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The map label for this gene is tsf

Identifier: 103487443

GI number: 103487443

Start: 2065409

End: 2066335

Strand: Reverse

Name: tsf

Synonym: Sala_1959

Alternate gene names: 103487443

Gene position: 2066335-2065409 (Counterclockwise)

Preceding gene: 103487444

Following gene: 103487442

Centisome position: 61.77

GC content: 67.1

Gene sequence:

>927_bases
ATGGCTGAAATCACGGCCGCCCTCGTCAAGGAACTGCGCGACCGCACCGGCGCGGGCATGATGGACTGCAAGAAGGCGCT
CGCCGAGAACAACGGCGACATCGAGGCGTCGATCGACTGGCTGCGCACCAAGGGCCTTGCCGCCGCCGCCAAAAAGGCCG
GCCGCGTCGCCGCCGAAGGCCTGGTCGGTTTCGCGACCGACGGCACCAGGGGCGCGCTCGTCGAAGTGAACAGCGAAACC
GACTTCGTCGGCAAGAATGAGCAATTCCAGGCGTTCGTTCGCGACGTGACGCAGGTTGCGCTCGCGGAGGGCATCACCGA
CATCGACGCGCTCGCCGCCGCACCCTATCCGACCGGGGGCACCGTTGCCGAACAGCTGACCAGCAACATCGCGACGATCG
GCGAAAACCAGTCGTTGCGCCGCGTCGCCCTGCTGACGGTGAACTCGGGCGCCGTGACCGGCTATGTCCACAACGCCGCC
GCGCCCGGCATGGGCAAGATCGGCGTGCTCGTCGCGCTCGAATCGAGCGCCGGTGCCGACGTGCTCGAACCGCTCGGCAA
GCAGCTGGCTATGCACGTCGCCGCCGCAAACCCGCTGGCGCTGAACGGCGATGACCTCGACGCCGACCTCGTCGCGCGCG
AACGCGCGATCGCCGAGGAAAAGGCCGCCCAGTCGGGCAAGCCGGCCGAGATCGTCGCCAAGATGGTCGATGGAGCGATT
GCCAAGTTCCGCAAGGAAAATGCGCTGTTGTCGCAGCTGTTCGTGATGGACGGCAAGACGCCGGTCGCCGAAGTCGTCGC
CGCCGCCGGCAAGGATGTCGGCGCCGCGATAACGCTCAAGGGCTTCGTCCGCTTCCAGCTCGGTGAAGGCATCGAGAAGG
AAGAAAGCGATTTCGCGGCGGAAGTCGCGGCTGCCGCCGGCGTCTAA

Upstream 100 bases:

>100_bases
CGGTCCGGCGCCGTCCCCGTCATCGGTTTGACTTATCGCGCCGCCACGCGCGGCGAATGCAGGCCCCAGCGAGCCTGCCC
CTTTTGGAAAGGATTATGAC

Downstream 100 bases:

>100_bases
AAGAGAAGATACGGATTGCCGCGTCGGTCGCGGCAGTCCGCTTGGCAATGGCGCGCACCCGCTCTAGGGTGCGCGCCATT
CGCTTATATCGAGTTTGCAA

Product: elongation factor Ts

Products: NA

Alternate protein names: EF-Ts

Number of amino acids: Translated: 308; Mature: 307

Protein sequence:

>308_residues
MAEITAALVKELRDRTGAGMMDCKKALAENNGDIEASIDWLRTKGLAAAAKKAGRVAAEGLVGFATDGTRGALVEVNSET
DFVGKNEQFQAFVRDVTQVALAEGITDIDALAAAPYPTGGTVAEQLTSNIATIGENQSLRRVALLTVNSGAVTGYVHNAA
APGMGKIGVLVALESSAGADVLEPLGKQLAMHVAAANPLALNGDDLDADLVARERAIAEEKAAQSGKPAEIVAKMVDGAI
AKFRKENALLSQLFVMDGKTPVAEVVAAAGKDVGAAITLKGFVRFQLGEGIEKEESDFAAEVAAAAGV

Sequences:

>Translated_308_residues
MAEITAALVKELRDRTGAGMMDCKKALAENNGDIEASIDWLRTKGLAAAAKKAGRVAAEGLVGFATDGTRGALVEVNSET
DFVGKNEQFQAFVRDVTQVALAEGITDIDALAAAPYPTGGTVAEQLTSNIATIGENQSLRRVALLTVNSGAVTGYVHNAA
APGMGKIGVLVALESSAGADVLEPLGKQLAMHVAAANPLALNGDDLDADLVARERAIAEEKAAQSGKPAEIVAKMVDGAI
AKFRKENALLSQLFVMDGKTPVAEVVAAAGKDVGAAITLKGFVRFQLGEGIEKEESDFAAEVAAAAGV
>Mature_307_residues
AEITAALVKELRDRTGAGMMDCKKALAENNGDIEASIDWLRTKGLAAAAKKAGRVAAEGLVGFATDGTRGALVEVNSETD
FVGKNEQFQAFVRDVTQVALAEGITDIDALAAAPYPTGGTVAEQLTSNIATIGENQSLRRVALLTVNSGAVTGYVHNAAA
PGMGKIGVLVALESSAGADVLEPLGKQLAMHVAAANPLALNGDDLDADLVARERAIAEEKAAQSGKPAEIVAKMVDGAIA
KFRKENALLSQLFVMDGKTPVAEVVAAAGKDVGAAITLKGFVRFQLGEGIEKEESDFAAEVAAAAGV

Specific function: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome

COG id: COG0264

COG function: function code J; Translation elongation factor Ts

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the EF-Ts family

Homologues:

Organism=Homo sapiens, GI171846268, Length=225, Percent_Identity=35.5555555555556, Blast_Score=116, Evalue=2e-26,
Organism=Homo sapiens, GI291084500, Length=246, Percent_Identity=34.1463414634146, Blast_Score=111, Evalue=1e-24,
Organism=Homo sapiens, GI291084502, Length=93, Percent_Identity=43.010752688172, Blast_Score=79, Evalue=4e-15,
Organism=Homo sapiens, GI291084498, Length=93, Percent_Identity=43.010752688172, Blast_Score=79, Evalue=6e-15,
Organism=Escherichia coli, GI1786366, Length=305, Percent_Identity=49.1803278688525, Blast_Score=238, Evalue=3e-64,
Organism=Caenorhabditis elegans, GI17561440, Length=301, Percent_Identity=27.2425249169435, Blast_Score=91, Evalue=6e-19,
Organism=Drosophila melanogaster, GI19921466, Length=307, Percent_Identity=28.3387622149837, Blast_Score=103, Evalue=2e-22,

Paralogues:

None

Copy number: 2670 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1100 Molecules/Cell In: Stationary-Phase, Rich-Media (Based on E. coli). 4173 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 14563 Molecules/Cell In: Growth Phase, Gluco

Swissprot (AC and ID): EFTS_SPHAL (Q1GRQ1)

Other databases:

- EMBL:   CP000356
- RefSeq:   YP_617004.1
- ProteinModelPortal:   Q1GRQ1
- SMR:   Q1GRQ1
- GeneID:   4080508
- GenomeReviews:   CP000356_GR
- KEGG:   sal:Sala_1959
- NMPDR:   fig|317655.9.peg.1890
- HOGENOM:   HBG713289
- OMA:   YLHGTRI
- ProtClustDB:   PRK09377
- BioCyc:   SALA317655:SALA_1959-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00050
- InterPro:   IPR001816
- InterPro:   IPR014039
- InterPro:   IPR018101
- InterPro:   IPR009060
- InterPro:   IPR000449
- Gene3D:   G3DSA:3.30.479.20
- PANTHER:   PTHR11741
- TIGRFAMs:   TIGR00116

Pfam domain/function: PF00889 EF_TS; PF00627 UBA; SSF54713 EF_TS; SSF46934 UBA_like

EC number: NA

Molecular weight: Translated: 31585; Mature: 31454

Theoretical pI: Translated: 4.53; Mature: 4.53

Prosite motif: PS01126 EF_TS_1; PS01127 EF_TS_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAEITAALVKELRDRTGAGMMDCKKALAENNGDIEASIDWLRTKGLAAAAKKAGRVAAEG
CCHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCEEEHHHHHHHCCHHHHHHHHCCHHHHC
LVGFATDGTRGALVEVNSETDFVGKNEQFQAFVRDVTQVALAEGITDIDALAAAPYPTGG
CEEEECCCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCCCCC
TVAEQLTSNIATIGENQSLRRVALLTVNSGAVTGYVHNAAAPGMGKIGVLVALESSAGAD
HHHHHHHHHHHHCCCCCCCEEEEEEEECCCCEEEEEECCCCCCCCCEEEEEEECCCCCCH
VLEPLGKQLAMHVAAANPLALNGDDLDADLVARERAIAEEKAAQSGKPAEIVAKMVDGAI
HHHHHHHHHHHHHHCCCCEEECCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHH
AKFRKENALLSQLFVMDGKTPVAEVVAAAGKDVGAAITLKGFVRFQLGEGIEKEESDFAA
HHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCEEEEEEHHEEEECCCCCCCHHHHHHH
EVAAAAGV
HHHHHCCC
>Mature Secondary Structure 
AEITAALVKELRDRTGAGMMDCKKALAENNGDIEASIDWLRTKGLAAAAKKAGRVAAEG
CHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCEEEHHHHHHHCCHHHHHHHHCCHHHHC
LVGFATDGTRGALVEVNSETDFVGKNEQFQAFVRDVTQVALAEGITDIDALAAAPYPTGG
CEEEECCCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCCCCC
TVAEQLTSNIATIGENQSLRRVALLTVNSGAVTGYVHNAAAPGMGKIGVLVALESSAGAD
HHHHHHHHHHHHCCCCCCCEEEEEEEECCCCEEEEEECCCCCCCCCEEEEEEECCCCCCH
VLEPLGKQLAMHVAAANPLALNGDDLDADLVARERAIAEEKAAQSGKPAEIVAKMVDGAI
HHHHHHHHHHHHHHCCCCEEECCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHH
AKFRKENALLSQLFVMDGKTPVAEVVAAAGKDVGAAITLKGFVRFQLGEGIEKEESDFAA
HHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCEEEEEEHHEEEECCCCCCCHHHHHHH
EVAAAAGV
HHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA