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The map label for this gene is ampR [H]

Identifier: 103487387

GI number: 103487387

Start: 2001751

End: 2002629

Strand: Reverse

Name: ampR [H]

Synonym: Sala_1903

Alternate gene names: 103487387

Gene position: 2002629-2001751 (Counterclockwise)

Preceding gene: 103487389

Following gene: 103487382

Centisome position: 59.87

GC content: 69.17

Gene sequence:

>879_bases
ATGGACCGCGCGCAGCTTCCCCTCAATGCCCTCCGCGCTTTCGAGGCTGCGGCGCGCCATCTCAATTTCACGCGCGCGGG
ATTGGAACTCTGCGTCAGCCAGGGGGCGGTGAGCCATCAGGTCGCCGCGCTCGAGCGCCGCCTTGGCACGCGGCTGTTTC
ACCGCCTTCCGCGCGGGCTGGCCCTGACCGACGAAGGCCATGCGCTTGTCCCCGTGGTGTCGGAGGCGTTCGACCGTGTC
GCCGCAACGCTTGACCAATATGCCGATGGCCGCTTTCGCGAGACACTGAAGGTCGGGGTGGTCGGCACCTTTGCGACCGG
CTGGCTGATGCCACGGCTTGACGCCTTTTCGCGCGCGCATCCGTCGATCGACCTGCGTATTGCGACAAACAACAACCGGG
TCGACCTTGCGGGCGAGGGGCTCGACTATGCGATCCGCTTCGGCGACGGCGCATGGCACGGCACCCACGCCGAACCTTTG
CTTGATGCGCCGATGGCGCCGATCTGCGCGCCGGTGGTCGCGGCGCGGCTCAGGACGCCCGCCGATCTTGCGTCCGAGCG
GCTGCTTCGATCCTATCGCGCCGACGAATGGGCGCTCTGGTTCGGTGCGGCGGGCATCGCCGCGCCGGTAATGCGCGGTC
CGGTCTTCGACAGCTCGGCGCTGATGGCGGCGGCTGCGGCGGCGGGGCAGGGGGTGGCGCTTGCGCCGCCGTCGATGTTC
ACGCGCGAACTTGCCGCCGAGTTGCTTGTCCAGCCGTTCGCCATCGCGGTCGACACGGGGCGCTACTGGCTGACGCGGCT
GATGTCGCGCGCCGAGAGTGAGGGGATGCTTCGCTTTCGCGCATGGCTGTTCGCCGAGGTGGCAGCGGCGGGCGCATGA

Upstream 100 bases:

>100_bases
ATCATCATCATCTCCTTTCGTCATCGAAAATGCCCGTTCGCCCTCCGTGCGACAAAGCATCATTTCTCGACAAAGCCATG
AGAATAATTGATGATAAGCC

Downstream 100 bases:

>100_bases
AGCGCCGCGCGCCATAGCAAAAGGGCCGCGCTTCCCTTTCGGAAAACGCGGCCCTTTCAAAAGGCCTTTCAGGAAACTTA
AGCTTCCTTGGCGTCGTCCG

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 292; Mature: 292

Protein sequence:

>292_residues
MDRAQLPLNALRAFEAAARHLNFTRAGLELCVSQGAVSHQVAALERRLGTRLFHRLPRGLALTDEGHALVPVVSEAFDRV
AATLDQYADGRFRETLKVGVVGTFATGWLMPRLDAFSRAHPSIDLRIATNNNRVDLAGEGLDYAIRFGDGAWHGTHAEPL
LDAPMAPICAPVVAARLRTPADLASERLLRSYRADEWALWFGAAGIAAPVMRGPVFDSSALMAAAAAAGQGVALAPPSMF
TRELAAELLVQPFAIAVDTGRYWLTRLMSRAESEGMLRFRAWLFAEVAAAGA

Sequences:

>Translated_292_residues
MDRAQLPLNALRAFEAAARHLNFTRAGLELCVSQGAVSHQVAALERRLGTRLFHRLPRGLALTDEGHALVPVVSEAFDRV
AATLDQYADGRFRETLKVGVVGTFATGWLMPRLDAFSRAHPSIDLRIATNNNRVDLAGEGLDYAIRFGDGAWHGTHAEPL
LDAPMAPICAPVVAARLRTPADLASERLLRSYRADEWALWFGAAGIAAPVMRGPVFDSSALMAAAAAAGQGVALAPPSMF
TRELAAELLVQPFAIAVDTGRYWLTRLMSRAESEGMLRFRAWLFAEVAAAGA
>Mature_292_residues
MDRAQLPLNALRAFEAAARHLNFTRAGLELCVSQGAVSHQVAALERRLGTRLFHRLPRGLALTDEGHALVPVVSEAFDRV
AATLDQYADGRFRETLKVGVVGTFATGWLMPRLDAFSRAHPSIDLRIATNNNRVDLAGEGLDYAIRFGDGAWHGTHAEPL
LDAPMAPICAPVVAARLRTPADLASERLLRSYRADEWALWFGAAGIAAPVMRGPVFDSSALMAAAAAAGQGVALAPPSMF
TRELAAELLVQPFAIAVDTGRYWLTRLMSRAESEGMLRFRAWLFAEVAAAGA

Specific function: This protein is a positive regulator of gene expression of beta-lactamase (AmpC) [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789173, Length=288, Percent_Identity=39.2361111111111, Blast_Score=189, Evalue=1e-49,
Organism=Escherichia coli, GI1786448, Length=288, Percent_Identity=32.9861111111111, Blast_Score=140, Evalue=1e-34,
Organism=Escherichia coli, GI1788706, Length=296, Percent_Identity=31.7567567567568, Blast_Score=127, Evalue=8e-31,
Organism=Escherichia coli, GI1787128, Length=146, Percent_Identity=34.2465753424658, Blast_Score=88, Evalue=6e-19,
Organism=Escherichia coli, GI145693193, Length=193, Percent_Identity=29.0155440414508, Blast_Score=82, Evalue=4e-17,
Organism=Escherichia coli, GI1787589, Length=254, Percent_Identity=25.9842519685039, Blast_Score=81, Evalue=9e-17,
Organism=Escherichia coli, GI1790262, Length=214, Percent_Identity=28.9719626168224, Blast_Score=76, Evalue=2e-15,
Organism=Escherichia coli, GI87081978, Length=291, Percent_Identity=27.1477663230241, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI1786401, Length=243, Percent_Identity=26.3374485596708, Blast_Score=69, Evalue=4e-13,
Organism=Escherichia coli, GI157672245, Length=163, Percent_Identity=33.1288343558282, Blast_Score=62, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 31483; Mature: 31483

Theoretical pI: Translated: 7.71; Mature: 7.71

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDRAQLPLNALRAFEAAARHLNFTRAGLELCVSQGAVSHQVAALERRLGTRLFHRLPRGL
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCC
ALTDEGHALVPVVSEAFDRVAATLDQYADGRFRETLKVGVVGTFATGWLMPRLDAFSRAH
EECCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHEEHHHHHHHHHHHHHHHHCCC
PSIDLRIATNNNRVDLAGEGLDYAIRFGDGAWHGTHAEPLLDAPMAPICAPVVAARLRTP
CCEEEEEEECCCEEEEECCCCEEEEEECCCCCCCCCCCCHHCCCCHHHHHHHHHHHHCCC
ADLASERLLRSYRADEWALWFGAAGIAAPVMRGPVFDSSALMAAAAAAGQGVALAPPSMF
HHHHHHHHHHHHCCCCEEEEECHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCEECCHHHH
TRELAAELLVQPFAIAVDTGRYWLTRLMSRAESEGMLRFRAWLFAEVAAAGA
HHHHHHHHHHCCHHEEEECCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MDRAQLPLNALRAFEAAARHLNFTRAGLELCVSQGAVSHQVAALERRLGTRLFHRLPRGL
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCC
ALTDEGHALVPVVSEAFDRVAATLDQYADGRFRETLKVGVVGTFATGWLMPRLDAFSRAH
EECCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHEEHHHHHHHHHHHHHHHHCCC
PSIDLRIATNNNRVDLAGEGLDYAIRFGDGAWHGTHAEPLLDAPMAPICAPVVAARLRTP
CCEEEEEEECCCEEEEECCCCEEEEEECCCCCCCCCCCCHHCCCCHHHHHHHHHHHHCCC
ADLASERLLRSYRADEWALWFGAAGIAAPVMRGPVFDSSALMAAAAAAGQGVALAPPSMF
HHHHHHHHHHHHCCCCEEEEECHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCEECCHHHH
TRELAAELLVQPFAIAVDTGRYWLTRLMSRAESEGMLRFRAWLFAEVAAAGA
HHHHHHHHHHCCHHEEEECCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8405939; 10984043; 2125210 [H]