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The map label for this gene is accA

Identifier: 103487280

GI number: 103487280

Start: 1892029

End: 1892976

Strand: Reverse

Name: accA

Synonym: Sala_1796

Alternate gene names: 103487280

Gene position: 1892976-1892029 (Counterclockwise)

Preceding gene: 103487281

Following gene: 103487279

Centisome position: 56.59

GC content: 65.4

Gene sequence:

>948_bases
ATGACAGCCTTTCTGGACTTCGAAAAACAGGTCGCCGCACTCGATCGACAGATTGCCGAACTGCGCGAAATGGGGGATGA
TCCCACGCTCGATATCGAGGGCGACATCGCCAGGCTGGAGGACAAGTCCGCCAAATTGCTGCGCGACATCTATGCCAGGC
TGACGCCGTGGCAGAAAACGCAGGTCGCGCGTCACCCCGACCGGCCGCATTTCAAACATTATGTCGCGGGCCTGTTCGAC
GACTGGATGCCGCTCGCGGGCGACCGCAATTTTGCCGACGATCAGGCGATTCTGGGCGGGCTGGCGCGGTTCCGGGGCCG
CCGCGTGATGGTGATCGGCCATGAAAAGGGCGACGATATTCCGTCGCGGATGAAGCATAATTTCGGCATGGCAAAGCCCG
AAGGCTATCGAAAGGCGATCCGGCTGATGCAGCTTGCCGACCGCTTCGGCCTGCCCGTGATAACGCTGGTCGATACGTCG
GGCGCCTTTCCCGGCATCCAGGCCGAGGAGCGCGGACAGGCCGAAGCGATCGCGCGGTCGACCGAACAGTGCCTTGCACT
GGGCGTGCCGATGGTCGCGGCGGTGGTCGGCGAGGGCGGTTCGGGCGGCGCGATCGCGCTCGCCGCGGCAAACCGCGTGC
TGATGTTCGAGCACGCCGTCTATTCGGTGATCTCTCCCGAGGGTTGCGCCTCGATCCTGTGGCGCACCTCGGACAAGGCG
GCGGAGGCGGCGGCAGCGATGAAGATGTCGGCGCAGGATCTGCTGGCGCTGAAGATCATCGACCGGATCGTTCCCGAACC
CGTCGGCGGCGCGCATCGCGCGCCCGAGGCTGCGATTGCCGCGCTCGGCGATGCCCTCGAACAGGAACTGAACGGCCTGT
CGGGCCTGCCGCGCGACACATTGCTTGCCGCGCGAGAGGAAAAGTTCCTCGCGATGGGCCGCGCCTGA

Upstream 100 bases:

>100_bases
TGTCGACAGCCGCCGCCTCGTCGAACTGGTCAACCGGCGGCACCCGCTGGCGCATATGGATGACGTTGACCTGACGGCGC
CTTCGGCCTAGCGACGGCGC

Downstream 100 bases:

>100_bases
CGAGAGCGGAACCGTTCCGCCCTGTCAGCGTTCCCTTTATCGGATACAGGGTAAACGACGGTCGTGGCGGTCGCTTATTT
TTTGCAATGACAGGGATATC

Product: acetyl-CoA carboxylase carboxyltransferase subunit alpha

Products: NA

Alternate protein names: ACCase subunit alpha; Acetyl-CoA carboxylase carboxyltransferase subunit alpha

Number of amino acids: Translated: 315; Mature: 314

Protein sequence:

>315_residues
MTAFLDFEKQVAALDRQIAELREMGDDPTLDIEGDIARLEDKSAKLLRDIYARLTPWQKTQVARHPDRPHFKHYVAGLFD
DWMPLAGDRNFADDQAILGGLARFRGRRVMVIGHEKGDDIPSRMKHNFGMAKPEGYRKAIRLMQLADRFGLPVITLVDTS
GAFPGIQAEERGQAEAIARSTEQCLALGVPMVAAVVGEGGSGGAIALAAANRVLMFEHAVYSVISPEGCASILWRTSDKA
AEAAAAMKMSAQDLLALKIIDRIVPEPVGGAHRAPEAAIAALGDALEQELNGLSGLPRDTLLAAREEKFLAMGRA

Sequences:

>Translated_315_residues
MTAFLDFEKQVAALDRQIAELREMGDDPTLDIEGDIARLEDKSAKLLRDIYARLTPWQKTQVARHPDRPHFKHYVAGLFD
DWMPLAGDRNFADDQAILGGLARFRGRRVMVIGHEKGDDIPSRMKHNFGMAKPEGYRKAIRLMQLADRFGLPVITLVDTS
GAFPGIQAEERGQAEAIARSTEQCLALGVPMVAAVVGEGGSGGAIALAAANRVLMFEHAVYSVISPEGCASILWRTSDKA
AEAAAAMKMSAQDLLALKIIDRIVPEPVGGAHRAPEAAIAALGDALEQELNGLSGLPRDTLLAAREEKFLAMGRA
>Mature_314_residues
TAFLDFEKQVAALDRQIAELREMGDDPTLDIEGDIARLEDKSAKLLRDIYARLTPWQKTQVARHPDRPHFKHYVAGLFDD
WMPLAGDRNFADDQAILGGLARFRGRRVMVIGHEKGDDIPSRMKHNFGMAKPEGYRKAIRLMQLADRFGLPVITLVDTSG
AFPGIQAEERGQAEAIARSTEQCLALGVPMVAAVVGEGGSGGAIALAAANRVLMFEHAVYSVISPEGCASILWRTSDKAA
EAAAAMKMSAQDLLALKIIDRIVPEPVGGAHRAPEAAIAALGDALEQELNGLSGLPRDTLLAAREEKFLAMGRA

Specific function: Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-Co

COG id: COG0825

COG function: function code I; Acetyl-CoA carboxylase alpha subunit

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the AccA family

Homologues:

Organism=Escherichia coli, GI1786382, Length=315, Percent_Identity=51.7460317460318, Blast_Score=319, Evalue=1e-88,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ACCA_SPHAL (Q1GS64)

Other databases:

- EMBL:   CP000356
- RefSeq:   YP_616841.1
- ProteinModelPortal:   Q1GS64
- SMR:   Q1GS64
- GeneID:   4082264
- GenomeReviews:   CP000356_GR
- KEGG:   sal:Sala_1796
- NMPDR:   fig|317655.9.peg.1726
- HOGENOM:   HBG286557
- OMA:   QLTKDIY
- ProtClustDB:   PRK05724
- BioCyc:   SALA317655:SALA_1796-MONOMER
- BRENDA:   6.4.1.2
- HAMAP:   MF_00823
- InterPro:   IPR001095
- InterPro:   IPR011763
- PANTHER:   PTHR22855:SF3
- PRINTS:   PR01069
- TIGRFAMs:   TIGR00513

Pfam domain/function: PF03255 ACCA

EC number: =6.4.1.2

Molecular weight: Translated: 34105; Mature: 33973

Theoretical pI: Translated: 5.94; Mature: 5.94

Prosite motif: PS50989 COA_CT_CTER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTAFLDFEKQVAALDRQIAELREMGDDPTLDIEGDIARLEDKSAKLLRDIYARLTPWQKT
CCCCHHHHHHHHHHHHHHHHHHHCCCCCCEECCCCHHHHHHHHHHHHHHHHHHCCCCHHH
QVARHPDRPHFKHYVAGLFDDWMPLAGDRNFADDQAILGGLARFRGRRVMVIGHEKGDDI
HHHCCCCCCHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHCCCEEEEEECCCCCCH
PSRMKHNFGMAKPEGYRKAIRLMQLADRFGLPVITLVDTSGAFPGIQAEERGQAEAIARS
HHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCHHCCHHHHHHHH
TEQCLALGVPMVAAVVGEGGSGGAIALAAANRVLMFEHAVYSVISPEGCASILWRTSDKA
HHHHHHHHHHHHHHHHCCCCCCCEEEEECCCHHHHHHHHHHHHCCCCHHHHHHHCCCHHH
AEAAAAMKMSAQDLLALKIIDRIVPEPVGGAHRAPEAAIAALGDALEQELNGLSGLPRDT
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCHHH
LLAAREEKFLAMGRA
HHHHHHHHHHHCCCC
>Mature Secondary Structure 
TAFLDFEKQVAALDRQIAELREMGDDPTLDIEGDIARLEDKSAKLLRDIYARLTPWQKT
CCCHHHHHHHHHHHHHHHHHHHCCCCCCEECCCCHHHHHHHHHHHHHHHHHHCCCCHHH
QVARHPDRPHFKHYVAGLFDDWMPLAGDRNFADDQAILGGLARFRGRRVMVIGHEKGDDI
HHHCCCCCCHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHCCCEEEEEECCCCCCH
PSRMKHNFGMAKPEGYRKAIRLMQLADRFGLPVITLVDTSGAFPGIQAEERGQAEAIARS
HHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCHHCCHHHHHHHH
TEQCLALGVPMVAAVVGEGGSGGAIALAAANRVLMFEHAVYSVISPEGCASILWRTSDKA
HHHHHHHHHHHHHHHHCCCCCCCEEEEECCCHHHHHHHHHHHHCCCCHHHHHHHCCCHHH
AEAAAAMKMSAQDLLALKIIDRIVPEPVGGAHRAPEAAIAALGDALEQELNGLSGLPRDT
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCHHH
LLAAREEKFLAMGRA
HHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA