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The map label for this gene is frr

Identifier: 103487441

GI number: 103487441

Start: 2063871

End: 2064425

Strand: Reverse

Name: frr

Synonym: Sala_1957

Alternate gene names: 103487441

Gene position: 2064425-2063871 (Counterclockwise)

Preceding gene: 103487442

Following gene: 103487440

Centisome position: 61.71

GC content: 63.42

Gene sequence:

>555_bases
ATGGCGAAATATGACAAGGCCGACCTTGAACGCCGGATGCACGGCGCCGTTGAATCGCTGAAGCACGACCTGGCCGGATT
GCGCACCGGCCGTGCCAATGCGGCGCTGCTCGATCCGGTGACGGTGGAGGTTTACGGCAGCCAGATGCCGCTCAACCAGA
TCGCGTCGATCAGCGTGCCCGAACCGCGGATGCTGTCGGTGCAGGTGTGGGACAAGGCGAACGTCGGCCCGGTCGACAAG
GCGATCCGTTCGGCGGGACTCGGCCTCAATCCGATCGTCGATGGCCAGATGCTGCGTCTGCCGATCCCCGAGATGACGCA
GGAGCGCCGCAAGGAACTGTCGAAGCTTGCCGGCCAATATGCCGAAAAGGCGCGCGTTGCGGTGCGCAACGTCCGCCGCG
ACGGCATGGACAATCTGAAGCAGGACGAAAACAAGAAGGAAATCAGCGAGGACGAACGCAAGCGCCACGAGACCGAGGTG
CAGAAGCTGACCGATGCGACGATCGCCGAGATCGACGCCGCGGCGACGGCGAAGGAAAAGGAAATCCTGGGCTAG

Upstream 100 bases:

>100_bases
CGTCGAGCGAAGTCGAGACGCCCATAAGGCGCGTGCTACCGATGGGCATCTCGACTTCGCTCGATGCGAACGGGTGTGGG
GAATAGAGAGGAAAAGACAG

Downstream 100 bases:

>100_bases
TGCTTTGGGGCGCCTATCTCTCTTCCGCTCGTGTCGAGCGAAGTCGAGACACCCATCGGACTGGAACACGGCCGAGGGGC
ATCTCGACTTCGCTCGATGC

Product: ribosome recycling factor

Products: NA

Alternate protein names: RRF; Ribosome-releasing factor

Number of amino acids: Translated: 184; Mature: 183

Protein sequence:

>184_residues
MAKYDKADLERRMHGAVESLKHDLAGLRTGRANAALLDPVTVEVYGSQMPLNQIASISVPEPRMLSVQVWDKANVGPVDK
AIRSAGLGLNPIVDGQMLRLPIPEMTQERRKELSKLAGQYAEKARVAVRNVRRDGMDNLKQDENKKEISEDERKRHETEV
QKLTDATIAEIDAAATAKEKEILG

Sequences:

>Translated_184_residues
MAKYDKADLERRMHGAVESLKHDLAGLRTGRANAALLDPVTVEVYGSQMPLNQIASISVPEPRMLSVQVWDKANVGPVDK
AIRSAGLGLNPIVDGQMLRLPIPEMTQERRKELSKLAGQYAEKARVAVRNVRRDGMDNLKQDENKKEISEDERKRHETEV
QKLTDATIAEIDAAATAKEKEILG
>Mature_183_residues
AKYDKADLERRMHGAVESLKHDLAGLRTGRANAALLDPVTVEVYGSQMPLNQIASISVPEPRMLSVQVWDKANVGPVDKA
IRSAGLGLNPIVDGQMLRLPIPEMTQERRKELSKLAGQYAEKARVAVRNVRRDGMDNLKQDENKKEISEDERKRHETEVQ
KLTDATIAEIDAAATAKEKEILG

Specific function: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another

COG id: COG0233

COG function: function code J; Ribosome recycling factor

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RRF family

Homologues:

Organism=Homo sapiens, GI20270317, Length=174, Percent_Identity=35.0574712643678, Blast_Score=106, Evalue=2e-23,
Organism=Homo sapiens, GI291042689, Length=178, Percent_Identity=34.8314606741573, Blast_Score=101, Evalue=3e-22,
Organism=Escherichia coli, GI1786368, Length=178, Percent_Identity=47.752808988764, Blast_Score=163, Evalue=5e-42,
Organism=Drosophila melanogaster, GI24661488, Length=177, Percent_Identity=31.638418079096, Blast_Score=84, Evalue=5e-17,

Paralogues:

None

Copy number: 840 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): RRF_SPHAL (Q1GRQ3)

Other databases:

- EMBL:   CP000356
- RefSeq:   YP_617002.1
- ProteinModelPortal:   Q1GRQ3
- SMR:   Q1GRQ3
- GeneID:   4080506
- GenomeReviews:   CP000356_GR
- KEGG:   sal:Sala_1957
- NMPDR:   fig|317655.9.peg.1888
- HOGENOM:   HBG533975
- OMA:   YYGAETP
- ProtClustDB:   PRK00083
- BioCyc:   SALA317655:SALA_1957-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00040
- InterPro:   IPR002661
- InterPro:   IPR015998
- PANTHER:   PTHR20982
- PANTHER:   PTHR20982:SF3
- TIGRFAMs:   TIGR00496

Pfam domain/function: PF01765 RRF; SSF55194 Ribosome_recyc_fac

EC number: NA

Molecular weight: Translated: 20436; Mature: 20304

Theoretical pI: Translated: 7.77; Mature: 7.77

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKYDKADLERRMHGAVESLKHDLAGLRTGRANAALLDPVTVEVYGSQMPLNQIASISVP
CCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCEEEEEECCCCCHHHHHCCCCC
EPRMLSVQVWDKANVGPVDKAIRSAGLGLNPIVDGQMLRLPIPEMTQERRKELSKLAGQY
CCCEEEEEECCCCCCCHHHHHHHHCCCCCCCCCCCCEEECCCHHHHHHHHHHHHHHHHHH
AEKARVAVRNVRRDGMDNLKQDENKKEISEDERKRHETEVQKLTDATIAEIDAAATAKEK
HHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EILG
HCCC
>Mature Secondary Structure 
AKYDKADLERRMHGAVESLKHDLAGLRTGRANAALLDPVTVEVYGSQMPLNQIASISVP
CCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCEEEEEECCCCCHHHHHCCCCC
EPRMLSVQVWDKANVGPVDKAIRSAGLGLNPIVDGQMLRLPIPEMTQERRKELSKLAGQY
CCCEEEEEECCCCCCCHHHHHHHHCCCCCCCCCCCCEEECCCHHHHHHHHHHHHHHHHHH
AEKARVAVRNVRRDGMDNLKQDENKKEISEDERKRHETEVQKLTDATIAEIDAAATAKEK
HHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EILG
HCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA