCCCGACATCGATCTTTACG
ACCTCAACCGCGTCGAAACGCTGCGCGGGCCGCAGGGCACGCTCTTCGGCTCGGGCTCGGTCGGCGGGACGATCCGCTAC
ATCACCAACCAGCCGAAGATCGGCGTGATGGAGGGCAGCGTCGAGGCGAATCTCAACCTCGTCGACGGTGACGACATCGG
CGGCCATCTGAAGGGCGCGGTCAATGTGCCGATGGGCGACAATGCGGCGCTGCGCGCGGTCGGCTATTACACACGCTACG
GCGGCTTCATCAACGCGATCGGTCCGGCGGGCAAGGAGGATGTCAACAGCGGCGAACGCTACGGTGGACGCATCGCGCTC
ACCTTCGAGCCCAGCGACAGCCTCTCGATCACCCCGCGCATCGTCTATCAGAAGGTCACGGCCGACGGCTTCAACCGGCA
GGAAATCTACAACCTCTACGCCAACCAGTTCACCACGACGCGCCCCGCGGTGACCTTTGACGAGCGCGAGCAATATCTGC
TGCTGCGCGAGGCGTTCGAGGATGAAACGCTGATCGCCGACCTCAAGATCGACGTCGGGCTGGGCGGCGCGACGCTGACC
TCGGTAACGAGCTATATCAACCGCGACATCCTCGTCAGCCGTGACGCGAGCGCGCTCACCGGATCGGTATCGGTCGACCT
TGGGTTCCCCGACGCGGGCGTGCTGCTGCCGTCGAACCTGCTCGACACCACCGACCTCGAAACCTGGACACAGGAGGTCC
GCGTTGCGTCGGACAATGACGGGCCGTTCCAGTGGCTCGTCGGCGGCTTCTATTCCAAGATCGACCGCGTCTATGCCCAG
CGGCTGCCGACGCCGGGCTATGATGCCGTCACCGATGCGACGCTTGGAGCCGGAACCTCGGCGGGCGCGCGCAACGGCTT
CGGCCCCGATTCGCCATATAACGCCGACCTGCCCTATGACATCAAGCAGTTCGCGATCTTCGGTGAGATCAGCTATGATT
TGAACGACGCCCTTACCGCGACGGCGGGCGGGCGCTATTATGACTTCAAGGAAACGCGCAGCTTCGTCTCCGGCGGCCTC
TTTGCCAACGGAGACAACCGCACCGACAGCACCAAGTCGAGCGGCTTCACCCCGCGTTTCCTGCTGTCCTACGACGTCAG
CGACAATGTCACGGTGAATGCCCAGGCGTCGAAGGGCTTTCGCCTCGGCGGGGTCAACGATCCCTTGAACCTGCCCCTCT
GCTCGCCGCAGGACGCAGCCTTGTTCGGCGCGTTTCAGGATTATGACGATGAAACATTGTGGAACTACGAACTCGGCGTG
AAGACGCAGGGGCGCGGTTTCACCTTCAACGCCGCGGGCTTTTACAACGACATCAAGAATCTCCAGGTCACGCTCGACGC
CGGCACCTGTTCGTCGCGCATCGTCTTCAACGTGCCCAAGGCGCATTCGATGGGCGTGGAGTTCGAACTGGGGCTGTCGC
CCGCCGACGGGCTCGACCTCAACCTGTCGGGCAGCCTCATCGAGGCCGAGTTCGACTCGACGCTGCCGGGCGCACTCACG
GTCGCGACGGGTATCCGCGACGGCAACCGCCTGCCGTCGGTGCCGAAGTTCCAGCTGACGGCATCGGGCAGTTATGAATG
GCCGATCGGTGACCGCGCGAACATGTATGTCGCGGCATCCTTCCAGCATGTCGGCACGCGCTACACCCAGCCGGCGGACC
AGGAAAACAACCCGCGCACCTTCGTCCACAACCTGCCCTTCGGCGGCGCCCCGGCCGGGGCATCGACGACGGTCGACCTG
CAACTGCCCGACTATCAACTCGTCAATCTGAGCGCGGGCGTCGATTTCGACAACGGCCTGTCGCTGATCGCCTATGTCAA
CAATGTCTTCGACGAAAACGCCCTGCTCTCGTTCGACCGCGAACGCGGCGGCCGCGCGCGGCTTGGCTACACTGTCGGCC
AGCCGCGCACCTTTGGCATCACCGCGCGCAAGACATTCTGA

Upstream 100 bases:

>100_bases
ATCGGTCGCGACCGATTCGTGCGCCATTGCGCAATTGCGACAAGAAGCGCACCTTCGCCGCCGGACCGACGCCAGATCGG
CCACCAGGAGGAGGATTATC

Downstream 100 bases:

>100_bases
CCGGCACAAGAGGGGGCGAACCGCAGCATCGGATCGCCCCCTTTCTCAACTGAAATGCTGCACAATTTTTGTGCAGCGTT
GCCGCAATTTTGGCCTTCCC

Product: TonB-dependent receptor

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 786; Mature: 786

Protein sequence:

>786_residues
MNARASLLAGLSSLALVATPATAQDAAAEDDGNIIIVTATKRDANLQDIPFSINAQTAEDIQKSGAVTLEDLSRNVAGLS
VQNLGPGQSQVSVRGVSAGQVVRDQPGVKEQVGVYLDESVISLSLFTPDIDLYDLNRVETLRGPQGTLFGSGSVGGTIRY
ITNQPKIGVMEGSVEANLNLVDGDDIGGHLKGAVNVPMGDNAALRAVGYYTRYGGFINAIGPAGKEDVNSGERYGGRIAL
TFEPSDSLSITPRIVYQKVTADGFNRQEIYNLYANQFTTTRPAVTFDEREQYLLLREAFEDETLIADLKIDVGLGGATLT
SVTSYINRDILVSRDASALTGSVSVDLGFPDAGVLLPSNLLDTTDLETWTQEVRVASDNDGPFQWLVGGFYSKIDRVYAQ
RLPTPGYDAVTDATLGAGTSAGARNGFGPDSPYNADLPYDIKQFAIFGEISYDLNDALTATAGGRYYDFKETRSFVSGGL
FANGDNRTDSTKSSGFTPRFLLSYDVSDNVTVNAQASKGFRLGGVNDPLNLPLCSPQDAALFGAFQDYDDETLWNYELGV
KTQGRGFTFNAAGFYNDIKNLQVTLDAGTCSSRIVFNVPKAHSMGVEFELGLSPADGLDLNLSGSLIEAEFDSTLPGALT
VATGIRDGNRLPSVPKFQLTASGSYEWPIGDRANMYVAASFQHVGTRYTQPADQENNPRTFVHNLPFGGAPAGASTTVDL
QLPDYQLVNLSAGVDFDNGLSLIAYVNNVFDENALLSFDRERGGRARLGYTVGQPRTFGITARKTF

Sequences:

>Translated_786_residues
MNARASLLAGLSSLALVATPATAQDAAAEDDGNIIIVTATKRDANLQDIPFSINAQTAEDIQKSGAVTLEDLSRNVAGLS
VQNLGPGQSQVSVRGVSAGQVVRDQPGVKEQVGVYLDESVISLSLFTPDIDLYDLNRVETLRGPQGTLFGSGSVGGTIRY
ITNQPKIGVMEGSVEANLNLVDGDDIGGHLKGAVNVPMGDNAALRAVGYYTRYGGFINAIGPAGKEDVNSGERYGGRIAL
TFEPSDSLSITPRIVYQKVTADGFNRQEIYNLYANQFTTTRPAVTFDEREQYLLLREAFEDETLIADLKIDVGLGGATLT
SVTSYINRDILVSRDASALTGSVSVDLGFPDAGVLLPSNLLDTTDLETWTQEVRVASDNDGPFQWLVGGFYSKIDRVYAQ
RLPTPGYDAVTDATLGAGTSAGARNGFGPDSPYNADLPYDIKQFAIFGEISYDLNDALTATAGGRYYDFKETRSFVSGGL
FANGDNRTDSTKSSGFTPRFLLSYDVSDNVTVNAQASKGFRLGGVNDPLNLPLCSPQDAALFGAFQDYDDETLWNYELGV
KTQGRGFTFNAAGFYNDIKNLQVTLDAGTCSSRIVFNVPKAHSMGVEFELGLSPADGLDLNLSGSLIEAEFDSTLPGALT
VATGIRDGNRLPSVPKFQLTASGSYEWPIGDRANMYVAASFQHVGTRYTQPADQENNPRTFVHNLPFGGAPAGASTTVDL
QLPDYQLVNLSAGVDFDNGLSLIAYVNNVFDENALLSFDRERGGRARLGYTVGQPRTFGITARKTF
>Mature_786_residues
MNARASLLAGLSSLALVATPATAQDAAAEDDGNIIIVTATKRDANLQDIPFSINAQTAEDIQKSGAVTLEDLSRNVAGLS
VQNLGPGQSQVSVRGVSAGQVVRDQPGVKEQVGVYLDESVISLSLFTPDIDLYDLNRVETLRGPQGTLFGSGSVGGTIRY
ITNQPKIGVMEGSVEANLNLVDGDDIGGHLKGAVNVPMGDNAALRAVGYYTRYGGFINAIGPAGKEDVNSGERYGGRIAL
TFEPSDSLSITPRIVYQKVTADGFNRQEIYNLYANQFTTTRPAVTFDEREQYLLLREAFEDETLIADLKIDVGLGGATLT
SVTSYINRDILVSRDASALTGSVSVDLGFPDAGVLLPSNLLDTTDLETWTQEVRVASDNDGPFQWLVGGFYSKIDRVYAQ
RLPTPGYDAVTDATLGAGTSAGARNGFGPDSPYNADLPYDIKQFAIFGEISYDLNDALTATAGGRYYDFKETRSFVSGGL
FANGDNRTDSTKSSGFTPRFLLSYDVSDNVTVNAQASKGFRLGGVNDPLNLPLCSPQDAALFGAFQDYDDETLWNYELGV
KTQGRGFTFNAAGFYNDIKNLQVTLDAGTCSSRIVFNVPKAHSMGVEFELGLSPADGLDLNLSGSLIEAEFDSTLPGALT
VATGIRDGNRLPSVPKFQLTASGSYEWPIGDRANMYVAASFQHVGTRYTQPADQENNPRTFVHNLPFGGAPAGASTTVDL
QLPDYQLVNLSAGVDFDNGLSLIAYVNNVFDENALLSFDRERGGRARLGYTVGQPRTFGITARKTF

Specific function: Not yet known. Postulated to participate in iron transport. Outer membrane receptor for colicins IA and IB [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell outer membrane [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tonB-dependent receptor family [H]

Homologues:

Organism=Escherichia coli, GI1788478, Length=182, Percent_Identity=30.2197802197802, Blast_Score=77, Evalue=5e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012910
- InterPro:   IPR000531
- InterPro:   IPR010916
- InterPro:   IPR010917 [H]

Pfam domain/function: PF07715 Plug; PF00593 TonB_dep_Rec [H]

EC number: NA

Molecular weight: Translated: 84118; Mature: 84118

Theoretical pI: Translated: 4.28; Mature: 4.28

Prosite motif: PS00761 SPASE_I_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
0.6 %Met     (Translated Protein)
0.9 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
0.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNARASLLAGLSSLALVATPATAQDAAAEDDGNIIIVTATKRDANLQDIPFSINAQTAED
CCCHHHHHHHHHHEEEEECCCCCCCCCCCCCCCEEEEEECCCCCCCCCCCEEECCCCHHH
IQKSGAVTLEDLSRNVAGLSVQNLGPGQSQVSVRGVSAGQVVRDQPGVKEQVGVYLDESV
HHHCCCEEHHHHCCCCCCEEEECCCCCCCEEEEEECCCCCEECCCCCCHHHHCEEEECCE
ISLSLFTPDIDLYDLNRVETLRGPQGTLFGSGSVGGTIRYITNQPKIGVMEGSVEANLNL
EEEEEECCCCCEEECCCHHCCCCCCCEEEECCCCCCEEEEEECCCCEEEEECCCEEEEEE
VDGDDIGGHLKGAVNVPMGDNAALRAVGYYTRYGGFINAIGPAGKEDVNSGERYGGRIAL
ECCCCCCCCCCEEEECCCCCCCCEEEEEHHHHHCCCEECCCCCCCCCCCCCHHCCCEEEE
TFEPSDSLSITPRIVYQKVTADGFNRQEIYNLYANQFTTTRPAVTFDEREQYLLLREAFE
EECCCCCCEECCEEEEEEECCCCCCHHHHHHHHHHCEECCCCCEEECCCHHEEHHHHHCC
DETLIADLKIDVGLGGATLTSVTSYINRDILVSRDASALTGSVSVDLGFPDAGVLLPSNL
CCEEEEEEEEEECCCCHHHHHHHHHHCCCEEEECCCCCEEEEEEEEECCCCCCEECCCCC
LDTTDLETWTQEVRVASDNDGPFQWLVGGFYSKIDRVYAQRLPTPGYDAVTDATLGAGTS
CCCCCHHHHHHHEEEECCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHCCCCCCCCCC
AGARNGFGPDSPYNADLPYDIKQFAIFGEISYDLNDALTATAGGRYYDFKETRSFVSGGL
CCCCCCCCCCCCCCCCCCCCCEEEEEEEEEEECCCCCEEECCCCEEEEHHHHHHHHCCCE
FANGDNRTDSTKSSGFTPRFLLSYDVSDNVTVNAQASKGFRLGGVNDPLNLPLCSPQDAA
EECCCCCCCCCCCCCCCEEEEEEECCCCCEEEEEECCCCEEECCCCCCCCCCCCCCCCCE
LFGAFQDYDDETLWNYELGVKTQGRGFTFNAAGFYNDIKNLQVTLDAGTCSSRIVFNVPK
EEECHHCCCCCEEEEEEECEEECCCCEEEECCHHHCCCCCEEEEEECCCCCCEEEEECCC
AHSMGVEFELGLSPADGLDLNLSGSLIEAEFDSTLPGALTVATGIRDGNRLPSVPKFQLT
CCCCCEEEEECCCCCCCEEEECCCCEEEEECCCCCCCEEEEEECCCCCCCCCCCCCEEEE
ASGSYEWPIGDRANMYVAASFQHVGTRYTQPADQENNPRTFVHNLPFGGAPAGASTTVDL
ECCCCCCCCCCCCCEEEEEEHHHCCCCCCCCCCCCCCCCEEEEECCCCCCCCCCCEEEEE
QLPDYQLVNLSAGVDFDNGLSLIAYVNNVFDENALLSFDRERGGRARLGYTVGQPRTFGI
ECCCEEEEEEECCCCCCCCCCCEEHHHHHCCCCCEEEEHHCCCCCEEEEEECCCCEEEEE
TARKTF
EEECCC
>Mature Secondary Structure
MNARASLLAGLSSLALVATPATAQDAAAEDDGNIIIVTATKRDANLQDIPFSINAQTAED
CCCHHHHHHHHHHEEEEECCCCCCCCCCCCCCCEEEEEECCCCCCCCCCCEEECCCCHHH
IQKSGAVTLEDLSRNVAGLSVQNLGPGQSQVSVRGVSAGQVVRDQPGVKEQVGVYLDESV
HHHCCCEEHHHHCCCCCCEEEECCCCCCCEEEEEECCCCCEECCCCCCHHHHCEEEECCE
ISLSLFTPDIDLYDLNRVETLRGPQGTLFGSGSVGGTIRYITNQPKIGVMEGSVEANLNL
EEEEEECCCCCEEECCCHHCCCCCCCEEEECCCCCCEEEEEECCCCEEEEECCCEEEEEE
VDGDDIGGHLKGAVNVPMGDNAALRAVGYYTRYGGFINAIGPAGKEDVNSGERYGGRIAL
ECCCCCCCCCCEEEECCCCCCCCEEEEEHHHHHCCCEECCCCCCCCCCCCCHHCCCEEEE
TFEPSDSLSITPRIVYQKVTADGFNRQEIYNLYANQFTTTRPAVTFDEREQYLLLREAFE
EECCCCCCEECCEEEEEEECCCCCCHHHHHHHHHHCEECCCCCEEECCCHHEEHHHHHCC
DETLIADLKIDVGLGGATLTSVTSYINRDILVSRDASALTGSVSVDLGFPDAGVLLPSNL
CCEEEEEEEEEECCCCHHHHHHHHHHCCCEEEECCCCCEEEEEEEEECCCCCCEECCCCC
LDTTDLETWTQEVRVASDNDGPFQWLVGGFYSKIDRVYAQRLPTPGYDAVTDATLGAGTS
CCCCCHHHHHHHEEEECCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHCCCCCCCCCC
AGARNGFGPDSPYNADLPYDIKQFAIFGEISYDLNDALTATAGGRYYDFKETRSFVSGGL
CCCCCCCCCCCCCCCCCCCCCEEEEEEEEEEECCCCCEEECCCCEEEEHHHHHHHHCCCE
FANGDNRTDSTKSSGFTPRFLLSYDVSDNVTVNAQASKGFRLGGVNDPLNLPLCSPQDAA
EECCCCCCCCCCCCCCCEEEEEEECCCCCEEEEEECCCCEEECCCCCCCCCCCCCCCCCE
LFGAFQDYDDETLWNYELGVKTQGRGFTFNAAGFYNDIKNLQVTLDAGTCSSRIVFNVPK
EEECHHCCCCCEEEEEEECEEECCCCEEEECCHHHCCCCCEEEEEECCCCCCEEEEECCC
AHSMGVEFELGLSPADGLDLNLSGSLIEAEFDSTLPGALTVATGIRDGNRLPSVPKFQLT
CCCCCEEEEECCCCCCCEEEECCCCEEEEECCCCCCCEEEEEECCCCCCCCCCCCCEEEE
ASGSYEWPIGDRANMYVAASFQHVGTRYTQPADQENNPRTFVHNLPFGGAPAGASTTVDL
ECCCCCCCCCCCCCEEEEEEHHHCCCCCCCCCCCCCCCCEEEEECCCCCCCCCCCEEEEE
QLPDYQLVNLSAGVDFDNGLSLIAYVNNVFDENALLSFDRERGGRARLGYTVGQPRTFGI
ECCCEEEEEEECCCCCCCCCCCEEHHHHHCCCCCEEEEHHCCCCCEEEEEECCCCEEEEE
TARKTF
EEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2644220; 9278503; 3316180; 1315732; 2160948 [H]